Umbilical cord and preeclampsia
Preeclampsia is associated with abnormalities in the umbilical cord in several ways: morphological, biochemical and functional. Alteration in blood vessels of the placenta, decidua and circulatory system of the fetus might be related to factors that cause preeclampsia and may be associated with alte...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2016
- Institución:
- Universidad Tecnológica de Bolívar
- Repositorio:
- Repositorio Institucional UTB
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.utb.edu.co:20.500.12585/8990
- Acceso en línea:
- https://hdl.handle.net/20.500.12585/8990
- Palabra clave:
- Eclampsia
Gestational hypertension
HELLP syndrome
Placenta
Pregnancy
Adult
Article
Chronic disease
Chronic hypertension
Disease association
Eclampsia
Embryo
Female
Fetus
Human
Hypercoiling umbilical cord
Hypocoiling umbilical cord
Major clinical study
Male
Marginal umbilical cord insertion
Maternal hypertension
Paramarginal umbilical cord insertion
Preeclampsia
Prematurity
Priority journal
Single umbilical artery
Superimposed preeclampsia
Umbilical cord
Umbilical malformation
Abnormalities
Autopsy
Colombia
Fetal Growth Retardation
Fetomaternal transfusion
Lesions and defects
Newborn
Pathology
Placenta
Preeclampsia
Pregnancy
Prospective study
Vascularization
Adult
Autopsy
Colombia
Dilatation, Pathologic
Female
Fetal Growth Retardation
Humans
Infant, Newborn
Male
Maternal-Fetal Exchange
Placenta
Pre-Eclampsia
Pregnancy
Prospective Studies
Umbilical Cord
- Rights
- restrictedAccess
- License
- http://creativecommons.org/licenses/by-nc-nd/4.0/
id |
UTB2_59e42b955344628adf062cb1931a3626 |
---|---|
oai_identifier_str |
oai:repositorio.utb.edu.co:20.500.12585/8990 |
network_acronym_str |
UTB2 |
network_name_str |
Repositorio Institucional UTB |
repository_id_str |
|
dc.title.none.fl_str_mv |
Umbilical cord and preeclampsia |
title |
Umbilical cord and preeclampsia |
spellingShingle |
Umbilical cord and preeclampsia Eclampsia Gestational hypertension HELLP syndrome Placenta Pregnancy Adult Article Chronic disease Chronic hypertension Disease association Eclampsia Embryo Female Fetus Human Hypercoiling umbilical cord Hypocoiling umbilical cord Major clinical study Male Marginal umbilical cord insertion Maternal hypertension Paramarginal umbilical cord insertion Preeclampsia Prematurity Priority journal Single umbilical artery Superimposed preeclampsia Umbilical cord Umbilical malformation Abnormalities Autopsy Colombia Fetal Growth Retardation Fetomaternal transfusion Lesions and defects Newborn Pathology Placenta Preeclampsia Pregnancy Prospective study Vascularization Adult Autopsy Colombia Dilatation, Pathologic Female Fetal Growth Retardation Humans Infant, Newborn Male Maternal-Fetal Exchange Placenta Pre-Eclampsia Pregnancy Prospective Studies Umbilical Cord |
title_short |
Umbilical cord and preeclampsia |
title_full |
Umbilical cord and preeclampsia |
title_fullStr |
Umbilical cord and preeclampsia |
title_full_unstemmed |
Umbilical cord and preeclampsia |
title_sort |
Umbilical cord and preeclampsia |
dc.subject.keywords.none.fl_str_mv |
Eclampsia Gestational hypertension HELLP syndrome Placenta Pregnancy Adult Article Chronic disease Chronic hypertension Disease association Eclampsia Embryo Female Fetus Human Hypercoiling umbilical cord Hypocoiling umbilical cord Major clinical study Male Marginal umbilical cord insertion Maternal hypertension Paramarginal umbilical cord insertion Preeclampsia Prematurity Priority journal Single umbilical artery Superimposed preeclampsia Umbilical cord Umbilical malformation Abnormalities Autopsy Colombia Fetal Growth Retardation Fetomaternal transfusion Lesions and defects Newborn Pathology Placenta Preeclampsia Pregnancy Prospective study Vascularization Adult Autopsy Colombia Dilatation, Pathologic Female Fetal Growth Retardation Humans Infant, Newborn Male Maternal-Fetal Exchange Placenta Pre-Eclampsia Pregnancy Prospective Studies Umbilical Cord |
topic |
Eclampsia Gestational hypertension HELLP syndrome Placenta Pregnancy Adult Article Chronic disease Chronic hypertension Disease association Eclampsia Embryo Female Fetus Human Hypercoiling umbilical cord Hypocoiling umbilical cord Major clinical study Male Marginal umbilical cord insertion Maternal hypertension Paramarginal umbilical cord insertion Preeclampsia Prematurity Priority journal Single umbilical artery Superimposed preeclampsia Umbilical cord Umbilical malformation Abnormalities Autopsy Colombia Fetal Growth Retardation Fetomaternal transfusion Lesions and defects Newborn Pathology Placenta Preeclampsia Pregnancy Prospective study Vascularization Adult Autopsy Colombia Dilatation, Pathologic Female Fetal Growth Retardation Humans Infant, Newborn Male Maternal-Fetal Exchange Placenta Pre-Eclampsia Pregnancy Prospective Studies Umbilical Cord |
description |
Preeclampsia is associated with abnormalities in the umbilical cord in several ways: morphological, biochemical and functional. Alteration in blood vessels of the placenta, decidua and circulatory system of the fetus might be related to factors that cause preeclampsia and may be associated with alterations of the umbilical cord. OBJECTIVES: This study aimed to analyze the relationship between each type of umbilical cord abnormality and the different subtypes of hypertensive gestational disorders. METHODS: We conducted a prospective study on consecutive autopsies and its placentas, looking for abnormalities in the umbilical cord's features and their clinical associations. RESULTS: Umbilical cord abnormalities including length, diameter, insertion, entanglements, knots and coils were associated with maternal gestational hypertension. CONCLUSION:Inwomen with gestational hypertension, umbilical cord abnormalities are associated with fetal and neonatal consequences. © 2016 IOS Press and the authors. |
publishDate |
2016 |
dc.date.issued.none.fl_str_mv |
2016 |
dc.date.accessioned.none.fl_str_mv |
2020-03-26T16:32:43Z |
dc.date.available.none.fl_str_mv |
2020-03-26T16:32:43Z |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.driver.none.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.hasVersion.none.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.spa.none.fl_str_mv |
Artículo |
status_str |
publishedVersion |
dc.identifier.citation.none.fl_str_mv |
Journal of Neonatal-Perinatal Medicine; Vol. 9, Núm. 1; pp. 49-57 |
dc.identifier.issn.none.fl_str_mv |
19345798 |
dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/20.500.12585/8990 |
dc.identifier.doi.none.fl_str_mv |
10.3233/NPM-16814108 |
dc.identifier.instname.none.fl_str_mv |
Universidad Tecnológica de Bolívar |
dc.identifier.reponame.none.fl_str_mv |
Repositorio UTB |
dc.identifier.orcid.none.fl_str_mv |
56461296300 57188743573 57188741911 57188747429 57188737571 53871077300 |
identifier_str_mv |
Journal of Neonatal-Perinatal Medicine; Vol. 9, Núm. 1; pp. 49-57 19345798 10.3233/NPM-16814108 Universidad Tecnológica de Bolívar Repositorio UTB 56461296300 57188743573 57188741911 57188747429 57188737571 53871077300 |
url |
https://hdl.handle.net/20.500.12585/8990 |
dc.language.iso.none.fl_str_mv |
eng |
language |
eng |
dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_16ec |
dc.rights.uri.none.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
dc.rights.accessRights.none.fl_str_mv |
info:eu-repo/semantics/restrictedAccess |
dc.rights.cc.none.fl_str_mv |
Atribución-NoComercial 4.0 Internacional |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ Atribución-NoComercial 4.0 Internacional http://purl.org/coar/access_right/c_16ec |
eu_rights_str_mv |
restrictedAccess |
dc.format.medium.none.fl_str_mv |
Recurso electrónico |
dc.format.mimetype.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
IOS Press |
publisher.none.fl_str_mv |
IOS Press |
dc.source.none.fl_str_mv |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84962629481&doi=10.3233%2fNPM-16814108&partnerID=40&md5=0b4d4daf16fa2a89fd78dd9ade9462d7 |
institution |
Universidad Tecnológica de Bolívar |
bitstream.url.fl_str_mv |
https://repositorio.utb.edu.co/bitstream/20.500.12585/8990/1/MiniProdInv.png |
bitstream.checksum.fl_str_mv |
0cb0f101a8d16897fb46fc914d3d7043 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 |
repository.name.fl_str_mv |
Repositorio Institucional UTB |
repository.mail.fl_str_mv |
repositorioutb@utb.edu.co |
_version_ |
1814021805370769408 |
spelling |
2020-03-26T16:32:43Z2020-03-26T16:32:43Z2016Journal of Neonatal-Perinatal Medicine; Vol. 9, Núm. 1; pp. 49-5719345798https://hdl.handle.net/20.500.12585/899010.3233/NPM-16814108Universidad Tecnológica de BolívarRepositorio UTB564612963005718874357357188741911571887474295718873757153871077300Preeclampsia is associated with abnormalities in the umbilical cord in several ways: morphological, biochemical and functional. Alteration in blood vessels of the placenta, decidua and circulatory system of the fetus might be related to factors that cause preeclampsia and may be associated with alterations of the umbilical cord. OBJECTIVES: This study aimed to analyze the relationship between each type of umbilical cord abnormality and the different subtypes of hypertensive gestational disorders. METHODS: We conducted a prospective study on consecutive autopsies and its placentas, looking for abnormalities in the umbilical cord's features and their clinical associations. RESULTS: Umbilical cord abnormalities including length, diameter, insertion, entanglements, knots and coils were associated with maternal gestational hypertension. CONCLUSION:Inwomen with gestational hypertension, umbilical cord abnormalities are associated with fetal and neonatal consequences. © 2016 IOS Press and the authors.Recurso electrónicoapplication/pdfengIOS Presshttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/restrictedAccessAtribución-NoComercial 4.0 Internacionalhttp://purl.org/coar/access_right/c_16echttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84962629481&doi=10.3233%2fNPM-16814108&partnerID=40&md5=0b4d4daf16fa2a89fd78dd9ade9462d7Umbilical cord and preeclampsiainfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_2df8fbb1EclampsiaGestational hypertensionHELLP syndromePlacentaPregnancyAdultArticleChronic diseaseChronic hypertensionDisease associationEclampsiaEmbryoFemaleFetusHumanHypercoiling umbilical cordHypocoiling umbilical cordMajor clinical studyMaleMarginal umbilical cord insertionMaternal hypertensionParamarginal umbilical cord insertionPreeclampsiaPrematurityPriority journalSingle umbilical arterySuperimposed preeclampsiaUmbilical cordUmbilical malformationAbnormalitiesAutopsyColombiaFetal Growth RetardationFetomaternal transfusionLesions and defectsNewbornPathologyPlacentaPreeclampsiaPregnancyProspective studyVascularizationAdultAutopsyColombiaDilatation, PathologicFemaleFetal Growth RetardationHumansInfant, NewbornMaleMaternal-Fetal ExchangePlacentaPre-EclampsiaPregnancyProspective StudiesUmbilical CordOlaya-C M.Salcedo-Betancourt J.Galvis S.H.Ortiz A.M.Gutierrezb S.Bernal J.E.Sibai, B.M., Diagnosis, prevention, and management of eclampsia (2005) Obstet Gynecol, 105 (2), pp. 402-410Milne, F., Redman, C., Walker, J., Assessing the onset of pre-eclampsia in the hospital day unit: Summary of the pre-eclampsia guideline (PRECOG II) (2000) BMJ, 339, p. 3129Blackburn, W., Umbilical cord (2006) Human Malformation and Related Anomalies, pp. 1413-1495. , Stevenson RE Hall JG. Second edition. New York: Oxford University PressTantbirojn, P., Saleemuddin, A., Sirois, K., Gross abnormalities of the umbilical cord: Related placental histology and clinical significance (2009) Placenta, 30 (12), pp. 1083-1088Horn, L.C., Langner, A., Stiehl, P., Wittekind, C., Faber, R., Identification of the causes of intrauterine death during 310 consecutive autopsies (2004) Eur J Obstet Gynecol Reprod Biol, 113 (2), pp. 134-138Collins, J.H., Collins, C.L., Collins, C.C., Silent risk-Issues about the human umbilical cord (2010) Umbilical Cord Accidents, , http://www.preginst.com/pucp.html, consultado noviembre de 2011Olaya-C, M., Bernal, J.E., Umbilical cord abnormalities in fetal and neonatal pathology in Bogota (2014) Archives of Perinatal Medicine. APM., 20 (1), pp. 22-27Kaplan, C., (2007) Normal Values for Placentas Color Atlas of Gross Placental Pathology, pp. 119-122. , Second edition. New York: SpringerOlaya-C, M., Silva, J.L., Bernal, J.E., Implementation of a simple method to measure total umbilical cord length (2014) J Neonatal Perinatal Med., 7 (4), pp. 269-272Baergen, R.N., (2005) Manual of Benirschke and Kaufmann's Pathology of the Human Placenta, , New York: SpringerPredanic, M., Perni, S., Chasen, S., Baergen, R., Chervenak, F., Ultrasound evaluation of abnormal umbilical cord coiling in second trimester of gestation in association with adverse pregnancy outcome (2005) Am J Obstet Gynecol, 193, pp. 387-394De Laat, M.W., Van Alderen, E.D., Franx, A., Visser, G.H., Bots, M.L., Nikkels, P.G., The umbilical coiling index in complicated pregnanacy (2007) Eur J Obstet Gynecol Reprod Biol, 130, pp. 66-72Gilbert-Barness, E., Debich-Spicer, D., Abnormalities of placenta (2004) Gilbert-Barness e Debich-Spicer D. Embryo and Fetal Pathology, pp. 150-179. , First edition. New York: Cambridge University PressRana, J., Ebert, G.A., Kappy, K.A., Adverse perinatal outcome in patients with an abnormal umbilical coiling index (1995) Obstet Gynecol, 85 (4), pp. 573-577Ezimokhai, M., Rizk, D.E., Thomas, L., Maternal risk factors for abnormal vascular coiling of the umbilical cord (2000) Am J Perinatol, 17 (8), pp. 441-445Baergen, R.N., Malicki, D., Behling, C., Morbidity, mortality, and placental pathology in excessively long umbilical cords: Retrospective study (2001) Pediatr Dev Pathol, 4 (2), pp. 144-153Report of the American College of Obstetricians and Gynecologists' Task Force on hypertension in pregnancy (2013) Obstet Gynecol, 122 (5), pp. 1122-1131. , American College of Obstetricians and GynecologistsTask Force on Hypertension in Pregnancy. Hypertension in pregnancyReport of the national high blood pressure education program working group on high blood pressure in pregnancy (2000) Am J Obstet Gynecol, 183 (1), pp. S1-S22Higgins, J.R., De Swiet, M., Blood-pressure measurement and classification in pregnancy (2001) Lancet, 357 (9250), pp. 131-135Barnard, G.A., Significance tests for 2x2 tables (1947) Biometrika, 34, pp. 123-138Hausman, J.A., McFadden, D., Specification test for the multinomial logit model (1984) Econometrica, 52, pp. 1219-1240A language and environment for statistical computing (2015) R Foundation for Statistical Computing Vienna Austria, , http://www.R-project.org/, R Core Team RHarrell, F.E., Jr., (2015) Harrell Miscellaneous, , http://CRAN.R-project.org/package=Hmisc, R package version 3.16-0Wickham, H., The split-apply-combine strategy for data analysis (2011) J Stat Softw, 40 (1), pp. 1-29Aragon, T.J., (2012) Epitools: Epidemiology Tools, , http://CRAN.R-project.org/package=epitools, R package version 0.5-7Calhoun, P., (2015) Exact: Unconditional Exact Test, , http://CRAN.R-project.org/package=Exact, R package version 1.6Croissant, Y., (2013) Mlogit: Multinomial Logit Model, , http://CRAN.R-project.org/package=mlogit, R package version 0.2-4Leeman, L., Fontaine, P., Hypertensive disorders of pregnancy (2008) Am Fam Physician, 78 (1), pp. 93-100Salazar, J.A., Triana, J.C., Prieto, F.E., Characterising 7 hypertensive disorders during pregnancy inVillavicencio Colombia (2004) Rev Colomb Obstet Ginecol, 55 (4), pp. 279-286Khan, K.S., Wojdyla, D., Say, L., Gulmezoglu, A.M., Van Look, P.F.A., WHO analysis of causes of maternal death: A systematic review (2006) Lancet, 367, pp. 1066-1074Duley, L., The global impact of pre-eclampsia and eclampsia (2009) Semin Perinatol, 33, pp. 130-137Catarino, C., Santos-Silva, A., Belo, L., Inflammatory disturbances in preeclampsia: Relationship between maternal and umbilical cord blood (2012) J Pregnancy, p. 684384Saha, T., Halder, M., Das, A., Das, S.K., Role of nitric oxide, angiogenic growth factors and biochemical analysis in preeclampsia (2013) Indian J Biochem Biophys, 50 (5), pp. 462-466Steegers, E.A., Von Dadelszen, P., Duvekot, J.J., Pijnenborg, R., Pre-eclampsia (2010) Lancet, 376 (9741), pp. 631-644Deng, C.L., Ling, S.T., Liu, X.Q., Zhao, Y.J., Lv, Y.F., Decreased expression of matrix metalloproteinase-1 in the maternal umbilical serum, trophoblasts and decidua leads to preeclampsia (2015) Exp Ther Med, 9 (3), pp. 992-998Inan, S., Sanci, M., Can, D., Vatansever, S., Oztekin, O., Tinar, S., Comparative morphological differences between umbilical cords from chronic hypertensive and preeclamptic pregnancies (2002) Acta Med Okayama., 56 (4), pp. 177-186López-Jaramillo, P., Casas, J.P., Serrano, N., Preeclampsia: From epidemiological observations to molecular mechanisms (2001) Braz J Med Biol Res, 34 (10), pp. 1227-1235Catarino, C., Rebelo, I., Belo, L., Quintanilha, A., Santos-Silva, A., Umbilical Cord Blood Changes in Neonates from A Preeclamptic Pregnancy, from Preconception to Postpartum, , http://www.intechopen.com/books/from-preconception-to-postpartum/umbilical-cord-blood-changes-in-neonates-from-a-preeclamptic-pregnancy, Dr. Stavros Sifakis (Ed.) In: Tech Available from:Blanco, M.V., Vega, H.R., Giuliano, R., Histomorphometry of umbilical cord blood vessels in preeclampsia (2011) J Clin Hypertens (Greenwich), 13 (1), pp. 30-34Masoura, S., Kalogiannidis, I., Makedou, K., Biomarkers of endothelial dysfunction in preeclampsia and neonatal morbidity: A case-control study (2014) Eur J Obstet Gynecol Reprod Biol, 175, pp. 119-123Lam, C., Lim, K.H., Karumanchi, S.A., Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia (2005) Hypertension, 46 (5), pp. 1077-1085Seki, H., The role of the renin-angiotensin system in the pathogenesis of preeclampsia-new insights into the renin-angiotensin system in preeclampsia (2014) Med Hypotheses, 82 (3), pp. 362-367Von Dadelszen, P., Magee, L.A., Pre-eclampsia: An update (2014) Curr Hypertens Rep, 16 (8), p. 454Zhang, Z., Gao, Y., Zhang, L., Alterations of IL-6 IL-6R and gp130 in early and late onset severe preeclampsia (2013) Hypertens Pregnancy, 32 (3), pp. 270-280Tosun, M., Celik, H., Avci, B., Yavuz, E., Alper, T., Malatyalioglu, E., Maternal and umbilical serum levels of interleukin-6, interleukin-8, and tumor necrosis factor-alpha in normal pregnancies and in pregnancies complicated by preeclampsia (2010) J Matern Fetal Neonatal Med, 23 (8), pp. 880-886Romanowicz, L., Bánkowski, E., Sphingolipids of human umbilical cord vein and their alteration in preeclampsia (2010) Mol Cell Biochem, 340 (1-2), pp. 81-89Ferguson, V.L., Dodson, R.B., Bioengineering aspects of the umbilical cord (2009) Eur J Obstet Gynecol Reprod Biol, 144, pp. S108-S113Goynumer, G., Ozdemir, A., Wetherilt, L., Durukan, B., Yayla, M., Umbilical cord thickness in the first and early second trimesters and perinatal outcome (2008) J Perinat Med, 36 (6), pp. 523-526Gogiel, T., Bánkowski, E., Jaworski, S., Pre-eclampsiaassociated differential expression of proteoglycans in the umbilical cord arteries (2001) Pathobiology, 69 (4), pp. 212-218Galewska, Z., Romanowicz, L., Jaworski, S., Matrix metalloproteinase-7 of the umbilical cord in preeclampsia (2008) APM, 14 (2), pp. 41-44Kanter, M., Gurbuz, H., Okman, T.K., Endothelial nitric oxide synthase immunoreactivity and the ultrastructure of endothelial cells of umbilical artery in normal and preeclamptic pregnancies (2010) Clin Exp Hypertens, 32 (7), pp. 458-463Romanowicz, L., Galewska, Z., Extracellular matrix remodeling of the umbilical cord in pre-eclampsia as a risk factor for fetal hypertension (2011) J Pregnancy, 2011, p. 542695Redman, C.W., Hypertension in pregnancy: The NICE guidelines (2011) Heart, 97 (23), pp. 1967-1969http://purl.org/coar/resource_type/c_6501THUMBNAILMiniProdInv.pngMiniProdInv.pngimage/png23941https://repositorio.utb.edu.co/bitstream/20.500.12585/8990/1/MiniProdInv.png0cb0f101a8d16897fb46fc914d3d7043MD5120.500.12585/8990oai:repositorio.utb.edu.co:20.500.12585/89902021-02-02 14:21:56.021Repositorio Institucional UTBrepositorioutb@utb.edu.co |