COVID-19: Clinical aspects and therapeutics responses

COVID-19 has created havoc in the world by causing thousands of demises in a short period of time. Up till now, several attempts have been made for potential therapeutics against SARS-COV2. In this retrospective, single-center study, we extracted data from 122 COVID-19, RT-PCR confirmed patients. wh...

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Autores:
Tipo de recurso:
Article of investigation
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/13904
Acceso en línea:
https://doi.org/10.1016/j.jsps.2020.06.022
http://hdl.handle.net/20.500.12010/13904
Palabra clave:
COVID-19
Therapeutics
Mild symptoms
TCM
Recoveries
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
Rights
License
Abierto (Texto Completo)
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dc.title.spa.fl_str_mv COVID-19: Clinical aspects and therapeutics responses
title COVID-19: Clinical aspects and therapeutics responses
spellingShingle COVID-19: Clinical aspects and therapeutics responses
COVID-19
Therapeutics
Mild symptoms
TCM
Recoveries
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
title_short COVID-19: Clinical aspects and therapeutics responses
title_full COVID-19: Clinical aspects and therapeutics responses
title_fullStr COVID-19: Clinical aspects and therapeutics responses
title_full_unstemmed COVID-19: Clinical aspects and therapeutics responses
title_sort COVID-19: Clinical aspects and therapeutics responses
dc.subject.spa.fl_str_mv COVID-19
Therapeutics
Mild symptoms
TCM
Recoveries
topic COVID-19
Therapeutics
Mild symptoms
TCM
Recoveries
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
dc.subject.lemb.spa.fl_str_mv Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
description COVID-19 has created havoc in the world by causing thousands of demises in a short period of time. Up till now, several attempts have been made for potential therapeutics against SARS-COV2. In this retrospective, single-center study, we extracted data from 122 COVID-19, RT-PCR confirmed patients. who were treated with a new treatment strategy of lianhuaqingwen with Arbidol Hydrochloride. The patients were either asymptomatic or had mild symptoms for COVID-19 disease. Of 122 patients 21 (17.21%) patients developed severe conditions of COVID-19, while total 111 (90.9%) experienced mild symptoms such as fever in 93 (76.22%) patients, cough in 23 (20.17%) and muscle pain were observed in total 8 (7%) patients. Furthermore our newly applied drugs combination (Lianhuaqingwen and Arbidol Hydrochloride) showed therapeutic effects in 5–7 days in patients with mild symptoms with 98% recovery rate. These results indicate that COVID-19 patients with mild symptoms can be treated with Lianhuaqingwen and Arbidol Hydrochloride. However, extensive clinical investigations are required to confirm the effectiveness of these drugs.
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-09-28T16:20:18Z
dc.date.available.none.fl_str_mv 2020-09-28T16:20:18Z
dc.date.created.none.fl_str_mv 2020
dc.type.local.spa.fl_str_mv Artículo
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
format http://purl.org/coar/resource_type/c_2df8fbb1
dc.identifier.issn.spa.fl_str_mv 1319-0164
dc.identifier.other.spa.fl_str_mv https://doi.org/10.1016/j.jsps.2020.06.022
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12010/13904
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1016/j.jsps.2020.06.022
identifier_str_mv 1319-0164
url https://doi.org/10.1016/j.jsps.2020.06.022
http://hdl.handle.net/20.500.12010/13904
dc.language.iso.spa.fl_str_mv eng
language eng
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.local.spa.fl_str_mv Abierto (Texto Completo)
rights_invalid_str_mv Abierto (Texto Completo)
http://purl.org/coar/access_right/c_abf2
dc.format.extent.spa.fl_str_mv 5 páginas
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Saudi Pharmaceutical Journal
dc.source.spa.fl_str_mv reponame:Expeditio Repositorio Institucional UJTL
instname:Universidad de Bogotá Jorge Tadeo Lozano
instname_str Universidad de Bogotá Jorge Tadeo Lozano
institution Universidad de Bogotá Jorge Tadeo Lozano
reponame_str Expeditio Repositorio Institucional UJTL
collection Expeditio Repositorio Institucional UJTL
bitstream.url.fl_str_mv https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/13904/2/license.txt
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spelling 2020-09-28T16:20:18Z2020-09-28T16:20:18Z20201319-0164https://doi.org/10.1016/j.jsps.2020.06.022http://hdl.handle.net/20.500.12010/13904https://doi.org/10.1016/j.jsps.2020.06.022COVID-19 has created havoc in the world by causing thousands of demises in a short period of time. Up till now, several attempts have been made for potential therapeutics against SARS-COV2. In this retrospective, single-center study, we extracted data from 122 COVID-19, RT-PCR confirmed patients. who were treated with a new treatment strategy of lianhuaqingwen with Arbidol Hydrochloride. The patients were either asymptomatic or had mild symptoms for COVID-19 disease. Of 122 patients 21 (17.21%) patients developed severe conditions of COVID-19, while total 111 (90.9%) experienced mild symptoms such as fever in 93 (76.22%) patients, cough in 23 (20.17%) and muscle pain were observed in total 8 (7%) patients. Furthermore our newly applied drugs combination (Lianhuaqingwen and Arbidol Hydrochloride) showed therapeutic effects in 5–7 days in patients with mild symptoms with 98% recovery rate. These results indicate that COVID-19 patients with mild symptoms can be treated with Lianhuaqingwen and Arbidol Hydrochloride. However, extensive clinical investigations are required to confirm the effectiveness of these drugs.5 páginasapplication/pdfengSaudi Pharmaceutical Journalreponame:Expeditio Repositorio Institucional UJTLinstname:Universidad de Bogotá Jorge Tadeo LozanoCOVID-19TherapeuticsMild symptomsTCMRecoveriesSíndrome respiratorio agudo graveCOVID-19SARS-CoV-2CoronavirusCOVID-19: Clinical aspects and therapeutics responsesArtículohttp://purl.org/coar/resource_type/c_2df8fbb1Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2Khan, SulimanAli, AshaqShi, HongweiSiddique, RabeeaShabanaNabi, GhulamHu, JunjieWang, TiejunDong, MenZaman, WajidHan, GuangLICENSElicense.txtlicense.txttext/plain; charset=utf-82938https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/13904/2/license.txtabceeb1c943c50d3343516f9dbfc110fMD52open accessTHUMBNAILCOVID-19--Clinical-aspects-and-therapeutics-re_2020_Saudi-Pharmaceutical-Jou.pdf.jpgCOVID-19--Clinical-aspects-and-therapeutics-re_2020_Saudi-Pharmaceutical-Jou.pdf.jpgIM Thumbnailimage/jpeg22206https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/13904/3/COVID-19--Clinical-aspects-and-therapeutics-re_2020_Saudi-Pharmaceutical-Jou.pdf.jpg680dc7b9b8a0295ca70698a1d42b266cMD53open access20.500.12010/13904oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/139042021-03-17 20:14:51.877metadata only accessRepositorio Institucional - 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