DNA damage, salivary cortisol levels, and cognitive parameters in a nursing team

In a cross-sectional study of women in a nursing team at a university hospital in southern Brazil, we studied DNA damage, salivary cortisol levels, and cognition. DNA damage was measured in blood leukocytes with the comet assay and the micronucleus test. Salivary cortisol levels were determined upon...

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Autores:: Bortolotto, Iranez
Scherer de Brum, Ana Paula
Nikolova Guecheva, Temenouga
Milano de Souza, Larissa
Lia de Paula-Ramos, Ana Ligia
Trindade, Cristiano
Rosat Consiglio, Angelica

Tipo de recurso:

Fecha de publicación:: 2020

Institución:: Universidad Simón Bolívar

Repositorio:: Repositorio Digital USB

Idioma:: eng

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dc.title.eng.fl_str_mv	DNA damage, salivary cortisol levels, and cognitive parameters in a nursing team
title	DNA damage, salivary cortisol levels, and cognitive parameters in a nursing team
spellingShingle	DNA damage, salivary cortisol levels, and cognitive parameters in a nursing team Comet assay Cortisol Genotoxicity Micronucleus test Occupational health
title_short	DNA damage, salivary cortisol levels, and cognitive parameters in a nursing team
title_full	DNA damage, salivary cortisol levels, and cognitive parameters in a nursing team
title_fullStr	DNA damage, salivary cortisol levels, and cognitive parameters in a nursing team
title_full_unstemmed	DNA damage, salivary cortisol levels, and cognitive parameters in a nursing team
title_sort	DNA damage, salivary cortisol levels, and cognitive parameters in a nursing team
dc.creator.fl_str_mv	Bortolotto, Iranez Scherer de Brum, Ana Paula Nikolova Guecheva, Temenouga Milano de Souza, Larissa Lia de Paula-Ramos, Ana Ligia Trindade, Cristiano Rosat Consiglio, Angelica
dc.contributor.author.none.fl_str_mv	Bortolotto, Iranez Scherer de Brum, Ana Paula Nikolova Guecheva, Temenouga Milano de Souza, Larissa Lia de Paula-Ramos, Ana Ligia Trindade, Cristiano Rosat Consiglio, Angelica
dc.subject.eng.fl_str_mv	Comet assay Cortisol Genotoxicity Micronucleus test Occupational health
topic	Comet assay Cortisol Genotoxicity Micronucleus test Occupational health
description	In a cross-sectional study of women in a nursing team at a university hospital in southern Brazil, we studied DNA damage, salivary cortisol levels, and cognition. DNA damage was measured in blood leukocytes with the comet assay and the micronucleus test. Salivary cortisol levels were determined upon waking, 30 min later, and at bedtime. Cognition was evaluated according to the Stroop, Digit span and Word span tests. Cortisol levels on waking up were associated negatively with the number of years the employee worked at the institution and positively with the DNA damage in comet assay. Cognitive scores were lower when the cortisol levels were low at awakening and high at bedtime; and were associated positively with educational level. Cortisol status may influence overall health as well as essential work skills, such as attention.
publishDate	2020
dc.date.accessioned.none.fl_str_mv	2020-12-09T14:26:25Z
dc.date.available.none.fl_str_mv	2020-12-09T14:26:25Z
dc.date.issued.none.fl_str_mv	2020
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dc.identifier.uri.none.fl_str_mv	https://hdl.handle.net/20.500.12442/6855
dc.identifier.doi.none.fl_str_mv	https://doi.org/10.1016/j.mrgentox.2020.503300
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dc.publisher.eng.fl_str_mv	Elsevier
dc.source.eng.fl_str_mv	Mutation Research/Genetic Toxicology and Environmental Mutagenesis
dc.source.none.fl_str_mv	Vol. 861-862 (2021)
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spelling	Bortolotto, Iranezc0fae8b2-ac0f-47c8-8966-2209844eefccScherer de Brum, Ana Paula8fd55bea-87e2-43a4-8705-859affcede1cNikolova Guecheva, Temenougac71a540e-9ac4-420e-b274-2f97832481f8Milano de Souza, Larissac19b6332-26b4-4c73-88f7-6a42eace9892Lia de Paula-Ramos, Ana Ligiafbf4521b-06e8-41c9-8d31-312fc24c6256Trindade, Cristiano30b50065-9290-4b8a-837b-01634d3219d7Rosat Consiglio, Angelicad3da889e-6842-4a91-92a1-34475b1916ae2020-12-09T14:26:25Z2020-12-09T14:26:25Z202013835718https://hdl.handle.net/20.500.12442/6855https://doi.org/10.1016/j.mrgentox.2020.503300https://www.sciencedirect.com/science/article/pii/S1383571820301716?dgcid=authorIn a cross-sectional study of women in a nursing team at a university hospital in southern Brazil, we studied DNA damage, salivary cortisol levels, and cognition. DNA damage was measured in blood leukocytes with the comet assay and the micronucleus test. Salivary cortisol levels were determined upon waking, 30 min later, and at bedtime. Cognition was evaluated according to the Stroop, Digit span and Word span tests. Cortisol levels on waking up were associated negatively with the number of years the employee worked at the institution and positively with the DNA damage in comet assay. Cognitive scores were lower when the cortisol levels were low at awakening and high at bedtime; and were associated positively with educational level. Cortisol status may influence overall health as well as essential work skills, such as attention.pdfengElsevierAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Mutation Research/Genetic Toxicology and Environmental MutagenesisVol. 861-862 (2021)Comet assayCortisolGenotoxicityMicronucleus testOccupational healthDNA damage, salivary cortisol levels, and cognitive parameters in a nursing teaminfo:eu-repo/semantics/articleArtículo científicohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_2df8fbb1Workplace Stress: a Collective Challenge, International Labour Organization (ILO), 2016. www.ilo.org/safedayD.T. Costa, M. do C.F. Martins, Estresse em profissionais de enfermagem: impacto do conflito no grupo e do poder do m´edico/ Stress in nursing professionals: impact of conflict in the group and the power of the doctor, Rev. Esc. Enferm. USP. 45 (2011) 1191–1198, https://doi.org/10.1590/S0080-62342011000500023.R.M.G.S. Coutrin, P.R. Freua, C.M. Guimaraes, ˜ Estresse em enfermagem: uma analise ´ do conhecimento produzido na litertura brasileira no período de 1982 a 2001/ Nursing stress: an analysis of knowledge production in brazilian literature Bases, Bireme.Br. 12 (4) (2003) 486–494.S.M. de, C. Farias, O.Lde C. Teixeira, W. Moreira, M.A.F. de Oliveira, M.O. Pereira, Caracterizaçao ˜ dos sintomas físicos de estresse na equipe de pronto atendimento/ Characterization of physical symptoms of stress in the emergency care team, Rev. Esc. Enferm. USP. 45 (2011) 722–729, https://doi.org/10.1590/S0080- 62342011000300025M.M. Theme Filha, M.Ade S. Costa, M.C.R. Guilam, M.M. Theme Filha, M.Ade S. Costa, M.C.R. Guilam, Occupational stress and self-rated health among nurses, Rev. Lat. Enfermagem 21 (2013) 475–483, https://doi.org/10.1590/S0104- 11692013000200002.Rda S. Hanzelmann, J.P. Passos, Imagens e representaçoes ˜ da enfermagem acerca do stress e sua influˆencia na atividade laboral/ Nursing images and representations about stress and its influence on work activity, Rev. Esc. Enferm. USP. 44 (2010) 694–701, https://doi.org/10.1590/S0080-62342010000300020.V.A. Mininel, P.C.P. Baptista, V.E.A. Felli, Cargas psíquicas e processos de desgaste em trabalhadores de enfermagem de hospitais universitarios ´ brasileiros/ Psychic loads and wear processes in nursing workers at Brazilian university hospitals, Rev. Lat. Am. Enfermagem. 19 (2011) 340–347, https://doi.org/10.1590/S0104- 11692011000200016B. Paschoalini, M.M. Oliveira, M.C. Frigério, A.L.R.P. Dias, F.H. dos Santos, Cognitive and emotional effects of occupational stress in nursing professionals, Acta Paul. Enferm. 21 (2008) 487–492, https://doi.org/10.1590/S0103- 21002008000300017.T.L. Simons, R.S. Peterson, Task conflict and relationship conflict in top management teams: the pivotal role of intragroup trust, J. 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Psychol. 70 (2019) 703–718, https://doi.org/10.1146/annurev-psych-010418-102936.LICENSElicense.txtlicense.txttext/plain; charset=utf-8381https://bonga.unisimon.edu.co/bitstreams/dea4646a-08ce-4cba-bebe-dbaad86ecdc1/download733bec43a0bf5ade4d97db708e29b185MD53ORIGINALPDF.pdfPDF.pdfPDFapplication/pdf1218789https://bonga.unisimon.edu.co/bitstreams/0fd3705d-b9e8-4f7b-b72f-3493f9de0ee6/download82ffe3f83e060791b04bc613beeb7880MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805https://bonga.unisimon.edu.co/bitstreams/8a2d2c8e-f734-4d30-9d17-4aaf37ecbff3/download4460e5956bc1d1639be9ae6146a50347MD52TEXTDNA damage, salivary cortisol levels, and cognitive parameters in a nursing team.PDF.txtDNA damage, salivary cortisol levels, and cognitive parameters in a nursing team.PDF.txtExtracted texttext/plain67373https://bonga.unisimon.edu.co/bitstreams/ae83269d-dcc6-4551-a08c-4489ee3f7e95/download80b3f88bdc7e4b46d0c258a346989f8cMD54PDF.pdf.txtPDF.pdf.txtExtracted texttext/plain74700https://bonga.unisimon.edu.co/bitstreams/08c80daa-5d19-4474-9f28-fc416284c2b1/download3130fbae88106836164eafed23fa979dMD56THUMBNAILDNA damage, salivary cortisol levels, and cognitive parameters in a nursing team.PDF.jpgDNA damage, salivary cortisol levels, and cognitive parameters in a nursing team.PDF.jpgGenerated Thumbnailimage/jpeg1717https://bonga.unisimon.edu.co/bitstreams/dc78bb64-de39-4b86-8199-35ac29a5d0d7/downloade67e9175ca30575e5b3c0fba92755137MD55PDF.pdf.jpgPDF.pdf.jpgGenerated Thumbnailimage/jpeg5846https://bonga.unisimon.edu.co/bitstreams/07ca6adc-04d1-4bb1-9c51-4e47c0dfd6e9/downloadcead8444bec9245be0900d7bcd99e029MD5720.500.12442/6855oai:bonga.unisimon.edu.co:20.500.12442/68552024-08-14 21:52:13.325http://creativecommons.org/licenses/by-nc-nd/4.0/Attribution-NonCommercial-NoDerivatives 4.0 Internacionalopen.accesshttps://bonga.unisimon.edu.coRepositorio Digital Universidad Simón Bolívarrepositorio.digital@unisimon.edu.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

DNA damage, salivary cortisol levels, and cognitive parameters in a nursing team

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