Toward an automatic 3D measurement of skin wheals from skin prick tests

The skin prick test (SPT) is the standard method for the diagnosis of allergies. It consists in placing an array of allergen drops on the skin of a patient, typically the volar forearm, and pricking them with a lancet to provoke a specific dermal reaction described as a wheal. The diagnosis is perfo...

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Autores:
Tipo de recurso:
Fecha de publicación:
2019
Institución:
Universidad Tecnológica de Bolívar
Repositorio:
Repositorio Institucional UTB
Idioma:
eng
OAI Identifier:
oai:repositorio.utb.edu.co:20.500.12585/9187
Acceso en línea:
https://hdl.handle.net/20.500.12585/9187
Palabra clave:
3D medical imaging
3D skin measurement
Allergy diagnosis
Fourier transform profilometry
Fringe projection
Skin prick test
Skin wheals
Allergies
Data handling
Diagnosis
Imaging systems
Medical imaging
Profilometry
3D data processing
Automatic measurements
Conventional approach
Diagnosis of allergies
Fourier transform profilometry
Fringe projection
Observer variations
Skin prick test
Image reconstruction
Rights
restrictedAccess
License
http://creativecommons.org/licenses/by-nc-nd/4.0/
Description
Summary:The skin prick test (SPT) is the standard method for the diagnosis of allergies. It consists in placing an array of allergen drops on the skin of a patient, typically the volar forearm, and pricking them with a lancet to provoke a specific dermal reaction described as a wheal. The diagnosis is performed by measuring the diameter of the skin wheals, although wheals are not usually circular which leads to measurement inconsistencies. Moreover, the conventional approach is to measure their size with a ruler. This method has been proven prone to inter- and intra-observer variations. We have developed a 3D imaging system for the 3D reconstruction of the SPT. Here, we describe the proposed method for the automatic measurements of the wheals based on 3D data processing to yield reliable results. The method is based on a robust parametric fitting to the 3D data for obtaining the diameter directly. We evaluate the repeatability of the system under 3D reconstructions for different object poses. Although the system provides higher accuracy in the measurement, we compare the results to those produced by a physician. Copyright © 2019 SPIE.