COVID-19 infection and high intracoronary thrombus burden

Coronavirus 2019 (COVID-19) is an acute respiratory disease that has rapidly spread around the world and been declared a global pandemic by the World Health Organization. Emerging evidence demonstrates a strong association with a prothrombotic state and we present the first patient admitted with COV...

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Autores:
Tipo de recurso:
Article of investigation
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12547
Acceso en línea:
https://doi.org/10.1016/j.carrev.2020.07.032
http://hdl.handle.net/20.500.12010/12547
Palabra clave:
COVID-19
Myocardial infartion
Coronary thrombus
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
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License
Acceso restringido
Description
Summary:Coronavirus 2019 (COVID-19) is an acute respiratory disease that has rapidly spread around the world and been declared a global pandemic by the World Health Organization. Emerging evidence demonstrates a strong association with a prothrombotic state and we present the first patient admitted with COVID-19 and an inferior ST-segment elevation myocardial infarction (STEMI) with evidence of high intracoronary thrombus burden. We review the mechanism of the high thrombus burden, which may be driven by the significant cytokine storm, endothelial dysfunction, increase risk of coronary plaque rupture and hypercoagulability.