Nanotheranostics against COVID-19: From multivalent to immune-targeted materials
Destructive impacts of COVID-19 pandemic worldwide necessitates taking more appropriate measures for mitigating virus spread and development of the effective theranostic agents. In general, high heterogeneity of viruses is a major challenging issue towards the development of effective antiviral agen...
- Autores:
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2020
- Institución:
- Universidad de Bogotá Jorge Tadeo Lozano
- Repositorio:
- Expeditio: repositorio UTadeo
- Idioma:
- eng
- OAI Identifier:
- oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12751
- Acceso en línea:
- https://doi.org/10.1016/j.jconrel.2020.08.060
http://hdl.handle.net/20.500.12010/12751
- Palabra clave:
- COVID-19
Coronavirus
Nanotechnology
Nanoparticle
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
- Rights
- License
- Acceso restringido
id |
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oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12751 |
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repository_id_str |
|
dc.title.spa.fl_str_mv |
Nanotheranostics against COVID-19: From multivalent to immune-targeted materials |
title |
Nanotheranostics against COVID-19: From multivalent to immune-targeted materials |
spellingShingle |
Nanotheranostics against COVID-19: From multivalent to immune-targeted materials COVID-19 Coronavirus Nanotechnology Nanoparticle Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
title_short |
Nanotheranostics against COVID-19: From multivalent to immune-targeted materials |
title_full |
Nanotheranostics against COVID-19: From multivalent to immune-targeted materials |
title_fullStr |
Nanotheranostics against COVID-19: From multivalent to immune-targeted materials |
title_full_unstemmed |
Nanotheranostics against COVID-19: From multivalent to immune-targeted materials |
title_sort |
Nanotheranostics against COVID-19: From multivalent to immune-targeted materials |
dc.subject.spa.fl_str_mv |
COVID-19 Coronavirus Nanotechnology Nanoparticle |
topic |
COVID-19 Coronavirus Nanotechnology Nanoparticle Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
dc.subject.lemb.spa.fl_str_mv |
Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
description |
Destructive impacts of COVID-19 pandemic worldwide necessitates taking more appropriate measures for mitigating virus spread and development of the effective theranostic agents. In general, high heterogeneity of viruses is a major challenging issue towards the development of effective antiviral agents. Regarding the coronavirus, its high mutation rates can negatively affect virus detection process or the efficiency of drugs and vaccines in development or induce drug resistance. Bioengineered nanomaterials with suitable physicochemical characteristics for sitespecific therapeutic delivery, highly-sensitive nanobiosensors for detection of very low virus concentration, and real-time protections using the nanorobots can provide roadmaps towards the imminent breakthroughs in theranostics of a variety of diseases including the COVID-19. Besides revolutionizing the classical disinfection procedures, state-of-the-art nanotechnologybased approaches enable providing the analytical tools for accelerated monitoring of coronavirus and associated biomarkers or drug delivery towards the pulmonary system or other affected organs. Multivalent nanomaterials capable of interaction with multivalent pathogens including the viruses could be suitable candidates for viral detection and prevention of further infections. Besides the inactivation or destruction of the virus, functionalized nanoparticles capable of modulating patient’s immune response might be of great significance for attenuating the exaggerated inflammatory reactions or development of the effective nanovaccines and medications against the virus pandemics including the COVID-19. |
publishDate |
2020 |
dc.date.accessioned.none.fl_str_mv |
2020-09-04T21:03:20Z |
dc.date.available.none.fl_str_mv |
2020-09-04T21:03:20Z |
dc.date.created.none.fl_str_mv |
2020 |
dc.type.local.spa.fl_str_mv |
Artículo |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
format |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.identifier.issn.spa.fl_str_mv |
0168-3659 |
dc.identifier.other.spa.fl_str_mv |
https://doi.org/10.1016/j.jconrel.2020.08.060 |
dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/20.500.12010/12751 |
dc.identifier.doi.spa.fl_str_mv |
https://doi.org/10.1016/j.jconrel.2020.08.060 |
identifier_str_mv |
0168-3659 |
url |
https://doi.org/10.1016/j.jconrel.2020.08.060 http://hdl.handle.net/20.500.12010/12751 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_f1cf |
dc.rights.local.spa.fl_str_mv |
Acceso restringido |
rights_invalid_str_mv |
Acceso restringido http://purl.org/coar/access_right/c_f1cf |
dc.format.extent.spa.fl_str_mv |
78 páginas |
dc.format.mimetype.spa.fl_str_mv |
image/jepg |
dc.publisher.spa.fl_str_mv |
Journal of Controlled Release |
dc.source.spa.fl_str_mv |
reponame:Expeditio Repositorio Institucional UJTL instname:Universidad de Bogotá Jorge Tadeo Lozano |
instname_str |
Universidad de Bogotá Jorge Tadeo Lozano |
institution |
Universidad de Bogotá Jorge Tadeo Lozano |
reponame_str |
Expeditio Repositorio Institucional UJTL |
collection |
Expeditio Repositorio Institucional UJTL |
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2020-09-04T21:03:20Z2020-09-04T21:03:20Z20200168-3659https://doi.org/10.1016/j.jconrel.2020.08.060http://hdl.handle.net/20.500.12010/12751https://doi.org/10.1016/j.jconrel.2020.08.060Destructive impacts of COVID-19 pandemic worldwide necessitates taking more appropriate measures for mitigating virus spread and development of the effective theranostic agents. In general, high heterogeneity of viruses is a major challenging issue towards the development of effective antiviral agents. Regarding the coronavirus, its high mutation rates can negatively affect virus detection process or the efficiency of drugs and vaccines in development or induce drug resistance. Bioengineered nanomaterials with suitable physicochemical characteristics for sitespecific therapeutic delivery, highly-sensitive nanobiosensors for detection of very low virus concentration, and real-time protections using the nanorobots can provide roadmaps towards the imminent breakthroughs in theranostics of a variety of diseases including the COVID-19. Besides revolutionizing the classical disinfection procedures, state-of-the-art nanotechnologybased approaches enable providing the analytical tools for accelerated monitoring of coronavirus and associated biomarkers or drug delivery towards the pulmonary system or other affected organs. Multivalent nanomaterials capable of interaction with multivalent pathogens including the viruses could be suitable candidates for viral detection and prevention of further infections. Besides the inactivation or destruction of the virus, functionalized nanoparticles capable of modulating patient’s immune response might be of great significance for attenuating the exaggerated inflammatory reactions or development of the effective nanovaccines and medications against the virus pandemics including the COVID-19.78 páginasimage/jepgengJournal of Controlled Releasereponame:Expeditio Repositorio Institucional UJTLinstname:Universidad de Bogotá Jorge Tadeo LozanoCOVID-19CoronavirusNanotechnologyNanoparticleSíndrome respiratorio agudo graveCOVID-19SARS-CoV-2CoronavirusNanotheranostics against COVID-19: From multivalent to immune-targeted materialsArtículohttp://purl.org/coar/resource_type/c_2df8fbb1Acceso restringidohttp://purl.org/coar/access_right/c_f1cfHassanzadeh, ParichehrORIGINALCaptura.PNGCaptura.PNGVer portadaimage/png57838https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12751/1/Captura.PNGb8a0928cef2ab896bbee06df0e86b017MD51open accessNanotheranostics-against-COVID-19--From-multivalent-_2020_Journal-of-Control.pdfNanotheranostics-against-COVID-19--From-multivalent-_2020_Journal-of-Control.pdfArtículo reservadoapplication/pdf7027563https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12751/3/Nanotheranostics-against-COVID-19--From-multivalent-_2020_Journal-of-Control.pdf0fbb4c2a26d8be416d35ab35fb0bdad0MD53embargoed access|||2200-09-04LICENSElicense.txtlicense.txttext/plain; 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