Re-positive COVID-19 PCR test: could it be a reinfection?
The coronavirus disease 2019 (COVID-19) outbreak started in December 2019 and rapidly spread around the globe as a major health threat. Several reports on re-positive cases subsequent to discharge from hospitals caught our attention. We aimed to highlight real-time polymerase chain reaction (RT-qPCR...
- Autores:
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2020
- Institución:
- Universidad de Bogotá Jorge Tadeo Lozano
- Repositorio:
- Expeditio: repositorio UTadeo
- Idioma:
- eng
- OAI Identifier:
- oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12247
- Acceso en línea:
- https://doi.org/10.1016/j.nmni.2020.100748
http://hdl.handle.net/20.500.12010/12247
- Palabra clave:
- COVID-19
False-negative
RT-qPCR
Low viral load
SARS-CoV-2
CT scan
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
- Rights
- License
- Abierto (Texto Completo)
| Summary: | The coronavirus disease 2019 (COVID-19) outbreak started in December 2019 and rapidly spread around the globe as a major health threat. Several reports on re-positive cases subsequent to discharge from hospitals caught our attention. We aimed to highlight real-time polymerase chain reaction (RT-qPCR) positivity re-detection after discharge from the isolation, with special consideration on possible reasons behind it. We found that re-positive RT-qPCR assays for SARS-CoV-2 after prior negative Results might be attributed to false-negative laboratory results and prolonged viral shedding, rather than re-infection. These findings are encouraging and should be validated in a larger cohort. |
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