Chronic kidney disease: Cystatin C as a diagnostic marker.

Chronic kidney disease is a disease with high levels of morbidity and mortality; Currently, it is diagnosed with serum creatinine and estimating GFR, being the CKD-EPI and MDRD equations the most used. An extensive search of the literature was carried out in different databases to reveal aspects of...

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Autores:
Tipo de recurso:
Fecha de publicación:
2022
Institución:
Pontificia Universidad Javeriana Cali
Repositorio:
Vitela
Idioma:
spa
OAI Identifier:
oai:vitela.javerianacali.edu.co:11522/451
Acceso en línea:
https://revistas.javerianacali.edu.co/index.php/salutemscientiaspiritus/article/view/645
https://vitela.javerianacali.edu.co/handle/11522/451
Palabra clave:
Tasa de filtración glomerular
Enfermedades renales
Fallo renal crónico
Pruebas de función renal
Cistatina C
Glomerular filtration rate
Kidney diseases
Chronic kidney failure
Renal function tests
Cysta-tin C
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License
Derechos de autor 2023 Salutem Scientia Spiritus
Description
Summary:Chronic kidney disease is a disease with high levels of morbidity and mortality; Currently, it is diagnosed with serum creatinine and estimating GFR, being the CKD-EPI and MDRD equations the most used. An extensive search of the literature was carried out in different databases to reveal aspects of chronic kidney disease, its conventional diagnosis and new diagnostic methods. Measuring serum creatinine is not sufficient to assess kidney function, while cystatin C, by freely filtering through the kidney and not binding to plasma proteins, makes this the most accurate measure to estimate kidney function. There is still no precise marker to correctly assess the glomerular filtration rate, however, cystatin C is of great diagnostic utility for kidney failure, since its elevated levels identify a greater risk for kidney disease.