SNAr Reactions on 2-Amino-4,6-dichloropyrimidine-5-carbaldehyde
We report the experimental results of unexpected aromatic nucleophilic substitution reaction products on 2-amino-4,6-dichloropyrimidine-5-carbaldehyde. The isolated compounds are products of amination, solvolysis, and condensation processes under mild and environmentally friendly conditions, due to...
- Autores:
-
Trilleras, Jorge
- Tipo de recurso:
- Fecha de publicación:
- 2022
- Institución:
- Universidad del Atlántico
- Repositorio:
- Repositorio Uniatlantico
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.uniatlantico.edu.co:20.500.12834/767
- Acceso en línea:
- https://hdl.handle.net/20.500.12834/767
- Palabra clave:
- amination
dichloropyrimidines
aromatic substitution
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc/4.0/
| Summary: | We report the experimental results of unexpected aromatic nucleophilic substitution reaction products on 2-amino-4,6-dichloropyrimidine-5-carbaldehyde. The isolated compounds are products of amination, solvolysis, and condensation processes under mild and environmentally friendly conditions, due to the influence of structural factors of the starting pyrimidine and a high concentration of alkoxide ions. This method allows the building of pyrimidine-based compound precursors of N-heterocyclic systems. |
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