NHANES 2011–2014 Reveals Decreased Cognitive Performance in U.S. Older Adults with Metabolic Syndrome Combinations
A relationship between metabolic syndrome and cognitive impairment has been evidenced across research; however, conflicting results have been observed. A cross-sectional study was conducted on 3179 adults older than 60 from the 2011–2014 National Health and Nutrition Examination Survey (NHANES) to a...
- Autores:
-
Díaz-Camargo, Edgar
Hernández-Lalinde, Juan
Sánchez-Rubio, María
Chaparro-Suárez, Yudy
Álvarez-Caicedo, Liseth
Fierro-Zarate, Alexandra
Gravini-Donado, Marbel
García-Pacheco, Henry
Rojas-Quintero, Joselyn
Bermúdez, Valmore
- Tipo de recurso:
- Fecha de publicación:
- 2023
- Institución:
- Universidad Simón Bolívar
- Repositorio:
- Repositorio Digital USB
- Idioma:
- eng
- OAI Identifier:
- oai:bonga.unisimon.edu.co:20.500.12442/13162
- Palabra clave:
- Metabolic syndrome
Cognitive impairment
Older adults
NHANES
Obesity
Hyperglycemia
High triglycerides
Low HDL–cholesterol
- Rights
- openAccess
- License
- Attribution-NonCommercial-NoDerivatives 4.0 Internacional
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NHANES 2011–2014 Reveals Decreased Cognitive Performance in U.S. Older Adults with Metabolic Syndrome Combinations |
| title |
NHANES 2011–2014 Reveals Decreased Cognitive Performance in U.S. Older Adults with Metabolic Syndrome Combinations |
| spellingShingle |
NHANES 2011–2014 Reveals Decreased Cognitive Performance in U.S. Older Adults with Metabolic Syndrome Combinations Metabolic syndrome Cognitive impairment Older adults NHANES Obesity Hyperglycemia High triglycerides Low HDL–cholesterol |
| title_short |
NHANES 2011–2014 Reveals Decreased Cognitive Performance in U.S. Older Adults with Metabolic Syndrome Combinations |
| title_full |
NHANES 2011–2014 Reveals Decreased Cognitive Performance in U.S. Older Adults with Metabolic Syndrome Combinations |
| title_fullStr |
NHANES 2011–2014 Reveals Decreased Cognitive Performance in U.S. Older Adults with Metabolic Syndrome Combinations |
| title_full_unstemmed |
NHANES 2011–2014 Reveals Decreased Cognitive Performance in U.S. Older Adults with Metabolic Syndrome Combinations |
| title_sort |
NHANES 2011–2014 Reveals Decreased Cognitive Performance in U.S. Older Adults with Metabolic Syndrome Combinations |
| dc.creator.fl_str_mv |
Díaz-Camargo, Edgar Hernández-Lalinde, Juan Sánchez-Rubio, María Chaparro-Suárez, Yudy Álvarez-Caicedo, Liseth Fierro-Zarate, Alexandra Gravini-Donado, Marbel García-Pacheco, Henry Rojas-Quintero, Joselyn Bermúdez, Valmore |
| dc.contributor.author.none.fl_str_mv |
Díaz-Camargo, Edgar Hernández-Lalinde, Juan Sánchez-Rubio, María Chaparro-Suárez, Yudy Álvarez-Caicedo, Liseth Fierro-Zarate, Alexandra Gravini-Donado, Marbel García-Pacheco, Henry Rojas-Quintero, Joselyn Bermúdez, Valmore |
| dc.subject.eng.fl_str_mv |
Metabolic syndrome Cognitive impairment Older adults NHANES Obesity Hyperglycemia High triglycerides Low HDL–cholesterol |
| topic |
Metabolic syndrome Cognitive impairment Older adults NHANES Obesity Hyperglycemia High triglycerides Low HDL–cholesterol |
| description |
A relationship between metabolic syndrome and cognitive impairment has been evidenced across research; however, conflicting results have been observed. A cross-sectional study was conducted on 3179 adults older than 60 from the 2011–2014 National Health and Nutrition Examination Survey (NHANES) to analyze the relationship between metabolic syndrome and cognitive impairment. In our results, we found that adults with abdominal obesity, high triglycerides, and low HDL cholesterol had 4.39 fewer points in the CERAD immediate recall test than adults without any metabolic syndrome factors [Beta = −4.39, SE = 1.32, 17.75 (1.36) vs. 22.14 (0.76)]. In addition, people with this metabolic syndrome combination exhibited 2.39 fewer points in the CERAD delayed recall test than those without metabolic syndrome criteria [Beta = −2.39, SE = 0.46, 4.32 (0.49) vs. 6.71 (0.30)]. It was also found that persons with high blood pressure, hyperglycemia, and low HDL–cholesterol levels reached 4.11 points less in the animal fluency test than people with no factors [Beta = −4.11, SE = 1.55, 12.67 (2.12) vs. 16.79 (1.35)]. These findings suggest that specific metabolic syndrome combinations are essential predictors of cognitive impairment. In this study, metabolic syndrome combinations that included obesity, fasting hyperglycemia, high triglycerides, and low HDL–cholesterol were among the most frequent criteria observed. |
| publishDate |
2023 |
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2023-08-18T16:19:52Z |
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2023-08-18T16:19:52Z |
| dc.date.issued.none.fl_str_mv |
2023 |
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info:eu-repo/semantics/article |
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Artículo científico |
| dc.identifier.citation.eng.fl_str_mv |
Díaz-Camargo, E., Hernández-Lalinde, J., Sánchez-Rubio, M., Chaparro-Suárez, Y., Álvarez-Caicedo, L., Fierro-Zarate, A., Gravini-Donado, M., García-Pacheco, H., Rojas-Quintero, J., & Bermúdez, V. (2023). NHANES 2011–2014 Reveals Decreased Cognitive Performance in U.S. Older Adults with Metabolic Syndrome Combinations. International Journal of Environmental Research and Public Health, 20(7), 5257. https://doi.org/10.3390/ijerph20075257 |
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16604601 |
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https://hdl.handle.net/20.500.12442/13162 |
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https://doi.org/10.3390/ijerph20075257 |
| identifier_str_mv |
Díaz-Camargo, E., Hernández-Lalinde, J., Sánchez-Rubio, M., Chaparro-Suárez, Y., Álvarez-Caicedo, L., Fierro-Zarate, A., Gravini-Donado, M., García-Pacheco, H., Rojas-Quintero, J., & Bermúdez, V. (2023). NHANES 2011–2014 Reveals Decreased Cognitive Performance in U.S. Older Adults with Metabolic Syndrome Combinations. International Journal of Environmental Research and Public Health, 20(7), 5257. https://doi.org/10.3390/ijerph20075257 16604601 |
| url |
https://hdl.handle.net/20.500.12442/13162 https://doi.org/10.3390/ijerph20075257 |
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eng |
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Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
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Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ http://purl.org/coar/access_right/c_abf2 |
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openAccess |
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pdf |
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MDPI |
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International Journal of Environmental Research and Public Health |
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Vol. 20 Issue 7 (2023) |
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Díaz-Camargo, Edgare056554f-7c70-4102-b9c6-bad4ba6afb39Hernández-Lalinde, Juan5842fe68-7639-4999-b807-d7cea1164b1cSánchez-Rubio, María083e8ee6-94ce-4b07-87df-21ae9a7cc713Chaparro-Suárez, Yudy5d07abf5-e015-44e3-ae29-93a325d4bf2cÁlvarez-Caicedo, Liseth198da506-4370-4843-9a21-b9271789bf76Fierro-Zarate, Alexandra9fb346ef-e101-4ac0-ba55-a08d486e6e2aGravini-Donado, Marbelf5216d16-f0e2-4742-a70b-587021000208García-Pacheco, Henry784e8766-d84b-4be0-8e05-ed7c7b86b393Rojas-Quintero, Joselyn1fcd6ac1-186e-465c-a5fd-3c25563275abBermúdez, Valmore29f9aa18-16a4-4fd3-8ce5-ed94a0b8663a2023-08-18T16:19:52Z2023-08-18T16:19:52Z2023Díaz-Camargo, E., Hernández-Lalinde, J., Sánchez-Rubio, M., Chaparro-Suárez, Y., Álvarez-Caicedo, L., Fierro-Zarate, A., Gravini-Donado, M., García-Pacheco, H., Rojas-Quintero, J., & Bermúdez, V. (2023). NHANES 2011–2014 Reveals Decreased Cognitive Performance in U.S. Older Adults with Metabolic Syndrome Combinations. International Journal of Environmental Research and Public Health, 20(7), 5257. https://doi.org/10.3390/ijerph2007525716604601https://hdl.handle.net/20.500.12442/13162https://doi.org/10.3390/ijerph20075257A relationship between metabolic syndrome and cognitive impairment has been evidenced across research; however, conflicting results have been observed. A cross-sectional study was conducted on 3179 adults older than 60 from the 2011–2014 National Health and Nutrition Examination Survey (NHANES) to analyze the relationship between metabolic syndrome and cognitive impairment. In our results, we found that adults with abdominal obesity, high triglycerides, and low HDL cholesterol had 4.39 fewer points in the CERAD immediate recall test than adults without any metabolic syndrome factors [Beta = −4.39, SE = 1.32, 17.75 (1.36) vs. 22.14 (0.76)]. In addition, people with this metabolic syndrome combination exhibited 2.39 fewer points in the CERAD delayed recall test than those without metabolic syndrome criteria [Beta = −2.39, SE = 0.46, 4.32 (0.49) vs. 6.71 (0.30)]. It was also found that persons with high blood pressure, hyperglycemia, and low HDL–cholesterol levels reached 4.11 points less in the animal fluency test than people with no factors [Beta = −4.11, SE = 1.55, 12.67 (2.12) vs. 16.79 (1.35)]. These findings suggest that specific metabolic syndrome combinations are essential predictors of cognitive impairment. In this study, metabolic syndrome combinations that included obesity, fasting hyperglycemia, high triglycerides, and low HDL–cholesterol were among the most frequent criteria observed.pdfengMDPIAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2International Journal of Environmental Research and Public HealthVol. 20 Issue 7 (2023)Metabolic syndromeCognitive impairmentOlder adultsNHANESObesityHyperglycemiaHigh triglyceridesLow HDL–cholesterolNHANES 2011–2014 Reveals Decreased Cognitive Performance in U.S. Older Adults with Metabolic Syndrome Combinationsinfo:eu-repo/semantics/articleArtículo científicohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_2df8fbb1El-Tallawy, H.N.; Saadeldin, H.M.; Ezzeldin, A.M.; Tohamy, A.M.; Eltellawy, S.; Bathalath, A.M.; Shehab, M.M. Genetic, Clinical, and Biochemical Aspects of Patients with Alzheimer Disease. Egypt. J. Neurol. Psychiatry Neurosurg. 2022, 58, 24.ohnson, S.C.; Koscik, R.L.; Jonaitis, E.M.; Clark, L.R.; Mueller, K.D.; Berman, S.E.; Bendlin, B.B.; Engelman, C.D.; Okonkwo, O.C.; Hogan, K.J.; et al. The Wisconsin Registry for Alzheimer’s Prevention: A Review of Findings and Current Directions. Alzheimers Dement. 2018, 10, 130–142Wang, J.; Gu, B.J.; Masters, C.L.; Wang, Y.-J. A Systemic View of Alzheimer’s Disease—Insights from Amyloid-β Metabolism beyond the Brain. Nat. Rev. Neurol. 2017, 13, 612–623. [[PubMedBennett, D.A.; Wilson, R.S.; Boyle, P.A.; Buchman, A.S.; Schneider, J.A. Relation of Neuropathology to Cognition in Persons without Cognitive Impairment. Ann. Neurol. 2012, 72, 599–609.Katzman, R.; Terry, R.; DeTeresa, R.; Brown, T.; Davies, P.; Fuld, P.; Renbing, X.; Peck, A. Clinical, Pathological, and Neurochemical Changes in Dementia: A Subgroup with Preserved Mental Status and Numerous Neocortical Plaques. Ann. Neurol. 1988, 23, 138–14Jansen, W.J.; Ossenkoppele, R.; Knol, D.L.; Tijms, B.M.; Scheltens, P.; Verhey, F.R.J.; Visser, P.J.; Amyloid Biomarker Study Group; Aalten, P.; Aarsland, D.; et al. Prevalence of Cerebral Amyloid Pathology in Persons without Dementia: A Meta-Analysis. JAMA 2015, 313, 1924–1938.Bennett, D.A. Mixed Pathologies and Neural Reserve: Implications of Complexity for Alzheimer Disease Drug Discovery. PLoS Med. 2017, 14, e1002256. [Stern, Y. What Is Cognitive Reserve? Theory and Research Application of the Reserve Concept. J. Int. Neuropsychol. Soc. 2002, 8, 448–460.Atamna, H.; Tenore, A.; Lui, F.; Dhahbi, J.M. Organ Reserve, Excess Metabolic Capacity, and Aging. Biogerontology 2018, 19, 171–184Wang, S.; Qin, L. Homeostatic Medicine: A Strategy for Exploring Health and Disease. Curr. Med. 2022, 1, 16.Iliodromiti, S.; Iglesias Sanchez, C.; Messow, C.-M.; Cruz, M.; Garcia Velasco, J.; Nelson, S.M. Excessive Age-Related Decline in Functional Ovarian Reserve in Infertile Women: Prospective Cohort of 15,500 Women. J. Clin. Endocrinol. Metab. 2016, 101, 3548–3554Polverino, A.; Sorrentino, P.; Pesoli, M.; Mandolesi, L. Nutrition and Cognition across the Lifetime: An Overview on Epigenetic Mechanisms. AIMS Neurosci. 2021, 8, 448–476Rodgers, G.P.; Collins, F.S. Precision Nutrition—The Answer to “What to Eat to Stay Healthy”. JAMA 2020, 324, 735–736Prokopidis, K.; Giannos, P.; Ispoglou, T.; Witard, O.C.; Isanejad, M. Dietary Fiber Intake Is Associated with Cognitive Function in Older Adults: Data from the National Health and Nutrition Examination Survey. Am. J. Med. 2022, 135, E257–E262. [Mao, X.-Y.; Yin, X.-X.; Guan, Q.-W.; Xia, Q.-X.; Yang, N.; Zhou, H.-H.; Liu, Z.-Q.; Jin, W.-L. Dietary Nutrition for Neurological Disease Therapy: Current Status and Future Directions. 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