Comparative studies between HTLV-1 and HTLV-2 function and pathobiology
Human T-cell leukemia viruses type 1 and 2 (HTLV-1 and HTLV-2) share a common genetic organization, expression strategy and ability to infect and immortalize T-cells in vitro; however, HTLV-1 and HTLV-2 are strikingly different in terms of clinical impact. HTLV-1 is recognized as the aetiological ag...
- Autores:
- Tipo de recurso:
- Book
- Fecha de publicación:
- 2015
- Institución:
- Universidad de Bogotá Jorge Tadeo Lozano
- Repositorio:
- Expeditio: repositorio UTadeo
- Idioma:
- eng
- OAI Identifier:
- oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/14390
- Acceso en línea:
- https://www.frontiersin.org/research-topics/1265/comparative-studies-between-htlv-1-and-htlv-2-function-and-pathobiology
http://hdl.handle.net/20.500.12010/14390
- Palabra clave:
- Ciencia
Microbiología
Proteínas
Función HTLV-1 y HTLV-2
- Rights
- License
- Abierto (Texto Completo)
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| dc.title.spa.fl_str_mv |
Comparative studies between HTLV-1 and HTLV-2 function and pathobiology |
| title |
Comparative studies between HTLV-1 and HTLV-2 function and pathobiology |
| spellingShingle |
Comparative studies between HTLV-1 and HTLV-2 function and pathobiology Ciencia Microbiología Proteínas Función HTLV-1 y HTLV-2 |
| title_short |
Comparative studies between HTLV-1 and HTLV-2 function and pathobiology |
| title_full |
Comparative studies between HTLV-1 and HTLV-2 function and pathobiology |
| title_fullStr |
Comparative studies between HTLV-1 and HTLV-2 function and pathobiology |
| title_full_unstemmed |
Comparative studies between HTLV-1 and HTLV-2 function and pathobiology |
| title_sort |
Comparative studies between HTLV-1 and HTLV-2 function and pathobiology |
| dc.subject.spa.fl_str_mv |
Ciencia |
| topic |
Ciencia Microbiología Proteínas Función HTLV-1 y HTLV-2 |
| dc.subject.lemb.spa.fl_str_mv |
Microbiología Proteínas Función HTLV-1 y HTLV-2 |
| description |
Human T-cell leukemia viruses type 1 and 2 (HTLV-1 and HTLV-2) share a common genetic organization, expression strategy and ability to infect and immortalize T-cells in vitro; however, HTLV-1 and HTLV-2 are strikingly different in terms of clinical impact. HTLV-1 is recognized as the aetiological agent of adult T-cell leukemia/lymphoma (ATLL), and HTLV-associated myeolopathy/tropical spastic paraparesis (HAM/TSP), in contrast, HTLV-2 does not cause hematologic disorders and is only sporadically associated with cases of subacute myelopathy. HTLV-1 and HTLV-2 also exhibit distinct cellular tropisms in vivo: HTLV-1 is mainly found in CD4+T lymphocytes, whereas CD8+T-cells are the preferred target for HTLV-2. The articles contributed in this Research Topic are covering all the different aspects that characterize HTLV-1 and HTLV-2, by highlighting differences in their biology that might provide clues to their distinct pathogenic properties. |
| publishDate |
2015 |
| dc.date.created.none.fl_str_mv |
2015-11-16 |
| dc.date.accessioned.none.fl_str_mv |
2020-10-13T16:46:24Z |
| dc.date.available.none.fl_str_mv |
2020-10-13T16:46:24Z |
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Libro |
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http://purl.org/coar/resource_type/c_2f33 |
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http://purl.org/coar/resource_type/c_2f33 |
| dc.identifier.isbn.none.fl_str_mv |
978-2-889-19498-8 |
| dc.identifier.issn.none.fl_str_mv |
1664-8714 |
| dc.identifier.other.none.fl_str_mv |
https://www.frontiersin.org/research-topics/1265/comparative-studies-between-htlv-1-and-htlv-2-function-and-pathobiology |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/20.500.12010/14390 |
| dc.identifier.doi.none.fl_str_mv |
10.3389/978-2-88919-498-8 |
| identifier_str_mv |
978-2-889-19498-8 1664-8714 10.3389/978-2-88919-498-8 |
| url |
https://www.frontiersin.org/research-topics/1265/comparative-studies-between-htlv-1-and-htlv-2-function-and-pathobiology http://hdl.handle.net/20.500.12010/14390 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.references.spa.fl_str_mv |
Bertazzoni U (2015) Editorial to the Research Topic “Comparative studies between HTLV-1 and HTLV-2 function and pathobiology”. Front. Microbiol. 5:792. doi: 10.3389/fmicb.2014.00792 |
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http://purl.org/coar/access_right/c_abf2 |
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Abierto (Texto Completo) |
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https://creativecommons.org/licenses/by/4.0/legalcode |
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Abierto (Texto Completo) https://creativecommons.org/licenses/by/4.0/legalcode http://purl.org/coar/access_right/c_abf2 |
| dc.format.extent.spa.fl_str_mv |
95 páginas |
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application/pdf |
| dc.publisher.spa.fl_str_mv |
Frontiers Media SA |
| institution |
Universidad de Bogotá Jorge Tadeo Lozano |
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2020-10-13T16:46:24Z2020-10-13T16:46:24Z2015-11-16978-2-889-19498-81664-8714https://www.frontiersin.org/research-topics/1265/comparative-studies-between-htlv-1-and-htlv-2-function-and-pathobiologyhttp://hdl.handle.net/20.500.12010/1439010.3389/978-2-88919-498-895 páginasapplication/pdfengFrontiers Media SACienciaMicrobiologíaProteínasFunción HTLV-1 y HTLV-2Comparative studies between HTLV-1 and HTLV-2 function and pathobiologyLibrohttp://purl.org/coar/resource_type/c_2f33Abierto (Texto Completo)https://creativecommons.org/licenses/by/4.0/legalcodehttp://purl.org/coar/access_right/c_abf2Bertazzoni U (2015) Editorial to the Research Topic “Comparative studies between HTLV-1 and HTLV-2 function and pathobiology”. Front. Microbiol. 5:792. doi: 10.3389/fmicb.2014.00792Human T-cell leukemia viruses type 1 and 2 (HTLV-1 and HTLV-2) share a common genetic organization, expression strategy and ability to infect and immortalize T-cells in vitro; however, HTLV-1 and HTLV-2 are strikingly different in terms of clinical impact. HTLV-1 is recognized as the aetiological agent of adult T-cell leukemia/lymphoma (ATLL), and HTLV-associated myeolopathy/tropical spastic paraparesis (HAM/TSP), in contrast, HTLV-2 does not cause hematologic disorders and is only sporadically associated with cases of subacute myelopathy. HTLV-1 and HTLV-2 also exhibit distinct cellular tropisms in vivo: HTLV-1 is mainly found in CD4+T lymphocytes, whereas CD8+T-cells are the preferred target for HTLV-2. The articles contributed in this Research Topic are covering all the different aspects that characterize HTLV-1 and HTLV-2, by highlighting differences in their biology that might provide clues to their distinct pathogenic properties.Bertazzoni, UmbertoBex, FrançoiseLICENSElicense.txtlicense.txttext/plain; charset=utf-82938https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14390/2/license.txtabceeb1c943c50d3343516f9dbfc110fMD52open accessORIGINALComparative Studies Between HTLV-1 and HTLV-2 Function and Pathobiology_58.PDFComparative Studies Between HTLV-1 and HTLV-2 Function and Pathobiology_58.PDFVer documentoapplication/pdf13300924https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14390/1/Comparative%20Studies%20Between%20HTLV-1%20and%20HTLV-2%20Function%20and%20Pathobiology_58.PDF7d7b7618beb1c72f8ad8a3a66fe2937dMD51open accessTHUMBNAILComparative Studies Between HTLV-1 and HTLV-2 Function and Pathobiology_58.PDF.jpgComparative Studies Between HTLV-1 and HTLV-2 Function and Pathobiology_58.PDF.jpgIM Thumbnailimage/jpeg20920https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14390/3/Comparative%20Studies%20Between%20HTLV-1%20and%20HTLV-2%20Function%20and%20Pathobiology_58.PDF.jpg46a006cd72e35f14a37f6022c52565a7MD53open access20.500.12010/14390oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/143902021-01-21 18:19:17.704open accessRepositorio Institucional - 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