COVID-19: beta-thalassemia subjects immunised?

The novel coronavirus pneumonia (COVID-19) is a contagious acute respiratory infectious disease whose causative agent has been demonstrated to be a novel virus of the coronavirus family, SARSCoV-2. A recent PRE-print study has showed a heme attack on the 1-beta chain of hemoglobin by COVID19. Beta-t...

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Autores:
Tipo de recurso:
Article of journal
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12112
Acceso en línea:
https://doi.org/10.1016/j.mehy.2020.109827
http://hdl.handle.net/20.500.12010/12112
Palabra clave:
Novel coronavirus
Respiratory distress
Favipiravir
Statistics
Correlation
Beta thalassemia
Immunization
Italy
Sardinia
Regression
Heme
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
Rights
License
Acceso restringido
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repository_id_str
dc.title.spa.fl_str_mv COVID-19: beta-thalassemia subjects immunised?
title COVID-19: beta-thalassemia subjects immunised?
spellingShingle COVID-19: beta-thalassemia subjects immunised?
Novel coronavirus
Respiratory distress
Favipiravir
Statistics
Correlation
Beta thalassemia
Immunization
Italy
Sardinia
Regression
Heme
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
title_short COVID-19: beta-thalassemia subjects immunised?
title_full COVID-19: beta-thalassemia subjects immunised?
title_fullStr COVID-19: beta-thalassemia subjects immunised?
title_full_unstemmed COVID-19: beta-thalassemia subjects immunised?
title_sort COVID-19: beta-thalassemia subjects immunised?
dc.subject.spa.fl_str_mv Novel coronavirus
Respiratory distress
Favipiravir
Statistics
Correlation
Beta thalassemia
Immunization
Italy
Sardinia
Regression
Heme
topic Novel coronavirus
Respiratory distress
Favipiravir
Statistics
Correlation
Beta thalassemia
Immunization
Italy
Sardinia
Regression
Heme
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
dc.subject.lemb.spa.fl_str_mv Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
description The novel coronavirus pneumonia (COVID-19) is a contagious acute respiratory infectious disease whose causative agent has been demonstrated to be a novel virus of the coronavirus family, SARSCoV-2. A recent PRE-print study has showed a heme attack on the 1-beta chain of hemoglobin by COVID19. Beta-thalassemia results of a default in the hemoglobin beta-chain synthesis. 1,5% global population are heterozygotes for this disease. In this study, by a multiple linear regression, we have analyzed the evolution of COVID-19 infection in three Italian regions (Puglia, Sardinia, Sicilia) with different beta-thalassemic prevalences, in order to search a link. The results have showed that betathalassemic heterozygote population prevalence is correlated to immunity against COVID-19, by a regression. This paper is only for academic discussion, the hypotheses and conclusions needs to be confirmed by further research.
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-08-21T20:41:52Z
dc.date.available.none.fl_str_mv 2020-08-21T20:41:52Z
dc.date.created.none.fl_str_mv 2020
dc.type.local.spa.fl_str_mv Artículo
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dc.identifier.issn.spa.fl_str_mv 0306-9877
dc.identifier.other.spa.fl_str_mv https://doi.org/10.1016/j.mehy.2020.109827
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12010/12112
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1016/j.mehy.2020.109827
identifier_str_mv 0306-9877
url https://doi.org/10.1016/j.mehy.2020.109827
http://hdl.handle.net/20.500.12010/12112
dc.language.iso.spa.fl_str_mv eng
language eng
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dc.rights.local.spa.fl_str_mv Acceso restringido
rights_invalid_str_mv Acceso restringido
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dc.format.extent.spa.fl_str_mv 5 páginas
dc.format.mimetype.spa.fl_str_mv image/jepg
dc.publisher.spa.fl_str_mv Medical Hypotheses
dc.source.spa.fl_str_mv reponame:Expeditio Repositorio Institucional UJTL
instname:Universidad de Bogotá Jorge Tadeo Lozano
instname_str Universidad de Bogotá Jorge Tadeo Lozano
institution Universidad de Bogotá Jorge Tadeo Lozano
reponame_str Expeditio Repositorio Institucional UJTL
collection Expeditio Repositorio Institucional UJTL
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spelling 2020-08-21T20:41:52Z2020-08-21T20:41:52Z20200306-9877https://doi.org/10.1016/j.mehy.2020.109827http://hdl.handle.net/20.500.12010/12112https://doi.org/10.1016/j.mehy.2020.109827The novel coronavirus pneumonia (COVID-19) is a contagious acute respiratory infectious disease whose causative agent has been demonstrated to be a novel virus of the coronavirus family, SARSCoV-2. A recent PRE-print study has showed a heme attack on the 1-beta chain of hemoglobin by COVID19. Beta-thalassemia results of a default in the hemoglobin beta-chain synthesis. 1,5% global population are heterozygotes for this disease. In this study, by a multiple linear regression, we have analyzed the evolution of COVID-19 infection in three Italian regions (Puglia, Sardinia, Sicilia) with different beta-thalassemic prevalences, in order to search a link. The results have showed that betathalassemic heterozygote population prevalence is correlated to immunity against COVID-19, by a regression. This paper is only for academic discussion, the hypotheses and conclusions needs to be confirmed by further research.5 páginasimage/jepgengMedical Hypothesesreponame:Expeditio Repositorio Institucional UJTLinstname:Universidad de Bogotá Jorge Tadeo LozanoNovel coronavirusRespiratory distressFavipiravirStatisticsCorrelationBeta thalassemiaImmunizationItalySardiniaRegressionHemeSíndrome respiratorio agudo graveCOVID-19SARS-CoV-2CoronavirusCOVID-19: beta-thalassemia subjects immunised?Artículohttp://purl.org/coar/resource_type/c_6501Acceso restringidohttp://purl.org/coar/access_right/c_f1cfLansiaux, EdouardPierre Pébaÿ, PhilippePicard, Jean-LaurentSon-Forget, JoachimORIGINALCaptura.PNGCaptura.PNGVer portadaimage/png134020https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12112/1/Captura.PNG8a2a5325335ce1188aa090d8658d1b63MD51open accessCOVID-19--beta-thalassemia-subjects-immunised-_2020_Medical-Hypotheses.pdfCOVID-19--beta-thalassemia-subjects-immunised-_2020_Medical-Hypotheses.pdfArtículo reservadoapplication/pdf2569385https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12112/3/COVID-19--beta-thalassemia-subjects-immunised-_2020_Medical-Hypotheses.pdf0b710df49e82dde8281982688524710dMD53embargoed access|||2200-08-21LICENSElicense.txtlicense.txttext/plain; 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