Molecular Function and Regulation of Non-coding RNAs in Multifactorial Diseases
Our understanding of the mechanisms underlying the development of multifactorial diseases such as diabetes, autism, Alzheimer's disease, and cancer has been greatly advanced. Non-coding RNAs (ncRNAs), generally including microRNAs and long non-coding RNAs, have recently been found to have poten...
- Autores:
- Tipo de recurso:
- Book
- Fecha de publicación:
- 2016
- Institución:
- Universidad de Bogotá Jorge Tadeo Lozano
- Repositorio:
- Expeditio: repositorio UTadeo
- Idioma:
- eng
- OAI Identifier:
- oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/14332
- Acceso en línea:
- https://www.frontiersin.org/research-topics/3338/molecular-function-and-regulation-of-non-coding-rnas-in-multifactorial-diseases
http://hdl.handle.net/20.500.12010/14332
- Palabra clave:
- Genetics
Science (General)
Biomarker
Long non -- Coding RNA
Complex disease
Mirna
Cancer
- Rights
- License
- Abierto (Texto Completo)
| id |
UTADEO2_53a42bbe2564bc7ff1db92f8d51724e6 |
|---|---|
| oai_identifier_str |
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/14332 |
| network_acronym_str |
UTADEO2 |
| network_name_str |
Expeditio: repositorio UTadeo |
| repository_id_str |
|
| dc.title.spa.fl_str_mv |
Molecular Function and Regulation of Non-coding RNAs in Multifactorial Diseases |
| title |
Molecular Function and Regulation of Non-coding RNAs in Multifactorial Diseases |
| spellingShingle |
Molecular Function and Regulation of Non-coding RNAs in Multifactorial Diseases Genetics Science (General) Biomarker Long non -- Coding RNA Complex disease Mirna Cancer |
| title_short |
Molecular Function and Regulation of Non-coding RNAs in Multifactorial Diseases |
| title_full |
Molecular Function and Regulation of Non-coding RNAs in Multifactorial Diseases |
| title_fullStr |
Molecular Function and Regulation of Non-coding RNAs in Multifactorial Diseases |
| title_full_unstemmed |
Molecular Function and Regulation of Non-coding RNAs in Multifactorial Diseases |
| title_sort |
Molecular Function and Regulation of Non-coding RNAs in Multifactorial Diseases |
| dc.subject.spa.fl_str_mv |
Genetics Science (General) Biomarker |
| topic |
Genetics Science (General) Biomarker Long non -- Coding RNA Complex disease Mirna Cancer |
| dc.subject.lemb.spa.fl_str_mv |
Long non -- Coding RNA Complex disease |
| dc.subject.keyword.spa.fl_str_mv |
Mirna Cancer |
| description |
Our understanding of the mechanisms underlying the development of multifactorial diseases such as diabetes, autism, Alzheimer's disease, and cancer has been greatly advanced. Non-coding RNAs (ncRNAs), generally including microRNAs and long non-coding RNAs, have recently been found to have potential roles in these diseases, and provide new opportunities for developing both specific biomarkers and therapeutic targets. However, the molecular function and regulation of these RNAs still remains challenging. Numerous studies are focusing on this field in order to fully appreciate the role and regulation of these molecules in human medicine and biology. This e-book aims to bring together new findings on Non-coding RNAs in different complex diseases. It will highlight the characterization, roles, mechanism, and mode of action of these RNAs in complex disorders. We believe that the publications on this topic would be exponentially extended in future. The improved approaches at multiple levels may pave the way for designing and applying new biomarker and therapeutic targets for specific diseases based on these attractive molecules. |
| publishDate |
2016 |
| dc.date.created.none.fl_str_mv |
2016 |
| dc.date.accessioned.none.fl_str_mv |
2020-10-09T21:59:24Z |
| dc.date.available.none.fl_str_mv |
2020-10-09T21:59:24Z |
| dc.type.local.spa.fl_str_mv |
Libro |
| dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_2f33 |
| format |
http://purl.org/coar/resource_type/c_2f33 |
| dc.identifier.isbn.none.fl_str_mv |
978-2-889-45002-2 |
| dc.identifier.issn.none.fl_str_mv |
1664-8714 |
| dc.identifier.other.none.fl_str_mv |
https://www.frontiersin.org/research-topics/3338/molecular-function-and-regulation-of-non-coding-rnas-in-multifactorial-diseases |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/20.500.12010/14332 |
| dc.identifier.doi.none.fl_str_mv |
10.3389/978-2-88945-002-2 |
| identifier_str_mv |
978-2-889-45002-2 1664-8714 10.3389/978-2-88945-002-2 |
| url |
https://www.frontiersin.org/research-topics/3338/molecular-function-and-regulation-of-non-coding-rnas-in-multifactorial-diseases http://hdl.handle.net/20.500.12010/14332 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.references.spa.fl_str_mv |
Hajjari, M., Mowla, S. J., Faghihi, M. A., eds. (2016). Molecular Function and Regulation of Non-coding RNAs in Multifactorial Diseases. Lausanne: Frontiers Media. doi: 10.3389/978-2-88945-002-2 |
| dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
| dc.rights.local.spa.fl_str_mv |
Abierto (Texto Completo) |
| dc.rights.creativecommons.none.fl_str_mv |
https://creativecommons.org/licenses/by/4.0/ |
| rights_invalid_str_mv |
Abierto (Texto Completo) https://creativecommons.org/licenses/by/4.0/ http://purl.org/coar/access_right/c_abf2 |
| dc.format.extent.spa.fl_str_mv |
73 páginas |
| dc.format.mimetype.spa.fl_str_mv |
application/pdf |
| dc.publisher.spa.fl_str_mv |
Frontiers Media SA |
| institution |
Universidad de Bogotá Jorge Tadeo Lozano |
| bitstream.url.fl_str_mv |
https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14332/1/MOLECULAR%20FUNCTION_21.PDF https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14332/2/license.txt https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14332/3/MOLECULAR%20FUNCTION_21.PDF.jpg |
| bitstream.checksum.fl_str_mv |
6f477f7782dc91a598e631d9917de72f abceeb1c943c50d3343516f9dbfc110f eb66fed2bb345836c7d71d714a9a4567 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositorio Institucional - Universidad Jorge Tadeo Lozano |
| repository.mail.fl_str_mv |
expeditio@utadeo.edu.co |
| _version_ |
1808495225879920640 |
| spelling |
2020-10-09T21:59:24Z2020-10-09T21:59:24Z2016978-2-889-45002-21664-8714https://www.frontiersin.org/research-topics/3338/molecular-function-and-regulation-of-non-coding-rnas-in-multifactorial-diseaseshttp://hdl.handle.net/20.500.12010/1433210.3389/978-2-88945-002-273 páginasapplication/pdfengFrontiers Media SAGeneticsScience (General)BiomarkerLong non -- Coding RNAComplex diseaseMirnaCancerMolecular Function and Regulation of Non-coding RNAs in Multifactorial DiseasesLibrohttp://purl.org/coar/resource_type/c_2f33Abierto (Texto Completo)https://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_abf2Hajjari, M., Mowla, S. J., Faghihi, M. A., eds. (2016). Molecular Function and Regulation of Non-coding RNAs in Multifactorial Diseases. Lausanne: Frontiers Media. doi: 10.3389/978-2-88945-002-2Our understanding of the mechanisms underlying the development of multifactorial diseases such as diabetes, autism, Alzheimer's disease, and cancer has been greatly advanced. Non-coding RNAs (ncRNAs), generally including microRNAs and long non-coding RNAs, have recently been found to have potential roles in these diseases, and provide new opportunities for developing both specific biomarkers and therapeutic targets. However, the molecular function and regulation of these RNAs still remains challenging. Numerous studies are focusing on this field in order to fully appreciate the role and regulation of these molecules in human medicine and biology. This e-book aims to bring together new findings on Non-coding RNAs in different complex diseases. It will highlight the characterization, roles, mechanism, and mode of action of these RNAs in complex disorders. We believe that the publications on this topic would be exponentially extended in future. The improved approaches at multiple levels may pave the way for designing and applying new biomarker and therapeutic targets for specific diseases based on these attractive molecules.Hajjari, MohammadrezaMowla, Seyed JavadFaghihi, Mohammad AliORIGINALMOLECULAR FUNCTION_21.PDFMOLECULAR FUNCTION_21.PDFVer documentoapplication/pdf8762597https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14332/1/MOLECULAR%20FUNCTION_21.PDF6f477f7782dc91a598e631d9917de72fMD51open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-82938https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14332/2/license.txtabceeb1c943c50d3343516f9dbfc110fMD52open accessTHUMBNAILMOLECULAR FUNCTION_21.PDF.jpgMOLECULAR FUNCTION_21.PDF.jpgIM Thumbnailimage/jpeg24033https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14332/3/MOLECULAR%20FUNCTION_21.PDF.jpgeb66fed2bb345836c7d71d714a9a4567MD53open access20.500.12010/14332oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/143322021-02-22 18:21:54.616open accessRepositorio Institucional - Universidad Jorge Tadeo Lozanoexpeditio@utadeo.edu.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 |