Novel Biomarkers of Diabetic Kidney Disease

Diabetic kidney disease (DKD) is a highly prevalent condition worldwide. It represents one of the most common complications arising from diabetes mellitus (DM) and is the leading cause of end-stage kidney disease (ESKD). Its development involves three fundamental components: the hemodynamic, metabolic, and inflammatory axes. Clinically, persistent albuminuria in association with a progressive decline in glomerular filtration rate (GFR) defines this disease. However, as these alterations are not specific to DKD, there is a need to discuss novel biomarkers arising from its pathogenesis which may aid in the diagnosis, follow-up, therapeutic response, and prognosis of the disease.

• Autores: Rico-Fontalvo, Jorge; Aroca-Martínez, Gustavo; Daza-Arnedo, Rodrigo; Cabrales, José; Rodríguez-Yánez, Tomás; Cardona-Blanco, María; Montejo-Hernández, Juan; Rodelo Barrios, Dairo; Patiño-Patiño, Jhonny; Osorio Rodríguez, Elber
• Fecha de publicación: 2023
• Institución: Universidad Simón Bolívar
• Repositorio: Repositorio Digital USB
• Idioma: eng
• OAI Identifier: oai:bonga.unisimon.edu.co:20.500.12442/12149
• Acceso en línea: https://hdl.handle.net/20.500.12442/12149; https://doi.org/10.3390/biom13040633; https://www.mdpi.com/2218-273X/13/4/633
• Palabra clave: Biomarkers; Diabetic kidney disease; Pathogenesis; Diabetes mellitus
• Rights: openAccess
• License: Attribution-NonCommercial-NoDerivatives 4.0 Internacional