A hypothesis about the role of fetal hemoglobin in COVID-19

COVID-19 infection is less common in children (with higher fetal hemoglobin levels). In our preliminary study, we also observed a low prevalence and fatality of COVID-19 in countries with high rate of hemoglobinopathy carries. Given these two facts, the hemoglobin structure can play a role in the ph...

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Autores:
Tipo de recurso:
Article of investigation
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12143
Acceso en línea:
https://doi.org/10.1016/j.mehy.2020.109994
http://hdl.handle.net/20.500.12010/12143
Palabra clave:
COVID-19
Fetal hemoglobin
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
Rights
License
Acceso restringido
id UTADEO2_07ab818efc22da5b3661d9398197542d
oai_identifier_str oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12143
network_acronym_str UTADEO2
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dc.title.spa.fl_str_mv A hypothesis about the role of fetal hemoglobin in COVID-19
title A hypothesis about the role of fetal hemoglobin in COVID-19
spellingShingle A hypothesis about the role of fetal hemoglobin in COVID-19
COVID-19
Fetal hemoglobin
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
title_short A hypothesis about the role of fetal hemoglobin in COVID-19
title_full A hypothesis about the role of fetal hemoglobin in COVID-19
title_fullStr A hypothesis about the role of fetal hemoglobin in COVID-19
title_full_unstemmed A hypothesis about the role of fetal hemoglobin in COVID-19
title_sort A hypothesis about the role of fetal hemoglobin in COVID-19
dc.subject.spa.fl_str_mv COVID-19
Fetal hemoglobin
topic COVID-19
Fetal hemoglobin
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
dc.subject.lemb.spa.fl_str_mv Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
description COVID-19 infection is less common in children (with higher fetal hemoglobin levels). In our preliminary study, we also observed a low prevalence and fatality of COVID-19 in countries with high rate of hemoglobinopathy carries. Given these two facts, the hemoglobin structure can play a role in the physiopathology of COVID19 disease. Several drugs are known to increase fetal hemoglobin in adults. Adding these drugs to COVID-19 clinical trials may improve the patients’ outcomes.
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-08-24T15:26:23Z
dc.date.available.none.fl_str_mv 2020-08-24T15:26:23Z
dc.date.created.none.fl_str_mv 2020
dc.type.local.spa.fl_str_mv Artículo
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
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dc.identifier.issn.spa.fl_str_mv 0306-9877
dc.identifier.other.spa.fl_str_mv https://doi.org/10.1016/j.mehy.2020.109994
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12010/12143
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1016/j.mehy.2020.109994
identifier_str_mv 0306-9877
url https://doi.org/10.1016/j.mehy.2020.109994
http://hdl.handle.net/20.500.12010/12143
dc.language.iso.spa.fl_str_mv eng
language eng
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_f1cf
dc.rights.local.spa.fl_str_mv Acceso restringido
rights_invalid_str_mv Acceso restringido
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dc.format.extent.spa.fl_str_mv 4 páginas
dc.format.mimetype.spa.fl_str_mv image/jepg
dc.publisher.spa.fl_str_mv Medical Hypotheses
dc.source.spa.fl_str_mv reponame:Expeditio Repositorio Institucional UJTL
instname:Universidad de Bogotá Jorge Tadeo Lozano
instname_str Universidad de Bogotá Jorge Tadeo Lozano
institution Universidad de Bogotá Jorge Tadeo Lozano
reponame_str Expeditio Repositorio Institucional UJTL
collection Expeditio Repositorio Institucional UJTL
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spelling 2020-08-24T15:26:23Z2020-08-24T15:26:23Z20200306-9877https://doi.org/10.1016/j.mehy.2020.109994http://hdl.handle.net/20.500.12010/12143https://doi.org/10.1016/j.mehy.2020.109994COVID-19 infection is less common in children (with higher fetal hemoglobin levels). In our preliminary study, we also observed a low prevalence and fatality of COVID-19 in countries with high rate of hemoglobinopathy carries. Given these two facts, the hemoglobin structure can play a role in the physiopathology of COVID19 disease. Several drugs are known to increase fetal hemoglobin in adults. Adding these drugs to COVID-19 clinical trials may improve the patients’ outcomes.4 páginasimage/jepgengMedical Hypothesesreponame:Expeditio Repositorio Institucional UJTLinstname:Universidad de Bogotá Jorge Tadeo LozanoCOVID-19Fetal hemoglobinSíndrome respiratorio agudo graveCOVID-19SARS-CoV-2CoronavirusA hypothesis about the role of fetal hemoglobin in COVID-19Artículohttp://purl.org/coar/resource_type/c_2df8fbb1Acceso restringidohttp://purl.org/coar/access_right/c_f1cfSotoudeh, EhsanSotoudeh, HoumanORIGINALCaptura.PNGCaptura.PNGVer portadaimage/png178902https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12143/1/Captura.PNG3aac4df2307317a188b956f821243607MD51open accessA-hypothesis-about-the-role-of-fetal-hemoglobin-in-COV_2020_Medical-Hypothes.pdfA-hypothesis-about-the-role-of-fetal-hemoglobin-in-COV_2020_Medical-Hypothes.pdfArtículo reservadoapplication/pdf913273https://expeditiorepositorio.utadeo.edu.co/bitstream/20.500.12010/12143/3/A-hypothesis-about-the-role-of-fetal-hemoglobin-in-COV_2020_Medical-Hypothes.pdfd2f577ea79a4c29caf376c4c01c1b964MD53embargoed access|||2200-08-24LICENSElicense.txtlicense.txttext/plain; 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