Stevia rebaudiana Bertoni and Its Effects in Human Disease: Emphasizing Its Role in Inflammation, Atherosclerosis and Metabolic Syndrome
Purpose of Review. Stevia rebaudiana Bertoni is a perennial shrub with zero calorie content that has been increasing in popularity for its potential use as an adjuvant in the treatment of obesity. The level of evidence supporting general benefits to human health is insufficient. We conducted a revie...
- Autores:
-
Rojas, Edward
Bermúdez, Valmore
Fidilio, Enzamaria
Faria, Judith
Rojas, Joselyn
Cabrera de Bravo, Mayela
Contreras, Julio
Mantilla, Linda Pamela
Angarita, Lissé
Sepúlveda, Paola Amar
Kuzmar, Isaac
Motlaghzadeh, Yasaman
Mathew, Justin
- Tipo de recurso:
- Fecha de publicación:
- 2018
- Institución:
- Universidad Simón Bolívar
- Repositorio:
- Repositorio Digital USB
- Idioma:
- eng
- OAI Identifier:
- oai:bonga.unisimon.edu.co:20.500.12442/3585
- Acceso en línea:
- https://hdl.handle.net/20.500.12442/3585
- Palabra clave:
- Stevia rebaudiana Bertoni
Obesity
Type 2 diabetes
Hypertension
- Rights
- License
- Attribution-NonCommercial-NoDerivatives 4.0 Internacional
| Summary: | Purpose of Review. Stevia rebaudiana Bertoni is a perennial shrub with zero calorie content that has been increasing in popularity for its potential use as an adjuvant in the treatment of obesity. The level of evidence supporting general benefits to human health is insufficient. We conducted a review of the literature summarizing the current knowledge and role in human disease. Recent Findings. Despite stevia’s minimal systemic absorption, studies have been promising regarding its potential benefits against inflammation, carcinogenesis, atherosclerosis glucose control, and hypertension. On the other hand, the growing popularity of artificial sweeteners does not correlate with improved trends in obesity. An increased intake of artificial non-caloric sweeteners may not be associated with decreased intake of traditional sugar-sweetened beverages and foods. The effects of Stevia on weight change have been linked to bacteria in the intestinal microbiome, mainly by affecting Clostridium and Bacteroides sp. populations. A growing body of evidence indicates that Stevia rebaudiana Bertoni is protective against malignant conversion by inhibition of DNA replication in human cancer cell growth in vitro. Summary. Consumption of Stevia has demonstrated to be generally safe in most reports. Further clinical studies are warranted to determine if regular consumption brings sustained benefits for human health. |
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