How to reduce epidemic peaks keeping under control the time-span of the epidemic

One of the main challenges of the measures against the COVID-19 epidemic is to reduce the amplitude of the epidemic peak without increasing without control its timescale. We investigate this problem using the SIR model for the epidemic dynamics, for which reduction of the epidemic peak IP can be ach...

Full description

Autores:
Tipo de recurso:
Article of journal
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12089
Acceso en línea:
https://doi.org/10.1016/j.chaos.2020.109940
http://hdl.handle.net/20.500.12010/12089
Palabra clave:
Epidemic
COVID-19
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
Rights
License
Acceso restringido
id UTADEO2_7ec81e26c66d82c2c53645601e50bf7d
oai_identifier_str oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12089
network_acronym_str UTADEO2
network_name_str Expeditio: repositorio UTadeo
repository_id_str
dc.title.spa.fl_str_mv How to reduce epidemic peaks keeping under control the time-span of the epidemic
title How to reduce epidemic peaks keeping under control the time-span of the epidemic
spellingShingle How to reduce epidemic peaks keeping under control the time-span of the epidemic
Epidemic
COVID-19
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
title_short How to reduce epidemic peaks keeping under control the time-span of the epidemic
title_full How to reduce epidemic peaks keeping under control the time-span of the epidemic
title_fullStr How to reduce epidemic peaks keeping under control the time-span of the epidemic
title_full_unstemmed How to reduce epidemic peaks keeping under control the time-span of the epidemic
title_sort How to reduce epidemic peaks keeping under control the time-span of the epidemic
dc.subject.spa.fl_str_mv Epidemic
COVID-19
topic Epidemic
COVID-19
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
dc.subject.lemb.spa.fl_str_mv Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
description One of the main challenges of the measures against the COVID-19 epidemic is to reduce the amplitude of the epidemic peak without increasing without control its timescale. We investigate this problem using the SIR model for the epidemic dynamics, for which reduction of the epidemic peak IP can be achieved only at the price of increasing the time tP of its occurrence and its entire time-span tE. By means of a time reparametrization we linearize the equations for the SIR dynamics. This allows us to solve exactly the dynamics in the time domain and to derive the scaling behaviour of the size, the timescale and the speed of the epidemics, by reducing the infection rate α and by increasing the removal rate β by a factor of λ. We show that for a given value of the size (IP, the total, IE and average ˆIP number of infected), its occurrence time tP and entire time-span tE can be reduced by a factor 1/λ if the reduction of I is achieved by increasing the removal rate instead of reducing the infection rate. Thus, epidemic containment measures based on tracing, early detection followed by prompt isolation of infected individuals are more efficient than those based on social distancing. We apply our results to the COVID-19 epidemic in Northern Italy. We show that the peak time tP and the entire time span tE could have been reduced by a factor 0.9 ≤ 1/λ ≤ 0.34 with containment measures focused on increasing β instead of reducing α.
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-08-21T16:21:40Z
dc.date.available.none.fl_str_mv 2020-08-21T16:21:40Z
dc.date.created.none.fl_str_mv 2020
dc.type.local.spa.fl_str_mv Artículo
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_6501
format http://purl.org/coar/resource_type/c_6501
dc.identifier.issn.spa.fl_str_mv 0960-0779
dc.identifier.other.spa.fl_str_mv https://doi.org/10.1016/j.chaos.2020.109940
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12010/12089
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1016/j.chaos.2020.109940
identifier_str_mv 0960-0779
url https://doi.org/10.1016/j.chaos.2020.109940
http://hdl.handle.net/20.500.12010/12089
dc.language.iso.spa.fl_str_mv eng
language eng
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_f1cf
dc.rights.local.spa.fl_str_mv Acceso restringido
rights_invalid_str_mv Acceso restringido
http://purl.org/coar/access_right/c_f1cf
dc.format.extent.spa.fl_str_mv 6 páginas
dc.format.mimetype.spa.fl_str_mv image/jepg
dc.publisher.spa.fl_str_mv Chaos, Solitons and Fractals
dc.source.spa.fl_str_mv reponame:Expeditio Repositorio Institucional UJTL
instname:Universidad de Bogotá Jorge Tadeo Lozano
instname_str Universidad de Bogotá Jorge Tadeo Lozano
institution Universidad de Bogotá Jorge Tadeo Lozano
reponame_str Expeditio Repositorio Institucional UJTL
collection Expeditio Repositorio Institucional UJTL
bitstream.url.fl_str_mv https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12089/4/Captura.PNG
https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12089/5/How-to-reduce-epidemic-peaks-keeping-under-control-th_2020_Chaos--Solitons--.pdf.jpg
https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12089/1/Captura.PNG
https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12089/3/How-to-reduce-epidemic-peaks-keeping-under-control-th_2020_Chaos--Solitons--.pdf
https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12089/2/license.txt
bitstream.checksum.fl_str_mv 62b7feb4e023d667da5aa0b4e60d6b90
7021b2afa12f9c264725b0c6cec13924
62b7feb4e023d667da5aa0b4e60d6b90
e768be235870f1ed785107033325957a
abceeb1c943c50d3343516f9dbfc110f
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositorio Institucional - Universidad Jorge Tadeo Lozano
repository.mail.fl_str_mv expeditio@utadeo.edu.co
_version_ 1814213952144408576
spelling 2020-08-21T16:21:40Z2020-08-21T16:21:40Z20200960-0779https://doi.org/10.1016/j.chaos.2020.109940http://hdl.handle.net/20.500.12010/12089https://doi.org/10.1016/j.chaos.2020.109940One of the main challenges of the measures against the COVID-19 epidemic is to reduce the amplitude of the epidemic peak without increasing without control its timescale. We investigate this problem using the SIR model for the epidemic dynamics, for which reduction of the epidemic peak IP can be achieved only at the price of increasing the time tP of its occurrence and its entire time-span tE. By means of a time reparametrization we linearize the equations for the SIR dynamics. This allows us to solve exactly the dynamics in the time domain and to derive the scaling behaviour of the size, the timescale and the speed of the epidemics, by reducing the infection rate α and by increasing the removal rate β by a factor of λ. We show that for a given value of the size (IP, the total, IE and average ˆIP number of infected), its occurrence time tP and entire time-span tE can be reduced by a factor 1/λ if the reduction of I is achieved by increasing the removal rate instead of reducing the infection rate. Thus, epidemic containment measures based on tracing, early detection followed by prompt isolation of infected individuals are more efficient than those based on social distancing. We apply our results to the COVID-19 epidemic in Northern Italy. We show that the peak time tP and the entire time span tE could have been reduced by a factor 0.9 ≤ 1/λ ≤ 0.34 with containment measures focused on increasing β instead of reducing α.6 páginasimage/jepgengChaos, Solitons and Fractalsreponame:Expeditio Repositorio Institucional UJTLinstname:Universidad de Bogotá Jorge Tadeo LozanoEpidemicCOVID-19Síndrome respiratorio agudo graveCOVID-19SARS-CoV-2CoronavirusHow to reduce epidemic peaks keeping under control the time-span of the epidemicArtículohttp://purl.org/coar/resource_type/c_6501Acceso restringidohttp://purl.org/coar/access_right/c_f1cfCadoni, MarianoTHUMBNAILCaptura.PNGCaptura.PNGPortadaimage/png131387https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12089/4/Captura.PNG62b7feb4e023d667da5aa0b4e60d6b90MD54open accessHow-to-reduce-epidemic-peaks-keeping-under-control-th_2020_Chaos--Solitons--.pdf.jpgHow-to-reduce-epidemic-peaks-keeping-under-control-th_2020_Chaos--Solitons--.pdf.jpgIM Thumbnailimage/jpeg15271https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12089/5/How-to-reduce-epidemic-peaks-keeping-under-control-th_2020_Chaos--Solitons--.pdf.jpg7021b2afa12f9c264725b0c6cec13924MD55open accessORIGINALCaptura.PNGCaptura.PNGPortadaimage/png131387https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12089/1/Captura.PNG62b7feb4e023d667da5aa0b4e60d6b90MD51open accessHow-to-reduce-epidemic-peaks-keeping-under-control-th_2020_Chaos--Solitons--.pdfHow-to-reduce-epidemic-peaks-keeping-under-control-th_2020_Chaos--Solitons--.pdfArtículo reservadoapplication/pdf394669https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12089/3/How-to-reduce-epidemic-peaks-keeping-under-control-th_2020_Chaos--Solitons--.pdfe768be235870f1ed785107033325957aMD53embargoed access|||2200-08-21LICENSElicense.txtlicense.txttext/plain; charset=utf-82938https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12089/2/license.txtabceeb1c943c50d3343516f9dbfc110fMD52open access20.500.12010/12089oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/120892020-08-21 11:21:40.483open accessRepositorio Institucional - Universidad Jorge Tadeo Lozanoexpeditio@utadeo.edu.coQXV0b3Jpem8gYWwgU2lzdGVtYSBkZSBCaWJsaW90ZWNhcyBVbml2ZXJzaWRhZCBkZSBCb2dvdMOhIEpvcmdlIFRhZGVvIExvemFubyBwYXJhIHF1ZSBjb24gZmluZXMgYWNhZMOpbWljb3MsIHByZXNlcnZlLCBjb25zZXJ2ZSwgb3JnYW5pY2UsIGVkaXRlIHkgbW9kaWZpcXVlIHRlY25vbMOzZ2ljYW1lbnRlIGVsIGRvY3VtZW50byBhbnRlcmlvcm1lbnRlIGNhcmdhZG8gYWwgUmVwb3NpdG9yaW8gSW5zdGl0dWNpb25hbCBFeHBlZGl0aW8KCkV4Y2VwdHVhbmRvIHF1ZSBlbCBkb2N1bWVudG8gc2VhIGNvbmZpZGVuY2lhbCwgYXV0b3Jpem8gYSB1c3VhcmlvcyBpbnRlcm5vcyB5IGV4dGVybm9zIGRlIGxhIEluc3RpdHVjacOzbiBhIGNvbnN1bHRhciB5IHJlcHJvZHVjaXIgZWwgY29udGVuaWRvIGRlbCBkb2N1bWVudG8gcGFyYSBmaW5lcyBhY2Fkw6ltaWNvcyBudW5jYSBwYXJhIHVzb3MgY29tZXJjaWFsZXMsIGN1YW5kbyBtZWRpYW50ZSBsYSBjb3JyZXNwb25kaWVudGUgY2l0YSBiaWJsaW9ncsOhZmljYSBzZSBsZSBkZSBjcsOpZGl0byBhIGxhIG9icmEgeSBzdShzKSBhdXRvcihzKS4KCkV4Y2VwdHVhbmRvIHF1ZSBlbCBkb2N1bWVudG8gc2VhIGNvbmZpZGVuY2lhbCwgYXV0b3Jpem8gYXBsaWNhciBsYSBsaWNlbmNpYSBkZWwgZXN0w6FuZGFyIGludGVybmFjaW9uYWwgQ3JlYXRpdmUgQ29tbW9ucyAoQXR0cmlidXRpb24tTm9uQ29tbWVyY2lhbC1Ob0Rlcml2YXRpdmVzIDQuMCBJbnRlcm5hdGlvbmFsKSBxdWUgaW5kaWNhIHF1ZSBjdWFscXVpZXIgcGVyc29uYSBwdWVkZSB1c2FyIGxhIG9icmEgZGFuZG8gY3LDqWRpdG8gYWwgYXV0b3IsIHNpbiBwb2RlciBjb21lcmNpYXIgY29uIGxhIG9icmEgeSBzaW4gZ2VuZXJhciBvYnJhcyBkZXJpdmFkYXMuCgpFbCAobG9zKSBhdXRvcihlcykgY2VydGlmaWNhKG4pIHF1ZSBlbCBkb2N1bWVudG8gbm8gaW5mcmluZ2UgbmkgYXRlbnRhIGNvbnRyYSBkZXJlY2hvcyBpbmR1c3RyaWFsZXMsIHBhdHJpbW9uaWFsZXMsIGludGVsZWN0dWFsZXMsIG1vcmFsZXMgbyBjdWFscXVpZXIgb3RybyBkZSB0ZXJjZXJvcywgYXPDrSBtaXNtbyBkZWNsYXJhbiBxdWUgbGEgVW5pdmVyc2lkYWQgSm9yZ2UgVGFkZW8gTG96YW5vIHNlIGVuY3VlbnRyYSBsaWJyZSBkZSB0b2RhIHJlc3BvbnNhYmlsaWRhZCBjaXZpbCwgYWRtaW5pc3RyYXRpdmEgeS9vIHBlbmFsIHF1ZSBwdWVkYSBkZXJpdmFyc2UgZGUgbGEgcHVibGljYWNpw7NuIGRlbCB0cmFiYWpvIGRlIGdyYWRvIHkvbyB0ZXNpcyBlbiBjYWxpZGFkIGRlIGFjY2VzbyBhYmllcnRvIHBvciBjdWFscXVpZXIgbWVkaW8uCgpFbiBjdW1wbGltaWVudG8gY29uIGxvIGRpc3B1ZXN0byBlbiBsYSBMZXkgMTU4MSBkZSAyMDEyIHkgZXNwZWNpYWxtZW50ZSBlbiB2aXJ0dWQgZGUgbG8gZGlzcHVlc3RvIGVuIGVsIEFydMOtY3VsbyAxMCBkZWwgRGVjcmV0byAxMzc3IGRlIDIwMTMsIGF1dG9yaXpvIGEgbGEgVW5pdmVyc2lkYWQgSm9yZ2UgVGFkZW8gTG96YW5vIGEgcHJvY2VkZXIgY29uIGVsIHRyYXRhbWllbnRvIGRlIGxvcyBkYXRvcyBwZXJzb25hbGVzIHBhcmEgZmluZXMgYWNhZMOpbWljb3MsIGhpc3TDs3JpY29zLCBlc3RhZMOtc3RpY29zIHkgYWRtaW5pc3RyYXRpdm9zIGRlIGxhIEluc3RpdHVjacOzbi4gRGUgY29uZm9ybWlkYWQgY29uIGxvIGVzdGFibGVjaWRvIGVuIGVsIGFydMOtY3VsbyAzMCBkZSBsYSBMZXkgMjMgZGUgMTk4MiB5IGVsIGFydMOtY3VsbyAxMSBkZSBsYSBEZWNpc2nDs24gQW5kaW5hIDM1MSBkZSAxOTkzLCBhY2xhcmFtb3MgcXVlIOKAnExvcyBkZXJlY2hvcyBtb3JhbGVzIHNvYnJlIGVsIHRyYWJham8gc29uIHByb3BpZWRhZCBkZSBsb3MgYXV0b3Jlc+KAnSwgbG9zIGN1YWxlcyBzb24gaXJyZW51bmNpYWJsZXMsIGltcHJlc2NyaXB0aWJsZXMsIGluZW1iYXJnYWJsZXMgZSBpbmFsaWVuYWJsZXMuCgpDb24gZWwgcmVnaXN0cm8gZW4gbGEgcMOhZ2luYSwgYXV0b3Jpem8gZGUgbWFuZXJhIGV4cHJlc2EgYSBsYSBGVU5EQUNJw5NOIFVOSVZFUlNJREFEIERFIEJPR09Uw4EgSk9SR0UgVEFERU8gTE9aQU5PLCBlbCB0cmF0YW1pZW50byBkZSBtaXMgZGF0b3MgcGVyc29uYWxlcyBwYXJhIHByb2Nlc2FyIG8gY29uc2VydmFyLCBjb24gZmluZXMgZXN0YWTDrXN0aWNvcywgZGUgY29udHJvbCBvIHN1cGVydmlzacOzbiwgYXPDrSBjb21vIHBhcmEgZWwgZW52w61vIGRlIGluZm9ybWFjacOzbiB2w61hIGNvcnJlbyBlbGVjdHLDs25pY28sIGRlbnRybyBkZWwgbWFyY28gZXN0YWJsZWNpZG8gcG9yIGxhIExleSAxNTgxIGRlIDIwMTIgeSBzdXMgZGVjcmV0b3MgY29tcGxlbWVudGFyaW9zIHNvYnJlIFRyYXRhbWllbnRvIGRlIERhdG9zIFBlcnNvbmFsZXMuIEVuIGN1YWxxdWllciBjYXNvLCBlbnRpZW5kbyBxdWUgcG9kcsOpIGhhY2VyIHVzbyBkZWwgZGVyZWNobyBhIGNvbm9jZXIsIGFjdHVhbGl6YXIsIHJlY3RpZmljYXIgbyBzdXByaW1pciBsb3MgZGF0b3MgcGVyc29uYWxlcyBtZWRpYW50ZSBlbCBlbnbDrW8gZGUgdW5hIGNvbXVuaWNhY2nDs24gZXNjcml0YSBhbCBjb3JyZW8gZWxlY3Ryw7NuaWNvIHByb3RlY2Npb25kYXRvc0B1dGFkZW8uZWR1LmNvLgoKTGEgRlVOREFDScOTTiBVTklWRVJTSURBRCBERSBCT0dPVMOBIEpPUkdFIFRBREVPIExPWkFOTyBubyB1dGlsaXphcsOhIGxvcyBkYXRvcyBwZXJzb25hbGVzIHBhcmEgZmluZXMgZGlmZXJlbnRlcyBhIGxvcyBhbnVuY2lhZG9zIHkgZGFyw6EgdW4gdXNvIGFkZWN1YWRvIHkgcmVzcG9uc2FibGUgYSBzdXMgZGF0b3MgcGVyc29uYWxlcyBkZSBhY3VlcmRvIGNvbiBsYSBkaXJlY3RyaXogZGUgUHJvdGVjY2nDs24gZGUgRGF0b3MgUGVyc29uYWxlcyBxdWUgcG9kcsOhIGNvbnN1bHRhciBlbjogaHR0cDovL3d3dy51dGFkZW8uZWR1LmNvL2VzL2xpbmsvZGVzY3VicmUtbGEtdW5pdmVyc2lkYWQvMi9kb2N1bWVudG9zCg==