Dendritic Cell Control of Immune Responses

Dendritic cells (DC) are among the first cells to encounter pathogens and damage in peripheral tissues and, upon activation, DC migrate to lymph nodes where they activate and educate T cells to initiate and shape the immune response. DC present pathogen-derived antigen to T cells and drive T cell di...

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Autores:
Tipo de recurso:
Book
Fecha de publicación:
2016
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/14393
Acceso en línea:
https://www.frontiersin.org/research-topics/1458/dendritic-cell-control-of-immune-responses
http://hdl.handle.net/20.500.12010/14393
Palabra clave:
Medicina
Control dendrítico celular
Regulación inmune
Células dendríticas
Cancer cáncer
Rights
License
Abierto (Texto Completo)
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oai_identifier_str oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/14393
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dc.title.spa.fl_str_mv Dendritic Cell Control of Immune Responses
title Dendritic Cell Control of Immune Responses
spellingShingle Dendritic Cell Control of Immune Responses
Medicina
Control dendrítico celular
Regulación inmune
Células dendríticas
Cancer cáncer
title_short Dendritic Cell Control of Immune Responses
title_full Dendritic Cell Control of Immune Responses
title_fullStr Dendritic Cell Control of Immune Responses
title_full_unstemmed Dendritic Cell Control of Immune Responses
title_sort Dendritic Cell Control of Immune Responses
dc.subject.spa.fl_str_mv Medicina
topic Medicina
Control dendrítico celular
Regulación inmune
Células dendríticas
Cancer cáncer
dc.subject.lemb.spa.fl_str_mv Control dendrítico celular
Regulación inmune
dc.subject.lemb.none.fl_str_mv Células dendríticas
dc.subject.keyword.spa.fl_str_mv Cancer cáncer
description Dendritic cells (DC) are among the first cells to encounter pathogens and damage in peripheral tissues and, upon activation, DC migrate to lymph nodes where they activate and educate T cells to initiate and shape the immune response. DC present pathogen-derived antigen to T cells and drive T cell differentiation into particular effector cells through the expression and secretion of co-stimulatory molecules and cytokines respectively. The study of DC biology has included the identification of multiple DC subsets in tissues and lymphoid organs, the differentiation and plasticity of DC subsets, the functional consequences of DC interaction with pathogen, control of DC migratory properties and the impact of DC on T cell activation and differentiation. In recent years sophisticated systems biology approaches have been developed to deepen our understanding of DC function. These studies have identified differences between DC subsets located in various tissues and critical factors that drive the outcome of the interaction between DC and T cells. DC are currently being used in in various clinical therapeutic settings, including as vaccines for cancer and autoimmune disease. A clear understanding of DC factors that contribute to specific immune responses is vital to the success of DC based therapies. This research topic will give a comprehensive overview of current issues in DC biology and provides an update on the clinical uses of DC in the therapy of autoimmunity and cancer.
publishDate 2016
dc.date.created.none.fl_str_mv 2016-01-19
dc.date.accessioned.none.fl_str_mv 2020-10-13T16:56:17Z
dc.date.available.none.fl_str_mv 2020-10-13T16:56:17Z
dc.type.local.spa.fl_str_mv Libro
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2f33
format http://purl.org/coar/resource_type/c_2f33
dc.identifier.isbn.none.fl_str_mv 978-2-889-19868-9
dc.identifier.issn.none.fl_str_mv 1664+8714
dc.identifier.other.none.fl_str_mv https://www.frontiersin.org/research-topics/1458/dendritic-cell-control-of-immune-responses
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12010/14393
dc.identifier.doi.none.fl_str_mv 10.3389/978-2-88919-868-9
identifier_str_mv 978-2-889-19868-9
1664+8714
10.3389/978-2-88919-868-9
url https://www.frontiersin.org/research-topics/1458/dendritic-cell-control-of-immune-responses
http://hdl.handle.net/20.500.12010/14393
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.references.none.fl_str_mv Morel, P. A., Butterfield. L. H., eds. (2016). Dendritic Cell Control of Immune Responses. Lausanne: Frontiers Media. doi: 10.3389/978-2-88919-868-9
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.local.spa.fl_str_mv Abierto (Texto Completo)
dc.rights.creativecommons.none.fl_str_mv https://creativecommons.org/licenses/by/4.0/legalcode
rights_invalid_str_mv Abierto (Texto Completo)
https://creativecommons.org/licenses/by/4.0/legalcode
http://purl.org/coar/access_right/c_abf2
dc.format.extent.spa.fl_str_mv 123 páginas
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Frontiers Media SA
institution Universidad de Bogotá Jorge Tadeo Lozano
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https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14393/2/license.txt
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spelling 2020-10-13T16:56:17Z2020-10-13T16:56:17Z2016-01-19978-2-889-19868-91664+8714https://www.frontiersin.org/research-topics/1458/dendritic-cell-control-of-immune-responseshttp://hdl.handle.net/20.500.12010/1439310.3389/978-2-88919-868-9123 páginasapplication/pdfengFrontiers Media SAMedicinaControl dendrítico celularRegulación inmuneCélulas dendríticasCancer cáncerDendritic Cell Control of Immune ResponsesLibrohttp://purl.org/coar/resource_type/c_2f33Abierto (Texto Completo)https://creativecommons.org/licenses/by/4.0/legalcodehttp://purl.org/coar/access_right/c_abf2Morel, P. A., Butterfield. L. H., eds. (2016). Dendritic Cell Control of Immune Responses. Lausanne: Frontiers Media. doi: 10.3389/978-2-88919-868-9Dendritic cells (DC) are among the first cells to encounter pathogens and damage in peripheral tissues and, upon activation, DC migrate to lymph nodes where they activate and educate T cells to initiate and shape the immune response. DC present pathogen-derived antigen to T cells and drive T cell differentiation into particular effector cells through the expression and secretion of co-stimulatory molecules and cytokines respectively. The study of DC biology has included the identification of multiple DC subsets in tissues and lymphoid organs, the differentiation and plasticity of DC subsets, the functional consequences of DC interaction with pathogen, control of DC migratory properties and the impact of DC on T cell activation and differentiation. In recent years sophisticated systems biology approaches have been developed to deepen our understanding of DC function. These studies have identified differences between DC subsets located in various tissues and critical factors that drive the outcome of the interaction between DC and T cells. DC are currently being used in in various clinical therapeutic settings, including as vaccines for cancer and autoimmune disease. A clear understanding of DC factors that contribute to specific immune responses is vital to the success of DC based therapies. This research topic will give a comprehensive overview of current issues in DC biology and provides an update on the clinical uses of DC in the therapy of autoimmunity and cancer.Morel, Penelope AnneButterfield, Lisa HeleneORIGINALDendritic Cell Control of Immune Responses_59.PDFDendritic Cell Control of Immune Responses_59.PDFVer documentoapplication/pdf16921501https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14393/1/Dendritic%20Cell%20Control%20of%20Immune%20Responses_59.PDF836ce4efc98fbe49fb2c6898f086350aMD51open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-82938https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14393/2/license.txtabceeb1c943c50d3343516f9dbfc110fMD52open accessTHUMBNAILDendritic Cell Control of Immune Responses_59.PDF.jpgDendritic Cell Control of Immune Responses_59.PDF.jpgIM Thumbnailimage/jpeg20931https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14393/3/Dendritic%20Cell%20Control%20of%20Immune%20Responses_59.PDF.jpgbccd17e875b8d47f7b80c630f68f0646MD53open access20.500.12010/14393oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/143932021-01-21 18:26:32.67open accessRepositorio Institucional - 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