Diagnóstico y caracterización de cáncer mamario en seres humanos: Una revisión

El cáncer de mama es una enfermedad de tipo clonal ya sea por mutación adquirida o por mutación de línea germinal que introduce una transformación significativa en la estructura anatómica del parénquima mamario o en los elementos que le sirven de soporte. En diversos países, las alarmantes estadísti...

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Autores:
Sandra Vargas, Sandra
Vera, Miguel
Tipo de recurso:
Fecha de publicación:
2021
Institución:
Universidad Simón Bolívar
Repositorio:
Repositorio Digital USB
Idioma:
spa
OAI Identifier:
oai:bonga.unisimon.edu.co:20.500.12442/9697
Acceso en línea:
https://hdl.handle.net/20.500.12442/9697
http://doi.org/10.5281/zenodo.5228817
Palabra clave:
Cáncer mamario
imagenología médica
Operadores inteligentes
Breast cancer
Medical imaging
Artificial intelligence operators
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openAccess
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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
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dc.title.spa.fl_str_mv Diagnóstico y caracterización de cáncer mamario en seres humanos: Una revisión
dc.title.translated.eng.fl_str_mv Diagnosis and characterization of breast cancer in humans: A review
title Diagnóstico y caracterización de cáncer mamario en seres humanos: Una revisión
spellingShingle Diagnóstico y caracterización de cáncer mamario en seres humanos: Una revisión
Cáncer mamario
imagenología médica
Operadores inteligentes
Breast cancer
Medical imaging
Artificial intelligence operators
title_short Diagnóstico y caracterización de cáncer mamario en seres humanos: Una revisión
title_full Diagnóstico y caracterización de cáncer mamario en seres humanos: Una revisión
title_fullStr Diagnóstico y caracterización de cáncer mamario en seres humanos: Una revisión
title_full_unstemmed Diagnóstico y caracterización de cáncer mamario en seres humanos: Una revisión
title_sort Diagnóstico y caracterización de cáncer mamario en seres humanos: Una revisión
dc.creator.fl_str_mv Sandra Vargas, Sandra
Vera, Miguel
dc.contributor.author.none.fl_str_mv Sandra Vargas, Sandra
Vera, Miguel
dc.subject.spa.fl_str_mv Cáncer mamario
imagenología médica
Operadores inteligentes
topic Cáncer mamario
imagenología médica
Operadores inteligentes
Breast cancer
Medical imaging
Artificial intelligence operators
dc.subject.eng.fl_str_mv Breast cancer
Medical imaging
Artificial intelligence operators
description El cáncer de mama es una enfermedad de tipo clonal ya sea por mutación adquirida o por mutación de línea germinal que introduce una transformación significativa en la estructura anatómica del parénquima mamario o en los elementos que le sirven de soporte. En diversos países, las alarmantes estadísticas asociadas con la muerte por este tipo de cáncer justifican el enorme esfuerzo que está haciendo la comunidad internacional para abordar este problema de salud. Mediante el presente trabajo, para construir el estado del arte actual del cáncer mamario, se realizó una revisión sistemática de diversas fuentes de información que incluyó un total de ochenta y cinco documentos o unidades de análisis. Los hallazgos fundamentales muestran que, históricamente, se ha producido una constante evolución en el desarrollo y perfeccionamiento tanto de la terapéutica como de las técnicas de detección del cáncer mamario, lo cual ha estado respaldado por la incorporación de los avances tecnológicos en la rutina clínica y en la cultura de los sujetos aquejados por esta patología. En ese sentido, el análisis de los mencionados documentos permitió detectar una importante transformación de los protocolos de diagnóstico y seguimiento de este tipo de cáncer, una profusa aplicación de las técnicas imagenológicas médicas y un visible posicionamiento de las técnicas de aprendizaje automático, especialmente de los operadores de inteligencia artificial, como elementos fundamentales para el desarrollo de un sinnúmero de estrategias bioingenieriles las cuales pueden ser muy útiles como apoyo clínico para los especialistas oncólogos que estudian el cáncer mamario.
publishDate 2021
dc.date.issued.none.fl_str_mv 2021
dc.date.accessioned.none.fl_str_mv 2022-05-13T18:59:34Z
dc.date.available.none.fl_str_mv 2022-05-13T18:59:34Z
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http://doi.org/10.5281/zenodo.5228817
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dc.publisher.spa.fl_str_mv Universidad Central de Venezuela
dc.source.spa.fl_str_mv AVFT - Archivos Venezolanos de Farmacología y Terapéutica
dc.source.none.fl_str_mv Vol. 40, No. 4 (2021)
institution Universidad Simón Bolívar
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spelling Sandra Vargas, Sandra12c90a24-d450-41a5-8415-76bf6944e9e6Vera, Miguelc485e4e3-5bbd-4d00-8ec7-e5bc8a0a21e32022-05-13T18:59:34Z2022-05-13T18:59:34Z202126107988https://hdl.handle.net/20.500.12442/9697http://doi.org/10.5281/zenodo.5228817El cáncer de mama es una enfermedad de tipo clonal ya sea por mutación adquirida o por mutación de línea germinal que introduce una transformación significativa en la estructura anatómica del parénquima mamario o en los elementos que le sirven de soporte. En diversos países, las alarmantes estadísticas asociadas con la muerte por este tipo de cáncer justifican el enorme esfuerzo que está haciendo la comunidad internacional para abordar este problema de salud. Mediante el presente trabajo, para construir el estado del arte actual del cáncer mamario, se realizó una revisión sistemática de diversas fuentes de información que incluyó un total de ochenta y cinco documentos o unidades de análisis. Los hallazgos fundamentales muestran que, históricamente, se ha producido una constante evolución en el desarrollo y perfeccionamiento tanto de la terapéutica como de las técnicas de detección del cáncer mamario, lo cual ha estado respaldado por la incorporación de los avances tecnológicos en la rutina clínica y en la cultura de los sujetos aquejados por esta patología. En ese sentido, el análisis de los mencionados documentos permitió detectar una importante transformación de los protocolos de diagnóstico y seguimiento de este tipo de cáncer, una profusa aplicación de las técnicas imagenológicas médicas y un visible posicionamiento de las técnicas de aprendizaje automático, especialmente de los operadores de inteligencia artificial, como elementos fundamentales para el desarrollo de un sinnúmero de estrategias bioingenieriles las cuales pueden ser muy útiles como apoyo clínico para los especialistas oncólogos que estudian el cáncer mamario.Breast cancer is a clonal type of disease either by acquired mutation or by germ line that introduces a significant transformation in the anatomical structure of the breast parenchyma or in the elements that support it. In several countries, the alarming statistics associated with death from this type of cancer justify the enormous effort being made by the international community to address this health problem. To build the current state of the art of breast cancer, through the present work, a systematic review of diverse sources of information was carried out, which included a total of eighty-five documents or analysis units. The fundamental findings show that, historically, there has been a constant evolution in the development and improvement of both the therapeutics and the techniques of breast cancer detection, which has been supported by the incorporation of technological advances in the clinical routine and in the culture of the subjects affected by this pathology. In that sense, the analysis of the mentioned documents allowed detecting an important transformation of the protocols of diagnosis and monitoring of this type of cancer, a profuse application of the medical imaging techniques and a visible positioning of the automatic learning techniques, especially of the artificial intelligence operators, as fundamental elements for the development of an endless number of bioengineering strategies which can be very useful as clinical support for the oncology specialists who study breast cancer.pdfspaUniversidad Central de VenezuelaAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2AVFT - Archivos Venezolanos de Farmacología y TerapéuticaVol. 40, No. 4 (2021)Cáncer mamarioimagenología médicaOperadores inteligentesBreast cancerMedical imagingArtificial intelligence operatorsDiagnóstico y caracterización de cáncer mamario en seres humanos: Una revisiónDiagnosis and characterization of breast cancer in humans: A reviewinfo:eu-repo/semantics/articleArtículo científicohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_2df8fbb1Organización Mundial de la Salud (OMS): Enfermedades no trans- misibles: perfiles de países 2018. https://www.who.int/nmh/coun- tries/es/Bardia A, Hurvitz S. Targeted therapy for premenopausal women with HR+, HER2− advanced breast cancer: focus on special consid- erations and latest advances. Clin Cancer Res 2018;24:5206-5218Sociedad americana de oncología clínica 2020 https://www.asco. orgDan L. Longo, Dennis L. Kasper, J. Larry Jameson, Anthony S. Fauci, Stephen L. Hauser, Joseph Loscalzo Harrison. Principios de Medicina Interna, 18e McGrawHill 2012Organización Panamericana de la Salud (OPS) Perfiles de país so- bre cáncer 2020 https://www.paho.org/hq/index.php?option=com_ content&view=article&id=15716:country-cancer-profiles- 2020&Itemid=72576&lang=esMacMahon, B., Cole, P. and Brown, J. (1973). Etiology of Human Breast Cancer: A Review. JNCI: Journal of the National Cancer In- stitute. 50, 21-42.1973Hashemi, S., Rafiemanesh, H., Aghamohammadi, T et al. Preva- lence of anxiety among breast cancer patients: a systematic review and meta-analysis. Breast Cancer. 27, 166-178. 2020. https://doi. org/10.1007/s12282-019-01031-9Suzuki, H., Seki, A., Hosaka, T., Matsumoto, N., Tomita, M., Taka- hashi, M., and Yamauchi, H. Effects of a structured group interven- tion on obesity among breast cancer survivors. Breast Cancer. 27, 236-242. 2020. https://doi.org/10.1007/s12282-019-01013-xNishiyama, K., Taira, N., Mizoo, T., Kochi, M et al. Infuence of breast density on breast cancer risk: a case control study in Japanese women. Breast Cancer. 27, 277-283. 2020. https://doi.org/10.1007/ s12282-019-01018-6Nakagawa, A., Fujimoto, H., Nagashima, T et al. Histological fea- tures of skin and subcutaneous tissue in patients with breast cancer who have received neoadjuvant chemotherapy and their relation- ship to post-treatment edema. Breast Cancer. 27, 77-84. 2020. https://doi.org/10.1007/s12282-019-00996-xNaito, Y., Kai, Y., Ishikawa, T et al. Chemotherapy-induced nausea and vomiting in patients with breast cancer: a prospective cohort study. Breast Cancer. 27, 122-128. 2020. https://doi.org/10.1007/ s12282-019-01001-1.Izumori, A., Kokubu, Y., Sato, K et al. Usefulness of second-look ultrasonography using anatomical breast structures as indicators for magnetic resonance imaging-detected breast abnormalities. Breast Cancer. 27,129-139.2020. https://doi.org/10.1007/s12282- 019-01003-zPereira, H., Pinder, S.E., Sibbering, D et al. Pathological prognosticfactors in breast cancer. IV: Should you be a typer or a grader? A comparative study of two histological prognostic features in oper- able breast carcinoma. Histopathology. 27, 219-226. 1995. https:// doi.org/10.1111/j.1365-2559.1995.tb00213.xAswathy, M.A., Jagannath, M. Detection of breast cancer on digi- tal histopathology images: Present status and future possibili- ties. Informatics in Medicine Unlocked. 8, 74-79. 2017. https://doi. org/10.1016/j.imu.2016.11.001Yu, C., Chen, H., Li, Y et al. Breast cancer classification in patho- logical images based on hybrid features. 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