Overview of the current promising approaches for the development of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine

Coronavirus disease 2019 (COVID-19) is a pandemic infectious disease caused by the novel coronavirus called SARS-CoV-2. There is a gap in our understanding regarding the immunopathogenesis of COVID-19. However, many clinical trials are underway across the world for screening effective drugs against...

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Autores:
Tipo de recurso:
Article of journal
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/13211
Acceso en línea:
https://www.sciencedirect.com/science/article/pii/S1567576920320464?via%3Dihub
http://hdl.handle.net/20.500.12010/13211
https://doi.org/10.1016/j.intimp.2020.106928
Palabra clave:
COVID-19
SARS-CoV-2
Immunopathogenesis
Vaccines
Rights
License
Acceso restringido
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oai_identifier_str oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/13211
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dc.title.spa.fl_str_mv Overview of the current promising approaches for the development of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine
title Overview of the current promising approaches for the development of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine
spellingShingle Overview of the current promising approaches for the development of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine
COVID-19
SARS-CoV-2
Immunopathogenesis
Vaccines
title_short Overview of the current promising approaches for the development of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine
title_full Overview of the current promising approaches for the development of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine
title_fullStr Overview of the current promising approaches for the development of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine
title_full_unstemmed Overview of the current promising approaches for the development of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine
title_sort Overview of the current promising approaches for the development of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine
dc.subject.spa.fl_str_mv COVID-19
topic COVID-19
SARS-CoV-2
Immunopathogenesis
Vaccines
dc.subject.keyword.spa.fl_str_mv SARS-CoV-2
Immunopathogenesis
Vaccines
description Coronavirus disease 2019 (COVID-19) is a pandemic infectious disease caused by the novel coronavirus called SARS-CoV-2. There is a gap in our understanding regarding the immunopathogenesis of COVID-19. However, many clinical trials are underway across the world for screening effective drugs against COVID-19. Nevertheless, currently, no proven effective therapies for this virus exists. The vaccines are deemed as a significant part of disease prevention for emerging viral diseases, since, in several cases, other therapeutic choices are limited or non‐existent, or that diseases result in such an accelerated clinical worsening that the efficacy of treatments is restricted. Therefore, effective vaccines against COVID-19 are urgently required to overcome the tremendous burden of mortality and morbidity correlated with SARS-CoV-2. In this review, we will describe the latest evidence regarding outstanding vaccine approaches and the challenges for vaccine production.
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-09-12T15:13:17Z
dc.date.available.none.fl_str_mv 2020-09-12T15:13:17Z
dc.date.created.none.fl_str_mv 2020-11
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_6501
format http://purl.org/coar/resource_type/c_6501
dc.identifier.issn.spa.fl_str_mv 1567-5769
dc.identifier.other.spa.fl_str_mv https://www.sciencedirect.com/science/article/pii/S1567576920320464?via%3Dihub
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12010/13211
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1016/j.intimp.2020.106928
identifier_str_mv 1567-5769
url https://www.sciencedirect.com/science/article/pii/S1567576920320464?via%3Dihub
http://hdl.handle.net/20.500.12010/13211
https://doi.org/10.1016/j.intimp.2020.106928
dc.language.iso.spa.fl_str_mv eng
language eng
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_f1cf
dc.rights.local.spa.fl_str_mv Acceso restringido
rights_invalid_str_mv Acceso restringido
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dc.format.extent.spa.fl_str_mv 14 páginas
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv International Immunopharmacology
institution Universidad de Bogotá Jorge Tadeo Lozano
bitstream.url.fl_str_mv https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/13211/2/license.txt
https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/13211/3/Overview-of-the-current-promising-approaches-for-the-devel_2020_Internationa.pdf
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spelling 2020-09-12T15:13:17Z2020-09-12T15:13:17Z2020-111567-5769https://www.sciencedirect.com/science/article/pii/S1567576920320464?via%3Dihubhttp://hdl.handle.net/20.500.12010/13211https://doi.org/10.1016/j.intimp.2020.10692814 páginasapplication/pdfengInternational ImmunopharmacologyCOVID-19SARS-CoV-2ImmunopathogenesisVaccinesOverview of the current promising approaches for the development of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccineAcceso restringidohttp://purl.org/coar/access_right/c_f1cfCoronavirus disease 2019 (COVID-19) is a pandemic infectious disease caused by the novel coronavirus called SARS-CoV-2. There is a gap in our understanding regarding the immunopathogenesis of COVID-19. However, many clinical trials are underway across the world for screening effective drugs against COVID-19. Nevertheless, currently, no proven effective therapies for this virus exists. The vaccines are deemed as a significant part of disease prevention for emerging viral diseases, since, in several cases, other therapeutic choices are limited or non‐existent, or that diseases result in such an accelerated clinical worsening that the efficacy of treatments is restricted. Therefore, effective vaccines against COVID-19 are urgently required to overcome the tremendous burden of mortality and morbidity correlated with SARS-CoV-2. In this review, we will describe the latest evidence regarding outstanding vaccine approaches and the challenges for vaccine production.http://purl.org/coar/resource_type/c_6501Mirzaei, RasoulMohammadzadeh, RokhsarehMahdavi, FarzadBadrzadeh, FaribaKazemi, SheidaEbrahimi, MehdiSoltani, FatemehKazemi, SimaSalimi Jeda, AliDarvishmotevalli, MohammadYousefimashouf, RasoulKeyvani, HosseinKarampoor, SajadLICENSElicense.txtlicense.txttext/plain; charset=utf-82938https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/13211/2/license.txtabceeb1c943c50d3343516f9dbfc110fMD52open accessORIGINALOverview-of-the-current-promising-approaches-for-the-devel_2020_Internationa.pdfOverview-of-the-current-promising-approaches-for-the-devel_2020_Internationa.pdfDocumento reservadoapplication/pdf7898014https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/13211/3/Overview-of-the-current-promising-approaches-for-the-devel_2020_Internationa.pdfd463b4f29a55eb3e04368c5a94e8e3baMD53embargoed access|||2220-09-01THUMBNAILCaptura.JPGCaptura.JPGimage/jpeg68168https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/13211/4/Captura.JPG64626985c3200aeea1ad6a373717ac97MD54open accessOverview-of-the-current-promising-approaches-for-the-devel_2020_Internationa.pdf.jpgOverview-of-the-current-promising-approaches-for-the-devel_2020_Internationa.pdf.jpgIM Thumbnailimage/jpeg15257https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/13211/5/Overview-of-the-current-promising-approaches-for-the-devel_2020_Internationa.pdf.jpg920518a9ec1696cd21370a755b534b2dMD55open access20.500.12010/13211oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/132112020-09-12 10:14:01.143embargoed access|||2220-09-01Repositorio Institucional - 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