Probing infectious disease by single-cell RNA sequencing: progresses and perspectives

The increasing application of single-cell RNA sequencing (scRNA-seq) technology in life science and biomedical research has significantly increased our understanding of the cellular heterogeneities in immunology, oncology and developmental biology. This review will summarize the development of vario...

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Autores:
Tipo de recurso:
Article of investigation
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/15305
Acceso en línea:
https://doi.org/10.1016/j.csbj.2020.10.016
http://hdl.handle.net/20.500.12010/15305
Palabra clave:
Single-cell RNA sequencing
Infectious diseases
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
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License
Abierto (Texto Completo)
Description
Summary:The increasing application of single-cell RNA sequencing (scRNA-seq) technology in life science and biomedical research has significantly increased our understanding of the cellular heterogeneities in immunology, oncology and developmental biology. This review will summarize the development of various scRNA-seq technologies; primarily discussing the application of scRNA-seq on infectious diseases, and exploring the current development, challenges, and potential applications of scRNA-seq technology in the future.