Advancements in the co-formulation of biologic therapeutics
Biologic therapeutics are the medicines of the future and are destined to transform the approaches by which the causes and symptoms of diseases are cured and alleviated. These approaches will be accelerated through the development of novel strategies that target multiple pharmacologically active sit...
- Autores:
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2020
- Institución:
- Universidad de Bogotá Jorge Tadeo Lozano
- Repositorio:
- Expeditio: repositorio UTadeo
- Idioma:
- eng
- OAI Identifier:
- oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12585
- Acceso en línea:
- https://doi.org/10.1016/j.jconrel.2020.08.013
http://hdl.handle.net/20.500.12010/12585
- Palabra clave:
- Targeted
Biologic
Co-formulation
Active pharmaceutical ingredients
Proteins
Nucleic acids
Vaccines
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
- Rights
- License
- Acceso restringido
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| dc.title.spa.fl_str_mv |
Advancements in the co-formulation of biologic therapeutics |
| title |
Advancements in the co-formulation of biologic therapeutics |
| spellingShingle |
Advancements in the co-formulation of biologic therapeutics Targeted Biologic Co-formulation Active pharmaceutical ingredients Proteins Nucleic acids Vaccines Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
| title_short |
Advancements in the co-formulation of biologic therapeutics |
| title_full |
Advancements in the co-formulation of biologic therapeutics |
| title_fullStr |
Advancements in the co-formulation of biologic therapeutics |
| title_full_unstemmed |
Advancements in the co-formulation of biologic therapeutics |
| title_sort |
Advancements in the co-formulation of biologic therapeutics |
| dc.subject.spa.fl_str_mv |
Targeted Biologic Co-formulation Active pharmaceutical ingredients Proteins Nucleic acids Vaccines |
| topic |
Targeted Biologic Co-formulation Active pharmaceutical ingredients Proteins Nucleic acids Vaccines Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
| dc.subject.lemb.spa.fl_str_mv |
Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
| description |
Biologic therapeutics are the medicines of the future and are destined to transform the approaches by which the causes and symptoms of diseases are cured and alleviated. These approaches will be accelerated through the development of novel strategies that target multiple pharmacologically active sites using a combination of different biologics, or mixtures of biologics and small molecule therapeutics. However, for this potential to be realised, advancements in co-formulation strategies for biologic therapeutics must be established. This review describes the current and emerging developments within this field and highlights the challenges and potential solutions, that will pavethe-way towards their clinical translation. |
| publishDate |
2020 |
| dc.date.accessioned.none.fl_str_mv |
2020-09-02T14:49:33Z |
| dc.date.available.none.fl_str_mv |
2020-09-02T14:49:33Z |
| dc.date.created.none.fl_str_mv |
2020 |
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Artículo |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.identifier.issn.spa.fl_str_mv |
0168-3659 |
| dc.identifier.other.spa.fl_str_mv |
https://doi.org/10.1016/j.jconrel.2020.08.013 |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/20.500.12010/12585 |
| dc.identifier.doi.spa.fl_str_mv |
https://doi.org/10.1016/j.jconrel.2020.08.013 |
| identifier_str_mv |
0168-3659 |
| url |
https://doi.org/10.1016/j.jconrel.2020.08.013 http://hdl.handle.net/20.500.12010/12585 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
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http://purl.org/coar/access_right/c_f1cf |
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Acceso restringido |
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Acceso restringido http://purl.org/coar/access_right/c_f1cf |
| dc.format.extent.spa.fl_str_mv |
23 páginas |
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image/jepg |
| dc.publisher.spa.fl_str_mv |
Journal of Controlled Release |
| dc.source.spa.fl_str_mv |
reponame:Expeditio Repositorio Institucional UJTL instname:Universidad de Bogotá Jorge Tadeo Lozano |
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Universidad de Bogotá Jorge Tadeo Lozano |
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2020-09-02T14:49:33Z2020-09-02T14:49:33Z20200168-3659https://doi.org/10.1016/j.jconrel.2020.08.013http://hdl.handle.net/20.500.12010/12585https://doi.org/10.1016/j.jconrel.2020.08.013Biologic therapeutics are the medicines of the future and are destined to transform the approaches by which the causes and symptoms of diseases are cured and alleviated. These approaches will be accelerated through the development of novel strategies that target multiple pharmacologically active sites using a combination of different biologics, or mixtures of biologics and small molecule therapeutics. However, for this potential to be realised, advancements in co-formulation strategies for biologic therapeutics must be established. This review describes the current and emerging developments within this field and highlights the challenges and potential solutions, that will pavethe-way towards their clinical translation.23 páginasimage/jepgengJournal of Controlled Releasereponame:Expeditio Repositorio Institucional UJTLinstname:Universidad de Bogotá Jorge Tadeo LozanoTargetedBiologicCo-formulationActive pharmaceutical ingredientsProteinsNucleic acidsVaccinesSíndrome respiratorio agudo graveCOVID-19SARS-CoV-2CoronavirusAdvancements in the co-formulation of biologic therapeuticsArtículohttp://purl.org/coar/resource_type/c_2df8fbb1Acceso restringidohttp://purl.org/coar/access_right/c_f1cfChauhan, Veeren M.Zhang, HongyuDalby, Paul A.Aylott, Jonathan W.THUMBNAILCaptura.PNGCaptura.PNGPortadaimage/png83203https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12585/4/Captura.PNGce89acf0b6e88256ec4ee2098444d060MD54open accessAdvancements-in-the-co-formulation-of-biologic-_2020_Journal-of-Controlled-R.pdf.jpgAdvancements-in-the-co-formulation-of-biologic-_2020_Journal-of-Controlled-R.pdf.jpgIM Thumbnailimage/jpeg10383https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12585/5/Advancements-in-the-co-formulation-of-biologic-_2020_Journal-of-Controlled-R.pdf.jpge2c24c0ca4232b6c6f69ed9d48e277c9MD55open accessORIGINALCaptura.PNGCaptura.PNGVer portadaimage/png83203https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12585/1/Captura.PNGce89acf0b6e88256ec4ee2098444d060MD51open accessAdvancements-in-the-co-formulation-of-biologic-_2020_Journal-of-Controlled-R.pdfAdvancements-in-the-co-formulation-of-biologic-_2020_Journal-of-Controlled-R.pdfArtículo reservadoapplication/pdf733678https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12585/3/Advancements-in-the-co-formulation-of-biologic-_2020_Journal-of-Controlled-R.pdf8535a1db8e184d2f498050222b86c5a0MD53embargoed access|||2200-09-02LICENSElicense.txtlicense.txttext/plain; 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