Solubility, Solution Thermodynamics, and Preferential Solvation of Amygdalin in Ethanol + Water Solvent Mixtures

Se informó la solubilidad en equilibrio de la amigdalina en mezclas de [etanol (1) + agua (2)] a 293,15 K a 328,15 K. Las propiedades termodinámicas (entalpía estándar Δ soln H °, entropía estándar Δ soln S ° y energía de Gibbs estándar de la solución Δ solnG °) se calcularon utilizando los datos de...

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Autores:: Aydi, Abdelkarim
Ayadi, Cherifa
Ghachem, Kaouther
Al-Khazaal, Abdulaal Z.
Delgado, Daniel Ricardo
Alnaief, Mohammad
Kolsi, Lioua

Tipo de recurso:: Article of journal

Fecha de publicación:: 2020

Institución:: Universidad Cooperativa de Colombia

Repositorio:: Repositorio UCC

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repository_id_str
dc.title.spa.fl_str_mv	Solubility, Solution Thermodynamics, and Preferential Solvation of Amygdalin in Ethanol + Water Solvent Mixtures
title	Solubility, Solution Thermodynamics, and Preferential Solvation of Amygdalin in Ethanol + Water Solvent Mixtures
spellingShingle	Solubility, Solution Thermodynamics, and Preferential Solvation of Amygdalin in Ethanol + Water Solvent Mixtures Amigdalina Integral de Kirkwood-Buff inversa Termodinámica Van't Hoff Ecuación de Gibbs Solubilidad Jouyban – Acree Buchowski – Ksiazczak Amygdalin Gibbs equation Van’t Hoff Thermodynamics Solubility Jouyban–Acree Buchowski–Ksiazczak Inverse Kirkwood–Buff integral
title_short	Solubility, Solution Thermodynamics, and Preferential Solvation of Amygdalin in Ethanol + Water Solvent Mixtures
title_full	Solubility, Solution Thermodynamics, and Preferential Solvation of Amygdalin in Ethanol + Water Solvent Mixtures
title_fullStr	Solubility, Solution Thermodynamics, and Preferential Solvation of Amygdalin in Ethanol + Water Solvent Mixtures
title_full_unstemmed	Solubility, Solution Thermodynamics, and Preferential Solvation of Amygdalin in Ethanol + Water Solvent Mixtures
title_sort	Solubility, Solution Thermodynamics, and Preferential Solvation of Amygdalin in Ethanol + Water Solvent Mixtures
dc.creator.fl_str_mv	Aydi, Abdelkarim Ayadi, Cherifa Ghachem, Kaouther Al-Khazaal, Abdulaal Z. Delgado, Daniel Ricardo Alnaief, Mohammad Kolsi, Lioua
dc.contributor.author.none.fl_str_mv	Aydi, Abdelkarim Ayadi, Cherifa Ghachem, Kaouther Al-Khazaal, Abdulaal Z. Delgado, Daniel Ricardo Alnaief, Mohammad Kolsi, Lioua
dc.subject.spa.fl_str_mv	Amigdalina Integral de Kirkwood-Buff inversa Termodinámica Van't Hoff Ecuación de Gibbs Solubilidad Jouyban – Acree Buchowski – Ksiazczak
topic	Amigdalina Integral de Kirkwood-Buff inversa Termodinámica Van't Hoff Ecuación de Gibbs Solubilidad Jouyban – Acree Buchowski – Ksiazczak Amygdalin Gibbs equation Van’t Hoff Thermodynamics Solubility Jouyban–Acree Buchowski–Ksiazczak Inverse Kirkwood–Buff integral
dc.subject.other.spa.fl_str_mv	Amygdalin Gibbs equation Van’t Hoff Thermodynamics Solubility Jouyban–Acree Buchowski–Ksiazczak Inverse Kirkwood–Buff integral
description	Se informó la solubilidad en equilibrio de la amigdalina en mezclas de [etanol (1) + agua (2)] a 293,15 K a 328,15 K. Las propiedades termodinámicas (entalpía estándar Δ soln H °, entropía estándar Δ soln S ° y energía de Gibbs estándar de la solución Δ solnG °) se calcularon utilizando los datos de solubilidad generados mediante las ecuaciones de van't Hoff y Gibbs. El proceso de disolución de la amigdalina es endotérmico y el mecanismo impulsor de todas las mezclas es la entropía. La solubilidad máxima se logró en 0,4 moles de fracción de etanol a 328,15 K y la mínima en etanol puro a 293,15 K. Se utilizaron modelos de Van't Hoff, Jouyban-Acree-van't Hoff y Buchowski-Ksiazczak para simular la solubilidad obtenida datos. Las solubilidades calculadas se desvían razonablemente de los datos experimentales. Los parámetros de solvatación preferenciales de amigdalina en mezclas de disolventes se analizaron utilizando el método de integrales inversas de Kirkwood-Buff (IKBI). La amigdalina se solvata preferentemente con agua en mezclas ricas en etanol, mientras que en mezclas ricas en agua,
publishDate	2020
dc.date.accessioned.none.fl_str_mv	2020-11-25T19:52:38Z
dc.date.available.none.fl_str_mv	2020-11-01 2020-11-25T19:52:38Z
dc.date.issued.none.fl_str_mv	2020-11-14
dc.type.none.fl_str_mv	Artículo
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dc.identifier.issn.spa.fl_str_mv	14248247
dc.identifier.uri.spa.fl_str_mv	https://doi.org/10.3390/ph13110395
dc.identifier.uri.none.fl_str_mv	https://hdl.handle.net/20.500.12494/28273
dc.identifier.bibliographicCitation.spa.fl_str_mv	Aydi, A.; Ayadi, C.; Ghachem, K.; Al-Khazaal, A.Z.; Delgado, D.R.; Alnaief, M.; Kolsi, L. Solubility, Solution Thermodynamics, and Preferential Solvation of Amygdalin in Ethanol + Water Solvent Mixtures. Pharmaceuticals 2020, 13, 395.
identifier_str_mv	14248247 Aydi, A.; Ayadi, C.; Ghachem, K.; Al-Khazaal, A.Z.; Delgado, D.R.; Alnaief, M.; Kolsi, L. Solubility, Solution Thermodynamics, and Preferential Solvation of Amygdalin in Ethanol + Water Solvent Mixtures. Pharmaceuticals 2020, 13, 395.
url	https://doi.org/10.3390/ph13110395 https://hdl.handle.net/20.500.12494/28273
dc.relation.isversionof.spa.fl_str_mv	https://www.mdpi.com/1424-8247/13/11/395
dc.relation.ispartofjournal.spa.fl_str_mv	Pharmaceuticals
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In Fluctuation Theory of Solutions: Applications in Chemistry, Chemical Engineering, and Biophysics; CRC Press: Boca Raton, FL, USA, 2013; pp. 65–92 Marcus, Y. Preferential solvation of drugs in binary solvent mixtures. Pharm. Anal. Acta 2017, 8, 537. Yalkowsky, S.H. Solubility and Solubilization in Aqueous Media; American Chemical Society: New York, USA, 1999. Williams, R.O., III; Watts, A.B.; Miller, D.A. Formulating Poorly Water Soluble Drugs; American Association of Pharmaceutical Scientists: Austin, TX, USA, 2016. Delgado, D.R.; Rodríguez, G.A.; Martínez, F. Thermodynamic study of the solubility of sulfapyridine in some ethanol + water mixtures. J. Mol. Liq. 2013, 177, 156–161. Muñoz, M.d.; Delgado, D.R.; Peña, M.Á.; Jouyban, A.; Martínez, F. Solubility and preferential solvation of sulfadiazine, sulfamerazine and sulfamethazine in propylene glycol + water mixtures at 298.15 K. J. Mol. Liq. 2015, 204, 132–136. Barton, A. CRC Handbook of Solubility Parameters and Other Cohesion Parameters, 2nd ed.; CRC Press: New York, NY, USA, 1991. Delgado, D.R.; Mogollon-Waltero, E.M.; Ortiz, C.P.; Peña, M.; Almanza, O.A.; Martínez, F.; Jouyban, A. Enthalpy-entropy compensation analysis of the triclocarban dissolution process in some {1,4-dioxane (1) + water (2)} mixtures. J. Mol. Liq. 2018, 271, 522–529. Hildebtand, J.H.; Prausnitz, J.M.; Scott, R.L. Regular and Related Solutions: The Solubility of Gases, Liquids, and Solids; Van Nostrand Reinhold Company: New Tork, NY, USA, 1970. Grant, D.J.W.; Mehdizadeh, M.; Chow, A.H.L.; Fairbrother, J.E. Non-linear van’t Hoff solubility-temperature plots and their pharmaceutical interpretation. Int. J. Pharm. 1984, 18, 25–38. Jouyban, A.; Acree, W.E. Mathematical derivation of the Jouyban-Acree model to represent solute solubility data in mixed solvents at various temperatures. J. Mol. Liq. 2018, 256, 541–547. Ruidiaz, M.; Delgado, D.R.; Martínez, F. 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Ben-Naim, A.; Navarro, A.M.; Leal, J.M. A Kirkwood-Buff analysis of local properties of solutions. Phys. Chem. Chem. Phys. 2008, 10, 2451–2460. Marcus, Y. Solvent Mixtures: Properties and Selective Solvation; CRC Press: New York, NY, USA, 2002. Marcus, Y. On the preferential solvation of drugs and PAHs in binary solvent mixtures. J. Mol. Liq. 2008, 140, 61–67. Delgado, D.R.; Vargas, E.F.; Martínez, F. Preferential solvation of xylitol in ethanol + water co-solvent mixtures according to the IKBI and QLQC methods. Rev. Colomb. Quim. 2013, 42, 125–133. Marcus, Y. Preferential solvation in mixed solvents. 16. Mixtures of N,N-dimethylformamide or propylene carbonate with organic solvents. J. Chem. Thermodyn. 2020, 140, 105903. Delgado, D.R.; Peña, M.A.; Martínez, F. Preferential solvation of acetaminophen in ethanol + water solvent mixtures according to the inverse Kirkwood-Buff integrals method. Rev. Colomb Cienc. Químico Farm. 2013, 42, 298–314. Marcus, Y. Preferential solvation in mixed solvents. 15. Mixtures of acetonitrile with organic solvents. J. Chem. Thermodyn. 2019, 135, 55–59. Castro, J.J.S.; Ortiz, C.P.; Rodríguez-Rubiano, J.D.; Rodríguez-Rodríguez, G.A.; Delgado, D.R. Preferential solvation of tricin in {ethanol (1) + water (2)} mixtures at several temperatures. Rev. Colomb. Cienc. Químico Farm. 2018, 47, 135–148. Marcus, Y. Preferential solvation. Part 3.—Binary solvent mixtures. J. Chem. Soc. Faraday Trans. 1 Phys. Chem. Condens. Phases. 1989, 85, 381–388. Marcus, Y. The Properties of Solvents; John Wiley & Sons Ltd.: New York, NY, USA, 1999. Jiménez, J.; Manrique, J.; Martínez, F. Effect of temperature on some volumetric properties for ethanol + water mixtures. Rev. Colomb. Cienc. Químico Farm. 2004, 33, 145–155. Aldana, G.A.d.A.; Rubio, D.I.C.; Rodríguez, G.A.R.; Lozano, A.C.; Mehrdad, A.; Delgado, D.R.; Carmona, N.A.P. 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spelling	Aydi, AbdelkarimAyadi, CherifaGhachem, KaoutherAl-Khazaal, Abdulaal Z.Delgado, Daniel RicardoAlnaief, MohammadKolsi, Lioua132020-11-25T19:52:38Z2020-11-012020-11-25T19:52:38Z2020-11-1414248247https://doi.org/10.3390/ph13110395https://hdl.handle.net/20.500.12494/28273Aydi, A.; Ayadi, C.; Ghachem, K.; Al-Khazaal, A.Z.; Delgado, D.R.; Alnaief, M.; Kolsi, L. Solubility, Solution Thermodynamics, and Preferential Solvation of Amygdalin in Ethanol + Water Solvent Mixtures. Pharmaceuticals 2020, 13, 395.Se informó la solubilidad en equilibrio de la amigdalina en mezclas de [etanol (1) + agua (2)] a 293,15 K a 328,15 K. Las propiedades termodinámicas (entalpía estándar Δ soln H °, entropía estándar Δ soln S ° y energía de Gibbs estándar de la solución Δ solnG °) se calcularon utilizando los datos de solubilidad generados mediante las ecuaciones de van't Hoff y Gibbs. El proceso de disolución de la amigdalina es endotérmico y el mecanismo impulsor de todas las mezclas es la entropía. La solubilidad máxima se logró en 0,4 moles de fracción de etanol a 328,15 K y la mínima en etanol puro a 293,15 K. Se utilizaron modelos de Van't Hoff, Jouyban-Acree-van't Hoff y Buchowski-Ksiazczak para simular la solubilidad obtenida datos. Las solubilidades calculadas se desvían razonablemente de los datos experimentales. Los parámetros de solvatación preferenciales de amigdalina en mezclas de disolventes se analizaron utilizando el método de integrales inversas de Kirkwood-Buff (IKBI). La amigdalina se solvata preferentemente con agua en mezclas ricas en etanol, mientras que en mezclas ricas en agua,The equilibrium solubility of amygdalin in [ethanol (1) + water (2)] mixtures at 293.15 K to 328.15 K was reported. The thermodynamic properties (standard enthalpy ΔsolnH°, standard entropy ΔsolnS°, and standard Gibbs energy of solution ΔsolnG°) were computed using the generated solubility data via van’t Hoff and Gibbs equations. The dissolution process of amygdalin is endothermic and the driving mechanism in all mixtures is entropy. Maximal solubility was achieved in 0.4 mole fraction of ethanol at 328.15 K and the minimal one in neat ethanol at 293.15 K. Van’t Hoff, Jouyban–Acree–van’t Hoff, and Buchowski–Ksiazczak models were used to simulate the obtained solubility data. The calculated solubilities deviate reasonably from experimental data. Preferential solvation parameters of amygdalin in mixture solvents were analyzed using the inverse Kirkwood–Buff integrals (IKBI) method. Amygdalin is preferentially solvated by water in ethanol-rich mixtures, whereas in water-rich mixtures, there is no clear evidence that determines which of water or ethanol solvents would be most likely to solvate the molecule.1. Introduction. -- 2. Results and Discussion. -- 3. Experimental procedures. --4. 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Liq. 2019, 274, 752–758.AmigdalinaIntegral de Kirkwood-Buff inversaTermodinámicaVan't HoffEcuación de GibbsSolubilidadJouyban – AcreeBuchowski – KsiazczakAmygdalinGibbs equationVan’t HoffThermodynamicsSolubilityJouyban–AcreeBuchowski–KsiazczakInverse Kirkwood–Buff integralSolubility, Solution Thermodynamics, and Preferential Solvation of Amygdalin in Ethanol + Water Solvent MixturesArtículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAtribucióninfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2PublicationORIGINAL2020_Solubility_thermodynamics.Preferential.pdf2020_Solubility_thermodynamics.Preferential.pdfArtículo científicoapplication/pdf2479436https://repository.ucc.edu.co/bitstreams/989499b7-22ab-48b0-b297-f134df0d18f7/downloadef979fcc34aed0f15b865cce3634a93eMD51LICENSElicense.txtlicense.txttext/plain; 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Solubility, Solution Thermodynamics, and Preferential Solvation of Amygdalin in Ethanol + Water Solvent Mixtures

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