Chronic kidney disease: Cystatin C as a diagnostic marker.

Chronic kidney disease is a disease with high levels of morbidity and mortality; Currently, it is diagnosed with serum creatinine and estimating GFR, being the CKD-EPI and MDRD equations the most used. An extensive search of the literature was carried out in different databases to reveal aspects of...

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Fecha de publicación:: 2022

Institución:: Pontificia Universidad Javeriana Cali

Repositorio:: Vitela

Idioma:: spa

id	Vitela2_68cc8a713ab6691cfd6f2eaaa51daec3
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spelling	Lambis-Loaiza, Laura AlejandraRoldan-Tabares, Mabel DahianaMartínez-Sánchez, Lina María2022-09-302023-10-11T04:34:56Z2023-10-11T04:34:56Zhttps://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/645https://vitela.javerianacali.edu.co/handle/11522/451Chronic kidney disease is a disease with high levels of morbidity and mortality; Currently, it is diagnosed with serum creatinine and estimating GFR, being the CKD-EPI and MDRD equations the most used. An extensive search of the literature was carried out in different databases to reveal aspects of chronic kidney disease, its conventional diagnosis and new diagnostic methods. Measuring serum creatinine is not sufficient to assess kidney function, while cystatin C, by freely filtering through the kidney and not binding to plasma proteins, makes this the most accurate measure to estimate kidney function. There is still no precise marker to correctly assess the glomerular filtration rate, however, cystatin C is of great diagnostic utility for kidney failure, since its elevated levels identify a greater risk for kidney disease.La enfermedad renal crónica es una enfermedad con altos niveles de morbimortalidad; actualmente se diagnostica con la creatinina sérica y estimando la TFG, siendo las ecuaciones CKD-EPI y MDRD las más usadas. Se realizó́ una búsqueda extensa de la literatura en distintas bases de datos para dar a conocer aspectos sobre la enfermedad renal crónica, su diagnóstico convencional y nuevos métodos diagnósticos. El medir la creatinina en suero no es suficiente para evaluar la función renal, mientras que la cistatina C al filtrarse libremente por el riñón y al no unirse a proteínas plasmáticas hace de esta la medida más exacta para estimar la función renal. Aún no se cuenta con un marcador preciso para evaluar correctamente la tasa de filtración glomerular, sin embargo, la cistatina C es de gran utilidad diagnóstica para la insuficiencia renal, ya que sus niveles elevados identifican un mayor riesgo para enfermedad renal.application/pdfspaPontificia Universidad Javeriana Calihttps://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/645/548Derechos de autor 2023 Salutem Scientia Spiritushttps://creativecommons.org/licenses/by-nc-nd/4.0Salutem Scientia Spiritus; Vol. 8 No. 3 (2022): Revista Salutem Scientia Spiritus; 51-57Salutem Scientia Spiritus; Vol. 8 Núm. 3 (2022): Revista Salutem Scientia Spiritus; 51-572463-1426Tasa de filtración glomerularEnfermedades renalesFallo renal crónicoPruebas de función renalCistatina CGlomerular filtration rateKidney diseasesChronic kidney failureRenal function testsCysta-tin CChronic kidney disease: Cystatin C as a diagnostic marker.Enfermedad renal crónica: Cistatina C como marcador diagnóstico.info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRevisión de la literatura11522/451oai:vitela.javerianacali.edu.co:11522/4512024-06-25 05:12:42.419metadata.onlyhttps://vitela.javerianacali.edu.coRepositorio Vitelavitela.mail@javerianacali.edu.co
dc.title.en-US.fl_str_mv	Chronic kidney disease: Cystatin C as a diagnostic marker.
dc.title.es-ES.fl_str_mv	Enfermedad renal crónica: Cistatina C como marcador diagnóstico.
title	Chronic kidney disease: Cystatin C as a diagnostic marker.
spellingShingle	Chronic kidney disease: Cystatin C as a diagnostic marker. Lambis-Loaiza, Laura Alejandra Tasa de filtración glomerular Enfermedades renales Fallo renal crónico Pruebas de función renal Cistatina C Glomerular filtration rate Kidney diseases Chronic kidney failure Renal function tests Cysta-tin C
title_short	Chronic kidney disease: Cystatin C as a diagnostic marker.
title_full	Chronic kidney disease: Cystatin C as a diagnostic marker.
title_fullStr	Chronic kidney disease: Cystatin C as a diagnostic marker.
title_full_unstemmed	Chronic kidney disease: Cystatin C as a diagnostic marker.
title_sort	Chronic kidney disease: Cystatin C as a diagnostic marker.
dc.creator.none.fl_str_mv	Lambis-Loaiza, Laura Alejandra Roldan-Tabares, Mabel Dahiana Martínez-Sánchez, Lina María
author	Lambis-Loaiza, Laura Alejandra
author_facet	Lambis-Loaiza, Laura Alejandra Roldan-Tabares, Mabel Dahiana Martínez-Sánchez, Lina María
author_role	author
author2	Roldan-Tabares, Mabel Dahiana Martínez-Sánchez, Lina María
author2_role	author author
dc.subject.es-ES.fl_str_mv	Tasa de filtración glomerular Enfermedades renales Fallo renal crónico Pruebas de función renal Cistatina C
topic	Tasa de filtración glomerular Enfermedades renales Fallo renal crónico Pruebas de función renal Cistatina C Glomerular filtration rate Kidney diseases Chronic kidney failure Renal function tests Cysta-tin C
dc.subject.en-US.fl_str_mv	Glomerular filtration rate Kidney diseases Chronic kidney failure Renal function tests Cysta-tin C
description	Chronic kidney disease is a disease with high levels of morbidity and mortality; Currently, it is diagnosed with serum creatinine and estimating GFR, being the CKD-EPI and MDRD equations the most used. An extensive search of the literature was carried out in different databases to reveal aspects of chronic kidney disease, its conventional diagnosis and new diagnostic methods. Measuring serum creatinine is not sufficient to assess kidney function, while cystatin C, by freely filtering through the kidney and not binding to plasma proteins, makes this the most accurate measure to estimate kidney function. There is still no precise marker to correctly assess the glomerular filtration rate, however, cystatin C is of great diagnostic utility for kidney failure, since its elevated levels identify a greater risk for kidney disease.
publishDate	2022
dc.date.accessioned.none.fl_str_mv	2023-10-11T04:34:56Z
dc.date.available.none.fl_str_mv	2023-10-11T04:34:56Z
dc.date.none.fl_str_mv	2022-09-30
dc.type.none.fl_str_mv	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion
dc.type.es-ES.fl_str_mv	Revisión de la literatura
status_str	publishedVersion
dc.identifier.none.fl_str_mv	https://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/645
dc.identifier.uri.none.fl_str_mv	https://vitela.javerianacali.edu.co/handle/11522/451
url	https://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/645 https://vitela.javerianacali.edu.co/handle/11522/451
dc.language.none.fl_str_mv	spa
language	spa
dc.relation.none.fl_str_mv	https://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/645/548
dc.rights.es-ES.fl_str_mv	Derechos de autor 2023 Salutem Scientia Spiritus https://creativecommons.org/licenses/by-nc-nd/4.0
rights_invalid_str_mv	Derechos de autor 2023 Salutem Scientia Spiritus https://creativecommons.org/licenses/by-nc-nd/4.0
dc.format.none.fl_str_mv	application/pdf
dc.publisher.es-ES.fl_str_mv	Pontificia Universidad Javeriana Cali
dc.source.en-US.fl_str_mv	Salutem Scientia Spiritus; Vol. 8 No. 3 (2022): Revista Salutem Scientia Spiritus; 51-57
dc.source.es-ES.fl_str_mv	Salutem Scientia Spiritus; Vol. 8 Núm. 3 (2022): Revista Salutem Scientia Spiritus; 51-57
dc.source.none.fl_str_mv	2463-1426
institution	Pontificia Universidad Javeriana Cali
repository.name.fl_str_mv	Repositorio Vitela
repository.mail.fl_str_mv	vitela.mail@javerianacali.edu.co
_version_	1808493676123389952

Chronic kidney disease: Cystatin C as a diagnostic marker.

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