Relationship between the colonization of the intestinal microbiota and the development of intestinal inflammatory pathologies. Narrative literature review.

Inflammatory bowel diseases, defined as chronic intestinal inflammation and where the immune system intervenes, constitute two main disorders: ulcerative colitis and Crohn's disease. In the first, the colon is affected and is characterized by inflammation of the mucous tunic; while in the second, any part of the gastrointestinal tract (from the oral cavity to the anus) can be affected and is characterized by transmural inflammation. In both, the existence of an abnormal activation of the immune system associated with the mucosa against commensal bacteria of the enteric tract is known –due to an infectious process against an environmental trigger in individuals with genetic susceptibility–, to which it has been attributed a growing incidence of morbidity worldwide. Although the etiopathogenic mechanism is completely unknown, the alteration of the intestinal microbiota has been considered a new factor involved in the pathogenesis of the disease. Therefore, the objective of this narrative review of the literature was to identify the relationship between the colonization of the intestinal microbiota and the development of intestinal inflammatory pathologies, according to the literature published between 2003 and 2020.

• Fecha de publicación: 2022
• Institución: Pontificia Universidad Javeriana Cali
• Repositorio: Vitela
• Idioma: spa
• OAI Identifier: oai:vitela.javerianacali.edu.co:11522/430
• Acceso en línea: https://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/601; https://vitela.javerianacali.edu.co/handle/11522/430
• Palabra clave: Enfermedades inflamatorias del intestino; Colitis ulcerosa; Enfermedad de Crohn; Microbiota intestinal; Inflammatory bowel diseases; Colitis ulcerative; Crohn disease; Gastrointestinal microbiome
• License: Derechos de autor 2022 Salutem Scientia Spiritus