COVID-19: Loss of bridging between innate and adaptive immunity?

COVID-19 has spread to most countries in the world. However, there are some striking differences in how COVID-19 is behaving in different age groups. While data on COVID-19 is limited, children appear to be less susceptible to severe disease. These unique characteristics may be considered as a poten...

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Autores:
Tipo de recurso:
Article of journal
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12111
Acceso en línea:
https://doi.org/10.1016/j.mehy.2020.109861
http://hdl.handle.net/20.500.12010/12111
Palabra clave:
COVID-19
SARS-CoV2
Adaptive immunity
Innate immunity
Cytokines
Interferons (IFNs)
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
Rights
License
Acceso restringido
id UTADEO2_4855732a34d76e063a350a64d7dc950b
oai_identifier_str oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12111
network_acronym_str UTADEO2
network_name_str Expeditio: repositorio UTadeo
repository_id_str
dc.title.spa.fl_str_mv COVID-19: Loss of bridging between innate and adaptive immunity?
title COVID-19: Loss of bridging between innate and adaptive immunity?
spellingShingle COVID-19: Loss of bridging between innate and adaptive immunity?
COVID-19
SARS-CoV2
Adaptive immunity
Innate immunity
Cytokines
Interferons (IFNs)
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
title_short COVID-19: Loss of bridging between innate and adaptive immunity?
title_full COVID-19: Loss of bridging between innate and adaptive immunity?
title_fullStr COVID-19: Loss of bridging between innate and adaptive immunity?
title_full_unstemmed COVID-19: Loss of bridging between innate and adaptive immunity?
title_sort COVID-19: Loss of bridging between innate and adaptive immunity?
dc.subject.spa.fl_str_mv COVID-19
SARS-CoV2
Adaptive immunity
Innate immunity
Cytokines
Interferons (IFNs)
topic COVID-19
SARS-CoV2
Adaptive immunity
Innate immunity
Cytokines
Interferons (IFNs)
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
dc.subject.lemb.spa.fl_str_mv Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
description COVID-19 has spread to most countries in the world. However, there are some striking differences in how COVID-19 is behaving in different age groups. While data on COVID-19 is limited, children appear to be less susceptible to severe disease. These unique characteristics may be considered as a potential link to understanding the immune system and response in COVID-19 and lead to an effective cure to the disease. We suggest a possible role of loss of bridging between innate and adaptive immunity in COVID-19 and a potential treatment modality also discussed.
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-08-21T20:33:51Z
dc.date.available.none.fl_str_mv 2020-08-21T20:33:51Z
dc.date.created.none.fl_str_mv 2020
dc.type.local.spa.fl_str_mv Artículo
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_6501
format http://purl.org/coar/resource_type/c_6501
dc.identifier.issn.spa.fl_str_mv 0306-9877
dc.identifier.other.spa.fl_str_mv https://doi.org/10.1016/j.mehy.2020.109861
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12010/12111
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1016/j.mehy.2020.109861
identifier_str_mv 0306-9877
url https://doi.org/10.1016/j.mehy.2020.109861
http://hdl.handle.net/20.500.12010/12111
dc.language.iso.spa.fl_str_mv eng
language eng
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dc.rights.local.spa.fl_str_mv Acceso restringido
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dc.format.extent.spa.fl_str_mv 2 páginas
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dc.publisher.spa.fl_str_mv Medical Hypotheses
dc.source.spa.fl_str_mv reponame:Expeditio Repositorio Institucional UJTL
instname:Universidad de Bogotá Jorge Tadeo Lozano
instname_str Universidad de Bogotá Jorge Tadeo Lozano
institution Universidad de Bogotá Jorge Tadeo Lozano
reponame_str Expeditio Repositorio Institucional UJTL
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spelling 2020-08-21T20:33:51Z2020-08-21T20:33:51Z20200306-9877https://doi.org/10.1016/j.mehy.2020.109861http://hdl.handle.net/20.500.12010/12111https://doi.org/10.1016/j.mehy.2020.109861COVID-19 has spread to most countries in the world. However, there are some striking differences in how COVID-19 is behaving in different age groups. While data on COVID-19 is limited, children appear to be less susceptible to severe disease. These unique characteristics may be considered as a potential link to understanding the immune system and response in COVID-19 and lead to an effective cure to the disease. We suggest a possible role of loss of bridging between innate and adaptive immunity in COVID-19 and a potential treatment modality also discussed.2 páginasimage/jepgengMedical Hypothesesreponame:Expeditio Repositorio Institucional UJTLinstname:Universidad de Bogotá Jorge Tadeo LozanoCOVID-19SARS-CoV2Adaptive immunityInnate immunityCytokinesInterferons (IFNs)Síndrome respiratorio agudo graveCOVID-19SARS-CoV-2CoronavirusCOVID-19: Loss of bridging between innate and adaptive immunity?Artículohttp://purl.org/coar/resource_type/c_6501Acceso restringidohttp://purl.org/coar/access_right/c_f1cfRao, Vishal U.SArakeri, GururajSubash, AnandRao, JyothsnaSachin Jadhav, Sachin JadhavSuhail Sayeed, MuftiRao, GururajBrennan, Peter A.ORIGINALCaptura.PNGCaptura.PNGVer portadaimage/png130628https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12111/1/Captura.PNGe06a70179bd62c30c8b7508bcebda36dMD51open accessCOVID-19--Loss-of-bridging-between-innate-and-adaptive-_2020_Medical-Hypothe.pdfCOVID-19--Loss-of-bridging-between-innate-and-adaptive-_2020_Medical-Hypothe.pdfArtículo reservadoapplication/pdf165671https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12111/3/COVID-19--Loss-of-bridging-between-innate-and-adaptive-_2020_Medical-Hypothe.pdf074c1bdcd191e59031845bab20624338MD53embargoed access|||2200-08-21LICENSElicense.txtlicense.txttext/plain; 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