Generalidades del tumor de células de la granulosa en yeguas
Existen diferentes patologías ováricas que disminuyen la capacidad reproductiva de las yeguas donde los procesos neoplásicos o tumores en el ovario en la hembra equina son muy frecuentes; siendo el tumor de células de la granulosa (TCG) el de mayor presentación correspondiendo al 2,5% de todas las n...
- Autores:
-
Chinchilla Silva, Erika Nathaly
Jaramillo Hernández, Dumar Alexander
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2022
- Institución:
- Universidad de los Llanos
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- Repositorio Digital Universidad de los LLanos
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- spa
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- oai:repositorio.unillanos.edu.co:001/4370
- Acceso en línea:
- https://repositorio.unillanos.edu.co/handle/001/4370
https://doi.org/10.22579/22484817.882
- Palabra clave:
- animal pathology
equine reproduction
ovariectomy
ovariectomía
patología animal
reproducción equina
ovariectomia
patologia animal
reprodução equina
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- openAccess
- License
- Revista Sistemas de Producción Agroecológicos - 2022
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| dc.title.spa.fl_str_mv |
Generalidades del tumor de células de la granulosa en yeguas |
| dc.title.translated.eng.fl_str_mv |
Generalities of granulose cell tumor in mares |
| title |
Generalidades del tumor de células de la granulosa en yeguas |
| spellingShingle |
Generalidades del tumor de células de la granulosa en yeguas animal pathology equine reproduction ovariectomy ovariectomía patología animal reproducción equina ovariectomia patologia animal reprodução equina |
| title_short |
Generalidades del tumor de células de la granulosa en yeguas |
| title_full |
Generalidades del tumor de células de la granulosa en yeguas |
| title_fullStr |
Generalidades del tumor de células de la granulosa en yeguas |
| title_full_unstemmed |
Generalidades del tumor de células de la granulosa en yeguas |
| title_sort |
Generalidades del tumor de células de la granulosa en yeguas |
| dc.creator.fl_str_mv |
Chinchilla Silva, Erika Nathaly Jaramillo Hernández, Dumar Alexander |
| dc.contributor.author.spa.fl_str_mv |
Chinchilla Silva, Erika Nathaly |
| dc.contributor.author.none.fl_str_mv |
Jaramillo Hernández, Dumar Alexander |
| dc.subject.eng.fl_str_mv |
animal pathology equine reproduction ovariectomy |
| topic |
animal pathology equine reproduction ovariectomy ovariectomía patología animal reproducción equina ovariectomia patologia animal reprodução equina |
| dc.subject.spa.fl_str_mv |
ovariectomía patología animal reproducción equina ovariectomia patologia animal reprodução equina |
| description |
Existen diferentes patologías ováricas que disminuyen la capacidad reproductiva de las yeguas donde los procesos neoplásicos o tumores en el ovario en la hembra equina son muy frecuentes; siendo el tumor de células de la granulosa (TCG) el de mayor presentación correspondiendo al 2,5% de todas las neoplasias presentes en equinos. El TCG representa un problema económico en los criaderos de alto valor genético debido al tiempo reproductivo perdido en la yegua, los altos costos de diagnóstico, tratamientos y en ciertas ocasiones la necesidad de descartar una hembra reproductora. Debido a su alta incidencia en la industria equina del país y el mundo es importante contar con información fisiopatológica actualizada que permita tomar decisiones terapéuticas basadas en la evidencia científica. El objetivo de este artículo fue hacer una revisión sistemática sobre TCG en yeguas. Para eso se realizó búsqueda de información en diversas bases de datos, utilizando palabras de búsqueda como: tumor de células de la granulosa en yeguas, granulosa cell tumors in mares, patologías ováricas en yeguas y fisiopatología del tumor de células de la granulosa, ovarian pathologies in mares and physiopathology of granulose cell tumor. Finalmente, el presente trabajo concluye que la fisiopatología de TCG en yeguas sigue sin ser esclarecida debido a los múltiples factores que pueden estar involucrados; y su diagnóstico depende de la asociación de las manifestaciones clínicas, examen ultrasonográfico, los resultados del perfil hormonal e histopatología. |
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2022 |
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2022-06-30T00:00:00Z 2024-09-23T20:46:39Z |
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2022-06-30T00:00:00Z 2024-09-23T20:46:39Z |
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2022-06-30 |
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Artículo de revista |
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2248-4817 |
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Ali A, Al-Sobayill A, Tharwat M, Mehana E, & Al-Hawas A. Granulosa cell tumour in a female dromedary camel. Comparative Clinical Pathology, 2013;22(6):1251–1254. https://doi.org/10.1007/s00580-013-1755-z Ali A, Alamaary M, Al-Sobayill F, Mehana E, & Fathy A. Ovarian tumours in Arabian mares. Comparative Clinical Pathology, 2015;24(1):157–162. https://doi.org/10.1007/s00580-013-1877-3 Almeida J., Ball A., Conley A. J., Place N. J., Liu I. K. M., Scholtz E. L., Mathewson L., Stanley S. D., Moeller B. C. Biological and clinical significance of anti-Müllerian hormone determination in blood serum of the mare. Theriogenology, 2011;76(8):1393–1403. Disponible en: https://doi.org/10.1016/j.theriogenology.2011.06.008 Amrozi A., Melia J., Parwati L., Tumbelaka L. I. T. A. Prevalence of Mares’ Granulosa Theca Cell Tumor (Gtct) in Indonesia. Jurnal Kedokteran Hewan - Indonesian Journal of Veterinary Sciences, 2020;13(4):98–100. https://doi.org/10.21157/j.ked.hewan.v13i4.12797 Amrozi A., Soehartono R., Adistya E., Mahardi I., Mukarromah H., SATRIA M. I., WAI, H. RAVI S. Removal of granulosa theca cells tumor in the mare. ARSHI Veterinary Letters, 2020;4(1):11-12. https://doi.org/10.29244/avl.4.1.11-12 Ball B. A., Almeida J., Conley A. J. Determination of serum anti-Müllerian hormone concentrations for the diagnosis of granulosa-cell tumours in mares. Equine Veterinary Journal, 2013;45(2):199-203. https://doi.org/10.1111/j.2042-3306.2012.00594.x Boerboom D, Paquet M, Hsieh M, Liu J, Jamin S. P, Behringer R. R, Sirois J., Taketo M. M, Richards J. A. S. Misregulated Wnt/β-catenin signaling to ovarian granulosa cell tumor development. Cancer Research, 2005;65(20):9206-9215. https://doi.org/10.1158/0008-5472.CAN-05-1024 Castillo J, Tse M. P, Dockweiler J, Cheong S, Amorim M. D. Case Report Rapport de cas Bilateral granulosa cell tumor in a cycling mare. 2019. 60(May). Chavarria Rivera, J. Patologías ováricas en equinos (Equus ferus caballus) de alto valor genético en ranchos de criadores de los departamentos de Managua, Masaya y Chinandega en el periodo Julio 2012- Julio 2013. Conley A. J, Scholtz E. L, Dujovne G, Cotterman R. F, Legacki E. L, Uliani R. C, Alvarenga M. A, Ball B. A, Karla B, Savjani G. V, Kumar A. Inhibin-A and inhibin-B in cyclic and pregnant mares, and mares with granulosa-theca cell tumors: Physiological and diagnostic implications. Theriogenology, 2018;108:192-200. https://doi.org/10.1016/j.theriogenology.2017.12.003 Cortés Z, Aréchiga C, Rincón M, Rochín F, López M, Flores G. Revisión: El Ciclo Reproductivo de la Yegua. Abanico Veterinario, 2018;8(3):14-41. https://doi.org/10.21929/abavet2018.83.1 Crabtree J. Papers Review of seven cases of granulosa cell tumour of the equine ovary. 2011. https://doi.org/10.1136/vr.d4635 Crabtree J. Can ovariectomy be justified on grounds of behaviour ? Vet Times. 2014. https://www.vettimes.co.uk Crabtree J. R, Brennan M. J, Foote A. K, Pycock J. F. Granulosa cell tumour: An interesting case in a pregnant mare. Equine Veterinary Education, 2013;25(1):4-10. https://doi.org/10.1111/j.2042-3292.2011.00361.x De Macedo G C, Pereira N. N, Gomes W. T, De Andrade G. B, Miraglia H, Vilela Campos J. B. Tumor de células da granulosa em égua: relato de caso granulosa cell tumor. EBSCOhost. Archives of Veterinary Science. 2016. Disponible en: http://webebsco.unillanos.elogim.com/ehost/detail/detail?vid=9&sid=9b1ffa9a-3bc5-4357-88b4-4e914654aa0f%40sdc-v-sessmgr03&bdata=Jmxhbmc9ZXMmc2l0ZT1laG9zdC1saXZl#db=asn&AN=119801367 Ellenberger C, Bartmann C. P, Hoppen H. O, Kratzsch J, Aupperle H, Klug E, Schoon D, Schoon, H. A. Histomorphological and immunohistochemical characterization of equine granulosa cell tumours. Journal of Comparative Pathology, 2007;136(2-3):167-176. https://doi.org/10.1016/j.jcpa.2007.01.011 Franco J, Uribe Velásquez, L. F. Reproductive hormones of veterinary importance in domestic ruminant females. Biosalud. 2012. http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S1657-95502012000100006&lng=en&nrm=iso&tlng=es Frederico L M, Gerard M P, Pinto C R F, Gradil C M. Bilateral occurrence of granulosa-theca cell tumors in an Arabian mare. Canadian Veterinary Journal, 2007;48(5):502-505. Gharagozlou F, Youssefi R, Akbarinejad V, Ashrafihelan J. Elevated serum anti-müllerian hormone in an arabian mare with granulosa cell tumor. Journal of Equine Veterinary Science, 2013;33(8):645-648. https://doi.org/10.1016/j.jevs.2012.09.003 Gharagozlou F, Youssefi R, Akbarinejad V, Masoudifard M, Ashrafihelan J. Changes of serum anti-Müllerian hormone in a mare with granulosa cell tumour following surgery and reinitiation of follicular activity. Equine Veterinary Education, 2014;26(9):481-484. https://doi.org/10.1111/eve.12170 Gündüz M, Kaşikçi G, Kiliçarslan R, Uçmak M, Düzgün O, Tek Ç. Reproductive performance following unilateral ovariectomy for treatment of ovarian tumors in 7 mares. Turkish Journal Of Veterinary And Animal Sciences, 2010;34(3):283–287. https://doi.org/10.3906/vet-0812-20 Hendrickson, D. A. A. Review of Equine Laparoscopy. ISRN Veterinary Science, 2012,1-17. https://doi.org/10.5402/2012/492650 Hoque M, Derar R, Tsunoda N, Senba H, Osawa T, Miyake Y. Clinical findings before and after the removal of ovaries affected with granulosa theca cell tumor (GTCT) in 16 mares. Journal of Equine Science, 2002;13(3):75-81. https://doi.org/10.1294/jes.13.75 Hughes, L. (n.d.). Granulosa Cell Tumors in the Mare. Retrieved May 11, 2021, from www.newenglandequine.com Hyatt J, Hanlon D, Hollinshead F. Anti-Müllerian Hormone - a new test for the diagnosis of Granulosa Cell Tumours in mares. CVE Control & Therapy Series, 2015;279:9-10. Kim SInsights into granulosa cell tumors using spontaneous or genetically engineered mouse models. 2016;43(1):1-8. Korany M. S, Derbala K, Mosallam E, Fadel M, Aly H, Essmail M. E Diagnosis of granulosa cell tumors in arabian mares by ultrasonography, hormonal profile and histopathology. Advances in Animal and Veterinary Sciences, 2020;8(3):327-332. https://doi.org/10.17582/journal.aavs/2020/8.3.327.332 Liebig E, Davis A, Klohonatz M, Graham E, Hendrickson A, Easley T, Hackett S, Pinedo J, Eckery C, Bruemmer E. Circulating and Cultured Anti-Müllerian Hormone Concentrations Following Hemi-ovariectomy in Anestrous Mares. Journal of Equine Veterinary Science,2018;66:118. https://doi.org/10.1016/j.jevs.2018.05.163 Maclachlan N. J, Kennedy P. C. Tumors of the Genital Systems. In Tumors in Domestic Animals, Lowa State Press, 2008;547-573. https://doi.org/10.1002/9780470376928.ch11 Maurice K. T. Diagnosis and surgical removal of a granulosa-theca cell tumor in a mare. 2005;46(July):0-2. Mccue P, Roser J, Munro C, Liu I K, Lasley B. Granulosa Cell Tumors of the Equine Ovary. 2006;22:799-817. https://doi.org/10.1016/j.cveq.2006.08.008 32. Mccue, P. M. (2013). Granulosa Cell Tumor in a Mare. 3;1-7. Melgaard D, Korsgaard T, Thoefner M, Petersen M, Pedersen H. Moody mares—Is ovariectomy a solution? Animals, 2020;10(7):1-11. https://doi.org/10.3390/ani10071210 Miguez S, Bizarro Da Silva C, Zandonadi F, Romero G, Silva K. Marcondes M. Granulosa cells tumor in mules. Revista Acadêmica Ciência Animal, 2015;13(0). https://doi.org/10.7213/academica.13.fc.ao09 Mihm M, Bleach E. C. L. Endocrine regulation of ovarian antral follicle development in cattle. Animal Reproduction Science, 2003;78(3-4):217-237. https://doi.org/10.1016/S0378-4320(03)00092-7 Moher D, Liberai A, Tetzlaff J, Altman D. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. In BMJ (Online) British Medical Journal Publishing Group. 2009;339(7716):332-336. https://doi.org/10.1136/bmj.b2535 Mora V, Fuentes E, Góngora A. Diagnóstico y tratamiento de un tumor de células de la granulosa en una yegua criolla colombiana. Redalyc.Org, 2004;8(2):42-48. http://www.redalyc.org/articulo.oa?id=89680204 Moya C F, Carmo M T, Merlini G P, Araujo G H M. Perfil hormonal de égua com tumor das células da granulosa-teca. In Inovação e Pluralidade na Medicina Veterinária, Atena Editora. 2020;3:86-91. https://doi.org/10.22533/at.ed.84520110812 Müller K, Ellenberger C, Hoppen H O, Schoon H A. Immunohistochemical study of angiogenesis and angiogenic factors in equine granulosa cell tumours. Research in Veterinary Science, 2012;92(3):471-477. https://doi.org/10.1016/j.rvsc.2011.02.016 Munkhtuul T, Murase H, Ball B, Habukawa K, Sato F, Watanabe K, Nambo Y. Immunolocalization of anti-Müllerian Hormone and Its Receptor in Granulosa Cell Tumors in Mares. Journal of Equine Veterinary Science, 2019;74:9-12. https://doi.org/10.1016/j.jevs.2018.12.012 Murase H, Ball B, Tangyuenyong S, Watanabe G, Sato F, Hada T, Nambo Y. Serum Anti-Müllerian Hormone Concentrations in Mares With Granulosa Cell Tumors Versus Other Ovarian Abnormalities. Journal of Equine Veterinary Science, 2018;60:6-10. https://doi.org/10.1016/j.jevs.2017.10.012 Patrick D, Kiupel M, Gerber V, Carr E. Malignant granulosa-theca cell tumor in a two-year-old miniature horse. Journal of Veterinary Diagnostic Investigation, 2003;15(1):60-63. https://doi.org/10.1177/104063870301500114 Petrizzi L, Guerri G, Straticò P, Cuomo A, Vullo C, De Amicis I, Robbe D, Varasano V. Laparoscopic Ovariectomy in Standing Mule Mares. Journal of Equine Veterinary Science, 2020;84. https://doi.org/10.1016/j.jevs.2019.102857 Pinna A, Okada C, Ferreira C, Campos R, Possidente K, Morais R, Oliveira M, Salomão M, Hataka A. Double ovarian tumour in the mare: Case report. Reproduction in Domestic Animals, 2019;54(6):912–916. https://doi.org/10.1111/rda.13433 Prestes N, Nogueira De Moraes C, Maia L, De Oliveira I, Sousa Fabris V, Alvarenga M. Ovarian Tumor in a Mare-Thecoma-Case Report. Journal of Equine Veterinary Science, 2013;33(3):196–200. https://doi.org/10.1016/j.jevs.2012.06.007 Renaudin C, Kelleman A, Keel K, Mccracken J, Ball B, Ferris R, Mccue P, Dujovne G, Conley A. Equine granulosa cell tumours among other ovarian conditions : Diagnostic challenges. 2020:1–11. https://doi.org/10.1111/evj.13279 Röcken M, Mosel G, Seyrek K, Seyrek D., Litzke F, Verver J, Rijkenhuizen A. Unilateral and Bilateral Laparoscopic Ovariectomy in 157 Mares: A Retrospective Multicenter Study. Veterinary Surgery, 2011;40(8):1009–1014. https://doi.org/10.1111/j.1532-950X.2011.00884.x Ruiz A, Rivera C, Calderon C, Franco A, Gomez D. Tumor de células de la granulosa: diagnóstico, tratamiento hormonal e intervención quirúrgica en yegua criolla colombiana. Revista Colombiana de Ciencia Animal - RECIA, 2013;5(2):527. https://doi.org/10.24188/recia.v5.n2.2013.462 Sherlock C, Lott K, Bergren A, Withers J, Fews D, Mair T. Granulosa cell tumours in the mare : A review of 52 cases. 2016;28:75-82. https://doi.org/10.1111/eve.12449 Smith L. Moody mares – ovariectomy in the horse. Veterinary Nursing Journal, 2012;27(3),109-111. https://doi.org/10.1111/j.2045-0648.2011.00115.x Troedsson H, Mccue P, Macpherson L. Clinical aspects of ovarian pathology in the mare. Pferdeheilkunde, 2003;19(6):577-584 Trundelll D. Abnormalities of the mare’s ovaries. Livestock, 2017;22(5):278-281. https://doi.org/10.12968/live.2017.22.5.278 Vanderwall D, Rood K. How to Use Anti-Müllerian Hormone Testing to Diagnose Granulosa Cell Tumors in Mares. 2014:1-6. Zelli R, Sylla L, Monaci M, Stradaioli G, Sibley L, Roser J, Munro C, Liu M. Gonadotropin secretion and pituitary responsiveness to GnRH in mares with granulosa-theca cell tumor.Theriogenology,2006;66(5):1210-1218. https://doi.org/10.1016/j.theriogenology.2006.03.030 |
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Chinchilla Silva, Erika NathalyJaramillo Hernández, Dumar Alexandervirtual::146-12022-06-30T00:00:00Z2024-09-23T20:46:39Z2022-06-30T00:00:00Z2024-09-23T20:46:39Z2022-06-30https://repositorio.unillanos.edu.co/handle/001/437010.22579/22484817.8822248-4817https://doi.org/10.22579/22484817.882Existen diferentes patologías ováricas que disminuyen la capacidad reproductiva de las yeguas donde los procesos neoplásicos o tumores en el ovario en la hembra equina son muy frecuentes; siendo el tumor de células de la granulosa (TCG) el de mayor presentación correspondiendo al 2,5% de todas las neoplasias presentes en equinos. El TCG representa un problema económico en los criaderos de alto valor genético debido al tiempo reproductivo perdido en la yegua, los altos costos de diagnóstico, tratamientos y en ciertas ocasiones la necesidad de descartar una hembra reproductora. Debido a su alta incidencia en la industria equina del país y el mundo es importante contar con información fisiopatológica actualizada que permita tomar decisiones terapéuticas basadas en la evidencia científica. El objetivo de este artículo fue hacer una revisión sistemática sobre TCG en yeguas. Para eso se realizó búsqueda de información en diversas bases de datos, utilizando palabras de búsqueda como: tumor de células de la granulosa en yeguas, granulosa cell tumors in mares, patologías ováricas en yeguas y fisiopatología del tumor de células de la granulosa, ovarian pathologies in mares and physiopathology of granulose cell tumor. Finalmente, el presente trabajo concluye que la fisiopatología de TCG en yeguas sigue sin ser esclarecida debido a los múltiples factores que pueden estar involucrados; y su diagnóstico depende de la asociación de las manifestaciones clínicas, examen ultrasonográfico, los resultados del perfil hormonal e histopatología.There are different ovarian pathologies that decrease the reproductive capacity of mares where neoplastic processes or tumors in the ovary in the equine female are very frequent; being the granulosa cell tumor (TCG) the one with the greatest presentation corresponding to 2,5% of all neoplasms present in horses. The (TCG) represents an economic problem in breeders of high genetic value due to the reproductive time lost in the mare, the high costs of diagnosis, treatments and sometimes the need to discard a breeding female. Due to its high impact on the equine industry of the country and the world it is important to have up-to-date physiopathology information to make therapeutic decisions based on scientific evidence. The objective of this article was to make a systematic review on TCG in mares. For this, information was searched in various databases, using search words such as: tumor de células de la granulosa en yeguas, granulosa cell tumors in mares, patologías ováricas en yeguas y fisiopatología del tumor de células de la granulosa, ovarian pathologies in mares and physiopathology of granulose cell tumor. Finally, this work concludes that the physiopathology of TCG in mares remains unclared due to the multiple factors that may be involved and that its diagnosis depends on the association of clinical manifestations, ultrasonographic examination, hormonal profile results and histopatology.application/pdfspaUniversidad de los LlanosRevista Sistemas de Producción Agroecológicos - 2022https://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2https://revistas.unillanos.edu.co/index.php/sistemasagroecologicos/article/view/882animal pathologyequine reproductionovariectomyovariectomíapatología animalreproducción equinaovariectomiapatologia animalreprodução equinaGeneralidades del tumor de células de la granulosa en yeguasGeneralities of granulose cell tumor in maresArtículo de revistainfo:eu-repo/semantics/articleJournal articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Texthttp://purl.org/redcol/resource_type/ARTREFhttp://purl.org/coar/version/c_970fb48d4fbd8a85Ali A, Al-Sobayill A, Tharwat M, Mehana E, & Al-Hawas A. 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Gonadotropin secretion and pituitary responsiveness to GnRH in mares with granulosa-theca cell tumor.Theriogenology,2006;66(5):1210-1218. https://doi.org/10.1016/j.theriogenology.2006.03.030https://revistas.unillanos.edu.co/index.php/sistemasagroecologicos/article/download/882/948Núm. 1 , Año 2022 : Enero-Junio141213Revista Sistemas de Producción AgroecológicosPublication3e90075e-e6d7-4a60-9623-0d169fda1eaevirtual::146-13e90075e-e6d7-4a60-9623-0d169fda1eaevirtual::146-1https://scholar.google.com/citations?user=ugMx8ecAAAAJ&hl=esvirtual::146-10000-0003-1377-1747virtual::146-1https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0000633925virtual::146-1OREORE.xmltext/xml2597https://repositorio.unillanos.edu.co/bitstreams/b2c060df-f05a-46db-b633-74c5801a7e3d/download144ec70a154603d5a4d923dcb25dcf22MD51001/4370oai:repositorio.unillanos.edu.co:001/43702024-10-04 16:23:05.826https://creativecommons.org/licenses/by-nc-sa/4.0/Revista Sistemas de Producción Agroecológicos - 2022metadata.onlyhttps://repositorio.unillanos.edu.coRepositorio Universidad de Los Llanosrepositorio@unillanos.edu.co |