Promising role for mesenchymal stromal cells in coronavirus infectious disease-19 (COVID-19)-related severe acute respiratory syndrome?

Mesenchymal stromal cells (MSC) have immune regulatory and tissue regenerative properties. MSCs are being studied as a therapy option for many inflammatory and immune disorders and are approved to treat acute graft-versus-host disease (GvHD). The severe acute respiratory syndrome coronavirus-2 (SARS...

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Autores:
Tipo de recurso:
Article of investigation
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12485
Acceso en línea:
https://doi.org/10.1016/j.blre.2020.100742
http://hdl.handle.net/20.500.12010/12485
Palabra clave:
Mesenchymal stromal cell
SARS-CoV2
COVID-19
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
Rights
License
Acceso restringido
id UTADEO2_a9e68f4a922a60ed4339b5d351cf2f17
oai_identifier_str oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12485
network_acronym_str UTADEO2
network_name_str Expeditio: repositorio UTadeo
repository_id_str
dc.title.spa.fl_str_mv Promising role for mesenchymal stromal cells in coronavirus infectious disease-19 (COVID-19)-related severe acute respiratory syndrome?
title Promising role for mesenchymal stromal cells in coronavirus infectious disease-19 (COVID-19)-related severe acute respiratory syndrome?
spellingShingle Promising role for mesenchymal stromal cells in coronavirus infectious disease-19 (COVID-19)-related severe acute respiratory syndrome?
Mesenchymal stromal cell
SARS-CoV2
COVID-19
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
title_short Promising role for mesenchymal stromal cells in coronavirus infectious disease-19 (COVID-19)-related severe acute respiratory syndrome?
title_full Promising role for mesenchymal stromal cells in coronavirus infectious disease-19 (COVID-19)-related severe acute respiratory syndrome?
title_fullStr Promising role for mesenchymal stromal cells in coronavirus infectious disease-19 (COVID-19)-related severe acute respiratory syndrome?
title_full_unstemmed Promising role for mesenchymal stromal cells in coronavirus infectious disease-19 (COVID-19)-related severe acute respiratory syndrome?
title_sort Promising role for mesenchymal stromal cells in coronavirus infectious disease-19 (COVID-19)-related severe acute respiratory syndrome?
dc.subject.spa.fl_str_mv Mesenchymal stromal cell
SARS-CoV2
COVID-19
topic Mesenchymal stromal cell
SARS-CoV2
COVID-19
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
dc.subject.lemb.spa.fl_str_mv Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
description Mesenchymal stromal cells (MSC) have immune regulatory and tissue regenerative properties. MSCs are being studied as a therapy option for many inflammatory and immune disorders and are approved to treat acute graft-versus-host disease (GvHD). The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic and associated coronavirus infectious disease-19 (COVID-19) has claimed many lives. Innovative therapies are needed. Preliminary data using MSCs in the setting of acute respiratory distress syndrome (ARDS) in COVID-19 are emerging. We review mechanisms of action of MSCs in inflammatory and immune conditions and discuss a potential role in persons with COVID-19.
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-08-31T19:00:54Z
dc.date.available.none.fl_str_mv 2020-08-31T19:00:54Z
dc.date.created.none.fl_str_mv 2020
dc.type.local.spa.fl_str_mv Artículo
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
format http://purl.org/coar/resource_type/c_2df8fbb1
dc.identifier.issn.spa.fl_str_mv 0268-960X
dc.identifier.other.spa.fl_str_mv https://doi.org/10.1016/j.blre.2020.100742
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12010/12485
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1016/j.blre.2020.100742
identifier_str_mv 0268-960X
url https://doi.org/10.1016/j.blre.2020.100742
http://hdl.handle.net/20.500.12010/12485
dc.language.iso.spa.fl_str_mv eng
language eng
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dc.rights.local.spa.fl_str_mv Acceso restringido
rights_invalid_str_mv Acceso restringido
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dc.format.extent.spa.fl_str_mv 28 páginas
dc.format.mimetype.spa.fl_str_mv image/jepg
dc.publisher.spa.fl_str_mv Blood Reviews
dc.source.spa.fl_str_mv reponame:Expeditio Repositorio Institucional UJTL
instname:Universidad de Bogotá Jorge Tadeo Lozano
instname_str Universidad de Bogotá Jorge Tadeo Lozano
institution Universidad de Bogotá Jorge Tadeo Lozano
reponame_str Expeditio Repositorio Institucional UJTL
collection Expeditio Repositorio Institucional UJTL
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spelling 2020-08-31T19:00:54Z2020-08-31T19:00:54Z20200268-960Xhttps://doi.org/10.1016/j.blre.2020.100742http://hdl.handle.net/20.500.12010/12485https://doi.org/10.1016/j.blre.2020.100742Mesenchymal stromal cells (MSC) have immune regulatory and tissue regenerative properties. MSCs are being studied as a therapy option for many inflammatory and immune disorders and are approved to treat acute graft-versus-host disease (GvHD). The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic and associated coronavirus infectious disease-19 (COVID-19) has claimed many lives. Innovative therapies are needed. Preliminary data using MSCs in the setting of acute respiratory distress syndrome (ARDS) in COVID-19 are emerging. We review mechanisms of action of MSCs in inflammatory and immune conditions and discuss a potential role in persons with COVID-19.28 páginasimage/jepgengBlood Reviewsreponame:Expeditio Repositorio Institucional UJTLinstname:Universidad de Bogotá Jorge Tadeo LozanoMesenchymal stromal cellSARS-CoV2COVID-19Síndrome respiratorio agudo graveCOVID-19SARS-CoV-2CoronavirusPromising role for mesenchymal stromal cells in coronavirus infectious disease-19 (COVID-19)-related severe acute respiratory syndrome?Artículohttp://purl.org/coar/resource_type/c_2df8fbb1Acceso restringidohttp://purl.org/coar/access_right/c_f1cfHamdan, HamdanHashmi, Shahrukh K.Lazarus, HillardGale, Robert PeterQu, WenchunEl Fakih, RiadORIGINALCaptura.PNGCaptura.PNGVer portadaimage/png105285https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12485/1/Captura.PNG789a8bd8d9cd361f6a20d03c2da29fc8MD51open accessPromising-role-for-mesenchymal-stromal-cells-in-coronavirus-infe_2020_Blood-.pdfPromising-role-for-mesenchymal-stromal-cells-in-coronavirus-infe_2020_Blood-.pdfArtículo reservadoapplication/pdf1118938https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12485/3/Promising-role-for-mesenchymal-stromal-cells-in-coronavirus-infe_2020_Blood-.pdfe954feb1748b4623b6ad88c4a218c738MD53embargoed access|||2200-08-31LICENSElicense.txtlicense.txttext/plain; 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