Genetic factors associated to development of thrombocytopenia in preeclampsia.

Preeclampsia is a hypertensive disease that occurs after the 20 weeks of pregnancy, it is characterized by causing damage to various organs of the human body, mainly the liver and kidney, for this reason, it will be evidenced in laboratory tests: proteinuria, increased liver enzymes, hemolysis, olig...

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Fecha de publicación:: 2022

Institución:: Pontificia Universidad Javeriana Cali

Repositorio:: Vitela

Idioma:: spa

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spelling	Córdoba-García, Santiago2022-12-232023-10-11T04:34:53Z2023-10-11T04:34:53Zhttps://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/634https://vitela.javerianacali.edu.co/handle/11522/441Preeclampsia is a hypertensive disease that occurs after the 20 weeks of pregnancy, it is characterized by causing damage to various organs of the human body, mainly the liver and kidney, for this reason, it will be evidenced in laboratory tests: proteinuria, increased liver enzymes, hemolysis, oliguria, increased creatinine levels, thrombocytopenia, etc. The finding of thrombocytopenia during pregnancy always raises concern for clinicians due largely to the multiplicity of etiologies that must be considered to make a diagnosis. This topic review aims to analyze the presence of genetic factors that predispose or influence the development of thrombocytopenia in women with preeclampsia, highlighting to the reader the importance of prenatal controls in the prevention of diseases in pregnancy, keeping in mind risk factors associated with the development of pathologies in maternal and carry out the appropriate treatment to avoid complications in the gestation period. A literature search was conducted in the MedLine (PubMed), Clinical Key, and Science Direct databases, without restriction in time or language, considering the articles that described the diagnostic aspects, the genetic factors involved in the development of thrombocytopenia in preeclampsia, obtaining 57 articles after their selection process.La preeclampsia es una enfermedad hipertensiva que ocurre después de la semana 20 del embarazo, se caracteriza por causar daños en varios órganos del cuerpo humano, principalmente en el hígado y riñón, en razón a ello se evidenciara en los exámenes de laboratorio: proteinuria, aumento de las enzimas hepáticas, hemolisis, oliguria, aumento de los niveles de creatinina, trombocitopenia, etc. El hallazgo de una trombocitopenia durante la gestación siempre genera preocupación al personal clínico debido en gran parte a la multiplicidad de etiologías que se deben considerar para realizar un diagnóstico. En esta revisión de tema tiene como objetivo analizar la presencia de factores genéticos que predispones o influyen en el desarrollo de la trombocitopenia en mujeres con preeclampsia, destacándole al lector la importancia que tienen los controles prenatales en la prevención de enfermedades en el embarazo, tener presente factores de riegos asociados al desarrollo de patologías en las maternas y realiza el tratamiento oportuno para evitar complicaciones en el periodo de gestación. Se realizó una búsqueda en la literatura en las bases de datos MedLine (PubMed), Clinical Key y Science Direct, sin restricción en tiempo ni idioma, teniendo en cuenta los artículos que describieran los aspectos diagnósticos, los factores genéticos implicados en el desarrollo de trombocitopenia en la preeclampsia, obteniendo 57 artículos después del proceso de selección de los mismos.application/pdfspaPontificia Universidad Javeriana Calihttps://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/634/537Derechos de autor 2022 Salutem Scientia Spiritushttps://creativecommons.org/licenses/by-nc-nd/4.0Salutem Scientia Spiritus; Vol. 8 No. 4 (2022): Revista Salutem Scientia Spiritus; 77-83Salutem Scientia Spiritus; Vol. 8 Núm. 4 (2022): Revista Salutem Scientia Spiritus; 77-832463-1426TrombocitopeniaPreeclampsiaGenéticaMegacariopoyesisThrombocytopeniaPreeclampsiaGeneticMegakaryopoiesisGenetic factors associated to development of thrombocytopenia in preeclampsia.Factores genéticos asociados al desarrollo de trombocitopenia en la preeclampsia.info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRevisión de la literatura11522/441oai:vitela.javerianacali.edu.co:11522/4412024-06-25 05:12:42.271metadata.onlyhttps://vitela.javerianacali.edu.coRepositorio Vitelavitela.mail@javerianacali.edu.co
dc.title.en-US.fl_str_mv	Genetic factors associated to development of thrombocytopenia in preeclampsia.
dc.title.es-ES.fl_str_mv	Factores genéticos asociados al desarrollo de trombocitopenia en la preeclampsia.
title	Genetic factors associated to development of thrombocytopenia in preeclampsia.
spellingShingle	Genetic factors associated to development of thrombocytopenia in preeclampsia. Córdoba-García, Santiago Trombocitopenia Preeclampsia Genética Megacariopoyesis Thrombocytopenia Preeclampsia Genetic Megakaryopoiesis
title_short	Genetic factors associated to development of thrombocytopenia in preeclampsia.
title_full	Genetic factors associated to development of thrombocytopenia in preeclampsia.
title_fullStr	Genetic factors associated to development of thrombocytopenia in preeclampsia.
title_full_unstemmed	Genetic factors associated to development of thrombocytopenia in preeclampsia.
title_sort	Genetic factors associated to development of thrombocytopenia in preeclampsia.
dc.creator.none.fl_str_mv	Córdoba-García, Santiago
author	Córdoba-García, Santiago
author_facet	Córdoba-García, Santiago
author_role	author
dc.subject.es-ES.fl_str_mv	Trombocitopenia Preeclampsia Genética Megacariopoyesis
topic	Trombocitopenia Preeclampsia Genética Megacariopoyesis Thrombocytopenia Preeclampsia Genetic Megakaryopoiesis
dc.subject.en-US.fl_str_mv	Thrombocytopenia Preeclampsia Genetic Megakaryopoiesis
description	Preeclampsia is a hypertensive disease that occurs after the 20 weeks of pregnancy, it is characterized by causing damage to various organs of the human body, mainly the liver and kidney, for this reason, it will be evidenced in laboratory tests: proteinuria, increased liver enzymes, hemolysis, oliguria, increased creatinine levels, thrombocytopenia, etc. The finding of thrombocytopenia during pregnancy always raises concern for clinicians due largely to the multiplicity of etiologies that must be considered to make a diagnosis. This topic review aims to analyze the presence of genetic factors that predispose or influence the development of thrombocytopenia in women with preeclampsia, highlighting to the reader the importance of prenatal controls in the prevention of diseases in pregnancy, keeping in mind risk factors associated with the development of pathologies in maternal and carry out the appropriate treatment to avoid complications in the gestation period. A literature search was conducted in the MedLine (PubMed), Clinical Key, and Science Direct databases, without restriction in time or language, considering the articles that described the diagnostic aspects, the genetic factors involved in the development of thrombocytopenia in preeclampsia, obtaining 57 articles after their selection process.
publishDate	2022
dc.date.accessioned.none.fl_str_mv	2023-10-11T04:34:53Z
dc.date.available.none.fl_str_mv	2023-10-11T04:34:53Z
dc.date.none.fl_str_mv	2022-12-23
dc.type.none.fl_str_mv	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion
dc.type.es-ES.fl_str_mv	Revisión de la literatura
status_str	publishedVersion
dc.identifier.none.fl_str_mv	https://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/634
dc.identifier.uri.none.fl_str_mv	https://vitela.javerianacali.edu.co/handle/11522/441
url	https://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/634 https://vitela.javerianacali.edu.co/handle/11522/441
dc.language.none.fl_str_mv	spa
language	spa
dc.relation.none.fl_str_mv	https://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/634/537
dc.rights.es-ES.fl_str_mv	Derechos de autor 2022 Salutem Scientia Spiritus https://creativecommons.org/licenses/by-nc-nd/4.0
rights_invalid_str_mv	Derechos de autor 2022 Salutem Scientia Spiritus https://creativecommons.org/licenses/by-nc-nd/4.0
dc.format.none.fl_str_mv	application/pdf
dc.publisher.es-ES.fl_str_mv	Pontificia Universidad Javeriana Cali
dc.source.en-US.fl_str_mv	Salutem Scientia Spiritus; Vol. 8 No. 4 (2022): Revista Salutem Scientia Spiritus; 77-83
dc.source.es-ES.fl_str_mv	Salutem Scientia Spiritus; Vol. 8 Núm. 4 (2022): Revista Salutem Scientia Spiritus; 77-83
dc.source.none.fl_str_mv	2463-1426
institution	Pontificia Universidad Javeriana Cali
repository.name.fl_str_mv	Repositorio Vitela
repository.mail.fl_str_mv	vitela.mail@javerianacali.edu.co
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Genetic factors associated to development of thrombocytopenia in preeclampsia.

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