Admission high-sensitivity cardiac troponin versus a biochemical score for predicting mortality in patients with COVID-19

Emerging evidence indicates a role for cardiac troponin testing, specifically high-sensitivity cardiac troponin (hs-cTn) in hospitalized patients with COVID-19(1). Undetectable levels of hscTn in patients with (and without) COVID-19 may be helpful in identifying a low-risk subgroup, with higher leve...

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Autores:
Tipo de recurso:
Article of investigation
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/14596
Acceso en línea:
https://doi.org/10.1016/j.cjco.2020.10.008
http://hdl.handle.net/20.500.12010/14596
Palabra clave:
Predicting mortality
COVID-19
High-sensitivity cardiac troponin
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
Rights
License
Abierto (Texto Completo)
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dc.title.spa.fl_str_mv Admission high-sensitivity cardiac troponin versus a biochemical score for predicting mortality in patients with COVID-19
title Admission high-sensitivity cardiac troponin versus a biochemical score for predicting mortality in patients with COVID-19
spellingShingle Admission high-sensitivity cardiac troponin versus a biochemical score for predicting mortality in patients with COVID-19
Predicting mortality
COVID-19
High-sensitivity cardiac troponin
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
title_short Admission high-sensitivity cardiac troponin versus a biochemical score for predicting mortality in patients with COVID-19
title_full Admission high-sensitivity cardiac troponin versus a biochemical score for predicting mortality in patients with COVID-19
title_fullStr Admission high-sensitivity cardiac troponin versus a biochemical score for predicting mortality in patients with COVID-19
title_full_unstemmed Admission high-sensitivity cardiac troponin versus a biochemical score for predicting mortality in patients with COVID-19
title_sort Admission high-sensitivity cardiac troponin versus a biochemical score for predicting mortality in patients with COVID-19
dc.subject.spa.fl_str_mv Predicting mortality
COVID-19
High-sensitivity cardiac troponin
topic Predicting mortality
COVID-19
High-sensitivity cardiac troponin
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
dc.subject.lemb.spa.fl_str_mv Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
description Emerging evidence indicates a role for cardiac troponin testing, specifically high-sensitivity cardiac troponin (hs-cTn) in hospitalized patients with COVID-19(1). Undetectable levels of hscTn in patients with (and without) COVID-19 may be helpful in identifying a low-risk subgroup, with higher levels useful in identifying patients at high-risk for hospital death(1,2). Further improvements in risk-stratification for emergency department or hospitalized patients may be achieved by adding clinical chemistry tests, such as glucose and creatinine [i.e., estimated glomerular filtration rate (eGFR)] to generate a clinical chemistry score (CCS)(2,3). For patients with COVID-19, additional biochemical tests may have important prognostic roles such as urea which is already a component of the CURB-65 score (confusion, urea, respiratory rate, blood pressure, age ≥65y) used to risk stratify patients presenting to hospital with pneumonia(4). We performed a retrospective chart review of COVID-19 patients admitted to hospitals in the city of Hamilton in order to explore the performance characteristics of hs-cTn levels, the CCS and the CCS with urea (CCUS) to predict in-hospital death. This review included the first 26-weeks of this pandemic (ethics-approval:#11425-C).
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-10-19T20:34:41Z
dc.date.available.none.fl_str_mv 2020-10-19T20:34:41Z
dc.date.created.none.fl_str_mv 2020
dc.type.local.spa.fl_str_mv Artículo
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
format http://purl.org/coar/resource_type/c_2df8fbb1
dc.identifier.issn.spa.fl_str_mv 2589-790X
dc.identifier.other.spa.fl_str_mv https://doi.org/10.1016/j.cjco.2020.10.008
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12010/14596
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1016/j.cjco.2020.10.008
identifier_str_mv 2589-790X
url https://doi.org/10.1016/j.cjco.2020.10.008
http://hdl.handle.net/20.500.12010/14596
dc.language.iso.spa.fl_str_mv eng
language eng
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.local.spa.fl_str_mv Abierto (Texto Completo)
rights_invalid_str_mv Abierto (Texto Completo)
http://purl.org/coar/access_right/c_abf2
dc.format.extent.spa.fl_str_mv 7 páginas
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv CJC Open
dc.source.spa.fl_str_mv reponame:Expeditio Repositorio Institucional UJTL
instname:Universidad de Bogotá Jorge Tadeo Lozano
instname_str Universidad de Bogotá Jorge Tadeo Lozano
institution Universidad de Bogotá Jorge Tadeo Lozano
reponame_str Expeditio Repositorio Institucional UJTL
collection Expeditio Repositorio Institucional UJTL
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spelling 2020-10-19T20:34:41Z2020-10-19T20:34:41Z20202589-790Xhttps://doi.org/10.1016/j.cjco.2020.10.008http://hdl.handle.net/20.500.12010/14596https://doi.org/10.1016/j.cjco.2020.10.008Emerging evidence indicates a role for cardiac troponin testing, specifically high-sensitivity cardiac troponin (hs-cTn) in hospitalized patients with COVID-19(1). Undetectable levels of hscTn in patients with (and without) COVID-19 may be helpful in identifying a low-risk subgroup, with higher levels useful in identifying patients at high-risk for hospital death(1,2). Further improvements in risk-stratification for emergency department or hospitalized patients may be achieved by adding clinical chemistry tests, such as glucose and creatinine [i.e., estimated glomerular filtration rate (eGFR)] to generate a clinical chemistry score (CCS)(2,3). For patients with COVID-19, additional biochemical tests may have important prognostic roles such as urea which is already a component of the CURB-65 score (confusion, urea, respiratory rate, blood pressure, age ≥65y) used to risk stratify patients presenting to hospital with pneumonia(4). We performed a retrospective chart review of COVID-19 patients admitted to hospitals in the city of Hamilton in order to explore the performance characteristics of hs-cTn levels, the CCS and the CCS with urea (CCUS) to predict in-hospital death. This review included the first 26-weeks of this pandemic (ethics-approval:#11425-C).7 páginasapplication/pdfengCJC Openreponame:Expeditio Repositorio Institucional UJTLinstname:Universidad de Bogotá Jorge Tadeo LozanoPredicting mortalityCOVID-19High-sensitivity cardiac troponinSíndrome respiratorio agudo graveCOVID-19SARS-CoV-2CoronavirusAdmission high-sensitivity cardiac troponin versus a biochemical score for predicting mortality in patients with COVID-19Artículohttp://purl.org/coar/resource_type/c_2df8fbb1Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2Kavsak, Peter A.Mondoux, Shawn E.Wit, Kerstin deRochwerg, BramMain, CherylYamamura, DeborahParé, GuillaumeMa, JinhuiPerri, DanSherbino, JonathanWorster, AndrewTHUMBNAILAdmission-high-sensitivity-cardiac-troponin-versus-a-biochemical-s_2020_CJC-.pdf.jpgAdmission-high-sensitivity-cardiac-troponin-versus-a-biochemical-s_2020_CJC-.pdf.jpgIM Thumbnailimage/jpeg10869https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14596/3/Admission-high-sensitivity-cardiac-troponin-versus-a-biochemical-s_2020_CJC-.pdf.jpgcc3156744062e0e00e137ef795bb02cdMD53open accessLICENSElicense.txtlicense.txttext/plain; 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