Cell Signaling in Neuronal Stem Cells

The defining characteristic of neural stem cells (NSCs) is their ability to multiply through symmetric divisions and proliferation, and differentiation by asymmetric divisions, thus giving rise to different types of cells of the central nervous system (CNS). A strict temporal space control of the NS...

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Autores:
Navarro Quiroz, Elkin
Navarro Quiroz, Roberto
Ahmad, Mostapha
Gomez Escorcia, Lorena
Villarreal, Jose Luis
Fernandez Ponce, Cecilia
Aroca Martinez, Gustavo
Tipo de recurso:
Fecha de publicación:
2018
Institución:
Universidad Simón Bolívar
Repositorio:
Repositorio Digital USB
Idioma:
eng
OAI Identifier:
oai:bonga.unisimon.edu.co:20.500.12442/2181
Acceso en línea:
http://hdl.handle.net/20.500.12442/2181
Palabra clave:
Neural stem cell
Wnt/beta-Catenin
Differentiation
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Licencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional
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dc.title.eng.fl_str_mv Cell Signaling in Neuronal Stem Cells
title Cell Signaling in Neuronal Stem Cells
spellingShingle Cell Signaling in Neuronal Stem Cells
Neural stem cell
Wnt/beta-Catenin
Differentiation
title_short Cell Signaling in Neuronal Stem Cells
title_full Cell Signaling in Neuronal Stem Cells
title_fullStr Cell Signaling in Neuronal Stem Cells
title_full_unstemmed Cell Signaling in Neuronal Stem Cells
title_sort Cell Signaling in Neuronal Stem Cells
dc.creator.fl_str_mv Navarro Quiroz, Elkin
Navarro Quiroz, Roberto
Ahmad, Mostapha
Gomez Escorcia, Lorena
Villarreal, Jose Luis
Fernandez Ponce, Cecilia
Aroca Martinez, Gustavo
dc.contributor.author.none.fl_str_mv Navarro Quiroz, Elkin
Navarro Quiroz, Roberto
Ahmad, Mostapha
Gomez Escorcia, Lorena
Villarreal, Jose Luis
Fernandez Ponce, Cecilia
Aroca Martinez, Gustavo
dc.subject.eng.fl_str_mv Neural stem cell
Wnt/beta-Catenin
Differentiation
topic Neural stem cell
Wnt/beta-Catenin
Differentiation
description The defining characteristic of neural stem cells (NSCs) is their ability to multiply through symmetric divisions and proliferation, and differentiation by asymmetric divisions, thus giving rise to different types of cells of the central nervous system (CNS). A strict temporal space control of the NSC differentiation is necessary, because its alterations are associated with neurological dysfunctions and, in some cases, death. This work reviews the current state of the molecular mechanisms that regulate the transcription in NSCs, organized according to whether the origin of the stimulus that triggers the molecular cascade in the CNS is internal (intrinsic factors) or whether it is the result of the microenvironment that surrounds the CNS (extrinsic factors).
publishDate 2018
dc.date.accessioned.none.fl_str_mv 2018-07-17T15:48:18Z
dc.date.available.none.fl_str_mv 2018-07-17T15:48:18Z
dc.date.issued.none.fl_str_mv 2018-07
dc.type.eng.fl_str_mv article
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.identifier.issn.none.fl_str_mv 20734409
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12442/2181
identifier_str_mv 20734409
url http://hdl.handle.net/20.500.12442/2181
dc.language.iso.eng.fl_str_mv eng
language eng
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.license.spa.fl_str_mv Licencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional
rights_invalid_str_mv Licencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional
http://purl.org/coar/access_right/c_abf2
dc.publisher.spa.fl_str_mv MDPI
dc.source.eng.fl_str_mv Revista Cells
dc.source.spa.fl_str_mv Vol. 7, No.7 (2018)
institution Universidad Simón Bolívar
dc.source.uri.eng.fl_str_mv http://www.mdpi.com/2073-4409/7/7/75/pdf
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spelling Licencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacionalhttp://purl.org/coar/access_right/c_abf2Navarro Quiroz, Elkin1ab744b9-f91d-4752-92b3-2a63d6263957-1Navarro Quiroz, Roberto42251988-da73-4d4c-a4f2-981e88bccdab-1Ahmad, Mostaphae2a2bc14-8863-46f5-a6fc-6020fca57918-1Gomez Escorcia, Lorena0eda4380-18c9-49b2-b09c-a02809a7d505-1Villarreal, Jose Luis83c6179f-410b-4eac-bb18-39c9a0c2feac-1Fernandez Ponce, Cecilia84dcbd1c-f973-44f4-9f41-e8a9057e69c6-1Aroca Martinez, Gustavo017ff8e4-9657-4ba7-b850-964bedb0c873-12018-07-17T15:48:18Z2018-07-17T15:48:18Z2018-0720734409http://hdl.handle.net/20.500.12442/2181The defining characteristic of neural stem cells (NSCs) is their ability to multiply through symmetric divisions and proliferation, and differentiation by asymmetric divisions, thus giving rise to different types of cells of the central nervous system (CNS). A strict temporal space control of the NSC differentiation is necessary, because its alterations are associated with neurological dysfunctions and, in some cases, death. This work reviews the current state of the molecular mechanisms that regulate the transcription in NSCs, organized according to whether the origin of the stimulus that triggers the molecular cascade in the CNS is internal (intrinsic factors) or whether it is the result of the microenvironment that surrounds the CNS (extrinsic factors).engMDPIRevista CellsVol. 7, No.7 (2018)http://www.mdpi.com/2073-4409/7/7/75/pdfNeural stem cellWnt/beta-CateninDifferentiationCell Signaling in Neuronal Stem Cellsarticlehttp://purl.org/coar/resource_type/c_6501Rosow, K.; Holzapfel, A.; Karlawish, J.H.; Baumgart, M.; Bain, L.J.; Khachaturian, A.S. Countrywide strategic plans on Alzheimer’s disease: Developing the framework for the international battle against Alzheimer’s disease. 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Eur. J. 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