It takes a village... Contending with drug shortages during disasters

The World Health Organization (WHO) designates access to essential drugs as a critical concern due to persistent shortages and escalating costs.1,2 Drug shortages are a function of demand and supply mismatches that can be affected by manufacturing, distribution, as well as regulatory, economic, or p...

Full description

Autores:
Tipo de recurso:
Article of investigation
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12489
Acceso en línea:
https://doi.org/10.1016/j.chest.2020.08.015
http://hdl.handle.net/20.500.12010/12489
Palabra clave:
Drug shortages
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
Rights
License
Acceso restringido
id UTADEO2_3e6e6afb08f553e0c0ddffd824067842
oai_identifier_str oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12489
network_acronym_str UTADEO2
network_name_str Expeditio: repositorio UTadeo
repository_id_str
dc.title.spa.fl_str_mv It takes a village... Contending with drug shortages during disasters
title It takes a village... Contending with drug shortages during disasters
spellingShingle It takes a village... Contending with drug shortages during disasters
Drug shortages
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
title_short It takes a village... Contending with drug shortages during disasters
title_full It takes a village... Contending with drug shortages during disasters
title_fullStr It takes a village... Contending with drug shortages during disasters
title_full_unstemmed It takes a village... Contending with drug shortages during disasters
title_sort It takes a village... Contending with drug shortages during disasters
dc.subject.spa.fl_str_mv Drug shortages
topic Drug shortages
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
dc.subject.lemb.spa.fl_str_mv Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
description The World Health Organization (WHO) designates access to essential drugs as a critical concern due to persistent shortages and escalating costs.1,2 Drug shortages are a function of demand and supply mismatches that can be affected by manufacturing, distribution, as well as regulatory, economic, or political considerations. Prior to the 2019 coronavirus disease (COVID-19) pandemic, numerous countries frequently documented such shortages, mostly with injectable drugs, to include antimicrobials, anaesthetics, cardiovascular and neurologic drugs, nutrition, electrolytes, and cancer chemotherapy.2,3 The COVID-19 pandemic dramatically demonstrates how large and sudden surge in demand can lead to shortages when local, national, and international supply chains cannot keep pace, in particular medications with limited therapeutic alternatives for critical care. We highlight the available literature on possible causes and mitigation strategies to manage shortages of critical care drugs from the local, institutional level to the global stage in a worldwide crisis such as a pandemic.
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-08-31T19:27:23Z
dc.date.available.none.fl_str_mv 2020-08-31T19:27:23Z
dc.date.created.none.fl_str_mv 2020
dc.type.local.spa.fl_str_mv Artículo
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
format http://purl.org/coar/resource_type/c_2df8fbb1
dc.identifier.issn.spa.fl_str_mv 0012-3692
dc.identifier.other.spa.fl_str_mv https://doi.org/10.1016/j.chest.2020.08.015
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12010/12489
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1016/j.chest.2020.08.015
identifier_str_mv 0012-3692
url https://doi.org/10.1016/j.chest.2020.08.015
http://hdl.handle.net/20.500.12010/12489
dc.language.iso.spa.fl_str_mv eng
language eng
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_f1cf
dc.rights.local.spa.fl_str_mv Acceso restringido
rights_invalid_str_mv Acceso restringido
http://purl.org/coar/access_right/c_f1cf
dc.format.extent.spa.fl_str_mv 23 páginas
dc.format.mimetype.spa.fl_str_mv image/jepg
dc.publisher.spa.fl_str_mv CHEST
dc.source.spa.fl_str_mv reponame:Expeditio Repositorio Institucional UJTL
instname:Universidad de Bogotá Jorge Tadeo Lozano
instname_str Universidad de Bogotá Jorge Tadeo Lozano
institution Universidad de Bogotá Jorge Tadeo Lozano
reponame_str Expeditio Repositorio Institucional UJTL
collection Expeditio Repositorio Institucional UJTL
bitstream.url.fl_str_mv https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12489/1/Captura.PNG
https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12489/3/It-Takes-a-Village--Contending-with-Drug-Shortages-During-Disaster_2020_Ches.pdf
https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12489/2/license.txt
https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12489/4/Captura.PNG
https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12489/5/It-Takes-a-Village--Contending-with-Drug-Shortages-During-Disaster_2020_Ches.pdf.jpg
bitstream.checksum.fl_str_mv cd73ea9f39fb9121c10a111de2a1d6d7
fec8e69082cb9a8898c356857dda5292
abceeb1c943c50d3343516f9dbfc110f
cd73ea9f39fb9121c10a111de2a1d6d7
ccb493b7050e389f3375dc4cf77d6880
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositorio Institucional - Universidad Jorge Tadeo Lozano
repository.mail.fl_str_mv expeditio@utadeo.edu.co
_version_ 1814213667382624256
spelling 2020-08-31T19:27:23Z2020-08-31T19:27:23Z20200012-3692https://doi.org/10.1016/j.chest.2020.08.015http://hdl.handle.net/20.500.12010/12489https://doi.org/10.1016/j.chest.2020.08.015The World Health Organization (WHO) designates access to essential drugs as a critical concern due to persistent shortages and escalating costs.1,2 Drug shortages are a function of demand and supply mismatches that can be affected by manufacturing, distribution, as well as regulatory, economic, or political considerations. Prior to the 2019 coronavirus disease (COVID-19) pandemic, numerous countries frequently documented such shortages, mostly with injectable drugs, to include antimicrobials, anaesthetics, cardiovascular and neurologic drugs, nutrition, electrolytes, and cancer chemotherapy.2,3 The COVID-19 pandemic dramatically demonstrates how large and sudden surge in demand can lead to shortages when local, national, and international supply chains cannot keep pace, in particular medications with limited therapeutic alternatives for critical care. We highlight the available literature on possible causes and mitigation strategies to manage shortages of critical care drugs from the local, institutional level to the global stage in a worldwide crisis such as a pandemic.23 páginasimage/jepgengCHESTreponame:Expeditio Repositorio Institucional UJTLinstname:Universidad de Bogotá Jorge Tadeo LozanoDrug shortagesSíndrome respiratorio agudo graveCOVID-19SARS-CoV-2CoronavirusIt takes a village... Contending with drug shortages during disastersArtículohttp://purl.org/coar/resource_type/c_2df8fbb1Acceso restringidohttp://purl.org/coar/access_right/c_f1cfBurry, Lisa D.Barletta, Jeffrey F.Williamson, DavidKanji, SalmaanMaves, Ryan C.Dichter, JeffreyChristian, Michael D.Geiling, JamesErstad, Brian L.ORIGINALCaptura.PNGCaptura.PNGVer portadaimage/png112209https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12489/1/Captura.PNGcd73ea9f39fb9121c10a111de2a1d6d7MD51open accessIt-Takes-a-Village--Contending-with-Drug-Shortages-During-Disaster_2020_Ches.pdfIt-Takes-a-Village--Contending-with-Drug-Shortages-During-Disaster_2020_Ches.pdfArtículo reservadoapplication/pdf1688330https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12489/3/It-Takes-a-Village--Contending-with-Drug-Shortages-During-Disaster_2020_Ches.pdffec8e69082cb9a8898c356857dda5292MD53embargoed access|||2200-08-31LICENSElicense.txtlicense.txttext/plain; charset=utf-82938https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12489/2/license.txtabceeb1c943c50d3343516f9dbfc110fMD52open accessTHUMBNAILCaptura.PNGCaptura.PNGPortadaimage/png112209https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12489/4/Captura.PNGcd73ea9f39fb9121c10a111de2a1d6d7MD54open accessIt-Takes-a-Village--Contending-with-Drug-Shortages-During-Disaster_2020_Ches.pdf.jpgIt-Takes-a-Village--Contending-with-Drug-Shortages-During-Disaster_2020_Ches.pdf.jpgIM Thumbnailimage/jpeg11962https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12489/5/It-Takes-a-Village--Contending-with-Drug-Shortages-During-Disaster_2020_Ches.pdf.jpgccb493b7050e389f3375dc4cf77d6880MD55open access20.500.12010/12489oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/124892020-08-31 14:27:23.67open accessRepositorio Institucional - Universidad Jorge Tadeo Lozanoexpeditio@utadeo.edu.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