Microwave- and heat-based decontamination of n95 filtering facepiece respirators: A systematic review

Background: In pandemics such as COVID-19, shortages of personal protective equipment are common. One solution may be to decontaminate equipment such as facemasks for reuse. Aim: To collect and synthesize existing information on decontamination of N95 filtering facepiece respirators (FFRs) using mic...

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Autores:
Tipo de recurso:
Article of investigation
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12332
Acceso en línea:
https://doi.org/10.1016/j.jhin.2020.08.016
http://hdl.handle.net/20.500.12010/12332
Palabra clave:
Personal Protective Equipment
N95
Filtering Facepiece Respirator
Decontamination
Pandemic
COVID-19
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
Rights
License
Acceso restringido
id UTADEO2_0804a7d72064a0f7eb06e68e2b401f6e
oai_identifier_str oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12332
network_acronym_str UTADEO2
network_name_str Expeditio: repositorio UTadeo
repository_id_str
dc.title.spa.fl_str_mv Microwave- and heat-based decontamination of n95 filtering facepiece respirators: A systematic review
title Microwave- and heat-based decontamination of n95 filtering facepiece respirators: A systematic review
spellingShingle Microwave- and heat-based decontamination of n95 filtering facepiece respirators: A systematic review
Personal Protective Equipment
N95
Filtering Facepiece Respirator
Decontamination
Pandemic
COVID-19
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
title_short Microwave- and heat-based decontamination of n95 filtering facepiece respirators: A systematic review
title_full Microwave- and heat-based decontamination of n95 filtering facepiece respirators: A systematic review
title_fullStr Microwave- and heat-based decontamination of n95 filtering facepiece respirators: A systematic review
title_full_unstemmed Microwave- and heat-based decontamination of n95 filtering facepiece respirators: A systematic review
title_sort Microwave- and heat-based decontamination of n95 filtering facepiece respirators: A systematic review
dc.subject.spa.fl_str_mv Personal Protective Equipment
N95
Filtering Facepiece Respirator
Decontamination
Pandemic
COVID-19
topic Personal Protective Equipment
N95
Filtering Facepiece Respirator
Decontamination
Pandemic
COVID-19
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
dc.subject.lemb.spa.fl_str_mv Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
description Background: In pandemics such as COVID-19, shortages of personal protective equipment are common. One solution may be to decontaminate equipment such as facemasks for reuse. Aim: To collect and synthesize existing information on decontamination of N95 filtering facepiece respirators (FFRs) using microwave and heat-based treatments, with special attention to impact on mask function (aerosol penetration, airflow resistance), fit, and physical traits. Methods: A systematic review (PROSPERO CRD42020177036) of literature available from Medline, Embase, Global Health, and other sources was conducted. Records were screened independently by two reviewers, and data was extracted from studies that reported on effects of microwave- or heat-based decontamination on N95 FFR performance, fit, physical traits, and/or reductions in microbial load. Findings: Thirteen studies were included that used dry/moist microwave irradiation, heat, or autoclaving. All treatment types reduced pathogen load by a log10 reduction factor of at least three when applied for sufficient duration (>30s microwave, >60 min dry heat), with most studies assessing viral pathogens. Mask function (aerosol penetration <5% and airflow resistance <25mmH2O) was preserved after all treatments except autoclaving. Fit was maintained for most N95 models, though all treatment types caused observable physical damage to at least one model. Conclusions: Microwave irradiation and heat may be safe and effective viral decontamination options for N95 FFR reuse during critical shortages. The evidence does not support autoclaving or high-heat (>90oC) approaches. Physical degradation may be an issue for certain mask models, and more real-world evidence on fit is needed.
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-08-26T19:38:12Z
dc.date.available.none.fl_str_mv 2020-08-26T19:38:12Z
dc.date.created.none.fl_str_mv 2020
dc.type.local.spa.fl_str_mv Artículo
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format http://purl.org/coar/resource_type/c_2df8fbb1
dc.identifier.issn.spa.fl_str_mv 0195-6701
dc.identifier.other.spa.fl_str_mv https://doi.org/10.1016/j.jhin.2020.08.016
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12010/12332
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1016/j.jhin.2020.08.016
identifier_str_mv 0195-6701
url https://doi.org/10.1016/j.jhin.2020.08.016
http://hdl.handle.net/20.500.12010/12332
dc.language.iso.spa.fl_str_mv eng
language eng
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_f1cf
dc.rights.local.spa.fl_str_mv Acceso restringido
rights_invalid_str_mv Acceso restringido
http://purl.org/coar/access_right/c_f1cf
dc.format.extent.spa.fl_str_mv 42 páginas
dc.format.mimetype.spa.fl_str_mv image/jepg
dc.publisher.spa.fl_str_mv Journal of Hospital Infection
dc.source.spa.fl_str_mv reponame:Expeditio Repositorio Institucional UJTL
instname:Universidad de Bogotá Jorge Tadeo Lozano
instname_str Universidad de Bogotá Jorge Tadeo Lozano
institution Universidad de Bogotá Jorge Tadeo Lozano
reponame_str Expeditio Repositorio Institucional UJTL
collection Expeditio Repositorio Institucional UJTL
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spelling 2020-08-26T19:38:12Z2020-08-26T19:38:12Z20200195-6701https://doi.org/10.1016/j.jhin.2020.08.016http://hdl.handle.net/20.500.12010/12332https://doi.org/10.1016/j.jhin.2020.08.016Background: In pandemics such as COVID-19, shortages of personal protective equipment are common. One solution may be to decontaminate equipment such as facemasks for reuse. Aim: To collect and synthesize existing information on decontamination of N95 filtering facepiece respirators (FFRs) using microwave and heat-based treatments, with special attention to impact on mask function (aerosol penetration, airflow resistance), fit, and physical traits. Methods: A systematic review (PROSPERO CRD42020177036) of literature available from Medline, Embase, Global Health, and other sources was conducted. Records were screened independently by two reviewers, and data was extracted from studies that reported on effects of microwave- or heat-based decontamination on N95 FFR performance, fit, physical traits, and/or reductions in microbial load. Findings: Thirteen studies were included that used dry/moist microwave irradiation, heat, or autoclaving. All treatment types reduced pathogen load by a log10 reduction factor of at least three when applied for sufficient duration (>30s microwave, >60 min dry heat), with most studies assessing viral pathogens. Mask function (aerosol penetration <5% and airflow resistance <25mmH2O) was preserved after all treatments except autoclaving. Fit was maintained for most N95 models, though all treatment types caused observable physical damage to at least one model. Conclusions: Microwave irradiation and heat may be safe and effective viral decontamination options for N95 FFR reuse during critical shortages. The evidence does not support autoclaving or high-heat (>90oC) approaches. Physical degradation may be an issue for certain mask models, and more real-world evidence on fit is needed.42 páginasimage/jepgengJournal of Hospital Infectionreponame:Expeditio Repositorio Institucional UJTLinstname:Universidad de Bogotá Jorge Tadeo LozanoPersonal Protective EquipmentN95Filtering Facepiece RespiratorDecontaminationPandemicCOVID-19Síndrome respiratorio agudo graveCOVID-19SARS-CoV-2CoronavirusMicrowave- and heat-based decontamination of n95 filtering facepiece respirators: A systematic reviewArtículohttp://purl.org/coar/resource_type/c_2df8fbb1Acceso restringidohttp://purl.org/coar/access_right/c_f1cfS, GertsmanA, AgarwalK, O’HearnR, WebsterA, TsampalierosN, BarrowmanM, SampsonL, SikoraE, StaykovR, NgJ, GibsonT, DinhK, AgyeiG, ChamberlainJD, McNallyORIGINALCaptura.PNGCaptura.PNGVer portadaimage/png117240https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12332/1/Captura.PNG6323334a02debf6f6c1310edfb549915MD51open accessMicrowave--and-Heat-Based-Decontamination-of-N95-Filter_2020_Journal-of-Hosp.pdfMicrowave--and-Heat-Based-Decontamination-of-N95-Filter_2020_Journal-of-Hosp.pdfArtículo reservadoapplication/pdf590918https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12332/3/Microwave--and-Heat-Based-Decontamination-of-N95-Filter_2020_Journal-of-Hosp.pdf3ac636347514cdea18f41710e8d8a86aMD53embargoed access|||2200-08-26LICENSElicense.txtlicense.txttext/plain; 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