Neural and Synaptic Defects in Autism Spectrum Disorders

Autism spectrum disorders (ASDs) are a group of genetically and clinically heterogeneous neurodevelopmental disorders characterized by impaired reciprocal social interactions and communication, and restricted and repetitive patterns of behaviors and interests. Studies in genetics, neurobiology and s...

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Autores:
Tipo de recurso:
Book
Fecha de publicación:
2015
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/14446
Acceso en línea:
https://www.frontiersin.org/research-topics/1273/neural-and-synaptic-defects-in-autism-spectrum-disorders
http://hdl.handle.net/20.500.12010/14446
Palabra clave:
Neurología
Trastornos del espectro autista
Síndrome de Rett
Déficits sinápticos
Rights
License
Abierto (Texto Completo)
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dc.title.spa.fl_str_mv Neural and Synaptic Defects in Autism Spectrum Disorders
title Neural and Synaptic Defects in Autism Spectrum Disorders
spellingShingle Neural and Synaptic Defects in Autism Spectrum Disorders
Neurología
Trastornos del espectro autista
Síndrome de Rett
Déficits sinápticos
title_short Neural and Synaptic Defects in Autism Spectrum Disorders
title_full Neural and Synaptic Defects in Autism Spectrum Disorders
title_fullStr Neural and Synaptic Defects in Autism Spectrum Disorders
title_full_unstemmed Neural and Synaptic Defects in Autism Spectrum Disorders
title_sort Neural and Synaptic Defects in Autism Spectrum Disorders
dc.subject.spa.fl_str_mv Neurología
topic Neurología
Trastornos del espectro autista
Síndrome de Rett
Déficits sinápticos
dc.subject.lemb.spa.fl_str_mv Trastornos del espectro autista
Síndrome de Rett
Déficits sinápticos
description Autism spectrum disorders (ASDs) are a group of genetically and clinically heterogeneous neurodevelopmental disorders characterized by impaired reciprocal social interactions and communication, and restricted and repetitive patterns of behaviors and interests. Studies in genetics, neurobiology and systems biology are providing insights into the pathogenesis of ASDs. Investigation of neural and synaptic defects in ASDs not only sheds light on the molecular and cellular mechanisms that govern the function of the central nervous system, but may lead to the discovery of potential therapeutic targets for autism and other cognitive disorders. Our Research Topic which constitutes this e-book documents the recent development and ideas in the study of pathogenesis and treatment of ASDs, with an emphasis on syndromic disorders such as fragile X and Rett syndromes. In addition, model systems and methodological approaches with translational relevance to autism are covered herein. We hope that the Research Topic will enhance the global knowledge base in the autism research community and foster new research directions in autism related biology.
publishDate 2015
dc.date.created.none.fl_str_mv 2015
dc.date.accessioned.none.fl_str_mv 2020-10-13T23:54:40Z
dc.date.available.none.fl_str_mv 2020-10-13T23:54:40Z
dc.type.local.spa.fl_str_mv Libro
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2f33
format http://purl.org/coar/resource_type/c_2f33
dc.identifier.isbn.none.fl_str_mv 978-2-889-19628-9
dc.identifier.issn.none.fl_str_mv 1664-8714
dc.identifier.other.none.fl_str_mv https://www.frontiersin.org/research-topics/1273/neural-and-synaptic-defects-in-autism-spectrum-disorders
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12010/14446
dc.identifier.doi.none.fl_str_mv 10.3389/978-2-88919-628-9
identifier_str_mv 978-2-889-19628-9
1664-8714
10.3389/978-2-88919-628-9
url https://www.frontiersin.org/research-topics/1273/neural-and-synaptic-defects-in-autism-spectrum-disorders
http://hdl.handle.net/20.500.12010/14446
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.references.none.fl_str_mv Wang, H., Doering, L. C., eds. (2015). Neural and Synaptic Defects in Autism Spectrum Disorders. Lausanne: Frontiers Media. doi: 10.3389/978-2-88919-628-9
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.local.spa.fl_str_mv Abierto (Texto Completo)
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rights_invalid_str_mv Abierto (Texto Completo)
https://creativecommons.org/licenses/by/4.0/legalcode
http://purl.org/coar/access_right/c_abf2
dc.format.extent.spa.fl_str_mv 287 páginas
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Frontiers Media SA
institution Universidad de Bogotá Jorge Tadeo Lozano
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spelling 2020-10-13T23:54:40Z2020-10-13T23:54:40Z2015978-2-889-19628-91664-8714https://www.frontiersin.org/research-topics/1273/neural-and-synaptic-defects-in-autism-spectrum-disordershttp://hdl.handle.net/20.500.12010/1444610.3389/978-2-88919-628-9287 páginasapplication/pdfengFrontiers Media SANeurologíaTrastornos del espectro autistaSíndrome de RettDéficits sinápticosNeural and Synaptic Defects in Autism Spectrum DisordersLibrohttp://purl.org/coar/resource_type/c_2f33Abierto (Texto Completo)https://creativecommons.org/licenses/by/4.0/legalcodehttp://purl.org/coar/access_right/c_abf2Wang, H., Doering, L. C., eds. (2015). Neural and Synaptic Defects in Autism Spectrum Disorders. Lausanne: Frontiers Media. doi: 10.3389/978-2-88919-628-9Autism spectrum disorders (ASDs) are a group of genetically and clinically heterogeneous neurodevelopmental disorders characterized by impaired reciprocal social interactions and communication, and restricted and repetitive patterns of behaviors and interests. Studies in genetics, neurobiology and systems biology are providing insights into the pathogenesis of ASDs. Investigation of neural and synaptic defects in ASDs not only sheds light on the molecular and cellular mechanisms that govern the function of the central nervous system, but may lead to the discovery of potential therapeutic targets for autism and other cognitive disorders. Our Research Topic which constitutes this e-book documents the recent development and ideas in the study of pathogenesis and treatment of ASDs, with an emphasis on syndromic disorders such as fragile X and Rett syndromes. In addition, model systems and methodological approaches with translational relevance to autism are covered herein. We hope that the Research Topic will enhance the global knowledge base in the autism research community and foster new research directions in autism related biology.Wang, HansenDoering, Laurie C.ORIGINALNeural and Synaptic Defects in Autism Spectrum Disorders_78.PDFNeural and Synaptic Defects in Autism Spectrum Disorders_78.PDFVer documentoapplication/pdf29100881https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14446/1/Neural%20and%20Synaptic%20Defects%20in%20Autism%20Spectrum%20Disorders_78.PDF1a58868d65bcc7b04d4cc596ad2b66faMD51open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-82938https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14446/2/license.txtabceeb1c943c50d3343516f9dbfc110fMD52open accessTHUMBNAILNeural and Synaptic Defects in Autism Spectrum Disorders_78.PDF.jpgNeural and Synaptic Defects in Autism Spectrum Disorders_78.PDF.jpgIM Thumbnailimage/jpeg26766https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/14446/3/Neural%20and%20Synaptic%20Defects%20in%20Autism%20Spectrum%20Disorders_78.PDF.jpgf99568f1f61cdd416a291135167777aeMD53open access20.500.12010/14446oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/144462021-01-14 20:54:59.138open accessRepositorio Institucional - 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