Importance of high triglycerides levels between novel coronary risk factors

Introduction: The analysis of new cardiovascular risk factors is under an extensive debate in the cardiology and metabolic research fields. Objective: To determine the main factors that contribute to the classification of individuals with higher coronary risk in the adult population from Maracaibo,...

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Autores:
Bermúdez, Valmore
Salazar, Juan
Calvo, María
Martínez, María
Añez, Roberto
Rivas-Ríos, José
Chacín, Maricarmen
Hernández, Juan
Graterol, Modesto
Rojas, Joselyn
Tipo de recurso:
Fecha de publicación:
2017
Institución:
Universidad Simón Bolívar
Repositorio:
Repositorio Digital USB
Idioma:
eng
OAI Identifier:
oai:bonga.unisimon.edu.co:20.500.12442/1861
Acceso en línea:
http://hdl.handle.net/20.500.12442/1861
Palabra clave:
Lipids
Insulin
Risk factors
Prevention
Lípidos
Insulina
Factores de riesgo
Prevención
Rights
License
Licencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional
id USIMONBOL2_935cb2c6df40d471bb690c582e99592e
oai_identifier_str oai:bonga.unisimon.edu.co:20.500.12442/1861
network_acronym_str USIMONBOL2
network_name_str Repositorio Digital USB
repository_id_str
dc.title.eng.fl_str_mv Importance of high triglycerides levels between novel coronary risk factors
dc.title.alternative.spa.fl_str_mv Importancia de niveles elevados de triglicéridos entre los factores de riesgo coronario nuevos
title Importance of high triglycerides levels between novel coronary risk factors
spellingShingle Importance of high triglycerides levels between novel coronary risk factors
Lipids
Insulin
Risk factors
Prevention
Lípidos
Insulina
Factores de riesgo
Prevención
title_short Importance of high triglycerides levels between novel coronary risk factors
title_full Importance of high triglycerides levels between novel coronary risk factors
title_fullStr Importance of high triglycerides levels between novel coronary risk factors
title_full_unstemmed Importance of high triglycerides levels between novel coronary risk factors
title_sort Importance of high triglycerides levels between novel coronary risk factors
dc.creator.fl_str_mv Bermúdez, Valmore
Salazar, Juan
Calvo, María
Martínez, María
Añez, Roberto
Rivas-Ríos, José
Chacín, Maricarmen
Hernández, Juan
Graterol, Modesto
Rojas, Joselyn
dc.contributor.author.none.fl_str_mv Bermúdez, Valmore
Salazar, Juan
Calvo, María
Martínez, María
Añez, Roberto
Rivas-Ríos, José
Chacín, Maricarmen
Hernández, Juan
Graterol, Modesto
Rojas, Joselyn
dc.subject.eng.fl_str_mv Lipids
Insulin
Risk factors
Prevention
topic Lipids
Insulin
Risk factors
Prevention
Lípidos
Insulina
Factores de riesgo
Prevención
dc.subject.spa.fl_str_mv Lípidos
Insulina
Factores de riesgo
Prevención
description Introduction: The analysis of new cardiovascular risk factors is under an extensive debate in the cardiology and metabolic research fields. Objective: To determine the main factors that contribute to the classification of individuals with higher coronary risk in the adult population from Maracaibo, Venezuela. Methods: A descriptive, cross-sectional study with multistage random sampling in 1379 individuals belonging to the Maracaibo City Metabolic Syndrome Prevalence Study (MMSPS) was performed. They were classified according to the coronary risk by Framingham-Wilson equation adapted to our population. The association between various risk factors was evaluated by ordinal logistic regression models. Results: 1,379 subjects (females 55.9%; n = 771) were evaluated, 66.2% (n = 913) were classified with low coronary risk. In univariate ( 2 = 112.35; p < 0.00001) and multivariate analysis [OR: 3.98 (2.39-6.63); p < 0.01], the main factors associated to be classified as the highest risk category were hypertriglyceridemia. Conclusion: There are several factors that should be included in predictive models use worldwide. The most important in our population were dyslipidemia such as hypertriglyceridemia, hyperlipoproteinemia (a) and insulin resistance.
publishDate 2017
dc.date.issued.none.fl_str_mv 2017-11
dc.date.accessioned.none.fl_str_mv 2018-03-13T15:33:45Z
dc.date.available.none.fl_str_mv 2018-03-13T15:33:45Z
dc.type.spa.fl_str_mv article
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.identifier.issn.none.fl_str_mv 23573260
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12442/1861
identifier_str_mv 23573260
url http://hdl.handle.net/20.500.12442/1861
dc.language.iso.spa.fl_str_mv eng
language eng
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.license.spa.fl_str_mv Licencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional
rights_invalid_str_mv Licencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional
http://purl.org/coar/access_right/c_abf2
dc.publisher.spa.fl_str_mv Sociedad Colombiana de Cardiología y Cirugía Cardiovascular.
dc.source.spa.fl_str_mv Revista Colombiana de Cardiología
Vol. 24, No.6 (2017)
institution Universidad Simón Bolívar
dc.source.uri.none.fl_str_mv http://www.elsevier.es/es-revista-revista-colombiana-cardiologia-203-articulo-importance-high-triglycerides-levels-between-S0120563317300396
bitstream.url.fl_str_mv https://bonga.unisimon.edu.co/bitstreams/5e84f87b-2a74-46b5-aef0-3c9c868149c8/download
bitstream.checksum.fl_str_mv 8a4605be74aa9ea9d79846c1fba20a33
bitstream.checksumAlgorithm.fl_str_mv MD5
repository.name.fl_str_mv DSpace UniSimon
repository.mail.fl_str_mv bibliotecas@biteca.com
_version_ 1814076099005513728
spelling Licencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacionalhttp://purl.org/coar/access_right/c_abf2Bermúdez, Valmore29f9aa18-16a4-4fd3-8ce5-ed94a0b8663a-1Salazar, Juanfbd053e7-5aea-424c-812f-92153ecb9181-1Calvo, María3038ee2e-e515-49a5-ac75-96a0d81ff3c8-1Martínez, María9aa9b2df-abae-4b77-9dc6-375422bdff38-1Añez, Roberto0a8ecfdc-a89a-4435-9859-b66bba8947fa-1Rivas-Ríos, José150fd0a6-0769-46ee-8541-c44afb598193-1Chacín, Maricarmen5c3b3d7c-4444-47e2-b2be-11f08df10409-1Hernández, Juan1e343f6e-5122-40d2-b89a-7287a485337c-1Graterol, Modesto59713475-4607-4bff-90c1-a66ad9f0a173-1Rojas, Joselyn2aa91570-0516-424d-8f76-25cd7b39be6e-12018-03-13T15:33:45Z2018-03-13T15:33:45Z2017-1123573260http://hdl.handle.net/20.500.12442/1861Introduction: The analysis of new cardiovascular risk factors is under an extensive debate in the cardiology and metabolic research fields. Objective: To determine the main factors that contribute to the classification of individuals with higher coronary risk in the adult population from Maracaibo, Venezuela. Methods: A descriptive, cross-sectional study with multistage random sampling in 1379 individuals belonging to the Maracaibo City Metabolic Syndrome Prevalence Study (MMSPS) was performed. They were classified according to the coronary risk by Framingham-Wilson equation adapted to our population. The association between various risk factors was evaluated by ordinal logistic regression models. Results: 1,379 subjects (females 55.9%; n = 771) were evaluated, 66.2% (n = 913) were classified with low coronary risk. In univariate ( 2 = 112.35; p < 0.00001) and multivariate analysis [OR: 3.98 (2.39-6.63); p < 0.01], the main factors associated to be classified as the highest risk category were hypertriglyceridemia. Conclusion: There are several factors that should be included in predictive models use worldwide. The most important in our population were dyslipidemia such as hypertriglyceridemia, hyperlipoproteinemia (a) and insulin resistance.Introducción: El análisis de nuevos factores de riesgo cardiovascular constituye un tema de amplio debate en la investigación cardio-metabólica. Objetivo: Determinar los principales factores que contribuyen a la clasificación de sujetos en las categorías de mayor riesgo coronario en individuos adultos de la ciudad de Maracaibo, Venezuela. Métodos: Estudio descriptivo, trasversal con muestreo aleatorio multietapas en 1.379 individuos pertenecientes al Estudio de Prevalencia de Síndrome Metabólico de la Ciudad de Maracaibo (EPSMM). Estos fueron clasificaron de acuerdo con el riesgo coronario mediante la fórmula Framingham-Wilson adaptada para nuestra población. Se evaluó la asociación entre diversos factores de riesgo mediante un modelo de regresión logística ordinal. Resultados: Se evaluaron 1.379 sujetos (mujeres: 55,9%; n = 771), de los cuales un 66,2% (n = 913) fueron clasificados en riesgo coronario bajo. Tanto en el contexto univariante ( 2 = 112,35; p < 0,00001) como multivariante [OR: 3,98 (2,39-6,63); p < 0,01] el principal factor asociado para ser clasificado en las categorías de riesgo más elevado fue la hipertrigliceridemia. Conclusión: Existen numerosos factores que deberían ser incluidos en los modelos de predicción empleados en el mundo, en cuyo caso las dislipidemias: hipertrigliceridemia, hiperlipoproteinemia (a), e insulinorresistencia son las más importantes en nuestra población.engSociedad Colombiana de Cardiología y Cirugía Cardiovascular.Revista Colombiana de CardiologíaVol. 24, No.6 (2017)http://www.elsevier.es/es-revista-revista-colombiana-cardiologia-203-articulo-importance-high-triglycerides-levels-between-S0120563317300396LipidsInsulinRisk factorsPreventionLípidosInsulinaFactores de riesgoPrevenciónImportance of high triglycerides levels between novel coronary risk factorsImportancia de niveles elevados de triglicéridos entre los factores de riesgo coronario nuevosarticlehttp://purl.org/coar/resource_type/c_6501Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, et al. Heart disease and stroke statistics–2015 update: a report from the American Heart Association. 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Biomed Res Int. 2013;2013:650989.LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bonga.unisimon.edu.co/bitstreams/5e84f87b-2a74-46b5-aef0-3c9c868149c8/download8a4605be74aa9ea9d79846c1fba20a33MD5220.500.12442/1861oai:bonga.unisimon.edu.co:20.500.12442/18612019-04-11 21:51:42.736metadata.onlyhttps://bonga.unisimon.edu.coDSpace UniSimonbibliotecas@biteca.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