Relation Between Levels of Leptine and Metabolic Parameters in Children and Adolescents

Objective: To determine the relationship between leptin levels and metabolic parameters in children and adolescents. Methods: Descriptive cross-sectional study. Laboratory biochemical values and anthropometric parameters were determined. Univariate analysis was performed with measurements of frequen...

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Autores:
Pérez-Álvarez, Omar
Navarro-Lechuga, Edgar
Garavito-Galofre, María del Pilar
Navarro-Jiménez, Eduardo
Tipo de recurso:
Fecha de publicación:
2018
Institución:
Universidad Simón Bolívar
Repositorio:
Repositorio Digital USB
Idioma:
eng
OAI Identifier:
oai:bonga.unisimon.edu.co:20.500.12442/2321
Acceso en línea:
http://hdl.handle.net/20.500.12442/2321
Palabra clave:
Pediatric obesity
Leptin
Glycemia
Adipose tissue
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License
Licencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional
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oai_identifier_str oai:bonga.unisimon.edu.co:20.500.12442/2321
network_acronym_str USIMONBOL2
network_name_str Repositorio Digital USB
repository_id_str
dc.title.eng.fl_str_mv Relation Between Levels of Leptine and Metabolic Parameters in Children and Adolescents
title Relation Between Levels of Leptine and Metabolic Parameters in Children and Adolescents
spellingShingle Relation Between Levels of Leptine and Metabolic Parameters in Children and Adolescents
Pediatric obesity
Leptin
Glycemia
Adipose tissue
title_short Relation Between Levels of Leptine and Metabolic Parameters in Children and Adolescents
title_full Relation Between Levels of Leptine and Metabolic Parameters in Children and Adolescents
title_fullStr Relation Between Levels of Leptine and Metabolic Parameters in Children and Adolescents
title_full_unstemmed Relation Between Levels of Leptine and Metabolic Parameters in Children and Adolescents
title_sort Relation Between Levels of Leptine and Metabolic Parameters in Children and Adolescents
dc.creator.fl_str_mv Pérez-Álvarez, Omar
Navarro-Lechuga, Edgar
Garavito-Galofre, María del Pilar
Navarro-Jiménez, Eduardo
dc.contributor.author.none.fl_str_mv Pérez-Álvarez, Omar
Navarro-Lechuga, Edgar
Garavito-Galofre, María del Pilar
Navarro-Jiménez, Eduardo
dc.subject.eng.fl_str_mv Pediatric obesity
Leptin
Glycemia
Adipose tissue
topic Pediatric obesity
Leptin
Glycemia
Adipose tissue
description Objective: To determine the relationship between leptin levels and metabolic parameters in children and adolescents. Methods: Descriptive cross-sectional study. Laboratory biochemical values and anthropometric parameters were determined. Univariate analysis was performed with measurements of frequencies and percentages and bivariate analysis through statistical significance tests (p <0.05). In case of multiple comparisons, the Bonferroni correction was made. Results: There were higher levels of leptin to higher adipose tissue, while in the metabolic parameters a relationship was observed between high levels of glycemia and leptin independent of the variables gender, age group and nutritional status. There was no clear relationship between high levels of leptin and those of the lipid profile. Conclusions: There was a relationship between leptin concentrations and nutritional status and in the relationship of leptin with the metabolic parameters studied, there was an association with glycemia, while this association was not clear with the lipid profile.
publishDate 2018
dc.date.accessioned.none.fl_str_mv 2018-10-26T16:14:37Z
dc.date.available.none.fl_str_mv 2018-10-26T16:14:37Z
dc.date.issued.none.fl_str_mv 2018
dc.type.eng.fl_str_mv article
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.identifier.issn.none.fl_str_mv 19169744
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12442/2321
identifier_str_mv 19169744
url http://hdl.handle.net/20.500.12442/2321
dc.language.iso.eng.fl_str_mv eng
language eng
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.license.spa.fl_str_mv Licencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional
rights_invalid_str_mv Licencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional
http://purl.org/coar/access_right/c_abf2
dc.publisher.spa.fl_str_mv Canadian Centrer of Science and Education
dc.source.eng.fl_str_mv Global Journal of Health Science
dc.source.spa.fl_str_mv Vol. 10, No. 11 (2018)
institution Universidad Simón Bolívar
dc.source.uri.eng.fl_str_mv http://www.ccsenet.org/journal/index.php/gjhs/article/view/0/37226
bitstream.url.fl_str_mv https://bonga.unisimon.edu.co/bitstreams/08fa8066-6d51-4eaf-9ef2-3db0a041174d/download
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spelling Licencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacionalhttp://purl.org/coar/access_right/c_abf2Pérez-Álvarez, Omara03dc0ec-6915-4390-abf4-edbe35b7ca13-1Navarro-Lechuga, Edgarb8a18f44-c3f6-4391-9b72-e75e2be3681e-1Garavito-Galofre, María del Pilara9db2fe7-d256-409d-b876-e340dc1c795b-1Navarro-Jiménez, Eduardo0fcefc20-f73a-43a6-9eab-6c9c668cabb9-12018-10-26T16:14:37Z2018-10-26T16:14:37Z201819169744http://hdl.handle.net/20.500.12442/2321Objective: To determine the relationship between leptin levels and metabolic parameters in children and adolescents. Methods: Descriptive cross-sectional study. Laboratory biochemical values and anthropometric parameters were determined. Univariate analysis was performed with measurements of frequencies and percentages and bivariate analysis through statistical significance tests (p <0.05). In case of multiple comparisons, the Bonferroni correction was made. Results: There were higher levels of leptin to higher adipose tissue, while in the metabolic parameters a relationship was observed between high levels of glycemia and leptin independent of the variables gender, age group and nutritional status. There was no clear relationship between high levels of leptin and those of the lipid profile. Conclusions: There was a relationship between leptin concentrations and nutritional status and in the relationship of leptin with the metabolic parameters studied, there was an association with glycemia, while this association was not clear with the lipid profile.engCanadian Centrer of Science and EducationGlobal Journal of Health ScienceVol. 10, No. 11 (2018)http://www.ccsenet.org/journal/index.php/gjhs/article/view/0/37226Pediatric obesityLeptinGlycemiaAdipose tissueRelation Between Levels of Leptine and Metabolic Parameters in Children and Adolescentsarticlehttp://purl.org/coar/resource_type/c_6501AL-Suhaimi, E. A. & Shehzad, A. (2013). 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Datos y cifras sobre obesidad infantil. Retrieved from http://www.who.int/end-childhood-obesity/facts/es/Skurk, T., Alberti-Huber, C., Herder, C. & Hauner, H. (2007). Relationship between Adipocyte Size and Adipokine Expression and Secretion. J. Clin. Endocrinol. Metab., 92, 1023-1033. https://doi.org/10.1210/jc.2006-1055Zhang, M., Cheng, H., Zhao, X., Hou, D., Yan, Y., Cianflone, K., ... & Mi, J. (2017). Leptin and leptin-to-adiponectin ratio predict adiposity gain in nonobese children over a six-year period. Childhood Obesity, 13(3), 213-221. https://doi.org/10.1089/chi.2016.0273Zhang, Y., Zitsman, J. L., Hou, J., Fennoy, I., Guo, K., Feinberg, J., & Leibel, R. L. (2014). Fat cell size and adipokine expression in relation to gender, depot, and metabolic risk factors in morbidly obese adolescents. Obesity, 22(3), 691-697. https://doi.org/10.1002/oby.20528Borda, M., Tuesca, R. & Navarro, E. (2011). Métodos cuantitativos Herramientas para la investigación en salud.Chaila, M. 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Pediatría Atención Primaria, 14, 9-14. https://doi.org/10.4321/S1139-76322012000200001LICENSElicense.txtlicense.txttext/plain; charset=utf-8368https://bonga.unisimon.edu.co/bitstreams/08fa8066-6d51-4eaf-9ef2-3db0a041174d/download3fdc7b41651299350522650338f5754dMD5220.500.12442/2321oai:bonga.unisimon.edu.co:20.500.12442/23212019-04-11 21:51:42.857metadata.onlyhttps://bonga.unisimon.edu.coDSpace UniSimonbibliotecas@biteca.comPGEgcmVsPSJsaWNlbnNlIiBocmVmPSJodHRwOi8vY3JlYXRpdmVjb21tb25zLm9yZy9saWNlbnNlcy9ieS1uYy80LjAvIj48aW1nIGFsdD0iTGljZW5jaWEgQ3JlYXRpdmUgQ29tbW9ucyIgc3R5bGU9ImJvcmRlci13aWR0aDowIiBzcmM9Imh0dHBzOi8vaS5jcmVhdGl2ZWNvbW1vbnMub3JnL2wvYnktbmMvNC4wLzg4eDMxLnBuZyIgLz48L2E+PGJyLz5Fc3RhIG9icmEgZXN0w6EgYmFqbyB1bmEgPGEgcmVsPSJsaWNlbnNlIiBocmVmPSJodHRwOi8vY3JlYXRpdmVjb21tb25zLm9yZy9saWNlbnNlcy9ieS1uYy80LjAvIj5MaWNlbmNpYSBDcmVhdGl2ZSBDb21tb25zIEF0cmlidWNpw7NuLU5vQ29tZXJjaWFsIDQuMCBJbnRlcm5hY2lvbmFsPC9hPi4=

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