High-throughput sequencing reveals circulating miRNAs as potential biomarkers of kidney damage in patients with systemic lupus erythematosus

Renal involvement is one of the most severe manifestations of systemic lupus erythematosus (SLE). Renal biopsy is the gold standard when it comes to knowing whether a patient has lupus nephritis, and the degree of renal disease present. However, the biopsy has various complications, bleeding being t...

Full description

Autores:

Navarro-Quiroz E.
Pacheco-Lugo L.
Lorenzi H.
Díaz-Olmos Y.
Almendrales L.
Rico E.
Navarro Quiroz, Roberto Carlos
España-Puccini P.
Iglesias A.
Egea E.
Aroca G.

Tipo de recurso:

Article of journal

Fecha de publicación:

2016

Institución:

Universidad Cooperativa de Colombia

Repositorio:

Repositorio UCC

Idioma:

OAI Identifier:

oai:repository.ucc.edu.co:20.500.12494/41905

Acceso en línea:

https://doi.org/10.17533/udea.rfnsp.v35n1a10
https://hdl.handle.net/20.500.12494/41905

Palabra clave:

microRNA
microRNA 221 5p
microRNA 3074 3p
microRNA 380 3p
microRNA 556 5p
microRNA 758 3p
unclassified drug
biological marker
microRNA
MIRN221 microRNA
human
MIRN3074 microRNA
human
MIRN380 microRNA
human
MIRN556 microRNA
human
MIRN758 microRNA
human
area under the curve
Article
blood sampling
case control study
cross-sectional study
diagnostic accuracy
diagnostic test accuracy study
disease association
disease marker
gene expression
high throughput screening
human
human cell
kidney injury
observational study
polymerase chain reaction
predictive value
receiver operating characteristic
sensitivity and specificity
systemic lupus erythematosus
validity
adult
blood
female
gene expression profiling
genetics
high throughput sequencing
lupus erythematosus nephritis
male
middle aged
principal component analysis
procedures
reverse transcription polymerase chain reaction
systemic lupus erythematosus
young adult
Adult
Biomarkers
Female
Gene

Rights

closedAccess

License

http://purl.org/coar/access_right/c_14cb