Venomic, Transcriptomic, and Bioactivity Analyses of Pamphobeteus verdolaga Venom Reveal Complex Disulfide-Rich Peptides That Modulate Calcium Channels

Pamphobeteus verdolaga is a recently described Theraphosidae spider from the Andean region of Colombia. Previous reports partially characterized its venom profile. In this study, we conducted a detailed analysis that includes reversed-phase high-performance liquid chromatography (rp-HPLC), calcium i...

Full description

Autores:

Estrada Gomez, Sebastian
Caldas Cardoso, Fernanda
Vargas Muñoz, Leidy Johana
Quintana Castillo, Juan Carlos
Arenas Gómez, Claudia Marcela
Pineda, Sandy Steffany
Saldarriaga Cordoba, Monica Maria

Tipo de recurso:

Article of journal

Fecha de publicación:

2023

Institución:

Universidad Cooperativa de Colombia

Repositorio:

Repositorio UCC

Idioma:

OAI Identifier:

oai:repository.ucc.edu.co:20.500.12494/50841

Acceso en línea:

https://doi.org/doi.org/10.3390/toxins11090496
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071652937&doi=10.3390%2ftoxins11090496&partnerID=40&md5=3d9045d553ead0e2a35dd6a062ccefa7
https://hdl.handle.net/20.500.12494/50841

Palabra clave:

DISULFIDE-RICH PEPTIDE (DRP)
INHIBITORY CYSTEINE KNOT (ICK)
ION CHANNELS
PAMPHOBETEUS
PEPTIDES
THERAPHOSIDAE
TRANSCRIPTOME
VENOMICS

Rights

openAccess

License

http://purl.org/coar/access_right/c_abf2