Molecular Mechanisms of Diabetic Kidney Disease
The inflammatory component of diabetic kidney disease has become of great interest in recent years, with genetic and epigenetic variants playing a fundamental role in the initiation and progression of the disease. Cells of the innate immune system play a major role in the pathogenesis of diabetic ki...
- Autores:
-
Rico-Fontalvo, Jorge
Aroca, Gustavo
Cabrales, José
Daza-Arnedo, Rodrigo
Yánez-Rodríguez, Tomas
Martínez-Ávila, María Cristina
Uparella-Gulfo, Isabella
Raad-Sarabia, María
- Tipo de recurso:
- Fecha de publicación:
- 2022
- Institución:
- Universidad Simón Bolívar
- Repositorio:
- Repositorio Digital USB
- Idioma:
- eng
- OAI Identifier:
- oai:bonga.unisimon.edu.co:20.500.12442/10501
- Acceso en línea:
- https://hdl.handle.net/20.500.12442/10501
https://doi.org/10.3390/ijms23158668
https://www.mdpi.com/1422-0067/23/15/8668
- Palabra clave:
- Genetics
Epigenetic
Inflammatory
Innate
Adaptive
Cytokines
Innovation
- Rights
- openAccess
- License
- Attribution-NonCommercial-NoDerivatives 4.0 Internacional
| Summary: | The inflammatory component of diabetic kidney disease has become of great interest in recent years, with genetic and epigenetic variants playing a fundamental role in the initiation and progression of the disease. Cells of the innate immune system play a major role in the pathogenesis of diabetic kidney disease, with a lesser contribution from the adaptive immune cells. Other components such as the complement system also play a role, as well as specific cytokines and chemokines. The inflammatory component of diabetic kidney disease is of great interest and is an active research field, with the hope to find potential innovative therapeutic targets. |
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