Targets and strategies for vaccine development against SARS-CoV-2

The SARS-CoV-2, previously called a novel coronavirus, that broke out in the Wuhan city of China caused a significant number of morbidity and mortality in the world. It is spreading at peak levels since the first case reported and the need for vaccines is in immense demand globally. Numerous treatme...

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Autores:
Tipo de recurso:
Article of investigation
Fecha de publicación:
2021
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/17030
Acceso en línea:
https://www.sciencedirect.com/science/article/pii/S0753332221000391?dgcid=raven_sd_search_email
http://hdl.handle.net/20.500.12010/17030
https://doi.org/10.1016/j.biopha.2021.111254
Palabra clave:
SARS-CoV-2
COVID-19
Clinical trials
SARS-CoV-2
Vaccine
Pandemic Antigen
Rights
License
Abierto (Texto Completo)
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dc.title.spa.fl_str_mv Targets and strategies for vaccine development against SARS-CoV-2
title Targets and strategies for vaccine development against SARS-CoV-2
spellingShingle Targets and strategies for vaccine development against SARS-CoV-2
SARS-CoV-2
COVID-19
Clinical trials
SARS-CoV-2
Vaccine
Pandemic Antigen
title_short Targets and strategies for vaccine development against SARS-CoV-2
title_full Targets and strategies for vaccine development against SARS-CoV-2
title_fullStr Targets and strategies for vaccine development against SARS-CoV-2
title_full_unstemmed Targets and strategies for vaccine development against SARS-CoV-2
title_sort Targets and strategies for vaccine development against SARS-CoV-2
dc.subject.spa.fl_str_mv SARS-CoV-2
topic SARS-CoV-2
COVID-19
Clinical trials
SARS-CoV-2
Vaccine
Pandemic Antigen
dc.subject.keyword.spa.fl_str_mv COVID-19
Clinical trials
SARS-CoV-2
Vaccine
Pandemic Antigen
description The SARS-CoV-2, previously called a novel coronavirus, that broke out in the Wuhan city of China caused a significant number of morbidity and mortality in the world. It is spreading at peak levels since the first case reported and the need for vaccines is in immense demand globally. Numerous treatment and vaccination strategies that were previously employed for other pathogens including coronaviruses are now beingbeen adopted to guide the formulation of new SARS-CoV-2 vaccines.Several vaccine targets can be utilized for the development ofthe SARS-CoV-2 vaccine. In this review, wehighlightedthe potential of various antigenic targets and other modes of formulating an effective vaccine against SARS-CoV-2. There are a varying number of challenges encountered during developing the most effective vaccines, andmeasures for tackling such challenges will assist in fast pace development of vaccines. This review will give a concise overview of various aspects of the vaccine development process against SARS-CoV-2 including 1) potential antigen targets 2) different vaccination strategies from conventional to novel platforms, 3) ongoing clinical trials, 4) varying challenges encountered during developing the most effective vaccine and the futuristicapproaches.
publishDate 2021
dc.date.accessioned.none.fl_str_mv 2021-02-04T02:13:01Z
dc.date.available.none.fl_str_mv 2021-02-04T02:13:01Z
dc.date.created.none.fl_str_mv 2021
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
format http://purl.org/coar/resource_type/c_2df8fbb1
dc.identifier.other.spa.fl_str_mv https://www.sciencedirect.com/science/article/pii/S0753332221000391?dgcid=raven_sd_search_email
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12010/17030
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1016/j.biopha.2021.111254
url https://www.sciencedirect.com/science/article/pii/S0753332221000391?dgcid=raven_sd_search_email
http://hdl.handle.net/20.500.12010/17030
https://doi.org/10.1016/j.biopha.2021.111254
dc.language.iso.spa.fl_str_mv eng
language eng
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.local.spa.fl_str_mv Abierto (Texto Completo)
rights_invalid_str_mv Abierto (Texto Completo)
http://purl.org/coar/access_right/c_abf2
dc.format.extent.spa.fl_str_mv 46 páginas
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Elsevier
institution Universidad de Bogotá Jorge Tadeo Lozano
bitstream.url.fl_str_mv https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/17030/1/1-s2.0-S0753332221000391-main.pdf
https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/17030/2/license.txt
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spelling 2021-02-04T02:13:01Z2021-02-04T02:13:01Z2021https://www.sciencedirect.com/science/article/pii/S0753332221000391?dgcid=raven_sd_search_emailhttp://hdl.handle.net/20.500.12010/17030https://doi.org/10.1016/j.biopha.2021.11125446 páginasapplication/pdfengElsevierSARS-CoV-2COVID-19Clinical trialsSARS-CoV-2VaccinePandemic AntigenTargets and strategies for vaccine development against SARS-CoV-2Abierto (Texto Completo)http://purl.org/coar/access_right/c_abf2The SARS-CoV-2, previously called a novel coronavirus, that broke out in the Wuhan city of China caused a significant number of morbidity and mortality in the world. It is spreading at peak levels since the first case reported and the need for vaccines is in immense demand globally. Numerous treatment and vaccination strategies that were previously employed for other pathogens including coronaviruses are now beingbeen adopted to guide the formulation of new SARS-CoV-2 vaccines.Several vaccine targets can be utilized for the development ofthe SARS-CoV-2 vaccine. In this review, wehighlightedthe potential of various antigenic targets and other modes of formulating an effective vaccine against SARS-CoV-2. There are a varying number of challenges encountered during developing the most effective vaccines, andmeasures for tackling such challenges will assist in fast pace development of vaccines. This review will give a concise overview of various aspects of the vaccine development process against SARS-CoV-2 including 1) potential antigen targets 2) different vaccination strategies from conventional to novel platforms, 3) ongoing clinical trials, 4) varying challenges encountered during developing the most effective vaccine and the futuristicapproaches.http://purl.org/coar/resource_type/c_2df8fbb1Jonaid Ahmad, MalikAlmas Hanif, MullaTahmeena, FarooqiFaheem Hyder, PottooSirajudheen, AnwarKannan R.R., RengasamyORIGINAL1-s2.0-S0753332221000391-main.pdf1-s2.0-S0753332221000391-main.pdfVer documentoapplication/pdf4193300https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/17030/1/1-s2.0-S0753332221000391-main.pdf047d8141dc61068b58703495b051c2c2MD51open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-82938https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/17030/2/license.txtabceeb1c943c50d3343516f9dbfc110fMD52open accessTHUMBNAIL1-s2.0-S0753332221000391-main.pdf.jpg1-s2.0-S0753332221000391-main.pdf.jpgIM Thumbnailimage/jpeg6090https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/17030/3/1-s2.0-S0753332221000391-main.pdf.jpga0b0b6fec0e902738d0f8c185bfbec7eMD53open access20.500.12010/17030oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/170302021-02-03 21:55:49.327open accessRepositorio Institucional - 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