Immune literacy: reading, writing and editing adaptive immunity
Advances in reading, writing and editing DNA are providing unprecedented insights into the complexity of immunological systems. This combination of systems and synthetic biology methods is enabling the quantitative and precise understanding of molecular recognition in adaptive immunity, thus providi...
- Autores:
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2020
- Institución:
- Universidad de Bogotá Jorge Tadeo Lozano
- Repositorio:
- Expeditio: repositorio UTadeo
- Idioma:
- eng
- OAI Identifier:
- oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12704
- Acceso en línea:
- https://doi.org/10.1016/j.isci.2020.101519
http://hdl.handle.net/20.500.12010/12704
- Palabra clave:
- Immune literacy
Adaptive immunity
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
- Rights
- License
- Abierto (Texto Completo)
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| dc.title.spa.fl_str_mv |
Immune literacy: reading, writing and editing adaptive immunity |
| title |
Immune literacy: reading, writing and editing adaptive immunity |
| spellingShingle |
Immune literacy: reading, writing and editing adaptive immunity Immune literacy Adaptive immunity Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
| title_short |
Immune literacy: reading, writing and editing adaptive immunity |
| title_full |
Immune literacy: reading, writing and editing adaptive immunity |
| title_fullStr |
Immune literacy: reading, writing and editing adaptive immunity |
| title_full_unstemmed |
Immune literacy: reading, writing and editing adaptive immunity |
| title_sort |
Immune literacy: reading, writing and editing adaptive immunity |
| dc.subject.spa.fl_str_mv |
Immune literacy Adaptive immunity |
| topic |
Immune literacy Adaptive immunity Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
| dc.subject.lemb.spa.fl_str_mv |
Síndrome respiratorio agudo grave COVID-19 SARS-CoV-2 Coronavirus |
| description |
Advances in reading, writing and editing DNA are providing unprecedented insights into the complexity of immunological systems. This combination of systems and synthetic biology methods is enabling the quantitative and precise understanding of molecular recognition in adaptive immunity, thus providing a framework for reprogramming immune responses for translational medicine. In this review, we will highlight state-of-the-art methods such as immune repertoire sequencing, immunoinformatics and immunogenomic engineering and their application towards adaptive immunity. We showcase novel and interdisciplinary approaches that have the promise of transforming the design and breadth of molecular and cellular immunotherapies. |
| publishDate |
2020 |
| dc.date.accessioned.none.fl_str_mv |
2020-09-04T16:09:26Z |
| dc.date.available.none.fl_str_mv |
2020-09-04T16:09:26Z |
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2020 |
| dc.type.local.spa.fl_str_mv |
Artículo |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.identifier.issn.spa.fl_str_mv |
2589-0042 |
| dc.identifier.other.spa.fl_str_mv |
https://doi.org/10.1016/j.isci.2020.101519 |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/20.500.12010/12704 |
| dc.identifier.doi.spa.fl_str_mv |
https://doi.org/10.1016/j.isci.2020.101519 |
| identifier_str_mv |
2589-0042 |
| url |
https://doi.org/10.1016/j.isci.2020.101519 http://hdl.handle.net/20.500.12010/12704 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
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Abierto (Texto Completo) |
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Abierto (Texto Completo) http://purl.org/coar/access_right/c_abf2 |
| dc.format.extent.spa.fl_str_mv |
36 páginas |
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application/pdf |
| dc.publisher.spa.fl_str_mv |
ISCIENCE |
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reponame:Expeditio Repositorio Institucional UJTL instname:Universidad de Bogotá Jorge Tadeo Lozano |
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Universidad de Bogotá Jorge Tadeo Lozano |
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Universidad de Bogotá Jorge Tadeo Lozano |
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Expeditio Repositorio Institucional UJTL |
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2020-09-04T16:09:26Z2020-09-04T16:09:26Z20202589-0042https://doi.org/10.1016/j.isci.2020.101519http://hdl.handle.net/20.500.12010/12704https://doi.org/10.1016/j.isci.2020.101519Advances in reading, writing and editing DNA are providing unprecedented insights into the complexity of immunological systems. This combination of systems and synthetic biology methods is enabling the quantitative and precise understanding of molecular recognition in adaptive immunity, thus providing a framework for reprogramming immune responses for translational medicine. In this review, we will highlight state-of-the-art methods such as immune repertoire sequencing, immunoinformatics and immunogenomic engineering and their application towards adaptive immunity. We showcase novel and interdisciplinary approaches that have the promise of transforming the design and breadth of molecular and cellular immunotherapies.36 páginasapplication/pdfengISCIENCEreponame:Expeditio Repositorio Institucional UJTLinstname:Universidad de Bogotá Jorge Tadeo LozanoImmune literacyAdaptive immunitySíndrome respiratorio agudo graveCOVID-19SARS-CoV-2CoronavirusImmune literacy: reading, writing and editing adaptive immunityArtículohttp://purl.org/coar/resource_type/c_2df8fbb1Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2Csepregi, LuciaEhling, RoyWagner, BastianReddy, Sai T.ORIGINAL1-s2.0-S2589004220307112-main.pdf1-s2.0-S2589004220307112-main.pdfVer atículoapplication/pdf5361292https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12704/1/1-s2.0-S2589004220307112-main.pdf8db39937f5614cfc39928882b640b6f3MD51open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-82938https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12704/2/license.txtabceeb1c943c50d3343516f9dbfc110fMD52open accessTHUMBNAIL1-s2.0-S2589004220307112-main.pdf.jpg1-s2.0-S2589004220307112-main.pdf.jpgIM Thumbnailimage/jpeg11065https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12704/3/1-s2.0-S2589004220307112-main.pdf.jpg1b05e32f3415015282fd214532b64852MD53open access20.500.12010/12704oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/127042020-09-04 11:09:26.521open accessRepositorio Institucional - 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