Paracetamol poisoning in an adult patient: Case report and review of literature.

The acetaminophen (acetyl para-aminophenol n-) is a para-aminophenol derivative as phenacetin, maintaining, as this antipyretic and analgesic effect, besides antiinflammatory effects. It is a drug widely used in both adult and pediatric population. Previous studies of secondary poisoning consumption of this drug demonstrate that adult dose is 6 to 7 grams potentially having a possible toxic effect, the lethal dose is about 13 to 25 grams. In this paper we report the case of a 28-year-old female patient who consumes 36 paracetamol tablets (18 grams) due to a suicide attempt, which is carried out by internal medicine together with social work, psychology, and psychiatry. Management with saline solution, metoclopramide and N-acetylcysteine is started. The patient showed multiorgan compromise, acute hepatic failure, electrolyte imbalance, and psychotic symptoms, with evidence of neurological compromise.

• Fecha de publicación: 2022
• Institución: Pontificia Universidad Javeriana Cali
• Repositorio: Vitela
• Idioma: spa
• OAI Identifier: oai:vitela.javerianacali.edu.co:11522/457
• Acceso en línea: https://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/651; https://vitela.javerianacali.edu.co/handle/11522/457
• Palabra clave: Paracetamol; Intoxicación; Falla hepática; Encefalopatía; N-acetilcisteína; Paracetamol; Poisoning; Liver Failure; Encephalopathy; N-acetyl cysteine
• License: Derechos de autor 2023 Salutem Scientia Spiritus