Diagnostic criteria and management of metabolic syndrome: Evolution overtime

The beginnings of the Metabolic Syndrome (MetS) as a suspected, not yet recognized entity can be traced back to 1923 when a study concerning a particularly common clustering of metabolic entities observed in diabetic patients was first published. Years of research and endless debate yielded the curr...

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Autores:
Rojas, Edward
Castro, Ana
Manzano, Alexander
Suarez, Maria Karina
Lameda, Victor
Carrasquero, Ruben
Nava, Manuel
Bermúdez, Valmore
Tipo de recurso:
Fecha de publicación:
2020
Institución:
Universidad Simón Bolívar
Repositorio:
Repositorio Digital USB
Idioma:
eng
OAI Identifier:
oai:bonga.unisimon.edu.co:20.500.12442/13137
Acceso en línea:
https://hdl.handle.net/20.500.12442/13137
https://doi.org/10.47307/GMC.2020.128.4.5
Palabra clave:
Metabolic syndrome
Diagnostic criteria
Management
MetS updates
Cardiovascular disease
Type 2 diabetes
Síndrome metabólico
criterios diagnósticos
actualizaciones de SM
enfermedad cardiovascular
Diabetes Mellitus tipo 2
Rights
openAccess
License
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Description
Summary:The beginnings of the Metabolic Syndrome (MetS) as a suspected, not yet recognized entity can be traced back to 1923 when a study concerning a particularly common clustering of metabolic entities observed in diabetic patients was first published. Years of research and endless debate yielded the currently accepted MetS definition and diagnostic criteria, even if some components and their cut-off points are still up for discussion. To date, MetS are defined as a clustering of metabolic risk factors that greatly increase the incidence of cardiovascular disease (CVD) and type 2 diabetes (T2D), while also being closely related to various potentially deadly comorbidities. Furthermore, since early detection and management of MetS have been shown to decrease the risk for CVD and T2D, current research has focused on unifying diagnostic criteria and proposing novel parameters to facilitate MetS identification, while also promoting a healthy lifestyle as a preventive measure. With a deeper understanding of MetS pathophysiology comes the broadening of therapeutic targets open for study, thus expanding and enhancing the treatment methods currently in use. This review aims to summarize the evolution of MetS as a concept, development of the diagnostic criteria, current management, and future directions.

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