Las generaciones de las vacunas: Caso de vacunas antiparasitarias gastrointestinales utilizadas en Medicina Veterinaria
Las vacunas son el pilar fundamental de la medicina preventiva y la base para posibles planes de control y/o erradicación de enfermedades, especialmente las infecciosas. Los parásitos internos en los animales de producción y de compañía continúan siendo una de las principales amenazas para la salud...
- Autores:
-
Prieto Prieto, Laura Daniela
Vargas Borda , Lina Maria
Jaramillo Hernández, Dumar Alexander
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2021
- Institución:
- Universidad de los Llanos
- Repositorio:
- Repositorio Digital Universidad de los LLanos
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unillanos.edu.co:001/4367
- Acceso en línea:
- https://repositorio.unillanos.edu.co/handle/001/4367
https://doi.org/10.22579/22484817.879
- Palabra clave:
- Internal parasite management
public health
zoonose
Manejo integrado de parásitos internos
salud pública
zoonosis
Manejo integrado de parasitas internos
saúde pública
zoonose
- Rights
- openAccess
- License
- Revista Sistemas de Producción Agroecológicos - 2021
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dc.title.spa.fl_str_mv |
Las generaciones de las vacunas: Caso de vacunas antiparasitarias gastrointestinales utilizadas en Medicina Veterinaria |
dc.title.translated.eng.fl_str_mv |
The generations of the vaccines: Case of gastrointestinal antiparasitic vaccines used in Veterinary Medicine |
title |
Las generaciones de las vacunas: Caso de vacunas antiparasitarias gastrointestinales utilizadas en Medicina Veterinaria |
spellingShingle |
Las generaciones de las vacunas: Caso de vacunas antiparasitarias gastrointestinales utilizadas en Medicina Veterinaria Internal parasite management public health zoonose Manejo integrado de parásitos internos salud pública zoonosis Manejo integrado de parasitas internos saúde pública zoonose |
title_short |
Las generaciones de las vacunas: Caso de vacunas antiparasitarias gastrointestinales utilizadas en Medicina Veterinaria |
title_full |
Las generaciones de las vacunas: Caso de vacunas antiparasitarias gastrointestinales utilizadas en Medicina Veterinaria |
title_fullStr |
Las generaciones de las vacunas: Caso de vacunas antiparasitarias gastrointestinales utilizadas en Medicina Veterinaria |
title_full_unstemmed |
Las generaciones de las vacunas: Caso de vacunas antiparasitarias gastrointestinales utilizadas en Medicina Veterinaria |
title_sort |
Las generaciones de las vacunas: Caso de vacunas antiparasitarias gastrointestinales utilizadas en Medicina Veterinaria |
dc.creator.fl_str_mv |
Prieto Prieto, Laura Daniela Vargas Borda , Lina Maria Jaramillo Hernández, Dumar Alexander |
dc.contributor.author.spa.fl_str_mv |
Prieto Prieto, Laura Daniela Vargas Borda , Lina Maria |
dc.contributor.author.none.fl_str_mv |
Jaramillo Hernández, Dumar Alexander |
dc.subject.eng.fl_str_mv |
Internal parasite management public health zoonose |
topic |
Internal parasite management public health zoonose Manejo integrado de parásitos internos salud pública zoonosis Manejo integrado de parasitas internos saúde pública zoonose |
dc.subject.spa.fl_str_mv |
Manejo integrado de parásitos internos salud pública zoonosis Manejo integrado de parasitas internos saúde pública zoonose |
description |
Las vacunas son el pilar fundamental de la medicina preventiva y la base para posibles planes de control y/o erradicación de enfermedades, especialmente las infecciosas. Los parásitos internos en los animales de producción y de compañía continúan siendo una de las principales amenazas para la salud y el bienestar animal con importantes implicaciones económicas, además de su impacto en la salud pública mundial. Su control se ha basado casi exclusivamente en fármacos quimioterápicos, que desde hace varios años han perdido su eficacia y existen claros ejemplos de resistencia parasitaria a ellos. Hay pocos ejemplos comerciales de vacunas de parásitos gastrointestinales disponibles comercialmente para su uso en la práctica de la Medicina Veterinaria. Esta revisión describe algunos ejemplos comerciales de vacunas gastrointestinales antiparasitarias para su formulación en la práctica médica veterinaria, visto desde la perspectiva de “las generaciones de vacunas” y respaldado por estudios clínicos experimentales de antígenos prometedores para el control profiláctico de ciertos agentes parasitarios gastrointestinales de interés en salud pública principalmente. Hasta la fecha, está disponible con ciertas limitaciones comerciales en algunos países europeos y oceánicos Barbervax® y en países sudamericanos Providean® Hidatil EG95 para uso en rumiantes para el control de Haemonchus contortus y Echinococcus granulosus, respectivamente; en algunos países de América y África, Cysvax™ está disponible para el control de Taenia solium en cerdos; y en el mundo con muy pocas limitaciones, una serie de vacunas comerciales para el control de la coccidosis como la Eimeria spp. en la industria avícola: pavos, pollos de engorde y gallinas ponedoras (ej: CocciVac®, Immucox®, Paracox®, entre otros). Existe la necesidad de tener estos tipos de vacunas en todos los países donde estos parásitos gastrointestinales son endémicos y de esta manera brindar opciones para su control, por consiguiente, una serie de inversiones económicas son necesarias para apoyar el desarrollo técnico-científico en torno al desarrollo de nuevos biológicos (nueva generaciones de vacunas) efectivos y seguros para el control de los parásitos internos más relevantes en animales de producción y de compañía. |
publishDate |
2021 |
dc.date.accessioned.none.fl_str_mv |
2021-12-15T00:00:00Z 2024-09-23T20:46:38Z |
dc.date.available.none.fl_str_mv |
2021-12-15T00:00:00Z 2024-09-23T20:46:38Z |
dc.date.issued.none.fl_str_mv |
2021-12-15 |
dc.type.spa.fl_str_mv |
Artículo de revista |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.local.eng.fl_str_mv |
Journal article |
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info:eu-repo/semantics/publishedVersion |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
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Text |
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dc.identifier.uri.none.fl_str_mv |
https://repositorio.unillanos.edu.co/handle/001/4367 |
dc.identifier.doi.none.fl_str_mv |
10.22579/22484817.879 |
dc.identifier.eissn.none.fl_str_mv |
2248-4817 |
dc.identifier.url.none.fl_str_mv |
https://doi.org/10.22579/22484817.879 |
url |
https://repositorio.unillanos.edu.co/handle/001/4367 https://doi.org/10.22579/22484817.879 |
identifier_str_mv |
10.22579/22484817.879 2248-4817 |
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dc.relation.references.spa.fl_str_mv |
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Salazar F, Santiago F, Santos S, Jaramillo A, da Silva B, Alves V, Silveira F, Barrouin M, Cooper J, Pacheco L, Pinheiro C, Alcantara M. Immunogenicity and protection induced by recombinant Toxocara canis proteins in a murine model of toxocariasis. Vaccine, 2020;38(30):4762–4772. Seib L, Zhao X, Rappuoli R. Developing vaccines in the era of genomics: a decade of reverse vaccinology. Clinical microbiology and infection: the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2012;18(5):109–116. Siefker C, Rickard G. Vaccination of calves with Haemonchus placei intestinal homogenate. Veterinary parasitology, 2000;88(3-4),249–260. Song H, Yan R, Xu L, Song X, Shah A, Zhu H, Li X. Efficacy of DNA vaccines carrying Eimeria acervulina lactate dehydrogenase antigen gene against coccidiosis. Experimental parasitology, 2010;126(2), 224–231. Song X, Xu L, Yan R, Huang X, Shah A, Li X. The optimal immunization procedure of DNA vaccine pcDNA-TA4-IL-2 of Eimeria tenella and its cross-immunity to Eimeria necatrix and Eimeria acervulina. Veterinary parasitology, 2009;159(1):30–36. Sun C, Beilke N, Lanier L. Adaptive immune features of natural killer cells. Nature, 2009;457(7229):557–561. Swiderski E, Klei R, Folsom W, Pourciau S, Chapman A, Chapman R, Moore M, McClure R, Taylor W, Horohov W. Vaccination against Strongylus vulgaris in ponies: comparison of the humoral and cytokine responses of vaccinates and nonvaccinates. Advances in veterinary medicine, 1999;41:389–404. Tyagi R, Joachim A, Ruttkowski B, Rosa A, Martin C, Hallsworth K, Zhang X, Ozersky P, Wilson K, Ranganathan S, Sternberg W, Gasser B, Mitreva M. Cracking the nodule worm code advances knowledge of parasite biology and biotechnology to tackle major diseases of livestock. Biotechnology advances, 2015;33(6Pt1):980–991. Unnikrishnan M, Rappuoli R, Serruto D. Recombinant bacterial vaccines. Current opinion in immunology, 2012;24(3):337–342. Vargas M, Prieto D, Baquero M, Corredor W, Alcantara M, Jaramillo D. Vaccines for gastrointestinal parasites, a pillar of preventive medicine in veterinary practice: Systematic review. Revista de Investigación Agraria y Ambiental, 2022;13(1): 221-251. Versteeg L, Almutairi M, Hotez J, Pollet J. Enlisting the mRNA Vaccine Platform to Combat Parasitic Infections. Vaccines, 2019;7(4),122. Vetter V, Denizer G, Friedland R, Krishnan J, Shapiro M. Understanding modern-day vaccines: what you need to know. Annals of medicine, 2018;50(2):110–120. Vlaminck J, Martinez M, Dewilde S, Moens L, Tilleman K, Deforce D, Urban J, Claerebout E, Vercruysse J, Geldhof P. Immunizing pigs with Ascaris suum haemoglobin increases the inflammatory response in the liver but fails to induce a protective immunity. Parasite immunology,2011;33(4):250–254. Wallach M, Smith C, Petracca M, Miller M, Eckert J, Braun R. Eimeria maxima gametocyte antigens: potential use in a subunit maternal vaccine against coccidiosis in chickens. Vaccine, 1995;13(4):347–354. Wedrychowicz H. Antiparasitic DNA vaccines in 21st century. Acta Parasitologica, 2015;60(2):179-189. World Health Organization (WHO), Echinococcosis fact sheet, Disponible en: https://www.who.int/news-room/fact-sheets/detail/echinococcosis.2020. Xu J, Zhang Y, Tao J. Efficacy of a DNA vaccine carrying Eimeria maxima Gam56 antigen gene against coccidiosis in chickens. The Korean journal of parasitology, 2013;51(2):147–154. Zhang W, Zhang Z, Shi B, Li J, You H, Tulson G, Dang X, Song Y, Yimiti T, Wang J, Jones K, McManus P. Vaccination of dogs against Echinococcus granulosus, the cause of cystic hydatid disease in humans. The Journal of infectious diseases, 2006;194(7):966–974. |
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Prieto Prieto, Laura DanielaVargas Borda , Lina MariaJaramillo Hernández, Dumar Alexandervirtual::145-12021-12-15T00:00:00Z2024-09-23T20:46:38Z2021-12-15T00:00:00Z2024-09-23T20:46:38Z2021-12-15https://repositorio.unillanos.edu.co/handle/001/436710.22579/22484817.8792248-4817https://doi.org/10.22579/22484817.879Las vacunas son el pilar fundamental de la medicina preventiva y la base para posibles planes de control y/o erradicación de enfermedades, especialmente las infecciosas. Los parásitos internos en los animales de producción y de compañía continúan siendo una de las principales amenazas para la salud y el bienestar animal con importantes implicaciones económicas, además de su impacto en la salud pública mundial. Su control se ha basado casi exclusivamente en fármacos quimioterápicos, que desde hace varios años han perdido su eficacia y existen claros ejemplos de resistencia parasitaria a ellos. Hay pocos ejemplos comerciales de vacunas de parásitos gastrointestinales disponibles comercialmente para su uso en la práctica de la Medicina Veterinaria. Esta revisión describe algunos ejemplos comerciales de vacunas gastrointestinales antiparasitarias para su formulación en la práctica médica veterinaria, visto desde la perspectiva de “las generaciones de vacunas” y respaldado por estudios clínicos experimentales de antígenos prometedores para el control profiláctico de ciertos agentes parasitarios gastrointestinales de interés en salud pública principalmente. Hasta la fecha, está disponible con ciertas limitaciones comerciales en algunos países europeos y oceánicos Barbervax® y en países sudamericanos Providean® Hidatil EG95 para uso en rumiantes para el control de Haemonchus contortus y Echinococcus granulosus, respectivamente; en algunos países de América y África, Cysvax™ está disponible para el control de Taenia solium en cerdos; y en el mundo con muy pocas limitaciones, una serie de vacunas comerciales para el control de la coccidosis como la Eimeria spp. en la industria avícola: pavos, pollos de engorde y gallinas ponedoras (ej: CocciVac®, Immucox®, Paracox®, entre otros). Existe la necesidad de tener estos tipos de vacunas en todos los países donde estos parásitos gastrointestinales son endémicos y de esta manera brindar opciones para su control, por consiguiente, una serie de inversiones económicas son necesarias para apoyar el desarrollo técnico-científico en torno al desarrollo de nuevos biológicos (nueva generaciones de vacunas) efectivos y seguros para el control de los parásitos internos más relevantes en animales de producción y de compañía.Vaccines are the fundamental pillar of preventive medicine and the basis for possible control and/or eradication of disease plans, especially infectious diseases. Internal parasites in production and companion animals continue to be one of the main threats to animal health and welfare with important economic implications, in addition to its impact on global public health. Its control has been based almost exclusively on chemotherapeutic drugs, which for several years have lost their efficacy and there are clear examples of parasitic resistance to them. Even so, few commercial examples of gastrointestinal parasite vaccines are commercially available for use in the practice of Veterinary Medicine. This review describes some commercial examples of gastrointestinal antiparasitic vaccines for their formulation in veterinary medical practice seen from the perspective of “the generations of vaccines'' and supported by experimental clinical studies of promising antigens for the prophylactic control of certain gastrointestinal parasitic agents of interest in public health mainly. To date, it is available with certain commercial limitations in some European and Australian countries Barbervax® and in South American countries Providean® Hidatil EG95 for use in ruminants for the control of Haemonchus contortus and Echinococcus granulosus, respectively; in some countries in America and Africa, Cysvax™ is available for the control of Taenia solium in pigs and in the world with very few limitations, a series of commercial vaccines for the control of coccidosis (Eimeria spp.) in poultry industry: turkeys, broilers and laying hens (e.g., CocciVac®, Immucox®, Paracox®, among others). There is a need to provide this type of vaccine to all countries where these gastrointestinal parasites are endemic and, in this way, provide options for their control. As well as a series of economic investments is highly necessary to support technical-scientific development around development of new effective and safe biologicals (new generations of vaccines) for the control of the most relevant internal parasites in production and companion animals.application/pdfspaUniversidad de los LlanosRevista Sistemas de Producción Agroecológicos - 2021https://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2https://revistas.unillanos.edu.co/index.php/sistemasagroecologicos/article/view/879Internal parasite managementpublic healthzoonoseManejo integrado de parásitos internossalud públicazoonosisManejo integrado de parasitas internossaúde públicazoonoseLas generaciones de las vacunas: Caso de vacunas antiparasitarias gastrointestinales utilizadas en Medicina VeterinariaThe generations of the vaccines: Case of gastrointestinal antiparasitic vaccines used in Veterinary MedicineArtículo de revistainfo:eu-repo/semantics/articleJournal articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Texthttp://purl.org/redcol/resource_type/ARTREFhttp://purl.org/coar/version/c_970fb48d4fbd8a85Babu S, Nutman T. 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The Journal of infectious diseases, 2006;194(7):966–974.https://revistas.unillanos.edu.co/index.php/sistemasagroecologicos/article/download/879/945Núm. 2 , Año 2021 : Julio-Diciembre9627412Revista Sistemas de Producción AgroecológicosPublication3e90075e-e6d7-4a60-9623-0d169fda1eaevirtual::145-13e90075e-e6d7-4a60-9623-0d169fda1eaevirtual::145-1https://scholar.google.com/citations?user=ugMx8ecAAAAJ&hl=esvirtual::145-10000-0003-1377-1747virtual::145-1https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0000633925virtual::145-1OREORE.xmltext/xml2768https://repositorio.unillanos.edu.co/bitstreams/b7a9467f-98ef-4b52-8998-f76a3e82eb7b/downloadcf3e8bc6ffe9cec6ce19553d45fe04b4MD51001/4367oai:repositorio.unillanos.edu.co:001/43672024-10-04 16:21:41.438https://creativecommons.org/licenses/by-nc-sa/4.0/Revista Sistemas de Producción Agroecológicos - 2021metadata.onlyhttps://repositorio.unillanos.edu.coRepositorio Universidad de Los Llanosrepositorio@unillanos.edu.co |