In vitro anti-HIV-1 activity of the enzymatic extract enriched with laccase produced by the fungi ganoderma sp. and lentinus sp.
Background: Natural compounds are a good source for the development of antiretroviral drugs with low cytotoxicity. The laccase enzyme, produced by fungi of the genera Ganoderma sp. and Lentinus sp., inhibits the reverse transcriptase (RT) of the human immunodeficiency virus 1 (HIV-1), in cell-free m...
- Autores:
-
Flórez-Sampedro L.
Zapata Builes, Wildeman
Orozco L.P.
Mejía A.I.
Arboleda C.
Rugeles M.T.
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2016
- Institución:
- Universidad Cooperativa de Colombia
- Repositorio:
- Repositorio UCC
- Idioma:
- OAI Identifier:
- oai:repository.ucc.edu.co:20.500.12494/41978
- Palabra clave:
- antivirus agent
fungal extract
green fluorescent protein
hexadimethrine bromide
laccase
RNA directed DNA polymerase
antiviral activity
apoptosis
Article
cell proliferation
controlled study
cytotoxicity assay
enzyme linked immunosorbent assay
flow cytometry
Ganoderma
Human immunodeficiency virus 1
Lentinus
linear regression analysis
MTT assay
nonhuman
polymerase chain reaction
reverse transcription
ultraviolet spectrophotometry
virus recombinant
virus replication
- Rights
- closedAccess
- License
- http://purl.org/coar/access_right/c_14cb