Recent trends in protein and peptide-based biomaterials for advanced drug delivery
Abstract: Engineering protein and peptide-based materials for drug delivery applications has gained momentum due to their favorable biochemical and biophysical properties over synthetic materials, including biocompatibility, ease of synthesis and purification, tunability, scalability, and lack of to...
- Autores:
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2020
- Institución:
- Universidad de Bogotá Jorge Tadeo Lozano
- Repositorio:
- Expeditio: repositorio UTadeo
- Idioma:
- eng
- OAI Identifier:
- oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12738
- Acceso en línea:
- https://doi.org/10.1016/j.addr.2020.08.008
http://hdl.handle.net/20.500.12010/12738
- Palabra clave:
- Drug delivery
Polypeptides
Recombinant proteins
Bioinspired materials
Hierarchical self-assembly
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
- Rights
- License
- Acceso restringido
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| dc.title.spa.fl_str_mv |
Recent trends in protein and peptide-based biomaterials for advanced drug delivery |
| title |
Recent trends in protein and peptide-based biomaterials for advanced drug delivery |
| spellingShingle |
Recent trends in protein and peptide-based biomaterials for advanced drug delivery Drug delivery Polypeptides Recombinant proteins Bioinspired materials Hierarchical self-assembly Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
| title_short |
Recent trends in protein and peptide-based biomaterials for advanced drug delivery |
| title_full |
Recent trends in protein and peptide-based biomaterials for advanced drug delivery |
| title_fullStr |
Recent trends in protein and peptide-based biomaterials for advanced drug delivery |
| title_full_unstemmed |
Recent trends in protein and peptide-based biomaterials for advanced drug delivery |
| title_sort |
Recent trends in protein and peptide-based biomaterials for advanced drug delivery |
| dc.subject.spa.fl_str_mv |
Drug delivery Polypeptides Recombinant proteins Bioinspired materials Hierarchical self-assembly |
| topic |
Drug delivery Polypeptides Recombinant proteins Bioinspired materials Hierarchical self-assembly Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
| dc.subject.lemb.spa.fl_str_mv |
Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
| description |
Abstract: Engineering protein and peptide-based materials for drug delivery applications has gained momentum due to their favorable biochemical and biophysical properties over synthetic materials, including biocompatibility, ease of synthesis and purification, tunability, scalability, and lack of toxicity. These biomolecules have been used to develop a host of drug delivery platforms, such as peptide- and protein-drug conjugates, injectable particles, and drug depots to deliver small molecule drugs, therapeutic proteins, and nucleic acids. In this review, we discuss progress in engineering the architecture and biological functions of peptide-based biomaterials —naturally derived, chemically synthesized and recombinant— with a focus on the molecular features that modulate their structure-function relationships for drug delivery |
| publishDate |
2020 |
| dc.date.accessioned.none.fl_str_mv |
2020-09-04T20:22:15Z |
| dc.date.available.none.fl_str_mv |
2020-09-04T20:22:15Z |
| dc.date.created.none.fl_str_mv |
2020 |
| dc.type.local.spa.fl_str_mv |
Artículo |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.identifier.issn.spa.fl_str_mv |
0169-409X |
| dc.identifier.other.spa.fl_str_mv |
https://doi.org/10.1016/j.addr.2020.08.008 |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/20.500.12010/12738 |
| dc.identifier.doi.spa.fl_str_mv |
https://doi.org/10.1016/j.addr.2020.08.008 |
| identifier_str_mv |
0169-409X |
| url |
https://doi.org/10.1016/j.addr.2020.08.008 http://hdl.handle.net/20.500.12010/12738 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
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http://purl.org/coar/access_right/c_f1cf |
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Acceso restringido |
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Acceso restringido http://purl.org/coar/access_right/c_f1cf |
| dc.format.extent.spa.fl_str_mv |
168 páginas |
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image/jepg |
| dc.publisher.spa.fl_str_mv |
Advanced Drug Delivery Reviews |
| dc.source.spa.fl_str_mv |
reponame:Expeditio Repositorio Institucional UJTL instname:Universidad de Bogotá Jorge Tadeo Lozano |
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Universidad de Bogotá Jorge Tadeo Lozano |
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Universidad de Bogotá Jorge Tadeo Lozano |
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Expeditio Repositorio Institucional UJTL |
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Expeditio Repositorio Institucional UJTL |
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2020-09-04T20:22:15Z2020-09-04T20:22:15Z20200169-409Xhttps://doi.org/10.1016/j.addr.2020.08.008http://hdl.handle.net/20.500.12010/12738https://doi.org/10.1016/j.addr.2020.08.008Abstract: Engineering protein and peptide-based materials for drug delivery applications has gained momentum due to their favorable biochemical and biophysical properties over synthetic materials, including biocompatibility, ease of synthesis and purification, tunability, scalability, and lack of toxicity. These biomolecules have been used to develop a host of drug delivery platforms, such as peptide- and protein-drug conjugates, injectable particles, and drug depots to deliver small molecule drugs, therapeutic proteins, and nucleic acids. In this review, we discuss progress in engineering the architecture and biological functions of peptide-based biomaterials —naturally derived, chemically synthesized and recombinant— with a focus on the molecular features that modulate their structure-function relationships for drug delivery168 páginasimage/jepgengAdvanced Drug Delivery Reviewsreponame:Expeditio Repositorio Institucional UJTLinstname:Universidad de Bogotá Jorge Tadeo LozanoDrug deliveryPolypeptidesRecombinant proteinsBioinspired materialsHierarchical self-assemblySíndrome respiratorio agudo graveCOVID-19SARS-CoV-2CoronavirusRecent trends in protein and peptide-based biomaterials for advanced drug deliveryArtículohttp://purl.org/coar/resource_type/c_2df8fbb1Acceso restringidohttp://purl.org/coar/access_right/c_f1cfVaranko, AnastasiaSaha, SoumenChilkoti, AshutoshORIGINALCaptura.PNGCaptura.PNGVer portadaimage/png83994https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12738/1/Captura.PNG72c6b08e8126f522f10cab008435e766MD51open accessRecent-trends-in-protein-and-peptide-based-biomateri_2020_Advanced-Drug-Deli.pdfRecent-trends-in-protein-and-peptide-based-biomateri_2020_Advanced-Drug-Deli.pdfArtículo reservadoapplication/pdf25226875https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12738/3/Recent-trends-in-protein-and-peptide-based-biomateri_2020_Advanced-Drug-Deli.pdf8767823d7197d28250610db08eb1a53cMD53embargoed access|||2200-09-04LICENSElicense.txtlicense.txttext/plain; charset=utf-82938https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12738/2/license.txtabceeb1c943c50d3343516f9dbfc110fMD52open accessTHUMBNAILCaptura.PNGCaptura.PNGPortadaimage/png83994https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12738/4/Captura.PNG72c6b08e8126f522f10cab008435e766MD54open accessRecent-trends-in-protein-and-peptide-based-biomateri_2020_Advanced-Drug-Deli.pdf.jpgRecent-trends-in-protein-and-peptide-based-biomateri_2020_Advanced-Drug-Deli.pdf.jpgIM Thumbnailimage/jpeg10212https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12738/5/Recent-trends-in-protein-and-peptide-based-biomateri_2020_Advanced-Drug-Deli.pdf.jpg7c84949a7e734a1a16dcaaf258bd4c0cMD55open access20.500.12010/12738oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/127382020-09-04 15:22:15.367open accessRepositorio Institucional - Universidad Jorge Tadeo Lozanoexpeditio@utadeo.edu.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 |