Alternativas no quirúrgicas de esterilización en animales de abasto: Una revisión de literatura
La esterilización de animales domésticos se realiza por diferentes motivos. En algunos casos, para lograr mansedumbre y facilitar el manejo, y en otros casos para mejorar el marmoleo de la carne ya que animales castrados producen más grasa que animales sin castrar. Existe una corriente beneficiosa a...
- Autores:
-
Suárez Giraldo, Valeria
Zapata Mejía , Carolina
- Tipo de recurso:
- Bibliografía
- Fecha de publicación:
- 2022
- Institución:
- Universidad Tecnológica de Pereira
- Repositorio:
- Repositorio Institucional UTP
- Idioma:
- OAI Identifier:
- oai:repositorio.utp.edu.co:11059/14107
- Acceso en línea:
- https://hdl.handle.net/11059/14107
- Palabra clave:
- 630 - Agricultura y tecnologías relacionadas::636 - Producción animal
Esterilización animal - Alternativas
Animal - Abasto
Ganaderia-productividad
Bienestar animal
Alternativa de castración
Emasculación
- Rights
- openAccess
- License
- Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
| id |
UTP2_153c964fa081ccd72b650fddb8701374 |
|---|---|
| oai_identifier_str |
oai:repositorio.utp.edu.co:11059/14107 |
| network_acronym_str |
UTP2 |
| network_name_str |
Repositorio Institucional UTP |
| repository_id_str |
|
| dc.title.spa.fl_str_mv |
Alternativas no quirúrgicas de esterilización en animales de abasto: Una revisión de literatura |
| title |
Alternativas no quirúrgicas de esterilización en animales de abasto: Una revisión de literatura |
| spellingShingle |
Alternativas no quirúrgicas de esterilización en animales de abasto: Una revisión de literatura 630 - Agricultura y tecnologías relacionadas::636 - Producción animal Esterilización animal - Alternativas Animal - Abasto Ganaderia-productividad Bienestar animal Alternativa de castración Emasculación |
| title_short |
Alternativas no quirúrgicas de esterilización en animales de abasto: Una revisión de literatura |
| title_full |
Alternativas no quirúrgicas de esterilización en animales de abasto: Una revisión de literatura |
| title_fullStr |
Alternativas no quirúrgicas de esterilización en animales de abasto: Una revisión de literatura |
| title_full_unstemmed |
Alternativas no quirúrgicas de esterilización en animales de abasto: Una revisión de literatura |
| title_sort |
Alternativas no quirúrgicas de esterilización en animales de abasto: Una revisión de literatura |
| dc.creator.fl_str_mv |
Suárez Giraldo, Valeria Zapata Mejía , Carolina |
| dc.contributor.advisor.none.fl_str_mv |
Echeverry López , Juan Carlos |
| dc.contributor.author.none.fl_str_mv |
Suárez Giraldo, Valeria Zapata Mejía , Carolina |
| dc.subject.ddc.none.fl_str_mv |
630 - Agricultura y tecnologías relacionadas::636 - Producción animal |
| topic |
630 - Agricultura y tecnologías relacionadas::636 - Producción animal Esterilización animal - Alternativas Animal - Abasto Ganaderia-productividad Bienestar animal Alternativa de castración Emasculación |
| dc.subject.agrovocuri.none.fl_str_mv |
Esterilización animal - Alternativas Animal - Abasto Ganaderia-productividad |
| dc.subject.proposal.spa.fl_str_mv |
Bienestar animal Alternativa de castración Emasculación |
| description |
La esterilización de animales domésticos se realiza por diferentes motivos. En algunos casos, para lograr mansedumbre y facilitar el manejo, y en otros casos para mejorar el marmoleo de la carne ya que animales castrados producen más grasa que animales sin castrar. Existe una corriente beneficiosa a nivel mundial con respecto al bienestar animal. Cada vez existe más presión para que los animales que dan alimento a la humanidad no sufran de dolor. Desafortunadamente, la técnica de castración se realiza más comúnmente sin el uso de anestesia. La inmunocastración es una técnica que utiliza un antagonista de la GnRH que bloquea la producción hormonal a nivel de las gónadas. La especie donde se utiliza de forma rutinaria es la porcina. Se maneja un protocolo de dos inyecciones donde la segunda se aplica de cuatro a cinco semanas antes del sacrificio. Las otras especies también se pueden inmunocastrar, pero los productos no se comercializan fácilmente y su uso en bovinos necesita más estudios debido a ser un animal de ciclo largo. Se tuvo en cuenta solo información del 2015 hasta la fecha. |
| publishDate |
2022 |
| dc.date.accessioned.none.fl_str_mv |
2022-05-17T19:14:25Z |
| dc.date.available.none.fl_str_mv |
2022-05-17T19:14:25Z |
| dc.date.issued.none.fl_str_mv |
2022 |
| dc.type.none.fl_str_mv |
Trabajo de grado - Pregrado |
| dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_8042 |
| dc.type.version.none.fl_str_mv |
info:eu-repo/semantics/acceptedVersion |
| dc.type.coar.none.fl_str_mv |
http://purl.org/coar/resource_type/c_86bc |
| dc.type.content.none.fl_str_mv |
Text |
| dc.type.driver.none.fl_str_mv |
info:eu-repo/semantics/workingPaper |
| format |
http://purl.org/coar/resource_type/c_86bc |
| status_str |
acceptedVersion |
| dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/11059/14107 |
| url |
https://hdl.handle.net/11059/14107 |
| dc.relation.references.none.fl_str_mv |
Masłowska K, Mizzoni F, Dwyer CM, Wemelsfelder F. Qualitative behavioural assessment of pain in castrated lambs. Appl Anim Behav Sci. 2020;233(June). Hempstead MN, Lindquist TM, Shearer JK, Shearer LC, Sutherland MA, Plummer PJ. Acute cortisol and behavior of dairy goat kids administered local anesthesia, topical anesthesia or systemic analgesia prior to cautery disbudding. Physiol Behav [Internet]. 2020;222(April):112942. Available from: https://doi.org/10.1016/j.physbeh.2020.112942 Connor M, Cowan SL. Consumer evaluation of farm animal mutilations. Res Vet Sci [Internet]. 2019;128:35–42. Available from: https://doi.org/10.1016/j.rvsc.2019.10.006 Park SJ, Piao M, Kim H, Kang HJ, Seo J, Lee S, et al. Effects of castration and a lidocaine-plus-flunixin treatment on growth and indicators of pain, inflammation, and liver function in Korean cattle bull calves. Livest Sci [Internet]. 2018;216:61–6. Available from: https://doi.org/10.1016/j.livsci.2018.07.010 Radford KD, Berman RY, Zhang M, Wu TJ, Choi KH. Sex-related differences in intravenous ketamine effects on dissociative stereotypy and antinociception in male and female rats. Pharmacol Biochem Behav [Internet]. 2020;199(September):173042. Available from: https://doi.org/10.1016/j.pbb.2020.173042 Marcantonio Coneglian M, Duarte Borges T, Weber SH, Godoi Bertagnon H, Michelotto PV. Use of the horse grimace scale to identify and quantify pain due to dental disorders in horses. Appl Anim Behav Sci [Internet]. 2020;225(February):104970. Available from: https://doi.org/10.1016/j.applanim.2020.104970 Chapa JM, Maschat K, Iwersen M, Baumgartner J, Drillich M. Accelerometer systems as tools for health and welfare assessment in cattle and pigs – A review. Behav Processes [Internet]. 2020;181(June):104262. Available from: https://doi.org/10.1016/j.beproc.2020.104262 Terán E. Aproximaciones Al Estudio Del Dolor En Los Animales No Humanos. 2018;(1). Scollo A, Minervini S, Galli MC, Cevidalli A, Bortoletto G, Romano G, et al. Evaluation of pain and stress in three-week old piglets in relation to route of vaccine administration. Livest Sci [Internet]. 2020;233:103939. Available from: https://doi.org/10.1016/j.livsci.2020.103939 González-Cano R, Montilla-García Á, Ruiz-Cantero MC, Bravo-Caparrós I, Tejada M, Nieto FR, et al. The search for translational pain outcomes to refine analgesic development: Where did we come from and where are we going? Neurosci Biobehav Rev [Internet]. 2020;113(March):238–61. Available from: https://doi.org/10.1016/j.neubiorev.2020.03.004 Caffarena RD, Riet-correa F, Giannitti F. Uso de prácticas de manejo del dolor durante el desbotonamiento y descorne de las terneras de tambo: un estudio piloto en Uruguay y Argentina. Vet. 2018;54(210):22–6. Andrighetto Canozzi ME, Rossi Borges JA, Jardim Barcellos JO. Attitudes of cattle veterinarians and animal scientists to pain and painful procedures in Brazil. Prev Vet Med [Internet]. 2020;177(August):104909. Available from: https://doi.org/10.1016/j.prevetmed.2020.104909 Park SJ, Piao M, Kim H, Kang HJ, Fassah DM, Jung DJS, et al. Effects of dehorning and lidocaine-plus-flunixin treatment on indicators of stress and acute inflammation, behaviors, and their association in Korean cattle bull calves. Livest Sci [Internet]. 2020;241(August):104198. Available from: https://doi.org/10.1016/j.livsci.2020.104198 Grela ER, Świątkiewicz M, Kowalczuk-Vasilev E, Florek M, Kosior Korzecka U, Skałecki P. An attempt of implementation of immunocastration in swine production – impact on meat physicochemical quality and boar taint compound concentration in the meat of two native pig breeds. Livest Sci. 2020;232. Zeng F mei, Ding Y, Wassie T, Jing H jing, Ahmed S, Liu G qiong, et al. Recent advances in immunocastration in sheep and goat and its animal welfare benefits: A review. J Integr Agric [Internet]. 2022;21(2):299–309. Available from: http://dx.doi.org/10.1016/S2095-3119(21)63670-5 Dalla Costa OA, Tavernari F de C, Lopes L dos S, Dalla Costa FA, Feddern V, de Lima GJMM. Performance, carcass and meat quality of pigs submitted to immunocastration and different feeding programs. Res Vet Sci [Internet]. 2020;131(April):137–45. Available from: https://doi.org/10.1016/j.rvsc.2020.04.015 Hakansson F, Houe H. Risk factors associated with tail damage in conventional non-docked pigs throughout the lactation and rearing period. Prev Vet Med [Internet]. 2020;184(June):105160. Available from: https://doi.org/10.1016/j.prevetmed.2020.105160 Pierozan CR, Callegari MA, Dias CP, De Souza KL, Gasa J, Da Silva CA. Herd-level factors associated with piglet weight at weaning, kilograms of piglets weaned per sow per year and sow feed conversion. Animal [Internet]. 2020;14(6):1283–92. Available from: http://dx.doi.org/10.1017/S175173111900346X Tomasevic I, Bahelka I, Čandek-Potokar M, Čítek J, Djekić I, Djurkin Kušec I, et al. Attitudes and beliefs of Eastern European consumers towards piglet castration and meat from castrated pigs. Meat Sci [Internet]. 2020;160:107965. Available from: https://doi.org/10.1016/j.meatsci.2019.107965 Seiquer I, Palma-Granados P, Haro A, Lara L, Lachica M, Fernández Fígares I, et al. Meat quality traits in longissimus lumborum and gluteus medius muscles from immunocastrated and surgically castrated Iberian pigs. Meat Sci [Internet]. 2019;150:77–84. Available from: https://doi.org/10.1016/j.meatsci.2018.12.004 Monleón E, Noya A, Carmen Garza M, Ripoll G, Sanz A. Effects of an anti-gonadotrophin releasing hormone vaccine on the morphology, structure and function of bull testes. Theriogenology. 2020;141:211–8 Brigida DJ, Antonelo DS, Mazon MR, Nubiato KEZ, Gómez JFM, Netto AS, et al. Effects of immunocastration and a β-adrenergic agonist on retail cuts of feedlot finished Nellore cattle. Animal [Internet]. 2018;12(8):1690– 5. Available from: http://dx.doi.org/10.1017/S1751731117003317 Mazon MR, Antonelo DS, Gómez JFM, Nubiato KEZ, Balage JM, Silva HB, et al. Effects of combining immunocastration and β-adrenergic agonists on the meat quality of Nellore cattle. Livest Sci [Internet]. 2019;226:13–20. Available from: https://doi.org/10.1016/j.livsci.2019.05.015 Andreo N, Bridi AM, Soares AL, Prohmann PEF, Peres LM, Tarsitano MA, et al. Fatty acid profile of beef from immunocastrated (BOPRIVA®) Nellore bulls. Meat Sci [Internet]. 2016;117:12–7. Available from: http://dx.doi.org/10.1016/j.meatsci.2016.02.029 Lents MP, Barbosa LP, Santana ALA, Pinheiro EEG, Mugabe LC, Biscarde CEA, et al. Immunocastration of goats using anti-gonadotrophin releasing hormone vaccine. Theriogenology. 2018;114:7–13. Kells NJ, Beausoleil NJ, R Godfrey AJ, E Littlewood K, Ward RN, Johnson CB. Effect of analgesic strategies on pain behaviour associated with combined ring castration and hot iron tail docking in Merino lambs. Appl Anim Behav Sci [Internet]. 2020;222:104914. Available from: https://doi.org/10.1016/j.applanim.2019.104914 Aponte PM, Gutierrez-Reinoso MA, Sanchez-Cepeda EG, Garcia Herreros M. Active immunization against GnRH in pre-pubertal domestic mammals: Testicular morphometry, histopathology and endocrine responses in rabbits, Guinea pigs and ram lambs. Animal [Internet]. 2018;12(4):784–93. Available from: http://dx.doi.org/10.1017/S1751731117002129 Wassie T, Zeng F, Jiang X, Liu G, Kasimu H, Ling S, et al. Effect of Kisspeptin-54 immunization on performance, carcass characteristics, meat quality and safety of Yiling goats. Meat Sci [Internet]. 2020;166(April):108139. Available from: https://doi.org/10.1016/j.meatsci.2020.108139 Small AH, Jongman EC, Niemeyer D, Lee C, Colditz IG. Efficacy of precisely injected single local bolus of lignocaine for alleviation of behavioural responses to pain during tail docking and castration of lambs with rubber rings. Res Vet Sci [Internet]. 2020;133(February):210–8. Available from: https://doi.org/10.1016/j.rvsc.2020.09.025 Needham T, Kotrba R, Hoffman LC, Bureš D. Ante-and post-mortem strategies to improve the meat quality of high-value muscles harvested from farmed male common eland (Taurotragus oryx). Meat Sci. 2020;168(February). Yao Z, Si W, Tian W, Ye J, Zhu R, Li X, et al. Effect of active immunization using a novel GnRH vaccine on reproductive function in rats. Theriogenology [Internet]. 2018;111:1–8. Available from: https://doi.org/10.1016/j.theriogenology.2018.01.013 Schaut RG, Brewer MT, Hostetter JM, Mendoza K, Vela-Ramirez JE, Kelly SM, et al. A single dose polyanhydride-based vaccine platform promotes and maintains anti-GnRH antibody titers. Vaccine [Internet]. 2018;36(7):1016–23. Available from: https://doi.org/10.1016/j.vaccine.2017.12.050 Han Y, Peng X, Li K, Jiang X, Liu G, Yang L, et al. Potent effect of KISS1- 54 DNA vaccine compared with KISS1-10 DNA vaccine in inhibiting the fertility of female rats. Vaccine [Internet]. 2018;36(45):6631–9. Available from: https://doi.org/10.1016/j.vaccine.2018.09.053 |
| dc.rights.license.none.fl_str_mv |
Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0) |
| dc.rights.uri.none.fl_str_mv |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| dc.rights.coar.none.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
| dc.rights.accessrights.none.fl_str_mv |
info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0) https://creativecommons.org/licenses/by-nc-nd/4.0/ http://purl.org/coar/access_right/c_abf2 |
| eu_rights_str_mv |
openAccess |
| dc.format.extent.none.fl_str_mv |
13 Páginas |
| dc.format.mimetype.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Universidad Tecnológica de Pereira |
| dc.publisher.program.none.fl_str_mv |
Medicina Veterinaria y Zootecnia |
| dc.publisher.faculty.none.fl_str_mv |
Facultad de Ciencias de la Salud |
| dc.publisher.place.none.fl_str_mv |
Pereira |
| publisher.none.fl_str_mv |
Universidad Tecnológica de Pereira |
| institution |
Universidad Tecnológica de Pereira |
| bitstream.url.fl_str_mv |
https://dspace7-utp.metabuscador.org/bitstreams/9bb4cac8-b7af-474d-8eff-8d1678a3b4ad/download https://dspace7-utp.metabuscador.org/bitstreams/0cd5ce6a-50a1-492a-929b-effc9a3f7f73/download https://dspace7-utp.metabuscador.org/bitstreams/2a7a48df-54fd-44f8-b965-56b73180a7f9/download https://dspace7-utp.metabuscador.org/bitstreams/f58db5c6-d1a7-4333-840f-6af1cd06a78b/download |
| bitstream.checksum.fl_str_mv |
60e3f974ee3bab43ceb8c020d0280cc0 2f9959eaf5b71fae44bbf9ec84150c7a 6b37b42abea006f4470b68f7b529a60a 89e5fa996b6df8110963188ddb4c7c47 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositorio de la Universidad Tecnológica de Pereira |
| repository.mail.fl_str_mv |
bdigital@metabiblioteca.com |
| _version_ |
1814021951771901952 |
| spelling |
Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)Manifiesto (Manifestamos) en este documento la voluntad de autorizar a la Biblioteca Jorge Roa Martínez de la Universidad Tecnológica de Pereira la publicación en el Repositorio institucional (http://biblioteca.utp.edu.co), la versión electrónica de la OBRA titulada: ________________________________________________________________________________________________ ________________________________________________________________________________________________ ________________________________________________________________________________________________ La Universidad Tecnológica de Pereira, entidad académica sin ánimo de lucro, queda por lo tanto facultada para ejercer plenamente la autorización anteriormente descrita en su actividad ordinaria de investigación, docencia y publicación. La autorización otorgada se ajusta a lo que establece la Ley 23 de 1982. Con todo, en mi (nuestra) condición de autor (es) me (nos) reservo (reservamos) los derechos morales de la OBRA antes citada con arreglo al artículo 30 dehttps://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessEcheverry López , Juan CarlosSuárez Giraldo, ValeriaZapata Mejía , Carolina2022-05-17T19:14:25Z2022-05-17T19:14:25Z2022https://hdl.handle.net/11059/14107La esterilización de animales domésticos se realiza por diferentes motivos. En algunos casos, para lograr mansedumbre y facilitar el manejo, y en otros casos para mejorar el marmoleo de la carne ya que animales castrados producen más grasa que animales sin castrar. Existe una corriente beneficiosa a nivel mundial con respecto al bienestar animal. Cada vez existe más presión para que los animales que dan alimento a la humanidad no sufran de dolor. Desafortunadamente, la técnica de castración se realiza más comúnmente sin el uso de anestesia. La inmunocastración es una técnica que utiliza un antagonista de la GnRH que bloquea la producción hormonal a nivel de las gónadas. La especie donde se utiliza de forma rutinaria es la porcina. Se maneja un protocolo de dos inyecciones donde la segunda se aplica de cuatro a cinco semanas antes del sacrificio. Las otras especies también se pueden inmunocastrar, pero los productos no se comercializan fácilmente y su uso en bovinos necesita más estudios debido a ser un animal de ciclo largo. Se tuvo en cuenta solo información del 2015 hasta la fecha.PregradoMédico(a) Veterinario(a) y Zootecnista13 Páginasapplication/pdfUniversidad Tecnológica de PereiraMedicina Veterinaria y ZootecniaFacultad de Ciencias de la SaludPereira630 - Agricultura y tecnologías relacionadas::636 - Producción animalEsterilización animal - AlternativasAnimal - AbastoGanaderia-productividadBienestar animalAlternativa de castraciónEmasculaciónAlternativas no quirúrgicas de esterilización en animales de abasto: Una revisión de literaturaTrabajo de grado - Pregradoinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_86bchttp://purl.org/coar/resource_type/c_8042Textinfo:eu-repo/semantics/workingPaperMasłowska K, Mizzoni F, Dwyer CM, Wemelsfelder F. Qualitative behavioural assessment of pain in castrated lambs. Appl Anim Behav Sci. 2020;233(June).Hempstead MN, Lindquist TM, Shearer JK, Shearer LC, Sutherland MA, Plummer PJ. Acute cortisol and behavior of dairy goat kids administered local anesthesia, topical anesthesia or systemic analgesia prior to cautery disbudding. Physiol Behav [Internet]. 2020;222(April):112942. Available from: https://doi.org/10.1016/j.physbeh.2020.112942Connor M, Cowan SL. Consumer evaluation of farm animal mutilations. Res Vet Sci [Internet]. 2019;128:35–42. Available from: https://doi.org/10.1016/j.rvsc.2019.10.006Park SJ, Piao M, Kim H, Kang HJ, Seo J, Lee S, et al. Effects of castration and a lidocaine-plus-flunixin treatment on growth and indicators of pain, inflammation, and liver function in Korean cattle bull calves. Livest Sci [Internet]. 2018;216:61–6. Available from: https://doi.org/10.1016/j.livsci.2018.07.010Radford KD, Berman RY, Zhang M, Wu TJ, Choi KH. Sex-related differences in intravenous ketamine effects on dissociative stereotypy and antinociception in male and female rats. Pharmacol Biochem Behav [Internet]. 2020;199(September):173042. Available from: https://doi.org/10.1016/j.pbb.2020.173042Marcantonio Coneglian M, Duarte Borges T, Weber SH, Godoi Bertagnon H, Michelotto PV. Use of the horse grimace scale to identify and quantify pain due to dental disorders in horses. Appl Anim Behav Sci [Internet]. 2020;225(February):104970. Available from: https://doi.org/10.1016/j.applanim.2020.104970Chapa JM, Maschat K, Iwersen M, Baumgartner J, Drillich M. Accelerometer systems as tools for health and welfare assessment in cattle and pigs – A review. Behav Processes [Internet]. 2020;181(June):104262. Available from: https://doi.org/10.1016/j.beproc.2020.104262Terán E. Aproximaciones Al Estudio Del Dolor En Los Animales No Humanos. 2018;(1).Scollo A, Minervini S, Galli MC, Cevidalli A, Bortoletto G, Romano G, et al. Evaluation of pain and stress in three-week old piglets in relation to route of vaccine administration. Livest Sci [Internet]. 2020;233:103939. Available from: https://doi.org/10.1016/j.livsci.2020.103939González-Cano R, Montilla-García Á, Ruiz-Cantero MC, Bravo-Caparrós I, Tejada M, Nieto FR, et al. The search for translational pain outcomes to refine analgesic development: Where did we come from and where are we going? Neurosci Biobehav Rev [Internet]. 2020;113(March):238–61. Available from: https://doi.org/10.1016/j.neubiorev.2020.03.004Caffarena RD, Riet-correa F, Giannitti F. Uso de prácticas de manejo del dolor durante el desbotonamiento y descorne de las terneras de tambo: un estudio piloto en Uruguay y Argentina. Vet. 2018;54(210):22–6.Andrighetto Canozzi ME, Rossi Borges JA, Jardim Barcellos JO. Attitudes of cattle veterinarians and animal scientists to pain and painful procedures in Brazil. Prev Vet Med [Internet]. 2020;177(August):104909. Available from: https://doi.org/10.1016/j.prevetmed.2020.104909Park SJ, Piao M, Kim H, Kang HJ, Fassah DM, Jung DJS, et al. Effects of dehorning and lidocaine-plus-flunixin treatment on indicators of stress and acute inflammation, behaviors, and their association in Korean cattle bull calves. Livest Sci [Internet]. 2020;241(August):104198. Available from: https://doi.org/10.1016/j.livsci.2020.104198Grela ER, Świątkiewicz M, Kowalczuk-Vasilev E, Florek M, Kosior Korzecka U, Skałecki P. An attempt of implementation of immunocastration in swine production – impact on meat physicochemical quality and boar taint compound concentration in the meat of two native pig breeds. Livest Sci. 2020;232.Zeng F mei, Ding Y, Wassie T, Jing H jing, Ahmed S, Liu G qiong, et al. Recent advances in immunocastration in sheep and goat and its animal welfare benefits: A review. J Integr Agric [Internet]. 2022;21(2):299–309. Available from: http://dx.doi.org/10.1016/S2095-3119(21)63670-5Dalla Costa OA, Tavernari F de C, Lopes L dos S, Dalla Costa FA, Feddern V, de Lima GJMM. Performance, carcass and meat quality of pigs submitted to immunocastration and different feeding programs. Res Vet Sci [Internet]. 2020;131(April):137–45. Available from: https://doi.org/10.1016/j.rvsc.2020.04.015Hakansson F, Houe H. Risk factors associated with tail damage in conventional non-docked pigs throughout the lactation and rearing period. Prev Vet Med [Internet]. 2020;184(June):105160. Available from: https://doi.org/10.1016/j.prevetmed.2020.105160Pierozan CR, Callegari MA, Dias CP, De Souza KL, Gasa J, Da Silva CA. Herd-level factors associated with piglet weight at weaning, kilograms of piglets weaned per sow per year and sow feed conversion. Animal [Internet]. 2020;14(6):1283–92. Available from: http://dx.doi.org/10.1017/S175173111900346XTomasevic I, Bahelka I, Čandek-Potokar M, Čítek J, Djekić I, Djurkin Kušec I, et al. Attitudes and beliefs of Eastern European consumers towards piglet castration and meat from castrated pigs. Meat Sci [Internet]. 2020;160:107965. Available from: https://doi.org/10.1016/j.meatsci.2019.107965Seiquer I, Palma-Granados P, Haro A, Lara L, Lachica M, Fernández Fígares I, et al. Meat quality traits in longissimus lumborum and gluteus medius muscles from immunocastrated and surgically castrated Iberian pigs. Meat Sci [Internet]. 2019;150:77–84. Available from: https://doi.org/10.1016/j.meatsci.2018.12.004Monleón E, Noya A, Carmen Garza M, Ripoll G, Sanz A. Effects of an anti-gonadotrophin releasing hormone vaccine on the morphology, structure and function of bull testes. Theriogenology. 2020;141:211–8Brigida DJ, Antonelo DS, Mazon MR, Nubiato KEZ, Gómez JFM, Netto AS, et al. Effects of immunocastration and a β-adrenergic agonist on retail cuts of feedlot finished Nellore cattle. Animal [Internet]. 2018;12(8):1690– 5. Available from: http://dx.doi.org/10.1017/S1751731117003317Mazon MR, Antonelo DS, Gómez JFM, Nubiato KEZ, Balage JM, Silva HB, et al. Effects of combining immunocastration and β-adrenergic agonists on the meat quality of Nellore cattle. Livest Sci [Internet]. 2019;226:13–20. Available from: https://doi.org/10.1016/j.livsci.2019.05.015Andreo N, Bridi AM, Soares AL, Prohmann PEF, Peres LM, Tarsitano MA, et al. Fatty acid profile of beef from immunocastrated (BOPRIVA®) Nellore bulls. Meat Sci [Internet]. 2016;117:12–7. Available from: http://dx.doi.org/10.1016/j.meatsci.2016.02.029Lents MP, Barbosa LP, Santana ALA, Pinheiro EEG, Mugabe LC, Biscarde CEA, et al. Immunocastration of goats using anti-gonadotrophin releasing hormone vaccine. Theriogenology. 2018;114:7–13.Kells NJ, Beausoleil NJ, R Godfrey AJ, E Littlewood K, Ward RN, Johnson CB. Effect of analgesic strategies on pain behaviour associated with combined ring castration and hot iron tail docking in Merino lambs. Appl Anim Behav Sci [Internet]. 2020;222:104914. Available from: https://doi.org/10.1016/j.applanim.2019.104914Aponte PM, Gutierrez-Reinoso MA, Sanchez-Cepeda EG, Garcia Herreros M. Active immunization against GnRH in pre-pubertal domestic mammals: Testicular morphometry, histopathology and endocrine responses in rabbits, Guinea pigs and ram lambs. Animal [Internet]. 2018;12(4):784–93. Available from: http://dx.doi.org/10.1017/S1751731117002129Wassie T, Zeng F, Jiang X, Liu G, Kasimu H, Ling S, et al. Effect of Kisspeptin-54 immunization on performance, carcass characteristics, meat quality and safety of Yiling goats. Meat Sci [Internet]. 2020;166(April):108139. Available from: https://doi.org/10.1016/j.meatsci.2020.108139Small AH, Jongman EC, Niemeyer D, Lee C, Colditz IG. Efficacy of precisely injected single local bolus of lignocaine for alleviation of behavioural responses to pain during tail docking and castration of lambs with rubber rings. Res Vet Sci [Internet]. 2020;133(February):210–8. Available from: https://doi.org/10.1016/j.rvsc.2020.09.025Needham T, Kotrba R, Hoffman LC, Bureš D. Ante-and post-mortem strategies to improve the meat quality of high-value muscles harvested from farmed male common eland (Taurotragus oryx). Meat Sci. 2020;168(February).Yao Z, Si W, Tian W, Ye J, Zhu R, Li X, et al. Effect of active immunization using a novel GnRH vaccine on reproductive function in rats. Theriogenology [Internet]. 2018;111:1–8. Available from: https://doi.org/10.1016/j.theriogenology.2018.01.013Schaut RG, Brewer MT, Hostetter JM, Mendoza K, Vela-Ramirez JE, Kelly SM, et al. A single dose polyanhydride-based vaccine platform promotes and maintains anti-GnRH antibody titers. Vaccine [Internet]. 2018;36(7):1016–23. Available from: https://doi.org/10.1016/j.vaccine.2017.12.050Han Y, Peng X, Li K, Jiang X, Liu G, Yang L, et al. Potent effect of KISS1- 54 DNA vaccine compared with KISS1-10 DNA vaccine in inhibiting the fertility of female rats. Vaccine [Internet]. 2018;36(45):6631–9. Available from: https://doi.org/10.1016/j.vaccine.2018.09.053PublicationORIGINALTRABAJO DE GRADO.pdfTRABAJO DE GRADO.pdfapplication/pdf91682https://dspace7-utp.metabuscador.org/bitstreams/9bb4cac8-b7af-474d-8eff-8d1678a3b4ad/download60e3f974ee3bab43ceb8c020d0280cc0MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-814828https://dspace7-utp.metabuscador.org/bitstreams/0cd5ce6a-50a1-492a-929b-effc9a3f7f73/download2f9959eaf5b71fae44bbf9ec84150c7aMD52TEXTTRABAJO DE GRADO.pdf.txtTRABAJO DE GRADO.pdf.txtExtracted texttext/plain26942https://dspace7-utp.metabuscador.org/bitstreams/2a7a48df-54fd-44f8-b965-56b73180a7f9/download6b37b42abea006f4470b68f7b529a60aMD53THUMBNAILTRABAJO DE GRADO.pdf.jpgTRABAJO DE GRADO.pdf.jpgGenerated Thumbnailimage/jpeg13562https://dspace7-utp.metabuscador.org/bitstreams/f58db5c6-d1a7-4333-840f-6af1cd06a78b/download89e5fa996b6df8110963188ddb4c7c47MD5411059/14107oai:dspace7-utp.metabuscador.org:11059/141072024-09-05 17:08:20.988https://creativecommons.org/licenses/by-nc-nd/4.0/Manifiesto (Manifestamos) en este documento la voluntad de autorizar a la Biblioteca Jorge Roa Martínez de la Universidad Tecnológica de Pereira la publicación en el Repositorio institucional (http://biblioteca.utp.edu.co), la versión electrónica de la OBRA titulada: ________________________________________________________________________________________________ ________________________________________________________________________________________________ ________________________________________________________________________________________________ La Universidad Tecnológica de Pereira, entidad académica sin ánimo de lucro, queda por lo tanto facultada para ejercer plenamente la autorización anteriormente descrita en su actividad ordinaria de investigación, docencia y publicación. La autorización otorgada se ajusta a lo que establece la Ley 23 de 1982. Con todo, en mi (nuestra) condición de autor (es) me (nos) reservo (reservamos) los derechos morales de la OBRA antes citada con arreglo al artículo 30 deopen.accesshttps://dspace7-utp.metabuscador.orgRepositorio de la Universidad Tecnológica de Pereirabdigital@metabiblioteca.comTEEgT0JSQSAoVEFMIFkgQ09NTyBTRSBERUZJTkUgTcOBUyBBREVMQU5URSkgU0UgT1RPUkdBIEJBSk8gTE9TIFRFUk1JTk9TIERFIEVTVEEgTElDRU5DSUEgUMOaQkxJQ0EgREUgQ1JFQVRJVkUgQ09NTU9OUyAo4oCcTFBDQ+KAnSBPIOKAnExJQ0VOQ0lB4oCdKS4gTEEgT0JSQSBFU1TDgSBQUk9URUdJREEgUE9SIERFUkVDSE9TIERFIEFVVE9SIFkvVSBPVFJBUyBMRVlFUyBBUExJQ0FCTEVTLiBRVUVEQSBQUk9ISUJJRE8gQ1VBTFFVSUVSIFVTTyBRVUUgU0UgSEFHQSBERSBMQSBPQlJBIFFVRSBOTyBDVUVOVEUgQ09OIExBIEFVVE9SSVpBQ0nDk04gUEVSVElORU5URSBERSBDT05GT1JNSURBRCBDT04gTE9TIFTDiVJNSU5PUyBERSBFU1RBIExJQ0VOQ0lBIFkgREUgTEEgTEVZIERFIERFUkVDSE8gREUgQVVUT1IuCgpNRURJQU5URSBFTCBFSkVSQ0lDSU8gREUgQ1VBTFFVSUVSQSBERSBMT1MgREVSRUNIT1MgUVVFIFNFIE9UT1JHQU4gRU4gRVNUQSBMSUNFTkNJQSwgVVNURUQgQUNFUFRBIFkgQUNVRVJEQSBRVUVEQVIgT0JMSUdBRE8gRU4gTE9TIFRFUk1JTk9TIFFVRSBTRSBTRcORQUxBTiBFTiBFTExBLiBFTCBMSUNFTkNJQU5URSBDT05DRURFIEEgVVNURUQgTE9TIERFUkVDSE9TIENPTlRFTklET1MgRU4gRVNUQSBMSUNFTkNJQSBDT05ESUNJT05BRE9TIEEgTEEgQUNFUFRBQ0nDk04gREUgU1VTIFRFUk1JTk9TIFkgQ09ORElDSU9ORVMuCjEuIERlZmluaWNpb25lcwoKYS4JT2JyYSBDb2xlY3RpdmEgZXMgdW5hIG9icmEsIHRhbCBjb21vIHVuYSBwdWJsaWNhY2nDs24gcGVyacOzZGljYSwgdW5hIGFudG9sb2fDrWEsIG8gdW5hIGVuY2ljbG9wZWRpYSwgZW4gbGEgcXVlIGxhIG9icmEgZW4gc3UgdG90YWxpZGFkLCBzaW4gbW9kaWZpY2FjacOzbiBhbGd1bmEsIGp1bnRvIGNvbiB1biBncnVwbyBkZSBvdHJhcyBjb250cmlidWNpb25lcyBxdWUgY29uc3RpdHV5ZW4gb2JyYXMgc2VwYXJhZGFzIGUgaW5kZXBlbmRpZW50ZXMgZW4gc8OtIG1pc21hcywgc2UgaW50ZWdyYW4gZW4gdW4gdG9kbyBjb2xlY3Rpdm8uIFVuYSBPYnJhIHF1ZSBjb25zdGl0dXllIHVuYSBvYnJhIGNvbGVjdGl2YSBubyBzZSBjb25zaWRlcmFyw6EgdW5hIE9icmEgRGVyaXZhZGEgKGNvbW8gc2UgZGVmaW5lIGFiYWpvKSBwYXJhIGxvcyBwcm9ww7NzaXRvcyBkZSBlc3RhIGxpY2VuY2lhLiBhcXVlbGxhIHByb2R1Y2lkYSBwb3IgdW4gZ3J1cG8gZGUgYXV0b3JlcywgZW4gcXVlIGxhIE9icmEgc2UgZW5jdWVudHJhIHNpbiBtb2RpZmljYWNpb25lcywganVudG8gY29uIHVuYSBjaWVydGEgY2FudGlkYWQgZGUgb3RyYXMgY29udHJpYnVjaW9uZXMsIHF1ZSBjb25zdGl0dXllbiBlbiBzw60gbWlzbW9zIHRyYWJham9zIHNlcGFyYWRvcyBlIGluZGVwZW5kaWVudGVzLCBxdWUgc29uIGludGVncmFkb3MgYWwgdG9kbyBjb2xlY3Rpdm8sIHRhbGVzIGNvbW8gcHVibGljYWNpb25lcyBwZXJpw7NkaWNhcywgYW50b2xvZ8OtYXMgbyBlbmNpY2xvcGVkaWFzLgoKYi4JT2JyYSBEZXJpdmFkYSBzaWduaWZpY2EgdW5hIG9icmEgYmFzYWRhIGVuIGxhIG9icmEgb2JqZXRvIGRlIGVzdGEgbGljZW5jaWEgbyBlbiDDqXN0YSB5IG90cmFzIG9icmFzIHByZWV4aXN0ZW50ZXMsIHRhbGVzIGNvbW8gdHJhZHVjY2lvbmVzLCBhcnJlZ2xvcyBtdXNpY2FsZXMsIGRyYW1hdGl6YWNpb25lcywg4oCcZmljY2lvbmFsaXphY2lvbmVz4oCdLCB2ZXJzaW9uZXMgcGFyYSBjaW5lLCDigJxncmFiYWNpb25lcyBkZSBzb25pZG/igJ0sIHJlcHJvZHVjY2lvbmVzIGRlIGFydGUsIHJlc8O6bWVuZXMsIGNvbmRlbnNhY2lvbmVzLCBvIGN1YWxxdWllciBvdHJhIGVuIGxhIHF1ZSBsYSBvYnJhIHB1ZWRhIHNlciB0cmFuc2Zvcm1hZGEsIGNhbWJpYWRhIG8gYWRhcHRhZGEsIGV4Y2VwdG8gYXF1ZWxsYXMgcXVlIGNvbnN0aXR1eWFuIHVuYSBvYnJhIGNvbGVjdGl2YSwgbGFzIHF1ZSBubyBzZXLDoW4gY29uc2lkZXJhZGFzIHVuYSBvYnJhIGRlcml2YWRhIHBhcmEgZWZlY3RvcyBkZSBlc3RhIGxpY2VuY2lhLiAoUGFyYSBldml0YXIgZHVkYXMsIGVuIGVsIGNhc28gZGUgcXVlIGxhIE9icmEgc2VhIHVuYSBjb21wb3NpY2nDs24gbXVzaWNhbCBvIHVuYSBncmFiYWNpw7NuIHNvbm9yYSwgcGFyYSBsb3MgZWZlY3RvcyBkZSBlc3RhIExpY2VuY2lhIGxhIHNpbmNyb25pemFjacOzbiB0ZW1wb3JhbCBkZSBsYSBPYnJhIGNvbiB1bmEgaW1hZ2VuIGVuIG1vdmltaWVudG8gc2UgY29uc2lkZXJhcsOhIHVuYSBPYnJhIERlcml2YWRhIHBhcmEgbG9zIGZpbmVzIGRlIGVzdGEgbGljZW5jaWEpLgoKYy4JTGljZW5jaWFudGUsIGVzIGVsIGluZGl2aWR1byBvIGxhIGVudGlkYWQgdGl0dWxhciBkZSBsb3MgZGVyZWNob3MgZGUgYXV0b3IgcXVlIG9mcmVjZSBsYSBPYnJhIGVuIGNvbmZvcm1pZGFkIGNvbiBsYXMgY29uZGljaW9uZXMgZGUgZXN0YSBMaWNlbmNpYS4KCmQuCUF1dG9yIG9yaWdpbmFsLCBlcyBlbCBpbmRpdmlkdW8gcXVlIGNyZcOzIGxhIE9icmEuCgplLglPYnJhLCBlcyBhcXVlbGxhIG9icmEgc3VzY2VwdGlibGUgZGUgcHJvdGVjY2nDs24gcG9yIGVsIHLDqWdpbWVuIGRlIERlcmVjaG8gZGUgQXV0b3IgeSBxdWUgZXMgb2ZyZWNpZGEgZW4gbG9zIHTDqXJtaW5vcyBkZSBlc3RhIGxpY2VuY2lhCgpmLglVc3RlZCwgZXMgZWwgaW5kaXZpZHVvIG8gbGEgZW50aWRhZCBxdWUgZWplcmNpdGEgbG9zIGRlcmVjaG9zIG90b3JnYWRvcyBhbCBhbXBhcm8gZGUgZXN0YSBMaWNlbmNpYSB5IHF1ZSBjb24gYW50ZXJpb3JpZGFkIG5vIGhhIHZpb2xhZG8gbGFzIGNvbmRpY2lvbmVzIGRlIGxhIG1pc21hIHJlc3BlY3RvIGEgbGEgT2JyYSwgbyBxdWUgaGF5YSBvYnRlbmlkbyBhdXRvcml6YWNpw7NuIGV4cHJlc2EgcG9yIHBhcnRlIGRlbCBMaWNlbmNpYW50ZSBwYXJhIGVqZXJjZXIgbG9zIGRlcmVjaG9zIGFsIGFtcGFybyBkZSBlc3RhIExpY2VuY2lhIHBlc2UgYSB1bmEgdmlvbGFjacOzbiBhbnRlcmlvci4KCjIuIERlcmVjaG9zIGRlIFVzb3MgSG9ucmFkb3MgeSBleGNlcGNpb25lcyBMZWdhbGVzLgpOYWRhIGVuIGVzdGEgTGljZW5jaWEgcG9kcsOhIHNlciBpbnRlcnByZXRhZG8gY29tbyB1bmEgZGlzbWludWNpw7NuLCBsaW1pdGFjacOzbiBvIHJlc3RyaWNjacOzbiBkZSBsb3MgZGVyZWNob3MgZGVyaXZhZG9zIGRlbCB1c28gaG9ucmFkbyB5IG90cmFzIGxpbWl0YWNpb25lcyBvIGV4Y2VwY2lvbmVzIGEgbG9zIGRlcmVjaG9zIGRlbCBhdXRvciBiYWpvIGVsIHLDqWdpbWVuIGxlZ2FsIHZpZ2VudGUgbyBkZXJpdmFkbyBkZSBjdWFscXVpZXIgb3RyYSBub3JtYSBxdWUgc2UgbGUgYXBsaXF1ZS4KCjMuIENvbmNlc2nDs24gZGUgbGEgTGljZW5jaWEuCkJham8gbG9zIHTDqXJtaW5vcyB5IGNvbmRpY2lvbmVzIGRlIGVzdGEgTGljZW5jaWEsIGVsIExpY2VuY2lhbnRlIG90b3JnYSBhIFVzdGVkIHVuYSBsaWNlbmNpYSBtdW5kaWFsLCBsaWJyZSBkZSByZWdhbMOtYXMsIG5vIGV4Y2x1c2l2YSB5IHBlcnBldHVhIChkdXJhbnRlIHRvZG8gZWwgcGVyw61vZG8gZGUgdmlnZW5jaWEgZGUgbG9zIGRlcmVjaG9zIGRlIGF1dG9yKSBwYXJhIGVqZXJjZXIgZXN0b3MgZGVyZWNob3Mgc29icmUgbGEgT2JyYSB0YWwgeSBjb21vIHNlIGluZGljYSBhIGNvbnRpbnVhY2nDs246CgphLglSZXByb2R1Y2lyIGxhIE9icmEsIGluY29ycG9yYXIgbGEgT2JyYSBlbiB1bmEgbyBtw6FzIE9icmFzIENvbGVjdGl2YXMsIHkgcmVwcm9kdWNpciBsYSBPYnJhIGluY29ycG9yYWRhIGVuIGxhcyBPYnJhcyBDb2xlY3RpdmFzLgoKYi4JRGlzdHJpYnVpciBjb3BpYXMgbyBmb25vZ3JhbWFzIGRlIGxhcyBPYnJhcywgZXhoaWJpcmxhcyBww7pibGljYW1lbnRlLCBlamVjdXRhcmxhcyBww7pibGljYW1lbnRlIHkvbyBwb25lcmxhcyBhIGRpc3Bvc2ljacOzbiBww7pibGljYSwgaW5jbHV5w6luZG9sYXMgY29tbyBpbmNvcnBvcmFkYXMgZW4gT2JyYXMgQ29sZWN0aXZhcywgc2Vnw7puIGNvcnJlc3BvbmRhLgoKYy4JRGlzdHJpYnVpciBjb3BpYXMgZGUgbGFzIE9icmFzIERlcml2YWRhcyBxdWUgc2UgZ2VuZXJlbiwgZXhoaWJpcmxhcyBww7pibGljYW1lbnRlLCBlamVjdXRhcmxhcyBww7pibGljYW1lbnRlIHkvbyBwb25lcmxhcyBhIGRpc3Bvc2ljacOzbiBww7pibGljYS4KTG9zIGRlcmVjaG9zIG1lbmNpb25hZG9zIGFudGVyaW9ybWVudGUgcHVlZGVuIHNlciBlamVyY2lkb3MgZW4gdG9kb3MgbG9zIG1lZGlvcyB5IGZvcm1hdG9zLCBhY3R1YWxtZW50ZSBjb25vY2lkb3MgbyBxdWUgc2UgaW52ZW50ZW4gZW4gZWwgZnV0dXJvLiBMb3MgZGVyZWNob3MgYW50ZXMgbWVuY2lvbmFkb3MgaW5jbHV5ZW4gZWwgZGVyZWNobyBhIHJlYWxpemFyIGRpY2hhcyBtb2RpZmljYWNpb25lcyBlbiBsYSBtZWRpZGEgcXVlIHNlYW4gdMOpY25pY2FtZW50ZSBuZWNlc2FyaWFzIHBhcmEgZWplcmNlciBsb3MgZGVyZWNob3MgZW4gb3RybyBtZWRpbyBvIGZvcm1hdG9zLCBwZXJvIGRlIG90cmEgbWFuZXJhIHVzdGVkIG5vIGVzdMOhIGF1dG9yaXphZG8gcGFyYSByZWFsaXphciBvYnJhcyBkZXJpdmFkYXMuIFRvZG9zIGxvcyBkZXJlY2hvcyBubyBvdG9yZ2Fkb3MgZXhwcmVzYW1lbnRlIHBvciBlbCBMaWNlbmNpYW50ZSBxdWVkYW4gcG9yIGVzdGUgbWVkaW8gcmVzZXJ2YWRvcywgaW5jbHV5ZW5kbyBwZXJvIHNpbiBsaW1pdGFyc2UgYSBhcXVlbGxvcyBxdWUgc2UgbWVuY2lvbmFuIGVuIGxhcyBzZWNjaW9uZXMgNChkKSB5IDQoZSkuCgo0LiBSZXN0cmljY2lvbmVzLgpMYSBsaWNlbmNpYSBvdG9yZ2FkYSBlbiBsYSBhbnRlcmlvciBTZWNjacOzbiAzIGVzdMOhIGV4cHJlc2FtZW50ZSBzdWpldGEgeSBsaW1pdGFkYSBwb3IgbGFzIHNpZ3VpZW50ZXMgcmVzdHJpY2Npb25lczoKCmEuCVVzdGVkIHB1ZWRlIGRpc3RyaWJ1aXIsIGV4aGliaXIgcMO6YmxpY2FtZW50ZSwgZWplY3V0YXIgcMO6YmxpY2FtZW50ZSwgbyBwb25lciBhIGRpc3Bvc2ljacOzbiBww7pibGljYSBsYSBPYnJhIHPDs2xvIGJham8gbGFzIGNvbmRpY2lvbmVzIGRlIGVzdGEgTGljZW5jaWEsIHkgVXN0ZWQgZGViZSBpbmNsdWlyIHVuYSBjb3BpYSBkZSBlc3RhIGxpY2VuY2lhIG8gZGVsIElkZW50aWZpY2Fkb3IgVW5pdmVyc2FsIGRlIFJlY3Vyc29zIGRlIGxhIG1pc21hIGNvbiBjYWRhIGNvcGlhIGRlIGxhIE9icmEgcXVlIGRpc3RyaWJ1eWEsIGV4aGliYSBww7pibGljYW1lbnRlLCBlamVjdXRlIHDDumJsaWNhbWVudGUgbyBwb25nYSBhIGRpc3Bvc2ljacOzbiBww7pibGljYS4gTm8gZXMgcG9zaWJsZSBvZnJlY2VyIG8gaW1wb25lciBuaW5ndW5hIGNvbmRpY2nDs24gc29icmUgbGEgT2JyYSBxdWUgYWx0ZXJlIG8gbGltaXRlIGxhcyBjb25kaWNpb25lcyBkZSBlc3RhIExpY2VuY2lhIG8gZWwgZWplcmNpY2lvIGRlIGxvcyBkZXJlY2hvcyBkZSBsb3MgZGVzdGluYXRhcmlvcyBvdG9yZ2Fkb3MgZW4gZXN0ZSBkb2N1bWVudG8uIE5vIGVzIHBvc2libGUgc3VibGljZW5jaWFyIGxhIE9icmEuIFVzdGVkIGRlYmUgbWFudGVuZXIgaW50YWN0b3MgdG9kb3MgbG9zIGF2aXNvcyBxdWUgaGFnYW4gcmVmZXJlbmNpYSBhIGVzdGEgTGljZW5jaWEgeSBhIGxhIGNsw6F1c3VsYSBkZSBsaW1pdGFjacOzbiBkZSBnYXJhbnTDrWFzLiBVc3RlZCBubyBwdWVkZSBkaXN0cmlidWlyLCBleGhpYmlyIHDDumJsaWNhbWVudGUsIGVqZWN1dGFyIHDDumJsaWNhbWVudGUsIG8gcG9uZXIgYSBkaXNwb3NpY2nDs24gcMO6YmxpY2EgbGEgT2JyYSBjb24gYWxndW5hIG1lZGlkYSB0ZWNub2zDs2dpY2EgcXVlIGNvbnRyb2xlIGVsIGFjY2VzbyBvIGxhIHV0aWxpemFjacOzbiBkZSBlbGxhIGRlIHVuYSBmb3JtYSBxdWUgc2VhIGluY29uc2lzdGVudGUgY29uIGxhcyBjb25kaWNpb25lcyBkZSBlc3RhIExpY2VuY2lhLiBMbyBhbnRlcmlvciBzZSBhcGxpY2EgYSBsYSBPYnJhIGluY29ycG9yYWRhIGEgdW5hIE9icmEgQ29sZWN0aXZhLCBwZXJvIGVzdG8gbm8gZXhpZ2UgcXVlIGxhIE9icmEgQ29sZWN0aXZhIGFwYXJ0ZSBkZSBsYSBvYnJhIG1pc21hIHF1ZWRlIHN1amV0YSBhIGxhcyBjb25kaWNpb25lcyBkZSBlc3RhIExpY2VuY2lhLiBTaSBVc3RlZCBjcmVhIHVuYSBPYnJhIENvbGVjdGl2YSwgcHJldmlvIGF2aXNvIGRlIGN1YWxxdWllciBMaWNlbmNpYW50ZSBkZWJlLCBlbiBsYSBtZWRpZGEgZGUgbG8gcG9zaWJsZSwgZWxpbWluYXIgZGUgbGEgT2JyYSBDb2xlY3RpdmEgY3VhbHF1aWVyIHJlZmVyZW5jaWEgYSBkaWNobyBMaWNlbmNpYW50ZSBvIGFsIEF1dG9yIE9yaWdpbmFsLCBzZWfDum4gbG8gc29saWNpdGFkbyBwb3IgZWwgTGljZW5jaWFudGUgeSBjb25mb3JtZSBsbyBleGlnZSBsYSBjbMOhdXN1bGEgNChjKS4KCmIuCVVzdGVkIG5vIHB1ZWRlIGVqZXJjZXIgbmluZ3VubyBkZSBsb3MgZGVyZWNob3MgcXVlIGxlIGhhbiBzaWRvIG90b3JnYWRvcyBlbiBsYSBTZWNjacOzbiAzIHByZWNlZGVudGUgZGUgbW9kbyBxdWUgZXN0w6luIHByaW5jaXBhbG1lbnRlIGRlc3RpbmFkb3MgbyBkaXJlY3RhbWVudGUgZGlyaWdpZG9zIGEgY29uc2VndWlyIHVuIHByb3ZlY2hvIGNvbWVyY2lhbCBvIHVuYSBjb21wZW5zYWNpw7NuIG1vbmV0YXJpYSBwcml2YWRhLiBFbCBpbnRlcmNhbWJpbyBkZSBsYSBPYnJhIHBvciBvdHJhcyBvYnJhcyBwcm90ZWdpZGFzIHBvciBkZXJlY2hvcyBkZSBhdXRvciwgeWEgc2VhIGEgdHJhdsOpcyBkZSB1biBzaXN0ZW1hIHBhcmEgY29tcGFydGlyIGFyY2hpdm9zIGRpZ2l0YWxlcyAoZGlnaXRhbCBmaWxlLXNoYXJpbmcpIG8gZGUgY3VhbHF1aWVyIG90cmEgbWFuZXJhIG5vIHNlcsOhIGNvbnNpZGVyYWRvIGNvbW8gZXN0YXIgZGVzdGluYWRvIHByaW5jaXBhbG1lbnRlIG8gZGlyaWdpZG8gZGlyZWN0YW1lbnRlIGEgY29uc2VndWlyIHVuIHByb3ZlY2hvIGNvbWVyY2lhbCBvIHVuYSBjb21wZW5zYWNpw7NuIG1vbmV0YXJpYSBwcml2YWRhLCBzaWVtcHJlIHF1ZSBubyBzZSByZWFsaWNlIHVuIHBhZ28gbWVkaWFudGUgdW5hIGNvbXBlbnNhY2nDs24gbW9uZXRhcmlhIGVuIHJlbGFjacOzbiBjb24gZWwgaW50ZXJjYW1iaW8gZGUgb2JyYXMgcHJvdGVnaWRhcyBwb3IgZWwgZGVyZWNobyBkZSBhdXRvci4KCmMuCVNpIHVzdGVkIGRpc3RyaWJ1eWUsIGV4aGliZSBww7pibGljYW1lbnRlLCBlamVjdXRhIHDDumJsaWNhbWVudGUgbyBlamVjdXRhIHDDumJsaWNhbWVudGUgZW4gZm9ybWEgZGlnaXRhbCBsYSBPYnJhIG8gY3VhbHF1aWVyIE9icmEgRGVyaXZhZGEgdSBPYnJhIENvbGVjdGl2YSwgVXN0ZWQgZGViZSBtYW50ZW5lciBpbnRhY3RhIHRvZGEgbGEgaW5mb3JtYWNpw7NuIGRlIGRlcmVjaG8gZGUgYXV0b3IgZGUgbGEgT2JyYSB5IHByb3BvcmNpb25hciwgZGUgZm9ybWEgcmF6b25hYmxlIHNlZ8O6biBlbCBtZWRpbyBvIG1hbmVyYSBxdWUgVXN0ZWQgZXN0w6kgdXRpbGl6YW5kbzogKGkpIGVsIG5vbWJyZSBkZWwgQXV0b3IgT3JpZ2luYWwgc2kgZXN0w6EgcHJvdmlzdG8gKG8gc2V1ZMOzbmltbywgc2kgZnVlcmUgYXBsaWNhYmxlKSwgeS9vIChpaSkgZWwgbm9tYnJlIGRlIGxhIHBhcnRlIG8gbGFzIHBhcnRlcyBxdWUgZWwgQXV0b3IgT3JpZ2luYWwgeS9vIGVsIExpY2VuY2lhbnRlIGh1YmllcmVuIGRlc2lnbmFkbyBwYXJhIGxhIGF0cmlidWNpw7NuICh2LmcuLCB1biBpbnN0aXR1dG8gcGF0cm9jaW5hZG9yLCBlZGl0b3JpYWwsIHB1YmxpY2FjacOzbikgZW4gbGEgaW5mb3JtYWNpw7NuIGRlIGxvcyBkZXJlY2hvcyBkZSBhdXRvciBkZWwgTGljZW5jaWFudGUsIHTDqXJtaW5vcyBkZSBzZXJ2aWNpb3MgbyBkZSBvdHJhcyBmb3JtYXMgcmF6b25hYmxlczsgZWwgdMOtdHVsbyBkZSBsYSBPYnJhIHNpIGVzdMOhIHByb3Zpc3RvOyBlbiBsYSBtZWRpZGEgZGUgbG8gcmF6b25hYmxlbWVudGUgZmFjdGlibGUgeSwgc2kgZXN0w6EgcHJvdmlzdG8sIGVsIElkZW50aWZpY2Fkb3IgVW5pZm9ybWUgZGUgUmVjdXJzb3MgKFVuaWZvcm0gUmVzb3VyY2UgSWRlbnRpZmllcikgcXVlIGVsIExpY2VuY2lhbnRlIGVzcGVjaWZpY2EgcGFyYSBzZXIgYXNvY2lhZG8gY29uIGxhIE9icmEsIHNhbHZvIHF1ZSB0YWwgVVJJIG5vIHNlIHJlZmllcmEgYSBsYSBub3RhIHNvYnJlIGxvcyBkZXJlY2hvcyBkZSBhdXRvciBvIGEgbGEgaW5mb3JtYWNpw7NuIHNvYnJlIGVsIGxpY2VuY2lhbWllbnRvIGRlIGxhIE9icmE7IHkgZW4gZWwgY2FzbyBkZSB1bmEgT2JyYSBEZXJpdmFkYSwgYXRyaWJ1aXIgZWwgY3LDqWRpdG8gaWRlbnRpZmljYW5kbyBlbCB1c28gZGUgbGEgT2JyYSBlbiBsYSBPYnJhIERlcml2YWRhICh2LmcuLCAiVHJhZHVjY2nDs24gRnJhbmNlc2EgZGUgbGEgT2JyYSBkZWwgQXV0b3IgT3JpZ2luYWwsIiBvICJHdWnDs24gQ2luZW1hdG9ncsOhZmljbyBiYXNhZG8gZW4gbGEgT2JyYSBvcmlnaW5hbCBkZWwgQXV0b3IgT3JpZ2luYWwiKS4gVGFsIGNyw6lkaXRvIHB1ZWRlIHNlciBpbXBsZW1lbnRhZG8gZGUgY3VhbHF1aWVyIGZvcm1hIHJhem9uYWJsZTsgZW4gZWwgY2Fzbywgc2luIGVtYmFyZ28sIGRlIE9icmFzIERlcml2YWRhcyB1IE9icmFzIENvbGVjdGl2YXMsIHRhbCBjcsOpZGl0byBhcGFyZWNlcsOhLCBjb21vIG3DrW5pbW8sIGRvbmRlIGFwYXJlY2UgZWwgY3LDqWRpdG8gZGUgY3VhbHF1aWVyIG90cm8gYXV0b3IgY29tcGFyYWJsZSB5IGRlIHVuYSBtYW5lcmEsIGFsIG1lbm9zLCB0YW4gZGVzdGFjYWRhIGNvbW8gZWwgY3LDqWRpdG8gZGUgb3RybyBhdXRvciBjb21wYXJhYmxlLgoKZC4JUGFyYSBldml0YXIgdG9kYSBjb25mdXNpw7NuLCBlbCBMaWNlbmNpYW50ZSBhY2xhcmEgcXVlLCBjdWFuZG8gbGEgb2JyYSBlcyB1bmEgY29tcG9zaWNpw7NuIG11c2ljYWw6CgppLglSZWdhbMOtYXMgcG9yIGludGVycHJldGFjacOzbiB5IGVqZWN1Y2nDs24gYmFqbyBsaWNlbmNpYXMgZ2VuZXJhbGVzLiBFbCBMaWNlbmNpYW50ZSBzZSByZXNlcnZhIGVsIGRlcmVjaG8gZXhjbHVzaXZvIGRlIGF1dG9yaXphciBsYSBlamVjdWNpw7NuIHDDumJsaWNhIG8gbGEgZWplY3VjacOzbiBww7pibGljYSBkaWdpdGFsIGRlIGxhIG9icmEgeSBkZSByZWNvbGVjdGFyLCBzZWEgaW5kaXZpZHVhbG1lbnRlIG8gYSB0cmF2w6lzIGRlIHVuYSBzb2NpZWRhZCBkZSBnZXN0acOzbiBjb2xlY3RpdmEgZGUgZGVyZWNob3MgZGUgYXV0b3IgeSBkZXJlY2hvcyBjb25leG9zIChwb3IgZWplbXBsbywgU0FZQ08pLCBsYXMgcmVnYWzDrWFzIHBvciBsYSBlamVjdWNpw7NuIHDDumJsaWNhIG8gcG9yIGxhIGVqZWN1Y2nDs24gcMO6YmxpY2EgZGlnaXRhbCBkZSBsYSBvYnJhIChwb3IgZWplbXBsbyBXZWJjYXN0KSBsaWNlbmNpYWRhIGJham8gbGljZW5jaWFzIGdlbmVyYWxlcywgc2kgbGEgaW50ZXJwcmV0YWNpw7NuIG8gZWplY3VjacOzbiBkZSBsYSBvYnJhIGVzdMOhIHByaW1vcmRpYWxtZW50ZSBvcmllbnRhZGEgcG9yIG8gZGlyaWdpZGEgYSBsYSBvYnRlbmNpw7NuIGRlIHVuYSB2ZW50YWphIGNvbWVyY2lhbCBvIHVuYSBjb21wZW5zYWNpw7NuIG1vbmV0YXJpYSBwcml2YWRhLgoKaWkuCVJlZ2Fsw61hcyBwb3IgRm9ub2dyYW1hcy4gRWwgTGljZW5jaWFudGUgc2UgcmVzZXJ2YSBlbCBkZXJlY2hvIGV4Y2x1c2l2byBkZSByZWNvbGVjdGFyLCBpbmRpdmlkdWFsbWVudGUgbyBhIHRyYXbDqXMgZGUgdW5hIHNvY2llZGFkIGRlIGdlc3Rpw7NuIGNvbGVjdGl2YSBkZSBkZXJlY2hvcyBkZSBhdXRvciB5IGRlcmVjaG9zIGNvbmV4b3MgKHBvciBlamVtcGxvLCBsb3MgY29uc2FncmFkb3MgcG9yIGxhIFNBWUNPKSwgdW5hIGFnZW5jaWEgZGUgZGVyZWNob3MgbXVzaWNhbGVzIG8gYWxnw7puIGFnZW50ZSBkZXNpZ25hZG8sIGxhcyByZWdhbMOtYXMgcG9yIGN1YWxxdWllciBmb25vZ3JhbWEgcXVlIFVzdGVkIGNyZWUgYSBwYXJ0aXIgZGUgbGEgb2JyYSAo4oCcdmVyc2nDs24gY292ZXLigJ0pIHkgZGlzdHJpYnV5YSwgZW4gbG9zIHTDqXJtaW5vcyBkZWwgcsOpZ2ltZW4gZGUgZGVyZWNob3MgZGUgYXV0b3IsIHNpIGxhIGNyZWFjacOzbiBvIGRpc3RyaWJ1Y2nDs24gZGUgZXNhIHZlcnNpw7NuIGNvdmVyIGVzdMOhIHByaW1vcmRpYWxtZW50ZSBkZXN0aW5hZGEgbyBkaXJpZ2lkYSBhIG9idGVuZXIgdW5hIHZlbnRhamEgY29tZXJjaWFsIG8gdW5hIGNvbXBlbnNhY2nDs24gbW9uZXRhcmlhIHByaXZhZGEuCgplLglHZXN0acOzbiBkZSBEZXJlY2hvcyBkZSBBdXRvciBzb2JyZSBJbnRlcnByZXRhY2lvbmVzIHkgRWplY3VjaW9uZXMgRGlnaXRhbGVzIChXZWJDYXN0aW5nKS4gUGFyYSBldml0YXIgdG9kYSBjb25mdXNpw7NuLCBlbCBMaWNlbmNpYW50ZSBhY2xhcmEgcXVlLCBjdWFuZG8gbGEgb2JyYSBzZWEgdW4gZm9ub2dyYW1hLCBlbCBMaWNlbmNpYW50ZSBzZSByZXNlcnZhIGVsIGRlcmVjaG8gZXhjbHVzaXZvIGRlIGF1dG9yaXphciBsYSBlamVjdWNpw7NuIHDDumJsaWNhIGRpZ2l0YWwgZGUgbGEgb2JyYSAocG9yIGVqZW1wbG8sIHdlYmNhc3QpIHkgZGUgcmVjb2xlY3RhciwgaW5kaXZpZHVhbG1lbnRlIG8gYSB0cmF2w6lzIGRlIHVuYSBzb2NpZWRhZCBkZSBnZXN0acOzbiBjb2xlY3RpdmEgZGUgZGVyZWNob3MgZGUgYXV0b3IgeSBkZXJlY2hvcyBjb25leG9zIChwb3IgZWplbXBsbywgQUNJTlBSTyksIGxhcyByZWdhbMOtYXMgcG9yIGxhIGVqZWN1Y2nDs24gcMO6YmxpY2EgZGlnaXRhbCBkZSBsYSBvYnJhIChwb3IgZWplbXBsbywgd2ViY2FzdCksIHN1amV0YSBhIGxhcyBkaXNwb3NpY2lvbmVzIGFwbGljYWJsZXMgZGVsIHLDqWdpbWVuIGRlIERlcmVjaG8gZGUgQXV0b3IsIHNpIGVzdGEgZWplY3VjacOzbiBww7pibGljYSBkaWdpdGFsIGVzdMOhIHByaW1vcmRpYWxtZW50ZSBkaXJpZ2lkYSBhIG9idGVuZXIgdW5hIHZlbnRhamEgY29tZXJjaWFsIG8gdW5hIGNvbXBlbnNhY2nDs24gbW9uZXRhcmlhIHByaXZhZGEuCgo1LiBSZXByZXNlbnRhY2lvbmVzLCBHYXJhbnTDrWFzIHkgTGltaXRhY2lvbmVzIGRlIFJlc3BvbnNhYmlsaWRhZC4KQSBNRU5PUyBRVUUgTEFTIFBBUlRFUyBMTyBBQ09SREFSQU4gREUgT1RSQSBGT1JNQSBQT1IgRVNDUklUTywgRUwgTElDRU5DSUFOVEUgT0ZSRUNFIExBIE9CUkEgKEVOIEVMIEVTVEFETyBFTiBFTCBRVUUgU0UgRU5DVUVOVFJBKSDigJxUQUwgQ1VBTOKAnSwgU0lOIEJSSU5EQVIgR0FSQU5Uw41BUyBERSBDTEFTRSBBTEdVTkEgUkVTUEVDVE8gREUgTEEgT0JSQSwgWUEgU0VBIEVYUFJFU0EsIElNUEzDjUNJVEEsIExFR0FMIE8gQ1VBTFFVSUVSQSBPVFJBLCBJTkNMVVlFTkRPLCBTSU4gTElNSVRBUlNFIEEgRUxMQVMsIEdBUkFOVMONQVMgREUgVElUVUxBUklEQUQsIENPTUVSQ0lBQklMSURBRCwgQURBUFRBQklMSURBRCBPIEFERUNVQUNJw5NOIEEgUFJPUMOTU0lUTyBERVRFUk1JTkFETywgQVVTRU5DSUEgREUgSU5GUkFDQ0nDk04sIERFIEFVU0VOQ0lBIERFIERFRkVDVE9TIExBVEVOVEVTIE8gREUgT1RSTyBUSVBPLCBPIExBIFBSRVNFTkNJQSBPIEFVU0VOQ0lBIERFIEVSUk9SRVMsIFNFQU4gTyBOTyBERVNDVUJSSUJMRVMgKFBVRURBTiBPIE5PIFNFUiBFU1RPUyBERVNDVUJJRVJUT1MpLiBBTEdVTkFTIEpVUklTRElDQ0lPTkVTIE5PIFBFUk1JVEVOIExBIEVYQ0xVU0nDk04gREUgR0FSQU5Uw41BUyBJTVBMw41DSVRBUywgRU4gQ1VZTyBDQVNPIEVTVEEgRVhDTFVTScOTTiBQVUVERSBOTyBBUExJQ0FSU0UgQSBVU1RFRC4KCjYuIExpbWl0YWNpw7NuIGRlIHJlc3BvbnNhYmlsaWRhZC4KQSBNRU5PUyBRVUUgTE8gRVhJSkEgRVhQUkVTQU1FTlRFIExBIExFWSBBUExJQ0FCTEUsIEVMIExJQ0VOQ0lBTlRFIE5PIFNFUsOBIFJFU1BPTlNBQkxFIEFOVEUgVVNURUQgUE9SIERBw5FPIEFMR1VOTywgU0VBIFBPUiBSRVNQT05TQUJJTElEQUQgRVhUUkFDT05UUkFDVFVBTCwgUFJFQ09OVFJBQ1RVQUwgTyBDT05UUkFDVFVBTCwgT0JKRVRJVkEgTyBTVUJKRVRJVkEsIFNFIFRSQVRFIERFIERBw5FPUyBNT1JBTEVTIE8gUEFUUklNT05JQUxFUywgRElSRUNUT1MgTyBJTkRJUkVDVE9TLCBQUkVWSVNUT1MgTyBJTVBSRVZJU1RPUyBQUk9EVUNJRE9TIFBPUiBFTCBVU08gREUgRVNUQSBMSUNFTkNJQSBPIERFIExBIE9CUkEsIEFVTiBDVUFORE8gRUwgTElDRU5DSUFOVEUgSEFZQSBTSURPIEFEVkVSVElETyBERSBMQSBQT1NJQklMSURBRCBERSBESUNIT1MgREHDkU9TLiBBTEdVTkFTIExFWUVTIE5PIFBFUk1JVEVOIExBIEVYQ0xVU0nDk04gREUgQ0lFUlRBIFJFU1BPTlNBQklMSURBRCwgRU4gQ1VZTyBDQVNPIEVTVEEgRVhDTFVTScOTTiBQVUVERSBOTyBBUExJQ0FSU0UgQSBVU1RFRC4KCjcuIFTDqXJtaW5vLgoKYS4JRXN0YSBMaWNlbmNpYSB5IGxvcyBkZXJlY2hvcyBvdG9yZ2Fkb3MgZW4gdmlydHVkIGRlIGVsbGEgdGVybWluYXLDoW4gYXV0b23DoXRpY2FtZW50ZSBzaSBVc3RlZCBpbmZyaW5nZSBhbGd1bmEgY29uZGljacOzbiBlc3RhYmxlY2lkYSBlbiBlbGxhLiBTaW4gZW1iYXJnbywgbG9zIGluZGl2aWR1b3MgbyBlbnRpZGFkZXMgcXVlIGhhbiByZWNpYmlkbyBPYnJhcyBEZXJpdmFkYXMgbyBDb2xlY3RpdmFzIGRlIFVzdGVkIGRlIGNvbmZvcm1pZGFkIGNvbiBlc3RhIExpY2VuY2lhLCBubyB2ZXLDoW4gdGVybWluYWRhcyBzdXMgbGljZW5jaWFzLCBzaWVtcHJlIHF1ZSBlc3RvcyBpbmRpdmlkdW9zIG8gZW50aWRhZGVzIHNpZ2FuIGN1bXBsaWVuZG8gw61udGVncmFtZW50ZSBsYXMgY29uZGljaW9uZXMgZGUgZXN0YXMgbGljZW5jaWFzLiBMYXMgU2VjY2lvbmVzIDEsIDIsIDUsIDYsIDcsIHkgOCBzdWJzaXN0aXLDoW4gYSBjdWFscXVpZXIgdGVybWluYWNpw7NuIGRlIGVzdGEgTGljZW5jaWEuCgpiLglTdWpldGEgYSBsYXMgY29uZGljaW9uZXMgeSB0w6lybWlub3MgYW50ZXJpb3JlcywgbGEgbGljZW5jaWEgb3RvcmdhZGEgYXF1w60gZXMgcGVycGV0dWEgKGR1cmFudGUgZWwgcGVyw61vZG8gZGUgdmlnZW5jaWEgZGUgbG9zIGRlcmVjaG9zIGRlIGF1dG9yIGRlIGxhIG9icmEpLiBObyBvYnN0YW50ZSBsbyBhbnRlcmlvciwgZWwgTGljZW5jaWFudGUgc2UgcmVzZXJ2YSBlbCBkZXJlY2hvIGEgcHVibGljYXIgeS9vIGVzdHJlbmFyIGxhIE9icmEgYmFqbyBjb25kaWNpb25lcyBkZSBsaWNlbmNpYSBkaWZlcmVudGVzIG8gYSBkZWphciBkZSBkaXN0cmlidWlybGEgZW4gbG9zIHTDqXJtaW5vcyBkZSBlc3RhIExpY2VuY2lhIGVuIGN1YWxxdWllciBtb21lbnRvOyBlbiBlbCBlbnRlbmRpZG8sIHNpbiBlbWJhcmdvLCBxdWUgZXNhIGVsZWNjacOzbiBubyBzZXJ2aXLDoSBwYXJhIHJldm9jYXIgZXN0YSBsaWNlbmNpYSBvIHF1ZSBkZWJhIHNlciBvdG9yZ2FkYSAsIGJham8gbG9zIHTDqXJtaW5vcyBkZSBlc3RhIGxpY2VuY2lhKSwgeSBlc3RhIGxpY2VuY2lhIGNvbnRpbnVhcsOhIGVuIHBsZW5vIHZpZ29yIHkgZWZlY3RvIGEgbWVub3MgcXVlIHNlYSB0ZXJtaW5hZGEgY29tbyBzZSBleHByZXNhIGF0csOhcy4gTGEgTGljZW5jaWEgcmV2b2NhZGEgY29udGludWFyw6Egc2llbmRvIHBsZW5hbWVudGUgdmlnZW50ZSB5IGVmZWN0aXZhIHNpIG5vIHNlIGxlIGRhIHTDqXJtaW5vIGVuIGxhcyBjb25kaWNpb25lcyBpbmRpY2FkYXMgYW50ZXJpb3JtZW50ZS4KCjguIFZhcmlvcy4KCmEuCUNhZGEgdmV6IHF1ZSBVc3RlZCBkaXN0cmlidXlhIG8gcG9uZ2EgYSBkaXNwb3NpY2nDs24gcMO6YmxpY2EgbGEgT2JyYSBvIHVuYSBPYnJhIENvbGVjdGl2YSwgZWwgTGljZW5jaWFudGUgb2ZyZWNlcsOhIGFsIGRlc3RpbmF0YXJpbyB1bmEgbGljZW5jaWEgZW4gbG9zIG1pc21vcyB0w6lybWlub3MgeSBjb25kaWNpb25lcyBxdWUgbGEgbGljZW5jaWEgb3RvcmdhZGEgYSBVc3RlZCBiYWpvIGVzdGEgTGljZW5jaWEuCgpiLglTaSBhbGd1bmEgZGlzcG9zaWNpw7NuIGRlIGVzdGEgTGljZW5jaWEgcmVzdWx0YSBpbnZhbGlkYWRhIG8gbm8gZXhpZ2libGUsIHNlZ8O6biBsYSBsZWdpc2xhY2nDs24gdmlnZW50ZSwgZXN0byBubyBhZmVjdGFyw6EgbmkgbGEgdmFsaWRleiBuaSBsYSBhcGxpY2FiaWxpZGFkIGRlbCByZXN0byBkZSBjb25kaWNpb25lcyBkZSBlc3RhIExpY2VuY2lhIHksIHNpbiBhY2Npw7NuIGFkaWNpb25hbCBwb3IgcGFydGUgZGUgbG9zIHN1amV0b3MgZGUgZXN0ZSBhY3VlcmRvLCBhcXXDqWxsYSBzZSBlbnRlbmRlcsOhIHJlZm9ybWFkYSBsbyBtw61uaW1vIG5lY2VzYXJpbyBwYXJhIGhhY2VyIHF1ZSBkaWNoYSBkaXNwb3NpY2nDs24gc2VhIHbDoWxpZGEgeSBleGlnaWJsZS4KCmMuCU5pbmfDum4gdMOpcm1pbm8gbyBkaXNwb3NpY2nDs24gZGUgZXN0YSBMaWNlbmNpYSBzZSBlc3RpbWFyw6EgcmVudW5jaWFkYSB5IG5pbmd1bmEgdmlvbGFjacOzbiBkZSBlbGxhIHNlcsOhIGNvbnNlbnRpZGEgYSBtZW5vcyBxdWUgZXNhIHJlbnVuY2lhIG8gY29uc2VudGltaWVudG8gc2VhIG90b3JnYWRvIHBvciBlc2NyaXRvIHkgZmlybWFkbyBwb3IgbGEgcGFydGUgcXVlIHJlbnVuY2llIG8gY29uc2llbnRhLgoKZC4JRXN0YSBMaWNlbmNpYSByZWZsZWphIGVsIGFjdWVyZG8gcGxlbm8gZW50cmUgbGFzIHBhcnRlcyByZXNwZWN0byBhIGxhIE9icmEgYXF1w60gbGljZW5jaWFkYS4gTm8gaGF5IGFycmVnbG9zLCBhY3VlcmRvcyBvIGRlY2xhcmFjaW9uZXMgcmVzcGVjdG8gYSBsYSBPYnJhIHF1ZSBubyBlc3TDqW4gZXNwZWNpZmljYWRvcyBlbiBlc3RlIGRvY3VtZW50by4gRWwgTGljZW5jaWFudGUgbm8gc2UgdmVyw6EgbGltaXRhZG8gcG9yIG5pbmd1bmEgZGlzcG9zaWNpw7NuIGFkaWNpb25hbCBxdWUgcHVlZGEgc3VyZ2lyIGVuIGFsZ3VuYSBjb211bmljYWNpw7NuIGVtYW5hZGEgZGUgVXN0ZWQuIEVzdGEgTGljZW5jaWEgbm8gcHVlZGUgc2VyIG1vZGlmaWNhZGEgc2luIGVsIGNvbnNlbnRpbWllbnRvIG11dHVvIHBvciBlc2NyaXRvIGRlbCBMaWNlbmNpYW50ZSB5IFVzdGVkLgo= |