Need for caution in the diagnosis of radiation pneumonitis during the COVID-19 pandemic
Purpose: Patients with cancer are at high risk for mortality from coronavirus disease 2019 (COVID-19). Radiation pneumonitis (RP) is a common toxicity of thoracic radiation therapy with clinical and imaging features that overlap with those of COVID-19; however, RP is treated with high-dose corticost...
- Autores:
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2020
- Institución:
- Universidad de Bogotá Jorge Tadeo Lozano
- Repositorio:
- Expeditio: repositorio UTadeo
- Idioma:
- eng
- OAI Identifier:
- oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/13816
- Acceso en línea:
- https://doi.org/10.1016/j.adro.2020.04.015
http://hdl.handle.net/20.500.12010/13816
- Palabra clave:
- COVID-19
Diagnosis of radiation pneumonitis
Pandemic
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
- Rights
- License
- Abierto (Texto Completo)
id |
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oai_identifier_str |
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/13816 |
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UTADEO2 |
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Expeditio: repositorio UTadeo |
repository_id_str |
|
dc.title.spa.fl_str_mv |
Need for caution in the diagnosis of radiation pneumonitis during the COVID-19 pandemic |
title |
Need for caution in the diagnosis of radiation pneumonitis during the COVID-19 pandemic |
spellingShingle |
Need for caution in the diagnosis of radiation pneumonitis during the COVID-19 pandemic COVID-19 Diagnosis of radiation pneumonitis Pandemic Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
title_short |
Need for caution in the diagnosis of radiation pneumonitis during the COVID-19 pandemic |
title_full |
Need for caution in the diagnosis of radiation pneumonitis during the COVID-19 pandemic |
title_fullStr |
Need for caution in the diagnosis of radiation pneumonitis during the COVID-19 pandemic |
title_full_unstemmed |
Need for caution in the diagnosis of radiation pneumonitis during the COVID-19 pandemic |
title_sort |
Need for caution in the diagnosis of radiation pneumonitis during the COVID-19 pandemic |
dc.subject.spa.fl_str_mv |
COVID-19 Diagnosis of radiation pneumonitis Pandemic |
topic |
COVID-19 Diagnosis of radiation pneumonitis Pandemic Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
dc.subject.lemb.spa.fl_str_mv |
Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
description |
Purpose: Patients with cancer are at high risk for mortality from coronavirus disease 2019 (COVID-19). Radiation pneumonitis (RP) is a common toxicity of thoracic radiation therapy with clinical and imaging features that overlap with those of COVID-19; however, RP is treated with high-dose corticosteroids, which may exacerbate COVID-19eassociated lung injury. We reviewed patients who presented with symptoms of RP during the intensification of a regional COVID-19 epidemic to report on their clinical course and COVID-19 testing results. Methods and Materials: The clinical course and chest computed tomography (CT) imaging findings of consecutive patients who presented with symptoms of RP in March 2020 were reviewed. The first regional COVID-19 case was diagnosed on March 1, 2020. All patients underwent COVID-19 qualitative RNA testing. Results: Four patients with clinical suspicion for RP were assessed. Three out of 4 patients tested positive for COVID-19. All patients presented with symptoms of cough and dyspnea. Two patients had a fever, of whom only 1 tested positive for COVID-19. Two patients started on an empirical high-dose corticosteroid taper for presumed RP, but both had clinical deterioration and ultimately tested positive for COVID-19 and required hospitalization. Chest CT findings in patients suspected of RP but ultimately diagnosed with COVID-19 showed ground-glass opacities mostly pronounced outside the radiation field. Conclusions: As this pandemic continues, patients with symptoms of RP require diagnostic attention. We recommend that patients suspected of RP be tested for COVID-19 before starting empirical corticosteroids and for careful attention to be paid to chest CT imaging to prevent potential exacerbation of COVID-19 in these high-risk patients. |
publishDate |
2020 |
dc.date.accessioned.none.fl_str_mv |
2020-09-25T17:33:29Z |
dc.date.available.none.fl_str_mv |
2020-09-25T17:33:29Z |
dc.date.created.none.fl_str_mv |
2020 |
dc.type.local.spa.fl_str_mv |
Artículo |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
format |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.identifier.issn.spa.fl_str_mv |
2452-1094 |
dc.identifier.other.spa.fl_str_mv |
https://doi.org/10.1016/j.adro.2020.04.015 |
dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/20.500.12010/13816 |
dc.identifier.doi.spa.fl_str_mv |
https://doi.org/10.1016/j.adro.2020.04.015 |
identifier_str_mv |
2452-1094 |
url |
https://doi.org/10.1016/j.adro.2020.04.015 http://hdl.handle.net/20.500.12010/13816 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.rights.local.spa.fl_str_mv |
Abierto (Texto Completo) |
rights_invalid_str_mv |
Abierto (Texto Completo) http://purl.org/coar/access_right/c_abf2 |
dc.format.extent.spa.fl_str_mv |
4 páginas |
dc.format.mimetype.spa.fl_str_mv |
application/pdf |
dc.publisher.spa.fl_str_mv |
Advances in Radiation Oncology |
dc.source.spa.fl_str_mv |
reponame:Expeditio Repositorio Institucional UJTL instname:Universidad de Bogotá Jorge Tadeo Lozano |
instname_str |
Universidad de Bogotá Jorge Tadeo Lozano |
institution |
Universidad de Bogotá Jorge Tadeo Lozano |
reponame_str |
Expeditio Repositorio Institucional UJTL |
collection |
Expeditio Repositorio Institucional UJTL |
bitstream.url.fl_str_mv |
https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/13816/1/Need-for-Caution-in-the-Diagnosis-of-Radiation-Pneumo_2020_Advances-in-Radia.pdf https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/13816/2/license.txt https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/13816/3/Need-for-Caution-in-the-Diagnosis-of-Radiation-Pneumo_2020_Advances-in-Radia.pdf.jpg |
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bitstream.checksumAlgorithm.fl_str_mv |
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repository.name.fl_str_mv |
Repositorio Institucional - Universidad Jorge Tadeo Lozano |
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spelling |
2020-09-25T17:33:29Z2020-09-25T17:33:29Z20202452-1094https://doi.org/10.1016/j.adro.2020.04.015http://hdl.handle.net/20.500.12010/13816https://doi.org/10.1016/j.adro.2020.04.015Purpose: Patients with cancer are at high risk for mortality from coronavirus disease 2019 (COVID-19). Radiation pneumonitis (RP) is a common toxicity of thoracic radiation therapy with clinical and imaging features that overlap with those of COVID-19; however, RP is treated with high-dose corticosteroids, which may exacerbate COVID-19eassociated lung injury. We reviewed patients who presented with symptoms of RP during the intensification of a regional COVID-19 epidemic to report on their clinical course and COVID-19 testing results. Methods and Materials: The clinical course and chest computed tomography (CT) imaging findings of consecutive patients who presented with symptoms of RP in March 2020 were reviewed. The first regional COVID-19 case was diagnosed on March 1, 2020. All patients underwent COVID-19 qualitative RNA testing. Results: Four patients with clinical suspicion for RP were assessed. Three out of 4 patients tested positive for COVID-19. All patients presented with symptoms of cough and dyspnea. Two patients had a fever, of whom only 1 tested positive for COVID-19. Two patients started on an empirical high-dose corticosteroid taper for presumed RP, but both had clinical deterioration and ultimately tested positive for COVID-19 and required hospitalization. Chest CT findings in patients suspected of RP but ultimately diagnosed with COVID-19 showed ground-glass opacities mostly pronounced outside the radiation field. Conclusions: As this pandemic continues, patients with symptoms of RP require diagnostic attention. We recommend that patients suspected of RP be tested for COVID-19 before starting empirical corticosteroids and for careful attention to be paid to chest CT imaging to prevent potential exacerbation of COVID-19 in these high-risk patients.4 páginasapplication/pdfengAdvances in Radiation Oncologyreponame:Expeditio Repositorio Institucional UJTLinstname:Universidad de Bogotá Jorge Tadeo LozanoCOVID-19Diagnosis of radiation pneumonitisPandemicSíndrome respiratorio agudo graveCOVID-19SARS-CoV-2CoronavirusNeed for caution in the diagnosis of radiation pneumonitis during the COVID-19 pandemicArtículohttp://purl.org/coar/resource_type/c_2df8fbb1Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2Shaverdian, NarekShepherd, Annemarie F.Rimner, AndreasWu, Abraham J.Simone II, Charles B.Gelblum, Daphna Y.Daniel R. GomezORIGINALNeed-for-Caution-in-the-Diagnosis-of-Radiation-Pneumo_2020_Advances-in-Radia.pdfNeed-for-Caution-in-the-Diagnosis-of-Radiation-Pneumo_2020_Advances-in-Radia.pdfVer artículoapplication/pdf715222https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/13816/1/Need-for-Caution-in-the-Diagnosis-of-Radiation-Pneumo_2020_Advances-in-Radia.pdf22aa1b5565c7f58d93509d915bfd9d4bMD51open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-82938https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/13816/2/license.txtabceeb1c943c50d3343516f9dbfc110fMD52open accessTHUMBNAILNeed-for-Caution-in-the-Diagnosis-of-Radiation-Pneumo_2020_Advances-in-Radia.pdf.jpgNeed-for-Caution-in-the-Diagnosis-of-Radiation-Pneumo_2020_Advances-in-Radia.pdf.jpgIM Thumbnailimage/jpeg22744https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/13816/3/Need-for-Caution-in-the-Diagnosis-of-Radiation-Pneumo_2020_Advances-in-Radia.pdf.jpg6ab214685a28f4226b703315fad99c4fMD53open access20.500.12010/13816oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/138162020-09-25 12:33:29.573open accessRepositorio Institucional - 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