Characterization of patients with diabetic kidney disease nonalbuminuric phenotype. A single-center observational study

Introduction: The phenotypes with albuminuria and the nonalbuminuric phenotype in diabetic kidney disease (DKD) are known. The nonalbuminuric phenotype is defined with an estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m2 associated with km il.;p.albuminuria- creatinuria ratio (ACR)...

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Autores:
Salas Carmona, Yerina Hortensia
Serpa Diaz, Dagoberto
Salas Carmona, Yuris C
Ramos Clason, Enrique C
Raad Sarabia, María
Daza Arnedo, Rodrigo
Cardona Blanco, María Ximena
Parra Sánchez, Paula
Rico Fontalvo, Jorge
Tipo de recurso:
Fecha de publicación:
2024
Institución:
Universidad Simón Bolívar
Repositorio:
Repositorio Digital USB
Idioma:
eng
OAI Identifier:
oai:bonga.unisimon.edu.co:20.500.12442/14855
Acceso en línea:
https://hdl.handle.net/20.500.12442/14855
http://doi.org/10.56867/78
https://rev-sen.ec/index.php/revista/article/view/78
Palabra clave:
Chronic kidney disease
Diabetic kidney disease
Mellitus diabetes
Albuminuria
Creatinuria
Glomerular filtration rate
Rights
openAccess
License
Attribution-NonCommercial-NoDerivs 3.0 United States
Description
Summary:Introduction: The phenotypes with albuminuria and the nonalbuminuric phenotype in diabetic kidney disease (DKD) are known. The nonalbuminuric phenotype is defined with an estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m2 associated with km il.;p.albuminuria- creatinuria ratio (ACR) less than 30 mg/gr. The objective of the present study was to describe the clinical characteristics of patients with DKD nonalbuminuric phenotype (nADKD). Methods: This is an observational, descriptive study of patients treated at an IPS in Cartagena, Colombia, from 2021 to 2022. Results: Of a total of 7698 patients with DKD criteria, 1714 patients (22.3%) had nA-DKD criteria, with a median age of 69 years (IQR 62-76), and women (75.73%). A total of 85% had hypertension, (22.3%) dyslipidemia, and the average BMI was in the overweight range. 9.5% had a history of smoking. Little presence of diabetic retinopathy was found. Conclusion: Nonalbuminuric phenotype diabetic kidney disease is not uncommon in our environment. In general, the characteristics of our patients are very similar to those reported in other series.