Standardization of the morphogenetic periods of the cardiogenesis of Wistar rat (Rattus norvegicus)
Aim: To describe the morphogenetic cardiogenesis processes of the Wistar rat (Rattus norvegicus) in a vivarium located in Cali (Colombia). Materials and methods: observational-descriptive study of cross-section where the four morphogenetic processes of the heart development (cardiogenic field, cardi...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2021
- Institución:
- Pontificia Universidad Javeriana Cali
- Repositorio:
- Vitela
- Idioma:
- spa
- OAI Identifier:
- oai:vitela.javerianacali.edu.co:11522/505
- Acceso en línea:
- https://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/1289
https://vitela.javerianacali.edu.co/handle/11522/505
- Palabra clave:
- Rata Wistar
Embriología
Biología del desarrollo
Histología
Cardiogénesis
Corazón
Wistar Rat
Embriology
Developmental biology
Histology
Cardiogenesis
Heart
- Rights
- License
- Derechos de autor 2023 Salutem Scientia Spiritus
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| dc.title.en-US.fl_str_mv |
Standardization of the morphogenetic periods of the cardiogenesis of Wistar rat (Rattus norvegicus) |
| dc.title.es-ES.fl_str_mv |
Estandarización de los periodos morfogenéticos de la cardiogénesis de rata Wistar (Rattus norvegicus) |
| title |
Standardization of the morphogenetic periods of the cardiogenesis of Wistar rat (Rattus norvegicus) |
| spellingShingle |
Standardization of the morphogenetic periods of the cardiogenesis of Wistar rat (Rattus norvegicus) Ramírez-Soto, Natalya Rata Wistar Embriología Biología del desarrollo Histología Cardiogénesis Corazón Wistar Rat Embriology Developmental biology Histology Cardiogenesis Heart |
| title_short |
Standardization of the morphogenetic periods of the cardiogenesis of Wistar rat (Rattus norvegicus) |
| title_full |
Standardization of the morphogenetic periods of the cardiogenesis of Wistar rat (Rattus norvegicus) |
| title_fullStr |
Standardization of the morphogenetic periods of the cardiogenesis of Wistar rat (Rattus norvegicus) |
| title_full_unstemmed |
Standardization of the morphogenetic periods of the cardiogenesis of Wistar rat (Rattus norvegicus) |
| title_sort |
Standardization of the morphogenetic periods of the cardiogenesis of Wistar rat (Rattus norvegicus) |
| dc.creator.none.fl_str_mv |
Ramírez-Soto, Natalya Laverde-Sudupe, Nicolás Moreno-Gomez , Freddy |
| author |
Ramírez-Soto, Natalya |
| author_facet |
Ramírez-Soto, Natalya Laverde-Sudupe, Nicolás Moreno-Gomez , Freddy |
| author_role |
author |
| author2 |
Laverde-Sudupe, Nicolás Moreno-Gomez , Freddy |
| author2_role |
author author |
| dc.subject.es-ES.fl_str_mv |
Rata Wistar Embriología Biología del desarrollo Histología Cardiogénesis Corazón |
| topic |
Rata Wistar Embriología Biología del desarrollo Histología Cardiogénesis Corazón Wistar Rat Embriology Developmental biology Histology Cardiogenesis Heart |
| dc.subject.en-US.fl_str_mv |
Wistar Rat Embriology Developmental biology Histology Cardiogenesis Heart |
| description |
Aim: To describe the morphogenetic cardiogenesis processes of the Wistar rat (Rattus norvegicus) in a vivarium located in Cali (Colombia). Materials and methods: observational-descriptive study of cross-section where the four morphogenetic processes of the heart development (cardiogenic field, cardiac tube, cardiac loop and septum and compartmentalization) were described, through histochemical preparations in hematoxylin-eosin, of 76 embryos obtained from 22 females (one for each gestation day) from the ninth day of intrauterine development. Results: A comparative approximation was carried out between the gestational stages of the Wistar rat in days, and the weeks of heart development in humans, being 3 and 9 for the cardiogenic field, 4 and 11 for the cardiac tube, 4 and 12 for the cardiac loop and 5 and 13 for the septum and compartmentalization respectively, with a few variations due to reported literature. Conclusions: Identifying the morphogenetic processes of the cardiogenesis of the Wistar rat (Rattus norvegicus) in a vivarium located in Cali will allow the establishment of a space-time based line for the comparative embryonic study of the human heart development. The standardization of the four cardiogenetic periods in a Wistar rat biomodel enables the investigators to perform studies about the etiopathogenesis of congenital cardiac anomalies through comparative embryology. The identification of the gestational age where the morphogenetic processes take place contributes to diminish the unnecessary deaths of Wistar rat biomodels in future studies. |
| publishDate |
2021 |
| dc.date.accessioned.none.fl_str_mv |
2023-10-11T04:35:14Z |
| dc.date.available.none.fl_str_mv |
2023-10-11T04:35:14Z |
| dc.date.none.fl_str_mv |
2021-12-30 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| dc.type.es-ES.fl_str_mv |
Artículo de investigación original |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
https://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/1289 |
| dc.identifier.uri.none.fl_str_mv |
https://vitela.javerianacali.edu.co/handle/11522/505 |
| url |
https://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/1289 https://vitela.javerianacali.edu.co/handle/11522/505 |
| dc.language.none.fl_str_mv |
spa |
| language |
spa |
| dc.relation.none.fl_str_mv |
https://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/1289/1122 |
| dc.rights.es-ES.fl_str_mv |
Derechos de autor 2023 Salutem Scientia Spiritus https://creativecommons.org/licenses/by-nc-nd/4.0 |
| rights_invalid_str_mv |
Derechos de autor 2023 Salutem Scientia Spiritus https://creativecommons.org/licenses/by-nc-nd/4.0 |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.es-ES.fl_str_mv |
Pontificia Universidad Javeriana Cali |
| dc.source.en-US.fl_str_mv |
Salutem Scientia Spiritus; Vol. 7 No. 4 (2021): Revista Salutem Scientia Spiritus; 30-37 |
| dc.source.es-ES.fl_str_mv |
Salutem Scientia Spiritus; Vol. 7 Núm. 4 (2021): Revista Salutem Scientia Spiritus; 30-37 |
| dc.source.none.fl_str_mv |
2463-1426 |
| institution |
Pontificia Universidad Javeriana Cali |
| repository.name.fl_str_mv |
Repositorio Vitela |
| repository.mail.fl_str_mv |
vitela.mail@javerianacali.edu.co |
| _version_ |
1812095061444263936 |
| spelling |
Ramírez-Soto, NatalyaLaverde-Sudupe, NicolásMoreno-Gomez , Freddy2021-12-302023-10-11T04:35:14Z2023-10-11T04:35:14Zhttps://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/1289https://vitela.javerianacali.edu.co/handle/11522/505Aim: To describe the morphogenetic cardiogenesis processes of the Wistar rat (Rattus norvegicus) in a vivarium located in Cali (Colombia). Materials and methods: observational-descriptive study of cross-section where the four morphogenetic processes of the heart development (cardiogenic field, cardiac tube, cardiac loop and septum and compartmentalization) were described, through histochemical preparations in hematoxylin-eosin, of 76 embryos obtained from 22 females (one for each gestation day) from the ninth day of intrauterine development. Results: A comparative approximation was carried out between the gestational stages of the Wistar rat in days, and the weeks of heart development in humans, being 3 and 9 for the cardiogenic field, 4 and 11 for the cardiac tube, 4 and 12 for the cardiac loop and 5 and 13 for the septum and compartmentalization respectively, with a few variations due to reported literature. Conclusions: Identifying the morphogenetic processes of the cardiogenesis of the Wistar rat (Rattus norvegicus) in a vivarium located in Cali will allow the establishment of a space-time based line for the comparative embryonic study of the human heart development. The standardization of the four cardiogenetic periods in a Wistar rat biomodel enables the investigators to perform studies about the etiopathogenesis of congenital cardiac anomalies through comparative embryology. The identification of the gestational age where the morphogenetic processes take place contributes to diminish the unnecessary deaths of Wistar rat biomodels in future studies.Objetivo: Describir los procesos morfogenéticos de la cardiogénesis de rata Wistar (Rattus norvegicus) de un bioterio de Cali (Colombia). Materiales y métodos: Estudio observacional descriptivo de corte transversal en el que se describieron los cuatro períodos morfogenéticos del desarrollo del corazón (campo cardiógénico, tubo cardiaco, asa cardiaca y tabicación y compartimentalización), a través de preparaciones histoquímicas en hematoxilina-eosina, de 76 embriones obtenidos de 22 hembras (una para cada día de gestación) desde el día nueve de desarrollo intrauterino. Resultados: Se realizó una aproximación comparativa entre los estadios gestacionales en días de la rata Wistar y las semanas de desarrollo del corazón en humanos, siendo para el campo cardiógeno 3 y 9, para el tubo cardiaco 4 y 11, para el asa cardiaca 4 y 12 y para tabicación y compartimentalización 5 y 13, respectivamente, con algunas variaciones respecto a la literatura reportada. Conclusiones: La identificación de los procesos morfogenéticos de la cardiogénesis de rata Wistar (Rattus norvegicus) de un bioterio de Cali, permitirá establecer una línea de base espaciotemporal para el estudio embrionario comparativo del desarrollo del corazón humano. La estandarización de los cuatro períodos de la cardiogénesis en un biomodelo de rata Wistar permitirá realizar estudios sobre la etiopatogénesis de las anomalías congénitas cardiacas mediante embriología comparada. La identificación de la edad gestacional en la que se dan los procesos morfogenéticos contribuye a la reducción del número de muertes innecesarias de biomodelos de rata Wistar en futuros estudios.application/pdfspaPontificia Universidad Javeriana Calihttps://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/1289/1122Derechos de autor 2023 Salutem Scientia Spiritushttps://creativecommons.org/licenses/by-nc-nd/4.0Salutem Scientia Spiritus; Vol. 7 No. 4 (2021): Revista Salutem Scientia Spiritus; 30-37Salutem Scientia Spiritus; Vol. 7 Núm. 4 (2021): Revista Salutem Scientia Spiritus; 30-372463-1426Rata WistarEmbriologíaBiología del desarrolloHistologíaCardiogénesisCorazónWistar RatEmbriologyDevelopmental biologyHistologyCardiogenesisHeartStandardization of the morphogenetic periods of the cardiogenesis of Wistar rat (Rattus norvegicus)Estandarización de los periodos morfogenéticos de la cardiogénesis de rata Wistar (Rattus norvegicus)info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtículo de investigación original11522/505oai:vitela.javerianacali.edu.co:11522/5052024-06-25 05:12:43.256metadata.onlyhttps://vitela.javerianacali.edu.coRepositorio Vitelavitela.mail@javerianacali.edu.co |