Targets and strategies for vaccine development against SARS-CoV-2
The SARS-CoV-2, previously called a novel coronavirus, that broke out in the Wuhan city of China caused a significant number of morbidity and mortality in the world. It is spreading at peak levels since the first case reported and the need for vaccines is in immense demand globally. Numerous treatme...
- Autores:
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2021
- Institución:
- Universidad de Bogotá Jorge Tadeo Lozano
- Repositorio:
- Expeditio: repositorio UTadeo
- Idioma:
- eng
- OAI Identifier:
- oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/17030
- Acceso en línea:
- https://www.sciencedirect.com/science/article/pii/S0753332221000391?dgcid=raven_sd_search_email
http://hdl.handle.net/20.500.12010/17030
https://doi.org/10.1016/j.biopha.2021.111254
- Palabra clave:
- SARS-CoV-2
COVID-19
Clinical trials
SARS-CoV-2
Vaccine
Pandemic Antigen
- Rights
- License
- Abierto (Texto Completo)
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dc.title.spa.fl_str_mv |
Targets and strategies for vaccine development against SARS-CoV-2 |
title |
Targets and strategies for vaccine development against SARS-CoV-2 |
spellingShingle |
Targets and strategies for vaccine development against SARS-CoV-2 SARS-CoV-2 COVID-19 Clinical trials SARS-CoV-2 Vaccine Pandemic Antigen |
title_short |
Targets and strategies for vaccine development against SARS-CoV-2 |
title_full |
Targets and strategies for vaccine development against SARS-CoV-2 |
title_fullStr |
Targets and strategies for vaccine development against SARS-CoV-2 |
title_full_unstemmed |
Targets and strategies for vaccine development against SARS-CoV-2 |
title_sort |
Targets and strategies for vaccine development against SARS-CoV-2 |
dc.subject.spa.fl_str_mv |
SARS-CoV-2 |
topic |
SARS-CoV-2 COVID-19 Clinical trials SARS-CoV-2 Vaccine Pandemic Antigen |
dc.subject.keyword.spa.fl_str_mv |
COVID-19 Clinical trials SARS-CoV-2 Vaccine Pandemic Antigen |
description |
The SARS-CoV-2, previously called a novel coronavirus, that broke out in the Wuhan city of China caused a significant number of morbidity and mortality in the world. It is spreading at peak levels since the first case reported and the need for vaccines is in immense demand globally. Numerous treatment and vaccination strategies that were previously employed for other pathogens including coronaviruses are now beingbeen adopted to guide the formulation of new SARS-CoV-2 vaccines.Several vaccine targets can be utilized for the development ofthe SARS-CoV-2 vaccine. In this review, wehighlightedthe potential of various antigenic targets and other modes of formulating an effective vaccine against SARS-CoV-2. There are a varying number of challenges encountered during developing the most effective vaccines, andmeasures for tackling such challenges will assist in fast pace development of vaccines. This review will give a concise overview of various aspects of the vaccine development process against SARS-CoV-2 including 1) potential antigen targets 2) different vaccination strategies from conventional to novel platforms, 3) ongoing clinical trials, 4) varying challenges encountered during developing the most effective vaccine and the futuristicapproaches. |
publishDate |
2021 |
dc.date.accessioned.none.fl_str_mv |
2021-02-04T02:13:01Z |
dc.date.available.none.fl_str_mv |
2021-02-04T02:13:01Z |
dc.date.created.none.fl_str_mv |
2021 |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
format |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.identifier.other.spa.fl_str_mv |
https://www.sciencedirect.com/science/article/pii/S0753332221000391?dgcid=raven_sd_search_email |
dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/20.500.12010/17030 |
dc.identifier.doi.spa.fl_str_mv |
https://doi.org/10.1016/j.biopha.2021.111254 |
url |
https://www.sciencedirect.com/science/article/pii/S0753332221000391?dgcid=raven_sd_search_email http://hdl.handle.net/20.500.12010/17030 https://doi.org/10.1016/j.biopha.2021.111254 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.rights.local.spa.fl_str_mv |
Abierto (Texto Completo) |
rights_invalid_str_mv |
Abierto (Texto Completo) http://purl.org/coar/access_right/c_abf2 |
dc.format.extent.spa.fl_str_mv |
46 páginas |
dc.format.mimetype.spa.fl_str_mv |
application/pdf |
dc.publisher.spa.fl_str_mv |
Elsevier |
institution |
Universidad de Bogotá Jorge Tadeo Lozano |
bitstream.url.fl_str_mv |
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bitstream.checksumAlgorithm.fl_str_mv |
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repository.name.fl_str_mv |
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repository.mail.fl_str_mv |
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spelling |
2021-02-04T02:13:01Z2021-02-04T02:13:01Z2021https://www.sciencedirect.com/science/article/pii/S0753332221000391?dgcid=raven_sd_search_emailhttp://hdl.handle.net/20.500.12010/17030https://doi.org/10.1016/j.biopha.2021.11125446 páginasapplication/pdfengElsevierSARS-CoV-2COVID-19Clinical trialsSARS-CoV-2VaccinePandemic AntigenTargets and strategies for vaccine development against SARS-CoV-2Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2The SARS-CoV-2, previously called a novel coronavirus, that broke out in the Wuhan city of China caused a significant number of morbidity and mortality in the world. It is spreading at peak levels since the first case reported and the need for vaccines is in immense demand globally. Numerous treatment and vaccination strategies that were previously employed for other pathogens including coronaviruses are now beingbeen adopted to guide the formulation of new SARS-CoV-2 vaccines.Several vaccine targets can be utilized for the development ofthe SARS-CoV-2 vaccine. In this review, wehighlightedthe potential of various antigenic targets and other modes of formulating an effective vaccine against SARS-CoV-2. There are a varying number of challenges encountered during developing the most effective vaccines, andmeasures for tackling such challenges will assist in fast pace development of vaccines. This review will give a concise overview of various aspects of the vaccine development process against SARS-CoV-2 including 1) potential antigen targets 2) different vaccination strategies from conventional to novel platforms, 3) ongoing clinical trials, 4) varying challenges encountered during developing the most effective vaccine and the futuristicapproaches.http://purl.org/coar/resource_type/c_2df8fbb1Jonaid Ahmad, MalikAlmas Hanif, MullaTahmeena, FarooqiFaheem Hyder, PottooSirajudheen, AnwarKannan R.R., RengasamyORIGINAL1-s2.0-S0753332221000391-main.pdf1-s2.0-S0753332221000391-main.pdfVer documentoapplication/pdf4193300https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/17030/1/1-s2.0-S0753332221000391-main.pdf047d8141dc61068b58703495b051c2c2MD51open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-82938https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/17030/2/license.txtabceeb1c943c50d3343516f9dbfc110fMD52open accessTHUMBNAIL1-s2.0-S0753332221000391-main.pdf.jpg1-s2.0-S0753332221000391-main.pdf.jpgIM Thumbnailimage/jpeg6090https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/17030/3/1-s2.0-S0753332221000391-main.pdf.jpga0b0b6fec0e902738d0f8c185bfbec7eMD53open access20.500.12010/17030oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/170302021-02-03 21:55:49.327open accessRepositorio Institucional - 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